Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rfc1 (replication factor C subunit 1) Rattus norvegicus
Symbol: Rfc1
Name: replication factor C subunit 1
RGD ID: 620619
Description: Exhibits double-stranded DNA binding activity; protein domain specific binding activity; and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Localizes to cytoplasm; nucleolus; and protein-containing complex. Orthologous to human RFC1 (replication factor C subunit 1); PARTICIPATES IN FasL mediated signaling pathway; mismatch repair pathway; nucleotide excision repair pathway; INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Recc1; replication factor C; replication factor C (activator 1) 1; replication factor C 1
Homo sapiens (human) : RFC1 (replication factor C subunit 1)  HGNC  Alliance
Mus musculus (house mouse) : Rfc1 (replication factor C (activator 1) 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfc1 (replication factor C subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RFC1 (replication factor C subunit 1)
Canis lupus familiaris (dog) : RFC1 (replication factor C subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfc1 (replication factor C subunit 1)
Sus scrofa (pig) : RFC1 (replication factor C subunit 1)
Chlorocebus sabaeus (African green monkey) : RFC1 (replication factor C subunit 1)
Heterocephalus glaber (naked mole-rat) : Rfc1 (replication factor C subunit 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01444,627,528 - 44,702,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,580,216 - 44,702,203 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,441,565 - 44,516,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,665,717 - 45,741,391 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11445,668,107 - 45,730,578 (+)NCBI
Celera1442,109,684 - 42,184,882 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Rfc1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620619
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.