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Gene: Pcna (proliferating cell nuclear antigen) Rattus norvegicus
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Symbol: Pcna
Name: proliferating cell nuclear antigen
Description: Exhibits estrogen receptor binding activity. Involved in several processes, including estrous cycle; liver regeneration; and response to dexamethasone. Localizes to the nucleus. Biomarker of several diseases, including brain ischemia (multiple); mucositis; obstructive jaundice; osteoporosis; and sciatic neuropathy. Orthologous to human PCNA (proliferating cell nuclear antigen); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; base excision repair pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cyclin; Pcna/cyclin; PCNAR
Orthologs:
Homo sapiens (human) : PCNA (proliferating cell nuclear antigen)  HGNC  Alliance
Mus musculus (house mouse) : Pcna (proliferating cell nuclear antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcna (proliferating cell nuclear antigen)
Pan paniscus (bonobo/pygmy chimpanzee) : PCNA (proliferating cell nuclear antigen)
Canis lupus familiaris (dog) : PCNA (proliferating cell nuclear antigen)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcna (proliferating cell nuclear antigen)
Sus scrofa (pig) : PCNA (proliferating cell nuclear antigen)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03124,880,698 - 124,884,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03131,376,235 - 131,380,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43120,008,715 - 120,012,589 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13119,914,289 - 119,918,243 (-)NCBI
Celera3118,296,567 - 118,300,439 (-)NCBICelera
Cytogenetic Map3q36NCBI
RH 3.4 Map31023.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pcna
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3269
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.