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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732094
Species: Homo sapiens
RGD Object: Gene
Symbol: PCNA
Name: proliferating cell nuclear antigen
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PCNAincreases expressionISOPcna (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of PCNA mRNA; Thioacetamide results in increased expression of PCNA proteinPMID:21251946 PMID:34492290
PCNAincreases expressionISOPcna (Mus musculus)6480464CTDThioacetamide results in increased expression of PCNA proteinPMID:16511523
PCNAmultiple interactionsISOPcna (Rattus norvegicus)6480464CTDThioctic Acid inhibits the reaction [Thioacetamide results in increased expression of PCNA protein]PMID:21251946
PCNAmultiple interactionsISOPcna (Mus musculus)6480464CTDPOMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of PCNA protein]PMID:16511523
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