PCNA (proliferating cell nuclear antigen) - Rat Genome Database

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Gene: PCNA (proliferating cell nuclear antigen) Homo sapiens
Analyze
Symbol: PCNA
Name: proliferating cell nuclear antigen
RGD ID: 732094
HGNC Page HGNC
Description: Exhibits several functions, including DNA binding activity; MutLalpha complex binding activity; and enzyme binding activity. Involved in several processes, including DNA repair; positive regulation of DNA metabolic process; and positive regulation of DNA replication. Localizes to centrosome; chromatin; and nucleus. Biomarker of Lewy body dementia; invasive ductal carcinoma; kidney cancer (multiple); leiomyoma; and seminoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATLD2; cyclin; DNA polymerase delta auxiliary protein; MGC8367
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: PCNAP1   PCNAP2   PCNAP3   PCNAP4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl205,114,953 - 5,126,626 (-)EnsemblGRCh38hg38GRCh38
GRCh38205,114,953 - 5,126,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37205,095,599 - 5,107,268 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36205,043,599 - 5,055,268 (-)NCBINCBI36hg18NCBI36
Build 34205,043,598 - 5,048,647NCBI
Celera205,165,620 - 5,177,289 (-)NCBI
Cytogenetic Map20p12.3NCBI
HuRef205,049,534 - 5,061,197 (-)NCBIHuRef
CHM1_1205,096,983 - 5,108,646 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(+)-pilocarpine  (ISO)
(+)-taxifolin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(-)-quinic acid  (EXP)
(R)-lipoic acid  (ISO)
(R)-mevalonic acid  (EXP)
(S)-nicotine  (EXP,ISO)
(Z)-3-butylidenephthalide  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichlorobenzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-thiazolidine-2,4-dione  (EXP)
1,4-dichlorobenzene  (ISO)
1,4-dioxane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-D  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-acetamidofluorene  (ISO)
2-nitrofluorene  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid  (ISO)
3-aminobenzamide  (ISO)
3-BROMO-7-NITROINDAZOLE  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nonylphenol  (EXP,ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (ISO)
5-fluorouracil  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
5-methyltetrahydrofolic acid  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
acetamide  (ISO)
acetic acid  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP,ISO)
afimoxifene  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
allethrin  (ISO)
alpha-amanitin  (EXP)
alpha-hexachlorocyclohexane  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
alvocidib  (EXP)
amifostine  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphibole asbestos  (EXP)
andrographolide  (ISO)
aniline  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apigenin  (EXP)
apocynin  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite ion  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
asiatic acid  (ISO)
atrazine  (EXP)
atropine  (EXP)
avobenzone  (EXP)
azadirachtin A  (EXP)
azathioprine  (EXP)
bafilomycin A1  (EXP)
bathocuproine disulfonic acid  (EXP)
benazepril  (ISO)
benzamide  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
Besigomsin  (ISO)
beta-aminopropionitrile  (EXP)
beta-naphthoflavone  (ISO)
beta-tocopherol  (ISO)
betulinic acid  (EXP)
bezafibrate  (ISO)
bicalutamide  (EXP)
biphenyl-4-amine  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
boric acid  (ISO)
boron atom  (ISO)
bromocriptine  (ISO)
bromodichloromethane  (ISO)
bromoform  (ISO)
brucine  (ISO)
budesonide  (ISO)
buspirone  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcidiol  (EXP)
calcitriol  (EXP,ISO)
camostat  (ISO)
captafol  (ISO)
carbamate ester  (ISO)
carbon nanotube  (ISO)
carboplatin  (EXP,ISO)
cefaloridine  (ISO)
celastrol  (ISO)
celecoxib  (ISO)
cerium trichloride  (EXP)
chelerythrine  (ISO)
Chlorodibromomethane  (ISO)
chloroform  (ISO)
chlorogenic acid  (ISO)
cholic acid  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
chrysophanol  (EXP)
cilostazol  (EXP)
Cinobufagin  (EXP)
cisplatin  (EXP,ISO)
citral  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
coenzyme Q10  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
corticosterone  (ISO)
cortisol  (EXP)
costunolide  (ISO)
coumarin  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
CU-O LINKAGE  (EXP,ISO)
curcumin  (EXP,ISO)
cyanidin cation  (ISO)
cyclohexanols  (ISO)
cycloheximide  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyhalothrin  (ISO)
cylindrospermopsin  (EXP)
cypermethrin  (ISO)
cyprodinil  (EXP)
D-glucose  (EXP,ISO)
daidzein  (EXP,ISO)
dapoxetine  (ISO)
decabromodiphenyl ether  (ISO)
delta-tocopherol  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (EXP)
diamminedichloroplatinum  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (EXP,ISO)
dichlorine  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (EXP)
dicrotophos  (EXP)
dieckol  (EXP)
dieldrin  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (ISO)
diheptyl phthalate  (ISO)
dihydroxyacetone  (EXP)
dimethylarsinic acid  (ISO)
diosmin  (ISO)
dioxygen  (EXP)
disodium selenite  (EXP)
doxorubicin  (EXP,ISO)
elemental boron  (ISO)
elemental selenium  (EXP)
ellagic acid  (ISO)
embelin  (EXP)
emodin  (ISO)
endosulfan  (EXP)
Enterolactone  (EXP)
entinostat  (ISO)
enzacamene  (EXP)
enzyme inhibitor  (EXP)
Estragole  (ISO)
ethanol  (ISO)
eugenol  (ISO)
famotidine  (ISO)
fenofibrate  (EXP,ISO)
fenvalerate  (ISO)
finasteride  (ISO)
fipronil  (ISO)
fludioxonil  (EXP)
flutamide  (ISO)
folic acid  (ISO)
fulvestrant  (EXP,ISO)
furan  (ISO)
gallic acid  (ISO)
gamma-linolenic acid  (EXP)
gamma-tocopherol  (ISO)
gefitinib  (ISO)
gemfibrozil  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
geranial  (ISO)
geraniol  (ISO)
glucaric acid  (ISO)
glucose  (EXP,ISO)
glycitein  (EXP)
glyphosate  (EXP)
hesperetin  (ISO)
hesperidin  (ISO)
hexachlorobenzene  (EXP,ISO)
histamine  (ISO)
hydralazine  (ISO)
hydrochlorothiazide  (ISO)
hydrogen chloride  (EXP)
hydrogen peroxide  (EXP)
hydroxyurea  (EXP)
indometacin  (EXP,ISO)
irinotecan  (ISO)
iron atom  (ISO)
iron dextran  (ISO)
iron(0)  (ISO)
iron(III) nitrilotriacetate  (ISO)
isoflavones  (ISO)
juglone  (EXP)
kaempferol  (ISO)
kojic acid  (ISO)
L-ascorbic acid  (ISO)
L-cysteine  (ISO)
leflunomide  (EXP)
limonene  (ISO)
linsidomine  (ISO)
linuron  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
lupeol  (ISO)
LY 364947  (ISO)
LY294002  (ISO)
lycopene  (ISO)
mabuterol  (ISO)
malachite green cation  (ISO)
malathion  (EXP)
maneb  (ISO)
masoprocol  (ISO)
Mecamylamine  (EXP)
mechlorethamine  (ISO)
melatonin  (EXP,ISO)
meloxicam  (EXP)
menadione  (EXP,ISO)
methapyrilene  (ISO)
methimazole  (EXP,ISO)
methotrexate  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylseleninic acid  (EXP)
methyltestosterone  (ISO)
miconazole  (ISO)
mitomycin C  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
myricitrin  (ISO)
N'-Nitrosonornicotine  (EXP)
N,N-bis(2-hydroxypropyl)nitrosamine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (EXP)
nelfinavir  (EXP)
nickel atom  (EXP)
nickel sulfate  (EXP)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitrofen  (EXP,ISO)
nitrogen dioxide  (ISO)
Nutlin-3  (EXP)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
oleanolic acid  (ISO)
omeprazole  (ISO)
ouabain  (EXP)
ozone  (ISO)
paclitaxel  (EXP,ISO)
palbociclib  (EXP)
pantoprazole  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (EXP)
PD 0325901  (ISO)
pentachlorophenol  (ISO)
perfluorobutyric acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pinosylvin  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
piroxicam  (EXP)
poly(propylene imine) macromolecule  (EXP)
potassium dichromate  (ISO)
potassium iodide  (ISO)
potassium nitrate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
probucol  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
pterostilbene  (ISO)
pyrithione  (ISO)
pyrogallol  (ISO)
pyrrolidine dithiocarbamate  (EXP)
quercetin  (EXP,ISO)
raloxifene  (EXP,ISO)
Rebamipide  (ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
royal jelly  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
scutellarin  (EXP)
selenium atom  (EXP)
selenomethionine  (ISO)
serpentine asbestos  (ISO)
shikimic acid  (EXP)
Shikonin  (ISO)
silibinin  (ISO)
silicon dioxide  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
silver(1+) nitrate  (EXP)
simvastatin  (EXP)
sirolimus  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
stavudine  (ISO)
streptozocin  (ISO)
sulfasalazine  (ISO)
sulforaphane  (EXP)
sulindac  (ISO)
sulindac sulfone  (ISO)
sunitinib  (EXP)
Swertiamarin  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tamibarotene  (EXP)
tamoxifen  (EXP,ISO)
taurine  (ISO)
terephthalic acid  (ISO)
testosterone  (EXP,ISO)
tetrachlorohydroquinone  (ISO)
tetrachloromethane  (ISO)
tetrathiomolybdate(2-)  (EXP)
thapsigargin  (EXP)
thioacetamide  (ISO)
thymoquinone  (ISO)
thyroxine  (EXP)
titanium dioxide  (EXP,ISO)
tocopherol  (ISO)
tolcapone  (ISO)
toluene 2,4-diisocyanate  (ISO)
Tomentosin  (EXP)
topotecan  (EXP)
trans-pinosylvin  (EXP)
transplatin  (EXP)
trichloroacetic acid  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
trimethylarsine oxide  (ISO)
troglitazone  (EXP,ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP)
tungsten  (ISO)
tunicamycin  (EXP,ISO)
tyrphostin AG 1478  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vancomycin  (ISO)
vinyl carbamate  (ISO)
vitamin E  (ISO)
Y-27632  (EXP)
zerumbone  (ISO)
zidovudine  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)
zingerone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
base-excision repair, gap-filling  (ISO,TAS)
cellular response to hydrogen peroxide  (IEA,ISO)
cellular response to UV  (IDA,ISO)
cellular response to xenobiotic stimulus  (IEA,ISO)
DNA damage response, detection of DNA damage  (TAS)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  (TAS)
epithelial cell differentiation  (IEP)
error-free translesion synthesis  (TAS)
error-prone translesion synthesis  (TAS)
estrous cycle  (IEA,ISO)
heart development  (IEA,ISO)
leading strand elongation  (IBA)
liver regeneration  (IEA,ISO)
mismatch repair  (IBA,IDA,TAS)
mitotic telomere maintenance via semi-conservative replication  (ISS)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
nucleotide-excision repair, DNA gap filling  (TAS)
nucleotide-excision repair, DNA incision  (TAS)
nucleotide-excision repair, DNA incision, 5'-to lesion  (TAS)
positive regulation of deoxyribonuclease activity  (IDA)
positive regulation of DNA repair  (IMP)
positive regulation of DNA replication  (IMP)
positive regulation of DNA-directed DNA polymerase activity  (IMP)
protein ubiquitination  (TAS)
regulation of transcription involved in G1/S transition of mitotic cell cycle  (TAS)
replication fork processing  (ISS)
response to cadmium ion  (IEA,ISO)
response to dexamethasone  (IEA,ISO)
response to estradiol  (IEA,ISO)
response to L-glutamate  (IEA,ISO)
response to lipid  (ISO)
response to oxidative stress  (ISO)
telomere maintenance  (TAS)
telomere maintenance via semi-conservative replication  (TAS)
transcription-coupled nucleotide-excision repair  (TAS)
translesion synthesis  (IBA,IDA,TAS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Amare Kadam PS, etal., Cancer Genet Cytogenet. 2001 Mar;125(2):139-46.
2. Arnaiz MR, etal., J Parasitol. 2002 Oct;88(5):919-25.
3. Deng X, etal., J Mol Histol. 2012 Dec;43(6):669-79. doi: 10.1007/s10735-012-9450-y. Epub 2012 Sep 27.
4. Frierson HF Jr Mod Pathol. 1993 May;6(3):290-4.
5. GOA_HUMAN data from the GO Consortium
6. Hassan MH, etal., Hum Reprod. 2011 Nov;26(11):3008-18. doi: 10.1093/humrep/der280. Epub 2011 Sep 6.
7. Hedglin M, etal., Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a010165. doi: 10.1101/cshperspect.a010165.
8. Hori K, etal., Pathol Int. 1997 May;47(5):282-7.
9. Imai H, etal., Eur J Neurosci 2002 Jun;15(12):1929-36.
10. Johnson M, etal., Hippocampus. 2011 Oct;21(10):1126-36. doi: 10.1002/hipo.20826. Epub 2010 Jul 21.
11. Kayisli UA, etal., Reprod Sci. 2007 Oct;14(7):678-86.
12. Li GM Cell Res. 2008 Jan;18(1):85-98.
13. Liu FS, etal., Zhonghua Yi Xue Za Zhi (Taipei). 1999 Oct;62(10):695-702.
14. Liu YC and Bambara RA, Biochem Biophys Res Commun. 1989 Jun 15;161(2):873-82.
15. Moldovan GL, etal., Cell. 2007 May 18;129(4):665-79.
16. Morishita R, etal., Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8474-8.
17. Niu Y, etal., Zhonghua Bing Li Xue Za Zhi. 1997 Dec;26(6):337-9.
18. Ohyama C, etal., Nippon Hinyokika Gakkai Zasshi. 1995 Oct;86(10):1543-51.
19. Pipeline to import KEGG annotations from KEGG into RGD
20. Pipeline to import SMPDB annotations from SMPDB into RGD
21. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. RGD automated import pipeline for gene-chemical interactions
23. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
24. Sheen-Chen SM, etal., World J Surg. 2003 Oct;27(10):1161-4. Epub 2003 Aug 18.
25. Skotnicka-Klonowicz G, etal., Eur J Surg Oncol. 2002 Feb;28(1):67-71.
26. Tahan SR, etal., Cancer. 1993 Jun 1;71(11):3552-9.
27. Tazuke Y, etal., Pediatr Surg Int. 2011 Feb;27(2):151-8. doi: 10.1007/s00383-010-2798-8.
28. Theocharis SE, etal., Dig Dis Sci. 1994 Feb;39(2):245-52.
29. Tomasevic G, etal., Brain Res Mol Brain Res. 1998 Oct 1;60(2):168-76.
30. Tousson E, etal., Reprod Sci. 2011 Jul;18(7):679-86. doi: 10.1177/1933719110395401. Epub 2011 Jan 27.
31. Yu SJ, etal., Exp Biol Med (Maywood). 2012 Apr;237(4):395-406. doi: 10.1258/ebm.2011.011217.
32. Zafar H and Ali S, Arch Biochem Biophys. 2013 Jan 15;529(2):66-74. doi: 10.1016/j.abb.2012.11.008. Epub 2012 Dec 3.
Additional References at PubMed
PMID:1313560   PMID:1477073   PMID:1975809   PMID:1979311   PMID:2565339   PMID:2569765   PMID:2882422   PMID:2882507   PMID:7478510   PMID:7673186   PMID:7673244   PMID:7780738  
PMID:7784094   PMID:7821789   PMID:7903056   PMID:7908906   PMID:7911228   PMID:7915843   PMID:7949095   PMID:7973727   PMID:8093561   PMID:8101826   PMID:8103281   PMID:8259215  
PMID:8647134   PMID:8662825   PMID:8668533   PMID:8673466   PMID:8858149   PMID:8861913   PMID:8861969   PMID:8876181   PMID:8995762   PMID:8999859   PMID:9087533   PMID:9092549  
PMID:9111189   PMID:9178907   PMID:9228079   PMID:9302295   PMID:9305916   PMID:9396813   PMID:9465025   PMID:9467962   PMID:9545252   PMID:9545286   PMID:9546435   PMID:9552415  
PMID:9563011   PMID:9566895   PMID:9570268   PMID:9632134   PMID:9649448   PMID:9667749   PMID:9705499   PMID:9751713   PMID:9774970   PMID:9822671   PMID:9927044   PMID:10022118  
PMID:10051561   PMID:10219083   PMID:10353443   PMID:10393198   PMID:10408173   PMID:10455148   PMID:10463569   PMID:10477523   PMID:10559261   PMID:10648606   PMID:10828065   PMID:10858286  
PMID:10871373   PMID:10873631   PMID:10888872   PMID:10930425   PMID:10973963   PMID:10978339   PMID:11005803   PMID:11022036   PMID:11077446   PMID:11092888   PMID:11239001   PMID:11254741  
PMID:11268218   PMID:11274057   PMID:11302688   PMID:11310559   PMID:11313979   PMID:11328591   PMID:11350925   PMID:11376153   PMID:11411798   PMID:11430825   PMID:11463845   PMID:11473323  
PMID:11554927   PMID:11559705   PMID:11578332   PMID:11585903   PMID:11593007   PMID:11595739   PMID:11601988   PMID:11682605   PMID:11724965   PMID:11741962   PMID:11780052   PMID:11784855  
PMID:11805113   PMID:11864421   PMID:11877408   PMID:11896603   PMID:11929879   PMID:11968016   PMID:11986310   PMID:11994305   PMID:12015309   PMID:12045192   PMID:12063248   PMID:12081642  
PMID:12088102   PMID:12124778   PMID:12125971   PMID:12171929   PMID:12192049   PMID:12220650   PMID:12226657   PMID:12237462   PMID:12354094   PMID:12361598   PMID:12368291   PMID:12382578  
PMID:12390713   PMID:12393188   PMID:12400013   PMID:12403614   PMID:12439914   PMID:12452045   PMID:12452062   PMID:12477932   PMID:12479101   PMID:12515622   PMID:12522211   PMID:12532471  
PMID:12632497   PMID:12633936   PMID:12750383   PMID:12766176   PMID:12782299   PMID:12786946   PMID:12853968   PMID:12857440   PMID:12893285   PMID:12930846   PMID:12937166   PMID:12947108  
PMID:12964161   PMID:14558955   PMID:14612290   PMID:14642618   PMID:14657243   PMID:14669354   PMID:14676842   PMID:14729473   PMID:14871261   PMID:14871894   PMID:14988403   PMID:15000866  
PMID:15033825   PMID:15050687   PMID:15107487   PMID:15149598   PMID:15161643   PMID:15221970   PMID:15225546   PMID:15342632   PMID:15358233   PMID:15359278   PMID:15489334   PMID:15494374  
PMID:15504738   PMID:15536154   PMID:15543136   PMID:15550930   PMID:15572421   PMID:15576034   PMID:15595847   PMID:15616578   PMID:15617346   PMID:15635413   PMID:15638377   PMID:15638382  
PMID:15647383   PMID:15681588   PMID:15754413   PMID:15772596   PMID:15777783   PMID:15805117   PMID:15831485   PMID:15924676   PMID:15967114   PMID:16000169   PMID:16082198   PMID:16101161  
PMID:16124066   PMID:16174846   PMID:16189514   PMID:16195237   PMID:16201313   PMID:16204460   PMID:16216273   PMID:16216562   PMID:16226712   PMID:16226749   PMID:16227586   PMID:16248462  
PMID:16288740   PMID:16357261   PMID:16362051   PMID:16388758   PMID:16407242   PMID:16407252   PMID:16438930   PMID:16463680   PMID:16474839   PMID:16482215   PMID:16508013   PMID:16510448  
PMID:16512489   PMID:16531995   PMID:16551699   PMID:16552335   PMID:16584090   PMID:16609022   PMID:16611994   PMID:16616141   PMID:16710452   PMID:16763556   PMID:16826239   PMID:16861890  
PMID:16861906   PMID:16888288   PMID:16888649   PMID:16888766   PMID:16934511   PMID:16964240   PMID:16982685   PMID:17063386   PMID:17065558   PMID:17106521   PMID:17108083   PMID:17115032  
PMID:17148452   PMID:17164758   PMID:17167529   PMID:17203305   PMID:17274640   PMID:17274954   PMID:17285972   PMID:17298749   PMID:17342744   PMID:17507928   PMID:17525639   PMID:17564317  
PMID:17588519   PMID:17720188   PMID:17720710   PMID:17828505   PMID:17880707   PMID:17927850   PMID:17932049   PMID:17955473   PMID:17982625   PMID:18029348   PMID:18032376   PMID:18072009  
PMID:18082604   PMID:18086887   PMID:18162470   PMID:18162579   PMID:18166648   PMID:18184650   PMID:18245774   PMID:18256758   PMID:18263614   PMID:18279620   PMID:18284681   PMID:18312749  
PMID:18316726   PMID:18319261   PMID:18321066   PMID:18326858   PMID:18331714   PMID:18353733   PMID:18448427   PMID:18451105   PMID:18481002   PMID:18498247   PMID:18499658   PMID:18509272  
PMID:18510217   PMID:18521065   PMID:18562274   PMID:18604718   PMID:18662981   PMID:18669164   PMID:18676680   PMID:18692475   PMID:18719106   PMID:18765913   PMID:18794347   PMID:18799611  
PMID:18839537   PMID:18845679   PMID:18853184   PMID:18931444   PMID:18948756   PMID:18949048   PMID:18954305   PMID:19001268   PMID:19012493   PMID:19067003   PMID:19104052   PMID:19125419  
PMID:19130399   PMID:19135898   PMID:19150984   PMID:19156526   PMID:19170196   PMID:19182791   PMID:19208623   PMID:19221475   PMID:19237606   PMID:19285961   PMID:19339270   PMID:19342888  
PMID:19351509   PMID:19419956   PMID:19424044   PMID:19443450   PMID:19460716   PMID:19481339   PMID:19483288   PMID:19505873   PMID:19523882   PMID:19536092   PMID:19550124   PMID:19595719  
PMID:19625176   PMID:19628465   PMID:19692168   PMID:19704162   PMID:19714462   PMID:19730436   PMID:19734146   PMID:19738201   PMID:19789190   PMID:19822659   PMID:19834596   PMID:19845771  
PMID:19851886   PMID:19885588   PMID:19895739   PMID:19895794   PMID:19950226   PMID:19995904   PMID:20004149   PMID:20029092   PMID:20061190   PMID:20064529   PMID:20071335   PMID:20085707  
PMID:20128380   PMID:20129057   PMID:20129063   PMID:20147293   PMID:20150366   PMID:20159558   PMID:20211058   PMID:20226869   PMID:20227374   PMID:20302655   PMID:20303835   PMID:20350215  
PMID:20351267   PMID:20360068   PMID:20385554   PMID:20394503   PMID:20423048   PMID:20453000   PMID:20457750   PMID:20458337   PMID:20460379   PMID:20496165   PMID:20522537   PMID:20528769  
PMID:20541997   PMID:20543468   PMID:20574454   PMID:20580447   PMID:20580881   PMID:20600238   PMID:20603015   PMID:20605778   PMID:20606006   PMID:20613874   PMID:20675655   PMID:20729856  
PMID:20733054   PMID:20803149   PMID:20823236   PMID:20826785   PMID:20848772   PMID:20849852   PMID:20932471   PMID:20937699   PMID:20940144   PMID:20975039   PMID:21031434   PMID:21035370  
PMID:21045206   PMID:21081666   PMID:21145461   PMID:21149733   PMID:21209461   PMID:21220508   PMID:21227930   PMID:21254647   PMID:21255825   PMID:21319273   PMID:21344488   PMID:21364740  
PMID:21371741   PMID:21383955   PMID:21415862   PMID:21424069   PMID:21461937   PMID:21492153   PMID:21501231   PMID:21504906   PMID:21536034   PMID:21549307   PMID:21605556   PMID:21628590  
PMID:21640107   PMID:21654808   PMID:21664290   PMID:21690293   PMID:21694464   PMID:21700221   PMID:21704031   PMID:21725088   PMID:21738398   PMID:21768287   PMID:21791603   PMID:21846465  
PMID:21855803   PMID:21856198   PMID:21858012   PMID:21873635   PMID:21875946   PMID:21880767   PMID:21930785   PMID:21935871   PMID:21952639   PMID:21967848   PMID:21978893   PMID:21988832  
PMID:21994455   PMID:21996408   PMID:22021614   PMID:22057681   PMID:22086303   PMID:22145905   PMID:22148433   PMID:22153967   PMID:22157815   PMID:22157819   PMID:22199292   PMID:22203964  
PMID:22232658   PMID:22238610   PMID:22268729   PMID:22293751   PMID:22303007   PMID:22304920   PMID:22334915   PMID:22362778   PMID:22381917   PMID:22383522   PMID:22387026   PMID:22393258  
PMID:22451935   PMID:22456510   PMID:22457066   PMID:22520514   PMID:22529391   PMID:22556262   PMID:22586102   PMID:22592530   PMID:22606318   PMID:22617335   PMID:22622474   PMID:22623772  
PMID:22634751   PMID:22681887   PMID:22692198   PMID:22704558   PMID:22705370   PMID:22759634   PMID:22763828   PMID:22810586   PMID:22846997   PMID:22863883   PMID:22894931   PMID:22898364  
PMID:22902626   PMID:22902628   PMID:22904075   PMID:22918591   PMID:22939629   PMID:22966418   PMID:22980979   PMID:22987070   PMID:22989887   PMID:23000965   PMID:23042605   PMID:23042607  
PMID:23101935   PMID:23139781   PMID:23152873   PMID:23223023   PMID:23248005   PMID:23277426   PMID:23317197   PMID:23337132   PMID:23345618   PMID:23364796   PMID:23388460   PMID:23443559  
PMID:23485469   PMID:23527218   PMID:23542172   PMID:23580141   PMID:23677613   PMID:23703321   PMID:23708667   PMID:23731732   PMID:23761444   PMID:23825390   PMID:23840062   PMID:23846616  
PMID:23939377   PMID:23963898   PMID:24012694   PMID:24022480   PMID:24061459   PMID:24115439   PMID:24141788   PMID:24200966   PMID:24267889   PMID:24283290   PMID:24337577   PMID:24379417  
PMID:24407433   PMID:24423875   PMID:24474685   PMID:24561620   PMID:24583282   PMID:24617039   PMID:24623722   PMID:24637615   PMID:24657165   PMID:24672041   PMID:24695737   PMID:24699724  
PMID:24710624   PMID:24711643   PMID:24728180   PMID:24768535   PMID:24852133   PMID:24911150   PMID:24939902   PMID:24958773   PMID:24962565   PMID:24999758   PMID:25013792   PMID:25036435  
PMID:25058453   PMID:25071155   PMID:25147182   PMID:25154416   PMID:25169136   PMID:25184665   PMID:25184681   PMID:25192599   PMID:25324306   PMID:25404403   PMID:25411249   PMID:25416956  
PMID:25435364   PMID:25437307   PMID:25502805   PMID:25614517   PMID:25670202   PMID:25675097   PMID:25692884   PMID:25733866   PMID:25762514   PMID:25766642   PMID:25798074   PMID:25825764  
PMID:25893307   PMID:25921289   PMID:25972089   PMID:26030842   PMID:26117423   PMID:26170230   PMID:26186194   PMID:26223641   PMID:26264872   PMID:26272819   PMID:26339416   PMID:26344197  
PMID:26350214   PMID:26377631   PMID:26408825   PMID:26450907   PMID:26485645   PMID:26496610   PMID:26499835   PMID:26508657   PMID:26527279   PMID:26549024   PMID:26557712   PMID:26641092  
PMID:26666832   PMID:26673319   PMID:26688547   PMID:26711499   PMID:26731993   PMID:26751069   PMID:26771714   PMID:26777405   PMID:26795561   PMID:26811472   PMID:26825464   PMID:26831064  
PMID:26903512   PMID:26972000   PMID:26988343   PMID:27025967   PMID:27084448   PMID:27107012   PMID:27114453   PMID:27146073   PMID:27248496   PMID:27342126   PMID:27377895   PMID:27407148  
PMID:27462432   PMID:27462463   PMID:27516012   PMID:27591049   PMID:27609421   PMID:27634302   PMID:27676213   PMID:27684187   PMID:27694619   PMID:27759041   PMID:27770570   PMID:27793507  
PMID:27871366   PMID:27906959   PMID:27916662   PMID:28071730   PMID:28073635   PMID:28157503   PMID:28177605   PMID:28180305   PMID:28191891   PMID:28192407   PMID:28199690   PMID:28302793  
PMID:28348081   PMID:28348485   PMID:28380382   PMID:28423618   PMID:28430587   PMID:28439008   PMID:28447756   PMID:28514442   PMID:28515154   PMID:28515276   PMID:28581483   PMID:28590137  
PMID:28611525   PMID:28718761   PMID:28746850   PMID:28777577   PMID:28803780   PMID:28814116   PMID:28831681   PMID:28886337   PMID:28924044   PMID:28934471   PMID:28951215   PMID:29019895  
PMID:29051491   PMID:29095607   PMID:29226655   PMID:29229926   PMID:29262658   PMID:29290612   PMID:29331416   PMID:29378950   PMID:29382432   PMID:29424068   PMID:29467282   PMID:29490077  
PMID:29507755   PMID:29510343   PMID:29598900   PMID:29604309   PMID:29753763   PMID:29845934   PMID:29875773   PMID:29892012   PMID:29937341   PMID:29955894   PMID:29991511   PMID:29997244  
PMID:30006506   PMID:30018425   PMID:30102405   PMID:30178842   PMID:30184152   PMID:30217970   PMID:30260704   PMID:30301766   PMID:30335157   PMID:30357346   PMID:30419336   PMID:30456385  
PMID:30463901   PMID:30530694   PMID:30554877   PMID:30563767   PMID:30590055   PMID:30619736   PMID:30623174   PMID:30647135   PMID:30696947   PMID:30700555   PMID:30705406   PMID:30779731  
PMID:30833792   PMID:30858175   PMID:30861164   PMID:30890647   PMID:30897015   PMID:30940648   PMID:30942439   PMID:30943414   PMID:30948266   PMID:30963698   PMID:31112565   PMID:31128028  
PMID:31134302   PMID:31160570   PMID:31180492   PMID:31235252   PMID:31257482   PMID:31298327   PMID:31467278   PMID:31492810   PMID:31515488   PMID:31550741   PMID:31586398   PMID:31607135  
PMID:31620119   PMID:31629712   PMID:31685992   PMID:31722399   PMID:31751430   PMID:31796584   PMID:31844045   PMID:31873223   PMID:31875566   PMID:31887036   PMID:31973093   PMID:31995728  
PMID:32082966   PMID:32092106   PMID:32203420   PMID:32276417   PMID:32296183   PMID:32311975   PMID:32314787   PMID:32416067   PMID:32466590   PMID:32481484   PMID:32701997   PMID:32780723  
PMID:32783654   PMID:32814343   PMID:32814904   PMID:32900933   PMID:33029857   PMID:33144569   PMID:33157085   PMID:33288556  


Genomics

Comparative Map Data
PCNA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl205,114,953 - 5,126,626 (-)EnsemblGRCh38hg38GRCh38
GRCh38205,114,953 - 5,126,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37205,095,599 - 5,107,268 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36205,043,599 - 5,055,268 (-)NCBINCBI36hg18NCBI36
Build 34205,043,598 - 5,048,647NCBI
Celera205,165,620 - 5,177,289 (-)NCBI
Cytogenetic Map20p12.3NCBI
HuRef205,049,534 - 5,061,197 (-)NCBIHuRef
CHM1_1205,096,983 - 5,108,646 (-)NCBICHM1_1
Pcna
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392132,091,206 - 132,095,100 (-)NCBIGRCm39mm39
GRCm39 Ensembl2132,091,082 - 132,095,234 (-)Ensembl
GRCm382132,249,286 - 132,253,180 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2132,249,162 - 132,253,314 (-)EnsemblGRCm38mm10GRCm38
MGSCv372132,075,022 - 132,078,916 (-)NCBIGRCm37mm9NCBIm37
MGSCv362131,940,727 - 131,944,621 (-)NCBImm8
Celera2133,472,471 - 133,476,365 (-)NCBICelera
Cytogenetic Map2F2NCBI
cM Map264.15NCBI
Pcna
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23119,499,039 - 119,502,911 (-)NCBI
Rnor_6.0 Ensembl3124,880,698 - 124,884,570 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03124,880,698 - 124,884,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03131,376,235 - 131,380,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43120,008,715 - 120,012,589 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13119,914,289 - 119,918,243 (-)NCBI
Celera3118,296,567 - 118,300,439 (-)NCBICelera
RH 3.4 Map31023.4RGD
Cytogenetic Map3q36NCBI
Pcna
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541515,744,601 - 15,749,673 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541515,744,601 - 15,748,910 (-)NCBIChiLan1.0ChiLan1.0
PCNA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1204,927,731 - 4,939,440 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl204,927,731 - 4,939,440 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0205,134,930 - 5,146,603 (-)NCBIMhudiblu_PPA_v0panPan3
PCNA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12416,478,774 - 16,485,992 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2416,478,769 - 16,484,992 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2416,301,671 - 16,308,866 (+)NCBI
ROS_Cfam_1.02416,892,157 - 16,899,336 (+)NCBI
UMICH_Zoey_3.12416,489,199 - 16,496,352 (+)NCBI
UNSW_CanFamBas_1.02416,596,221 - 16,603,283 (+)NCBI
UU_Cfam_GSD_1.02416,929,896 - 16,937,077 (+)NCBI
Pcna
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640165,334,861 - 165,339,851 (+)NCBI
SpeTri2.0NW_00493648513,766,221 - 13,771,215 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCNA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1714,125,814 - 14,185,276 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11714,137,746 - 14,142,584 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21715,127,978 - 15,132,806 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PCNA
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1232,936,600 - 32,953,635 (+)NCBI
ChlSab1.1 Ensembl232,948,196 - 32,953,991 (+)Ensembl
Pcna
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247416,143,584 - 6,148,055 (-)NCBI

Position Markers
RH68739  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,095,639 - 5,095,873UniSTSGRCh37
GRCh37X45,917,891 - 45,918,125UniSTSGRCh37
Build 36X45,802,835 - 45,803,069RGDNCBI36
Celera205,165,660 - 5,165,894UniSTS
CeleraX50,109,806 - 50,110,040RGD
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map20pter-p12UniSTS
HuRef205,049,574 - 5,049,808UniSTS
HuRefX43,632,455 - 43,632,689UniSTS
RH80338  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,095,651 - 5,095,853UniSTSGRCh37
GRCh37X45,917,903 - 45,918,105UniSTSGRCh37
Build 36X45,802,847 - 45,803,049RGDNCBI36
Celera205,165,672 - 5,165,874UniSTS
CeleraX50,109,818 - 50,110,020RGD
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map20pter-p12UniSTS
HuRef205,049,586 - 5,049,788UniSTS
HuRefX43,632,467 - 43,632,669UniSTS
G43531  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,095,648 - 5,095,854UniSTSGRCh37
GRCh37X45,917,900 - 45,918,106UniSTSGRCh37
Build 36X45,802,844 - 45,803,050RGDNCBI36
Celera205,165,669 - 5,165,875UniSTS
CeleraX50,109,815 - 50,110,021RGD
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map20pter-p12UniSTS
HuRef205,049,583 - 5,049,789UniSTS
HuRefX43,632,464 - 43,632,670UniSTS
GDB:450240  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,095,939 - 5,096,179UniSTSGRCh37
GRCh37X45,918,191 - 45,918,345UniSTSGRCh37
Build 36X45,803,135 - 45,803,289RGDNCBI36
Celera205,165,960 - 5,166,200UniSTS
CeleraX50,110,106 - 50,110,260RGD
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map20pter-p12UniSTS
HuRef205,049,874 - 5,050,114UniSTS
HuRefX43,632,755 - 43,632,909UniSTS
PMC134733P7  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,100,421 - 5,100,671UniSTSGRCh37
Build 36205,048,421 - 5,048,671RGDNCBI36
Celera205,170,442 - 5,170,692RGD
Cytogenetic Map20pter-p12UniSTS
HuRef205,054,355 - 5,054,605UniSTS
RH78927  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,095,652 - 5,095,888UniSTSGRCh37
GRCh37X45,917,904 - 45,918,140UniSTSGRCh37
Build 36X45,802,848 - 45,803,084RGDNCBI36
CeleraX50,109,819 - 50,110,055RGD
Celera205,165,673 - 5,165,909UniSTS
Cytogenetic Map20pter-p12UniSTS
Cytogenetic MapXp11.3UniSTS
HuRefX43,632,468 - 43,632,704UniSTS
HuRef205,049,587 - 5,049,823UniSTS
GeneMap99-GB4 RH Map2028.85UniSTS
NCBI RH Map2040.4UniSTS
STS-M15796  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37205,095,849 - 5,096,129UniSTSGRCh37
GRCh37X45,918,101 - 45,918,295UniSTSGRCh37
Build 36X45,803,045 - 45,803,239RGDNCBI36
CeleraX50,110,016 - 50,110,210RGD
Celera205,165,870 - 5,166,150UniSTS
Cytogenetic Map20pter-p12UniSTS
Cytogenetic MapXp11.3UniSTS
HuRefX43,632,665 - 43,632,859UniSTS
HuRef205,049,784 - 5,050,064UniSTS
GeneMap99-GB4 RH MapX135.51UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR124-2hsa-miR-124-3pTarbaseexternal_infoMicroarrayNEGATIVE
MIR124-2hsa-miR-124-3pTarbaseexternal_infoProteomicsPOSITIVE
MIR24-2hsa-miR-24-3pMirtarbaseexternal_infoReporter assay;Western blot;qRT-PCRFunctional MTI19748357
MIR24-1hsa-miR-24-3pMirtarbaseexternal_infoReporter assay;Western blot;qRT-PCRFunctional MTI19748357

Predicted Target Of
Summary Value
Count of predictions:237
Count of miRNA genes:106
Interacting mature miRNAs:107
Transcripts:ENST00000379143, ENST00000379160
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 20 2 2 148 2 5 1 3 2 41 30 2
Medium 2406 2664 1705 605 1670 447 4304 2013 3494 406 1407 1577 169 1204 2742 4
Low 6 320 16 15 130 15 46 179 211 10 1 46
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_047066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_182649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF527838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL121924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG612192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU626265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB990423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR536501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000379143   ⟹   ENSP00000368438
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl205,114,953 - 5,119,958 (-)Ensembl
RefSeq Acc Id: ENST00000379160   ⟹   ENSP00000368458
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl205,114,953 - 5,126,626 (-)Ensembl
RefSeq Acc Id: NM_002592   ⟹   NP_002583
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38205,114,953 - 5,126,622 (-)NCBI
GRCh37205,095,599 - 5,107,268 (-)ENTREZGENE
Build 36205,043,599 - 5,055,268 (-)NCBI Archive
HuRef205,049,534 - 5,061,197 (-)ENTREZGENE
CHM1_1205,096,983 - 5,108,646 (-)NCBI
Sequence:
RefSeq Acc Id: NM_182649   ⟹   NP_872590
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38205,114,953 - 5,119,958 (-)NCBI
GRCh37205,095,599 - 5,107,268 (-)ENTREZGENE
Build 36205,043,599 - 5,048,647 (-)NCBI Archive
HuRef205,049,534 - 5,061,197 (-)ENTREZGENE
CHM1_1205,096,983 - 5,102,031 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002583   ⟸   NM_002592
- UniProtKB: P12004 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_872590   ⟸   NM_182649
- UniProtKB: P12004 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000368438   ⟸   ENST00000379143
RefSeq Acc Id: ENSP00000368458   ⟸   ENST00000379160
Protein Domains
PCNA_C   PCNA_N

Promoters
RGD ID:6798893
Promoter ID:HG_KWN:38489
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000404149,   OTTHUMT00000077851
Position:
Human AssemblyChrPosition (strand)Source
Build 36205,048,349 - 5,048,849 (-)MPROMDB
RGD ID:6853402
Promoter ID:EP74526
Type:initiation region
Name:HS_PCNA
Description:Proliferating cell nuclear antigen.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 36205,048,604 - 5,048,664EPD
RGD ID:6798891
Promoter ID:HG_KWN:38492
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000077852,   OTTHUMT00000077855,   OTTHUMT00000077856,   OTTHUMT00000077857,   OTTHUMT00000077858,   UC002WLR.1,   UC002WLU.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36205,055,126 - 5,056,287 (-)MPROMDB
RGD ID:13206301
Promoter ID:EPDNEW_H26732
Type:initiation region
Name:PCNA_1
Description:proliferating cell nuclear antigen
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26734  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38205,119,955 - 5,120,015EPDNEW
RGD ID:13206307
Promoter ID:EPDNEW_H26734
Type:initiation region
Name:PCNA_2
Description:proliferating cell nuclear antigen
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26732  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38205,126,592 - 5,126,652EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_182649.2(PCNA):c.683G>T (p.Ser228Ile) single nucleotide variant Ataxia-telangiectasia-like disorder 2 [RCV000132551] Chr20:5115472 [GRCh38]
Chr20:5096118 [GRCh37]
Chr20:20p12.3
pathogenic|uncertain significance
GRCh38/hg38 20p13-11.21(chr20:89939-25697564)x3 copy number gain See cases [RCV000051227] Chr20:89939..25697564 [GRCh38]
Chr20:70580..25678200 [GRCh37]
Chr20:18580..25626200 [NCBI36]
Chr20:20p13-11.21
pathogenic
GRCh38/hg38 20p13-11.23(chr20:89939-19146279)x3 copy number gain See cases [RCV000051041] Chr20:89939..19146279 [GRCh38]
Chr20:70580..19126923 [GRCh37]
Chr20:18580..19074923 [NCBI36]
Chr20:20p13-11.23
pathogenic
GRCh38/hg38 20p13-12.3(chr20:5030412-5435054)x3 copy number gain See cases [RCV000052760] Chr20:5030412..5435054 [GRCh38]
Chr20:5011058..5415700 [GRCh37]
Chr20:4959058..5363700 [NCBI36]
Chr20:20p13-12.3
uncertain significance
GRCh38/hg38 20p13-11.23(chr20:89939-19071495)x3 copy number gain See cases [RCV000052995] Chr20:89939..19071495 [GRCh38]
Chr20:70580..19052139 [GRCh37]
Chr20:18580..19000139 [NCBI36]
Chr20:20p13-11.23
pathogenic
GRCh38/hg38 20p13-11.22(chr20:89939-21787252)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052996]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052996]|See cases [RCV000052996] Chr20:89939..21787252 [GRCh38]
Chr20:70580..21767890 [GRCh37]
Chr20:18580..21715890 [NCBI36]
Chr20:20p13-11.22
pathogenic
GRCh38/hg38 20p13-12.1(chr20:89939-14818511)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052997]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052997]|See cases [RCV000052997] Chr20:89939..14818511 [GRCh38]
Chr20:70580..14799157 [GRCh37]
Chr20:18580..14747157 [NCBI36]
Chr20:20p13-12.1
pathogenic
NM_002592.2(PCNA):c.216C>T (p.Leu72=) single nucleotide variant Malignant melanoma [RCV000072698] Chr20:5119583 [GRCh38]
Chr20:5100229 [GRCh37]
Chr20:5048229 [NCBI36]
Chr20:20p12.3
not provided
GRCh38/hg38 20p13-q11.1(chr20:80106-30227427)x3 copy number gain See cases [RCV000133996] Chr20:80106..30227427 [GRCh38]
Chr20:60747..29462103 [GRCh37]
Chr20:8747..28075764 [NCBI36]
Chr20:20p13-q11.1
pathogenic
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33
pathogenic
GRCh38/hg38 20p13-12.3(chr20:4343033-6911730)x1 copy number loss See cases [RCV000137695] Chr20:4343033..6911730 [GRCh38]
Chr20:4323680..6892377 [GRCh37]
Chr20:4271680..6840377 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-12.3(chr20:5039774-5645855)x3 copy number gain See cases [RCV000137853] Chr20:5039774..5645855 [GRCh38]
Chr20:5020420..5626501 [GRCh37]
Chr20:4968420..5574501 [NCBI36]
Chr20:20p13-12.3
uncertain significance
GRCh38/hg38 20p13-12.1(chr20:80106-13029401)x3 copy number gain See cases [RCV000138677] Chr20:80106..13029401 [GRCh38]
Chr20:60747..13010049 [GRCh37]
Chr20:8747..12958049 [NCBI36]
Chr20:20p13-12.1
pathogenic
GRCh38/hg38 20p13-12.3(chr20:80093-6386012)x3 copy number gain See cases [RCV000139597] Chr20:80093..6386012 [GRCh38]
Chr20:60734..6366659 [GRCh37]
Chr20:8734..6314659 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-12.3(chr20:4926195-5543771)x3 copy number gain See cases [RCV000139625] Chr20:4926195..5543771 [GRCh38]
Chr20:4906841..5524417 [GRCh37]
Chr20:4854841..5472417 [NCBI36]
Chr20:20p13-12.3
uncertain significance
GRCh38/hg38 20p13-12.3(chr20:84402-6159078)x3 copy number gain See cases [RCV000141348] Chr20:84402..6159078 [GRCh38]
Chr20:65043..6139725 [GRCh37]
Chr20:13043..6087725 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-11.1(chr20:80927-26324843)x3 copy number gain See cases [RCV000142017] Chr20:80927..26324843 [GRCh38]
Chr20:61568..26305479 [GRCh37]
Chr20:9568..26253479 [NCBI36]
Chr20:20p13-11.1
pathogenic
GRCh38/hg38 20p13-12.3(chr20:80927-5447679)x3 copy number gain See cases [RCV000142285] Chr20:80927..5447679 [GRCh38]
Chr20:61568..5428325 [GRCh37]
Chr20:9568..5376325 [NCBI36]
Chr20:20p13-12.3
uncertain significance
GRCh38/hg38 20p13-12.3(chr20:1269303-8626911)x3 copy number gain See cases [RCV000142917] Chr20:1269303..8626911 [GRCh38]
Chr20:1249947..8607558 [GRCh37]
Chr20:1197947..8555558 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-11.23(chr20:80928-18688031)x3 copy number gain See cases [RCV000143426] Chr20:80928..18688031 [GRCh38]
Chr20:61569..18668675 [GRCh37]
Chr20:9569..18616675 [NCBI36]
Chr20:20p13-11.23
pathogenic
GRCh37/hg19 20p13-12.3(chr20:121521-5564937)x3 copy number gain See cases [RCV000239772] Chr20:121521..5564937 [GRCh37]
Chr20:20p13-12.3
pathogenic
GRCh37/hg19 20p13-11.1(chr20:80198-26075841)x3 copy number gain See cases [RCV000239954] Chr20:80198..26075841 [GRCh37]
Chr20:20p13-11.1
pathogenic
GRCh37/hg19 20p13-12.1(chr20:4392930-12667768)x1 copy number loss See cases [RCV000446718] Chr20:4392930..12667768 [GRCh37]
Chr20:20p13-12.1
pathogenic
GRCh37/hg19 20p13-q11.21(chr20:80198-26208081)x3 copy number gain not provided [RCV000487461] Chr20:80198..26208081 [GRCh37]
Chr20:20p13-q11.21
pathogenic
GRCh37/hg19 20p13-12.3(chr20:213423-5483406)x3 copy number gain See cases [RCV000510531] Chr20:213423..5483406 [GRCh37]
Chr20:20p13-12.3
uncertain significance
GRCh37/hg19 20p13-12.3(chr20:2463101-8185680)x1 copy number loss See cases [RCV000511897] Chr20:2463101..8185680 [GRCh37]
Chr20:20p13-12.3
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-12.2(chr20:61568-10486106)x3 copy number gain See cases [RCV000512556] Chr20:61568..10486106 [GRCh37]
Chr20:20p13-12.2
likely pathogenic
GRCh37/hg19 20p13-12.1(chr20:3092739-17091453)x1 copy number loss not provided [RCV000684134] Chr20:3092739..17091453 [GRCh37]
Chr20:20p13-12.1
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62948788)x3 copy number gain not provided [RCV000741058] Chr20:63244..62948788 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62961294)x3 copy number gain not provided [RCV000741059] Chr20:63244..62961294 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62912463)x3 copy number gain not provided [RCV000741057] Chr20:63244..62912463 [GRCh37]
Chr20:20p13-q13.33
pathogenic
NM_182649.2(PCNA):c.261C>A (p.Ile87=) single nucleotide variant not provided [RCV000982732] Chr20:5118827 [GRCh38]
Chr20:5099473 [GRCh37]
Chr20:20p12.3
likely benign
NM_182649.2(PCNA):c.645T>C (p.Phe215=) single nucleotide variant not provided [RCV000926041] Chr20:5115510 [GRCh38]
Chr20:5096156 [GRCh37]
Chr20:20p12.3
likely benign
NM_182649.2(PCNA):c.235C>T (p.Leu79=) single nucleotide variant not provided [RCV000982777] Chr20:5118853 [GRCh38]
Chr20:5099499 [GRCh37]
Chr20:20p12.3
likely benign
NM_182649.2(PCNA):c.42G>A (p.Lys14=) single nucleotide variant not provided [RCV000976068] Chr20:5119757 [GRCh38]
Chr20:5100403 [GRCh37]
Chr20:20p12.3
likely benign
NM_182649.2(PCNA):c.726G>A (p.Ala242=) single nucleotide variant not provided [RCV000882941] Chr20:5115343 [GRCh38]
Chr20:5095989 [GRCh37]
Chr20:20p12.3
benign
NM_182649.2(PCNA):c.702C>G (p.Pro234=) single nucleotide variant not provided [RCV000968767] Chr20:5115453 [GRCh38]
Chr20:5096099 [GRCh37]
Chr20:20p12.3
benign
NM_182649.2(PCNA):c.33C>T (p.Ile11=) single nucleotide variant not provided [RCV000925801] Chr20:5119766 [GRCh38]
Chr20:5100412 [GRCh37]
Chr20:20p12.3
likely benign
NM_182649.2(PCNA):c.443G>C (p.Cys148Ser) single nucleotide variant Ataxia-telangiectasia-like disorder 2 [RCV000990278] Chr20:5117609 [GRCh38]
Chr20:5098255 [GRCh37]
Chr20:20p12.3
likely pathogenic
NM_182649.2(PCNA):c.612A>G (p.Gln204=) single nucleotide variant not provided [RCV000931181] Chr20:5115543 [GRCh38]
Chr20:5096189 [GRCh37]
Chr20:20p12.3
likely benign
GRCh37/hg19 20p13-11.1(chr20:61568-26305479)x3 copy number gain not provided [RCV001007068] Chr20:61568..26305479 [GRCh37]
Chr20:20p13-11.1
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8729 AgrOrtholog
COSMIC PCNA COSMIC
Ensembl Genes ENSG00000132646 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000368438 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000368458 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000379143 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000379160 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000132646 GTEx
HGNC ID HGNC:8729 ENTREZGENE
Human Proteome Map PCNA Human Proteome Map
InterPro Pr_cel_nuc_antig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pr_cel_nuc_antig_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pr_cel_nuc_antig_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pr_cel_nuc_antig_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5111 UniProtKB/Swiss-Prot
NCBI Gene 5111 ENTREZGENE
OMIM 176740 OMIM
  615919 OMIM
Pfam PCNA_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PCNA_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA263 PharmGKB
PRINTS PCNACYCLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PCNA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PCNA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs pcna UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P12004 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6FHF5_HUMAN UniProtKB/TrEMBL
  Q6FI35_HUMAN UniProtKB/TrEMBL
  Q7Z6A0_HUMAN UniProtKB/TrEMBL
  Q7Z6A1_HUMAN UniProtKB/TrEMBL
  Q7Z6A2_HUMAN UniProtKB/TrEMBL
  Q7Z6A3_HUMAN UniProtKB/TrEMBL
UniProt Secondary B2R897 UniProtKB/Swiss-Prot
  D3DW02 UniProtKB/Swiss-Prot