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Gene: PCNA (proliferating cell nuclear antigen) Homo sapiens
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Symbol: PCNA
Name: proliferating cell nuclear antigen
Description: Exhibits several functions, including DNA binding activity; MutLalpha complex binding activity; and enzyme binding activity. Involved in several processes, including DNA repair; cellular response to UV; and positive regulation of macromolecule metabolic process. Localizes to several cellular components, including the PCNA complex; centrosome; and nucleus. Biomarker of Lewy body dementia; invasive ductal carcinoma; kidney cancer (multiple); leiomyoma; and seminoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATLD2; cyclin; DNA polymerase delta auxiliary protein; MGC8367
Orthologs:
Mus musculus (house mouse) : Pcna (proliferating cell nuclear antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pcna (proliferating cell nuclear antigen)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcna (proliferating cell nuclear antigen)
Pan paniscus (bonobo/pygmy chimpanzee) : PCNA (proliferating cell nuclear antigen)
Canis lupus familiaris (dog) : PCNA (proliferating cell nuclear antigen)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcna (proliferating cell nuclear antigen)
Sus scrofa (pig) : PCNA (proliferating cell nuclear antigen)
more info ...
Related Pseudogenes: PCNAP1   PCNAP2   PCNAP3   PCNAP4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38205,114,953 - 5,126,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37205,095,599 - 5,107,268 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36205,043,599 - 5,055,268 (-)NCBINCBI36hg18NCBI36
Build 34205,043,598 - 5,048,647NCBI
Celera205,165,620 - 5,177,289 (-)NCBI
Cytogenetic Map20p12.3NCBI
HuRef205,049,534 - 5,061,197 (-)NCBIHuRef
CHM1_1205,096,983 - 5,108,646 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PCNA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732094
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.