Dtna (dystrobrevin, alpha) - Rat Genome Database
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Gene: Dtna (dystrobrevin, alpha) Rattus norvegicus
Analyze
Symbol: Dtna
Name: dystrobrevin, alpha
RGD ID: 1561985
Description: Exhibits PDZ domain binding activity. Predicted to be involved in synaptic signaling. Localizes to several cellular components, including axon; extrinsic component of cytoplasmic side of plasma membrane; and sarcolemma. Human ortholog(s) of this gene implicated in cardiomyopathy and left ventricular noncompaction. Orthologous to human DTNA (dystrobrevin alpha); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Dtna-ps1; dystrobrevin alpha; dystrobrevin alpha, pseudogene 1; LOC307548; RGD1561985; similar to dystrobrevin alpha isoform 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01814,544,725 - 14,671,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1814,471,213 - 14,657,332 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01814,340,984 - 14,465,694 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41815,024,302 - 15,571,410 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1814,647,976 - 14,904,179 (+)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10545507   PMID:10995443   PMID:16448387   PMID:17728463   PMID:18468998   PMID:25931508  


Genomics

Comparative Map Data
Dtna
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01814,544,725 - 14,671,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1814,471,213 - 14,657,332 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01814,340,984 - 14,465,694 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41815,024,302 - 15,571,410 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1814,647,976 - 14,904,179 (+)NCBICelera
Cytogenetic Map18p12NCBI
DTNA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1834,493,290 - 34,891,844 (+)EnsemblGRCh38hg38GRCh38
GRCh381834,493,298 - 34,891,844 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371832,073,254 - 32,471,808 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361830,327,279 - 30,725,364 (+)NCBINCBI36hg18NCBI36
Build 341830,652,329 - 30,701,367NCBI
Celera1828,881,475 - 29,280,096 (+)NCBI
Cytogenetic Map18q12.1NCBI
HuRef1828,932,326 - 29,330,662 (+)NCBIHuRef
CHM1_11832,000,280 - 32,398,881 (+)NCBICHM1_1
Dtna
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391823,443,063 - 23,792,776 (+)NCBIGRCm39mm39
GRCm381823,310,006 - 23,659,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1823,415,135 - 23,659,715 (+)EnsemblGRCm38mm10GRCm38
MGSCv371823,573,916 - 23,818,215 (+)NCBIGRCm37mm9NCBIm37
MGSCv361823,558,452 - 23,802,724 (+)NCBImm8
Celera1823,912,218 - 24,156,253 (+)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1812.08NCBI
Dtna
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540221,315,889 - 21,673,044 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540221,414,122 - 21,676,389 (+)NCBIChiLan1.0ChiLan1.0
DTNA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11831,297,078 - 31,705,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1831,524,255 - 31,705,386 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01827,706,576 - 28,116,328 (+)NCBIMhudiblu_PPA_v0panPan3
DTNA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl755,069,462 - 55,420,259 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1755,068,555 - 55,420,377 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dtna
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493651710,105,767 - 10,357,672 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTNA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6118,333,733 - 118,753,513 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16118,333,069 - 118,753,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26110,934,485 - 111,005,318 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DTNA
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11845,855,444 - 46,253,842 (-)NCBI
ChlSab1.1 Ensembl1845,856,403 - 45,991,102 (-)Ensembl
Dtna
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247798,948,578 - 9,329,459 (+)NCBI

Position Markers
D18Rat148  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,635,186 - 14,635,321NCBIRnor6.0
Rnor_5.01814,429,773 - 14,429,908UniSTSRnor5.0
RGSC_v3.41815,540,790 - 15,540,925UniSTSRGSC3.4
RGSC_v3.41815,540,789 - 15,540,925RGDRGSC3.4
RGSC_v3.11815,567,436 - 15,567,571RGD
Celera1814,868,052 - 14,868,187UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18173.4RGD
RH 3.4 Map18173.4UniSTS
RH 2.0 Map18712.7RGD
SHRSP x BN Map184.19RGD
BF416056  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,316,736 - 14,316,958NCBIRnor6.0
Rnor_5.01814,105,980 - 14,106,202UniSTSRnor5.0
RGSC_v3.41815,036,654 - 15,036,876UniSTSRGSC3.4
Celera1814,561,293 - 14,561,515UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18153.11UniSTS
Dtna  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,671,226 - 14,671,437NCBIRnor6.0
Rnor_6.01814,671,226 - 14,671,669NCBIRnor6.0
Rnor_5.01814,465,409 - 14,465,852UniSTSRnor5.0
Rnor_5.01814,465,409 - 14,465,620UniSTSRnor5.0
RGSC_v3.41815,577,516 - 15,577,727UniSTSRGSC3.4
Celera1814,903,891 - 14,904,102UniSTS
Cytogenetic Map18p12UniSTS
RH132038  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,616,682 - 14,618,171NCBIRnor6.0
Rnor_5.01814,411,269 - 14,412,758UniSTSRnor5.0
RGSC_v3.41815,522,286 - 15,523,775UniSTSRGSC3.4
Celera1814,849,548 - 14,851,037UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18172.9UniSTS
RH142852  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,645,995 - 14,646,114NCBIRnor6.0
Rnor_5.01814,440,582 - 14,440,701UniSTSRnor5.0
RGSC_v3.41815,551,599 - 15,551,718UniSTSRGSC3.4
Celera1814,878,861 - 14,878,980UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18173.4UniSTS
BE096939  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,670,934 - 14,671,110NCBIRnor6.0
Rnor_5.01814,465,117 - 14,465,293UniSTSRnor5.0
RGSC_v3.41815,577,224 - 15,577,400UniSTSRGSC3.4
Celera1814,903,599 - 14,903,775UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18174.0UniSTS
RH137649  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,647,567 - 14,647,708NCBIRnor6.0
Rnor_5.01814,442,154 - 14,442,295UniSTSRnor5.0
RGSC_v3.41815,553,171 - 15,553,312UniSTSRGSC3.4
Celera1814,880,433 - 14,880,574UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18172.0UniSTS
BE119476  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,523,940 - 14,524,104NCBIRnor6.0
Rnor_5.01814,319,640 - 14,319,804UniSTSRnor5.0
RGSC_v3.41815,431,404 - 15,431,568UniSTSRGSC3.4
Celera1814,754,727 - 14,754,891UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18172.7UniSTS
AI228002  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,668,162 - 14,668,311NCBIRnor6.0
Rnor_5.01814,462,345 - 14,462,494UniSTSRnor5.0
RGSC_v3.41815,574,452 - 15,574,601UniSTSRGSC3.4
Celera1814,900,827 - 14,900,976UniSTS
Cytogenetic Map18p12UniSTS
RH 3.4 Map18174.0UniSTS
RH26327  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,647,517 - 14,647,679NCBIRnor6.0
Rnor_5.01814,442,104 - 14,442,266UniSTSRnor5.0
RGSC_v3.41815,553,121 - 15,553,283UniSTSRGSC3.4
Celera1814,880,383 - 14,880,545UniSTS
Cytogenetic Map18p12UniSTS
UniSTS:257001  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01814,409,712 - 14,409,862NCBIRnor6.0
Rnor_5.01814,200,093 - 14,200,243UniSTSRnor5.0
Celera1814,648,057 - 14,648,207UniSTS
Cytogenetic Map18p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18125999214Rat
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18125999214Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135097280Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18138195967Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18138195967Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18138753381Rat
1641910Colcr3Colorectal carcinoma resistance QTL 35.020.000007intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor surface area measurement (CMO:0002078)18247709623184414Rat
1641910Colcr3Colorectal carcinoma resistance QTL 35.020.000007intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)18247709623184414Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18371954732487870Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18440751362570466Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18543013441781619Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18705776915274626Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18705776915274626Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18705776915274626Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18705776915274626Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18705776915274626Rat
70178EaezExperimental allergic encephalomyelitis QTL z2.4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)181259717915099007Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:565
Count of miRNA genes:227
Interacting mature miRNAs:267
Transcripts:ENSRNOT00000033573, ENSRNOT00000040198, ENSRNOT00000045224, ENSRNOT00000045918, ENSRNOT00000050975, ENSRNOT00000072596, ENSRNOT00000074129
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 23 8 10 40 12 5 8
Low 3 20 13 1 10 1 1 34 35 25 6
Below cutoff 26 22 9 22 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006222516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07031442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07031443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07031444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01094062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000045224   ⟹   ENSRNOP00000042067
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1814,471,213 - 14,657,332 (+)Ensembl
RefSeq Acc Id: XM_006222516   ⟹   XP_006222578
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1814,647,985 - 14,856,042 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006222517   ⟹   XP_006222579
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1814,647,976 - 14,904,179 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017587849   ⟹   XP_017443338
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1814,647,980 - 14,890,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017587850   ⟹   XP_017443339
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1814,647,983 - 14,856,042 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601078   ⟹   XP_017456567
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01814,544,725 - 14,671,514 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601079   ⟹   XP_017456568
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01814,544,728 - 14,648,788 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601080   ⟹   XP_017456569
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01814,544,729 - 14,648,788 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601081   ⟹   XP_017456570
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01814,544,730 - 14,648,788 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601082   ⟹   XP_017456571
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01814,544,729 - 14,618,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601083   ⟹   XP_017456572
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01814,544,730 - 14,618,276 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_006222579   ⟸   XM_006222517
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_006222578   ⟸   XM_006222516
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017443338   ⟸   XM_017587849
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017443339   ⟸   XM_017587850
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017456567   ⟸   XM_017601078
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456568   ⟸   XM_017601079
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456569   ⟸   XM_017601080
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017456571   ⟸   XM_017601082
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017456570   ⟸   XM_017601081
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017456572   ⟸   XM_017601083
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000042067   ⟸   ENSRNOT00000045224
Protein Domains
ZZ-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561985 AgrOrtholog
Ensembl Genes ENSRNOG00000016671 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042067 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045224 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.90 UniProtKB/TrEMBL
InterPro Distrobrevin UniProtKB/TrEMBL
  EF-hand-like_dom UniProtKB/TrEMBL
  EF-hand_dom_typ1 UniProtKB/TrEMBL
  EF-hand_dom_typ2 UniProtKB/TrEMBL
  Znf_ZZ UniProtKB/TrEMBL
  Znf_ZZ_sf UniProtKB/TrEMBL
NCBI Gene 307548 ENTREZGENE
Pfam efhand_1 UniProtKB/TrEMBL
  efhand_2 UniProtKB/TrEMBL
  PF00569 UniProtKB/TrEMBL
PhenoGen Dtna PhenoGen
PIRSF Distrobrevin UniProtKB/TrEMBL
PROSITE ZF_ZZ_1 UniProtKB/TrEMBL
  ZF_ZZ_2 UniProtKB/TrEMBL
SMART ZnF_ZZ UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt D4A772_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-06 Dtna  dystrobrevin, alpha  Dtna-ps1  dystrobrevin alpha, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Dtna-ps1  dystrobrevin alpha, pseudogene 1  Dtna  dystrobrevin alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dtna  dystrobrevin alpha   Dtna_predicted  dystrobrevin alpha (predicted)  'predicted' is removed 2292626 APPROVED
2006-08-31 Dtna_predicted  dystrobrevin alpha (predicted)  RGD1561985_predicted  similar to dystrobrevin alpha isoform 1 (predicted)  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561985_predicted  similar to dystrobrevin alpha isoform 1 (predicted)  LOC307548  similar to dystrobrevin alpha isoform 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307548  similar to dystrobrevin alpha isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL