Papss2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2)

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Gene: Papss2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2) Rattus norvegicus

Analyze

Symbol:

Papss2

Name:

3'-phosphoadenosine 5'-phosphosulfate synthase 2

RGD ID:

1307012

Description:

Predicted to enable adenylylsulfate kinase activity and sulfate adenylyltransferase (ATP) activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; hormone metabolic process; and sulfate assimilation. Predicted to act upstream of or within blood coagulation and bone development. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Orthologous to human PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2); PARTICIPATES IN sulfite oxidase deficiency pathway; purine metabolic pathway; selenoamino acid metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; LOC294103; MGC189455

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	230,454,314 - 230,539,332 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	230,454,426 - 230,539,331 (+)	Ensembl
Rnor_6.0	1	251,145,264 - 251,230,716 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	251,145,253 - 251,230,715 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	258,376,054 - 258,461,337 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	236,592,414 - 236,677,379 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	236,796,239 - 236,839,791 (+)	NCBI
Celera	1	227,570,258 - 227,654,408 (+)	NCBI		Celera
Cytogenetic Map	1	q52	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

brachyolmia (ISO)

juvenile polyposis syndrome (ISO)

PTEN hamartoma tumor syndrome (ISO)

spondyloepimetaphyseal dysplasia, Pakistani type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

4-octylphenol (ISO)

7,12-dimethyltetraphene (EXP)

8-Br-cAMP (ISO)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

Aroclor 1254 (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

avobenzone (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

Benzo[ghi]perylene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butane-2,3-dione (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

cetrorelix (ISO)

chlordecone (ISO)

chloroprene (ISO)

cholic acid (ISO)

choline (ISO)

clofibrate (EXP,ISO)

clofibric acid (EXP)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cyproconazole (ISO)

decabromodiphenyl ether (ISO)

desogestrel (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (EXP)

Diisodecyl phthalate (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

epoxiconazole (ISO)

ethanol (ISO)

etoposide (ISO)

flurbiprofen (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

griseofulvin (ISO)

indole-3-methanol (EXP)

isoprenaline (ISO)

ivermectin (ISO)

L-methionine (ISO)

lead diacetate (EXP)

methyltestosterone (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

nimesulide (EXP)

paracetamol (ISO)

paraquat (EXP)

pentane-2,3-dione (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

phorbol 13-acetate 12-myristate (ISO)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

propiconazole (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP)

sodium dichromate (EXP)

Soman (EXP)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone enanthate (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triadimefon (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

triphenyl phosphate (EXP)

tris(2-butoxyethyl) phosphate (ISO)

troglitazone (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

3'-phosphoadenosine 5'-phosphosulfate biosynthetic process (IBA,ISO)

biological_process (ND)

blood coagulation (ISO)

bone development (ISO)

hormone metabolic process (ISO)

sulfate assimilation (IBA,IEA,ISO)

Cellular Component

cellular_component (ND)

cytosol (TAS)

Molecular Function

adenylylsulfate kinase activity (IBA,ISO)

ATP binding (IEA)

molecular_function (ND)

protein binding (ISO)

selenate adenylyltransferase (ATP) activity (TAS)

sulfate adenylyltransferase (ATP) activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

purine metabolic pathway (IEA)

selenoamino acid metabolic pathway (IEA)

sulfite oxidase deficiency pathway (ISO)

sulfur metabolic pathway (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	MGD data from the GO Consortium
4.	OMIM Disease Annotation Pipeline
5.	Pipeline to import KEGG annotations from KEGG into RGD
6.	Pipeline to import SMPDB annotations from SMPDB into RGD
7.	RGD automated data pipeline
8.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	RGD automated import pipeline for gene-chemical interactions
10.	RGD comprehensive gene curation

Additional References at PubMed

PMID:624676	PMID:8835524	PMID:10559207	PMID:12477932

Genomics

Comparative Map Data

Papss2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	230,454,314 - 230,539,332 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	230,454,426 - 230,539,331 (+)	Ensembl
Rnor_6.0	1	251,145,264 - 251,230,716 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	251,145,253 - 251,230,715 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	258,376,054 - 258,461,337 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	236,592,414 - 236,677,379 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	236,796,239 - 236,839,791 (+)	NCBI
Celera	1	227,570,258 - 227,654,408 (+)	NCBI		Celera
Cytogenetic Map	1	q52	NCBI

PAPSS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	87,659,878 - 87,747,705 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	10	87,659,613 - 87,747,705 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	89,419,635 - 89,507,462 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	89,409,456 - 89,497,442 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	10	89,409,607 - 89,496,142	NCBI
Celera	10	83,166,000 - 83,253,966 (+)	NCBI
Cytogenetic Map	10	q23.2-q23.31	NCBI
HuRef	10	83,054,540 - 83,142,617 (+)	NCBI		HuRef
CHM1_1	10	89,701,783 - 89,789,765 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	88,543,727 - 88,631,613 (+)	NCBI

Papss2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	32,573,072 - 32,644,587 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	19	32,573,190 - 32,644,587 (+)	Ensembl
GRCm38	19	32,595,669 - 32,667,187 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	32,595,790 - 32,667,187 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	32,694,495 - 32,741,677 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	19	32,686,002 - 32,733,184 (+)	NCBI			mm8
Celera	19	33,402,870 - 33,450,031 (+)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	27.46	NCBI

Papss2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	5,187,952 - 5,258,955 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	5,186,232 - 5,259,080 (-)	NCBI	ChiLan1.0	ChiLan1.0

PAPSS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	10	87,890,631 - 87,977,839 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	87,890,631 - 87,977,839 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	10	84,383,936 - 84,471,745 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

PAPSS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	37,725,205 - 37,745,103 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	37,725,616 - 37,743,928 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	37,579,442 - 37,627,983 (+)	NCBI
ROS_Cfam_1.0	26	39,227,070 - 39,275,831 (+)	NCBI
UMICH_Zoey_3.1	26	37,134,164 - 37,182,464 (+)	NCBI
UNSW_CanFamBas_1.0	26	36,715,608 - 36,764,348 (+)	NCBI
UU_Cfam_GSD_1.0	26	37,955,064 - 38,003,810 (+)	NCBI

Papss2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	77,276,657 - 77,356,538 (+)	NCBI
SpeTri2.0	NW_004936735	1,437,108 - 1,516,382 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PAPSS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	99,685,578 - 99,808,389 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	99,718,299 - 99,816,346 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	108,701,055 - 108,789,588 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PAPSS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	81,102,477 - 81,191,951 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	9	81,102,520 - 81,190,230 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666048	41,763,494 - 41,853,076 (+)	NCBI	Vero_WHO_p1.0

Papss2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624791	13,789,584 - 13,866,543 (+)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624791	13,789,539 - 13,866,551 (+)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

D1Rat446

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	230,496,217 - 230,496,355 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	251,187,687 - 251,187,824	NCBI	Rnor6.0
Rnor_5.0	1	258,418,499 - 258,418,636	UniSTS	Rnor5.0
RGSC_v3.4	1	236,634,422 - 236,634,559	UniSTS	RGSC3.4
RGSC_v3.4	1	236,634,422 - 236,634,559	RGD	RGSC3.4
RGSC_v3.1	1	236,798,045 - 236,798,659	RGD
Celera	1	227,611,687 - 227,611,824	UniSTS
RH 2.0 Map	2	419.8	RGD
SHRSP x BN Map	1	127.73	RGD
Cytogenetic Map	1	q52	UniSTS

AU047720

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	230,529,290 - 230,529,505 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	251,220,677 - 251,220,891	NCBI	Rnor6.0
Rnor_5.0	1	258,451,298 - 258,451,512	UniSTS	Rnor5.0
RGSC_v3.4	1	236,667,340 - 236,667,554	UniSTS	RGSC3.4
Celera	1	227,644,369 - 227,644,583	UniSTS
Cytogenetic Map	1	q52	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	183970203	243914901	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	183970203	243914901	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	185356336	231689108	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	191019702	246062233	Rat
10059590	Kidm44	Kidney mass QTL 44	3.42	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	191033875	236033875	Rat
1358191	Ept10	Estrogen-induced pituitary tumorigenesis QTL 10	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	192825253	243914732	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	193113876	238113876	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	196248093	241248093	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	0.00000081	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	196248093	241248093	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	197670404	242670404	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	197697768	238755659	Rat
2302375	Bw83	Body weight QTL 83	4.87	0.0002	body mass (VT:0001259)	body weight (CMO:0000012)	1	197697768	242697768	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	197814409	242814409	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	197814409	242814409	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	197814409	242814409	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	201554356	246554356	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	201554356	246554356	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	201554356	246554356	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	201554356	246554356	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	201554356	246554356	Rat
10059587	Bw173	Body weight QTL 173	3.23	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	1	202069611	247069611	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	203995416	244113296	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	206081677	251081677	Rat
1357399	Bw45	Body weight QTL 45	3.05		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	1	206329708	251329708	Rat
1357404	Bw42	Body weight QTL 42	4.49	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	206329708	251329708	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	210702053	240947965	Rat
1358890	Bp259	Blood pressure QTL 259	3.06		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	210702053	260522016	Rat
2292216	Bw80	Body weight QTL 80	3.23	0.0019	body mass (VT:0001259)	body weight (CMO:0000012)	1	213533809	243914901	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	213707201	252085212	Rat
734768	Niddm59	Non-insulin dependent diabetes mellitus QTL 59			body mass (VT:0001259)	body weight (CMO:0000012)	1	213843987	258843987	Rat
61455	Niddm7	Non-insulin dependent diabetes mellitus QTL 7	5.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	214537555	238757011	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	214647894	259647894	Rat
1549910	Bw54	Body weight QTL 54		0.05	body mass (VT:0001259)	body weight (CMO:0000012)	1	214647894	259647894	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	216255568	260522016	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	216255568	260522016	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	218748008	257976495	Rat
61400	Niddm1	Non-insulin dependent diabetes mellitus QTL 1	11		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	218753689	245907899	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	218753816	256448513	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	221264111	259647894	Rat
10053715	Scort24	Serum corticosterone level QTL 24	2.13	0.0088	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	221414816	260522016	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	222363780	260522016	Rat
1600392	Bw123	Body weight QTL 123		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	223201027	260522016	Rat
2293700	Bmd27	Bone mineral density QTL 27	6.6	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	224054293	243747962	Rat
2293701	Bmd34	Bone mineral density QTL 34	8.3	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	1	224054293	243747962	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	224054293	260122809	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	224054293	260122809	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	224569538	260122809	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	225126575	260522016	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	228581588	259647894	Rat
2316896	Gluco57	Glucose level QTL 57	7.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	228985440	245907899	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	226
Count of miRNA genes:	142
Interacting mature miRNAs:	180
Transcripts:	ENSRNOT00000014979
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2		33	27	13	27			4	27	19	11
Low	1	43	24	14	6	14	8	11	68	8	22		8
Below cutoff									2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC169061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000014979 ⟹ ENSRNOP00000014979

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	230,454,426 - 230,539,331 (+)	Ensembl
Rnor_6.0 Ensembl	1	251,145,363 - 251,230,715 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083555 ⟹ ENSRNOP00000074860

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	230,454,426 - 230,539,331 (+)	Ensembl
Rnor_6.0 Ensembl	1	251,145,253 - 251,229,303 (+)	Ensembl

RefSeq Acc Id:

NM_001106375 ⟹ NP_001099845

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	230,454,426 - 230,539,332 (+)	NCBI
Rnor_6.0	1	251,145,363 - 251,230,716 (+)	NCBI
Rnor_5.0	1	258,376,054 - 258,461,337 (+)	NCBI
RGSC_v3.4	1	236,592,414 - 236,677,379 (+)	RGD
Celera	1	227,570,258 - 227,654,408 (+)	RGD

Sequence:

show sequence

TGCACCCTGGACCCGGGCTCCGTCCCAGCCGCAGCATGTCGGAGATCAAGAAGCAGAAGACGGA
CCAGCAAAAATCCACCAATGTGGTCTACCAGGCCCATCATGTGAGCAGGAACAAGAGAGGACAG
GTGGTTGGAACCAGAGGAGGATTCAGAGGATGTACCGTGTGGCTAACAGGTCTCTCCGGCGCTG
GAAAAACAACCATAAGCTTCGCTTTGGAGGAGTACCTTGTGTCTCATGCCATCCCGTGTTACTC
CCTGGATGGAGACAATGTCCGTCATGGCCTTAACAAGAACCTGGGATTCTCTGCCGGGGACCGA
GAAGAGAATATCCGTCGAATTGCAGAGGTGGCCAAGCTCTTTGCTGATGCTGGCCTAGTGTGCA
TTACCAGTTTTATTTCTCCATTTGCAAAGGATCGTGAGAATGCCCGCAAAATCCACGAATCAGC
AGGACTCCCCTTCTTTGAGATCTTTGTAGATGCACCTTTAAATATCTGTGAAAGCCGAGATGTA
AAAGGACTCTACAAACGCGCTCGGGCAGGAGAGATTAAAGGGTTTACAGGCATCGATTCCAATT
ATGAGAAACCCGAGACTCCAGAGTGTGTGCTGAAGACCAACTTGTCCTCAGTGAGCGACTGTGT
GCAGCAGGTGGTGGAGCTTCTGCAAGAGCAGAGCATTGTTCCCCACACCACCATCAAAGGCATC
CATGAACTCTTTGTGCCGGAAAACAAAATTGATCAAATCCGAGCTGAGTTAGAGACTCTCCCAT
CACTACCAATTACCAAGCTGGATCTGCAGTGGGTGCAGATTCTGAGCGAAGGCTGGGCCACTCC
GCTCAAAGGCTTTATGAGGGAAAAGGAGTACTTGCAAACTCTGCACTTCGACACCCTACTGGAC
GATGGAGTCATCAACATGAGCATTCCCATCGTACTGCCTGTTTCTGGGGATGACAAGGCACGGC
TCGAAGGCTGCAGCAAGTTTGCCTTGATGTACGAAGGCCGGAGGGTAGCTCTCTTACAAGACCC
TGAATTCTATGAGCATAGGAAAGAGGAGCGTTGTTCTCGTGTGTGGGGAACAGCCAGTGCAAAA
CACCCCCATATCAAAATGGTGATGGAAGGTGGGGACTGGCTTGTTGGTGGAGACCTTCAGGTGC
TAGAGAGAATACGGTGGAATGATGGGCTGGACCAGTACCGCCTGACGCCTCTAGAGCTCAAACA
GAAGTGTAAAGACATGGATGCTGATGCCGTGTTTGCGTTCCAGTTACGCAATCCTGTCCACAAC
GGCCACGCTCTGCTGATGCAAGACACCCGGCGCAGGCTCCTGGAGAGGGGCTACAAGCACCCGG
TCCTCCTGCTGCACCCTCTCGGGGGCTGGACCAAGGACGATGACGTACCTCTCGACTGGAGGAT
GAAACAGCATGCGGCTGTGCTGGAGGAAGGGATCCTGGATCCCAAGTCGACTATTGTCGCCATC
TTCCCATCTCCTATGTTATACGCTGGGCCTACAGAGGTCCAGTGGCACTGCAGGTGCCGAATGA
TTGCAGGGGCCAATTTCTACATCGTGGGTAGGGATCCTGCAGGAATGCCTCACCCTGAGACAAA
GAAAGACCTATACGAACCTACCCATGGTGGTAAGGTCTTGAGCATGGCCCCTGGCCTCACCTCT
GTGGAAATCATTCCATTCCGAGTGGCTGCCTACAATAAAATTAAGAAGGCCATGGACTTTTATG
ATCCGGCAAGGCACGATGAGTTTGACTTCATCTCAGGAACTCGTATGAGGAAGCTCGCCCGGGA
AGGAGAAGATCCCCCAGATGGCTTCATGGCCCCCAAAGCATGGAAAGTGTTGACAGATTATTAC
AGGTCTCTGGAGAAGATCAACTAGGTGCTCCCGGCTCTGGTTTCTTTCTCAAGTGCTCTATGAC
GATTTTTTTCTATTTTTGTGATTAGCGGCTCTGTATCCAATTGCTTCTTGATGACTTTTTAAAG
TTAGTATTTTGCAATGAAGTAAAAAGTTGTGTCTATAATTTAAAACCAACTTCATTATGTCTAT
GAAACTCACACTGGAGACTAAGTCTTAGGTGAAAACATTGTTGTACATTCCAGAATGAAAGCAC
TTGTATACTACTTCATCTCAGCATATATGTCTCAGATTTCTTAAAAATGTGACTACATGTCTAG
CTGACTTGCCCAGGACAGAATCATACTTTCTGGCTTACTTTTGCCAGCCTGGAATTCTAATGTC
ACCAAACACACACACACACACACACACACACACACACACACACACACACACACACACACAGACA
CACACACACACACACACACACACACACACAGAGTCATCTTGAAGGAAATGTTTCATATCAGGAC
TTTTTACTTCGTGACTACACATGGCCTCACTGCCCAATGTATGAGATGAAGATGAATGAAACTG
GAAGGAAAATATGTGTGAAGATGCGAACTAAATCTTAAAGATGTCTGTAACGTACGTCTGCCAT
GAAAATAGAAAGAGACGTGCTAGTGGCCGTCTATGAATAGTAACTCCAGTGGGAAGGCACTTTT
CAAAAGCATGGTATGTATGCTTTGGTCAAAAGATTTCTCCCAGGGACTAAACCATCAGGGTTAC
ATTGTAGACTACTTTCCCCAGACTTGCTGTGGTCATAGTTATCTTAGAGGCACCTATTTGATCG
CTGTAGTCAAAACCAACCCACATACTAAACTAATGAGAAGCTAAAACCTGATTTCTGTAGAAAA
GATAAAGTCCAAACATCTTCATCCTAGATAAAATCTCCATTCTTCCATATCAGCTTTGAGAGCT
GCTGAGCACTGTAATACACCACACTGACATTAGCAAATACTCCTGACACTCAAAGGCTGCCCGG
ACTACCACCCTCCTAAGCTAGGTCCCTTCCTCCCCACAACACAGGAACAGGTTCTGATTCCTTG
AAGCTACTTAATGAAGCTCTCCTTGAGGATGCTAAAAGCAACCACCTTGGAGACAGAAGGTTCA
GGGCATCCTAAACTCTTGATGTTACAAGTTTCCAGAATGGACCTGTTCGACGTCCTTTGACGGT
TTATTTTCTAAGAGGGAATTTTGATATTTTATGCATGGTTCACTGTTGCCCAGGGATACGTAAA
AGAAAAAATACCTTTACATACAGGTGTCTTTGGAAGAGACCACAGACTGAAGAGAAACTGATTT
TTTTCATACTGCCACGTTTTTAGAATACTAGTAAGAGCTCTTTTGAGAGTAAGTTACATACCGT
GACCACAGCGAGTGAGTCTTCAACTGTTAGTGCCTGTGCTCACTTAGGCCGGAGTTACTCATTG
CTGCCTTTAAAACTGTGTGTTCACTGAAAACACGACAGGGCTGCAGTGCCTTACCAAATGGAGT
GAGATTCTAAAGACAGTAAAGTGCCTTTCTGCTCTAACAGTTGGTGTGACTGTTTCAGTGTCCC
GCTGATACTTGTTCTTCAATAAATCTCTCAAAGACCAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006231274 ⟹ XP_006231336

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	230,454,314 - 230,539,332 (+)	NCBI
Rnor_6.0	1	251,145,264 - 251,230,716 (+)	NCBI
Rnor_5.0	1	258,376,054 - 258,461,337 (+)	NCBI

Sequence:

show sequence

AGGAGAAGGGGGCCGGTCAAGGGAAGTGCGACGTGTCTGAGGAGCCTTTTTATACCTCCTTCCC
TGGAGCCGGGCAGCCACCGCCGCCATCCACGTCTCTGCACCCTGGACCCGGGCTCCGTCCCAGC
CGCAGCATGTCGGAGATCAAGAAGCAGAAGACGGACCAGCAAAAATCCACCAATGTGGTCTACC
AGGCCCATCATGTGAGCAGGAACAAGAGAGGACAGGTGGTTGGAACCAGAGGAGGATTCAGAGG
ATGTACCGTGTGGCTAACAGGTCTCTCCGGCGCTGGAAAAACAACCATAAGCTTCGCTTTGGAG
GAGTACCTTGTGTCTCATGCCATCCCGTGTTACTCCCTGGATGGAGACAATGTCCGTCATGGCC
TTAACAAGAACCTGGGATTCTCTGCCGGGGACCGAGAAGAGAATATCCGTCGAATTGCAGAGGT
GGCCAAGCTCTTTGCTGATGCTGGCCTAGTGTGCATTACCAGTTTTATTTCTCCATTTGCAAAG
GATCGTGAGAATGCCCGCAAAATCCACGAATCAGCAGGACTCCCCTTCTTTGAGATCTTTGTAG
ATGCACCTTTAAATATCTGTGAAAGCCGAGATGTAAAAGGACTCTACAAACGCGCTCGGGCAGG
AGAGATTAAAGGGTTTACAGGCATCGATTCCAATTATGAGAAACCCGAGACTCCAGAGTGTGTG
CTGAAGACCAACTTGTCCTCAGTGAGCGACTGTGTGCAGCAGGTGGTGGAGCTTCTGCAAGAGC
AGAGCATTGTTCCCCACACCACCATCAAAGGCATCCATGAACTCTTTGTGCCGGAAAACAAAAT
TGATCAAATCCGAGCTGAGTTAGAGACTCTCCCATCACTACCAATTACCAAGCTGGATCTGCAG
TGGGTGCAGATTCTGAGCGAAGGCTGGGCCACTCCGCTCAAAGGCTTTATGAGGGAAAAGGAGT
ACTTGCAAACTCTGCACTTCGACACCCTACTGGACGGCGTGATCCTCCGTGATGGAGTCATCAA
CATGAGCATTCCCATCGTACTGCCTGTTTCTGGGGATGACAAGGCACGGCTCGAAGGCTGCAGC
AAGTTTGCCTTGATGTACGAAGGCCGGAGGGTAGCTCTCTTACAAGACCCTGAATTCTATGAGC
ATAGGAAAGAGGAGCGTTGTTCTCGTGTGTGGGGAACAGCCAGTGCAAAACACCCCCATATCAA
AATGGTGATGGAAGGTGGGGACTGGCTTGTTGGTGGAGACCTTCAGGTGCTAGAGAGAATACGG
TGGAATGATGGGCTGGACCAGTACCGCCTGACGCCTCTAGAGCTCAAACAGAAGTGTAAAGACA
TGGATGCTGATGCCGTGTTTGCGTTCCAGTTACGCAATCCTGTCCACAACGGCCACGCTCTGCT
GATGCAAGACACCCGGCGCAGGCTCCTGGAGAGGGGCTACAAGCACCCGGTCCTCCTGCTGCAC
CCTCTCGGGGGCTGGACCAAGGACGATGACGTACCTCTCGACTGGAGGATGAAACAGCATGCGG
CTGTGCTGGAGGAAGGGATCCTGGATCCCAAGTCGACTATTGTCGCCATCTTCCCATCTCCTAT
GTTATACGCTGGGCCTACAGAGGTCCAGTGGCACTGCAGGTGCCGAATGATTGCAGGGGCCAAT
TTCTACATCGTGGGTAGGGATCCTGCAGGAATGCCTCACCCTGAGACAAAGAAAGACCTATACG
AACCTACCCATGGTGGTAAGGTCTTGAGCATGGCCCCTGGCCTCACCTCTGTGGAAATCATTCC
ATTCCGAGTGGCTGCCTACAATAAAATTAAGAAGGCCATGGACTTTTATGATCCGGCAAGGCAC
GATGAGTTTGACTTCATCTCAGGAACTCGTATGAGGAAGCTCGCCCGGGAAGGAGAAGATCCCC
CAGATGGCTTCATGGCCCCCAAAGCATGGAAAGTGTTGACAGATTATTACAGGTCTCTGGAGAA
GATCAACTAGGTGCTCCCGGCTCTGGTTTCTTTCTCAAGTGCTCTATGACGATTTTTTTCTATT
TTTGTGATTAGCGGCTCTGTATCCAATTGCTTCTTGATGACTTTTTAAAGTTAGTATTTTGCAA
TGAAGTAAAAAGTTGTGTCTATAATTTAAAACCAACTTCATTATGTCTATGAAACTCACACTGG
AGACTAAGTCTTAGGTGAAAACATTGTTGTACATTCCAGAATGAAAGCACTTGTATACTACTTC
ATCTCAGCATATATGTCTCAGATTTCTTAAAAATGTGACTACATGTCTAGCTGACTTGCCCAGG
ACAGAATCATACTTTCTGGCTTACTTTTGCCAGCCTGGAATTCTAATGTCACCAAACACACACA
CACACACACACACACACACACACACACACACACACACACACACAGACACACACACACACACACA
CACACACACACACAGAGTCATCTTGAAGGAAATGTTTCATATCAGGACTTTTTACTTCGTGACT
ACACATGGCCTCACTGCCCAATGTATGAGATGAAGATGAATGAAACTGGAAGGAAAATATGTGT
GAAGATGCGAACTAAATCTTAAAGATGTCTGTAACGTACGTCTGCCATGAAAATAGAAAGAGAC
GTGCTAGTGGCCGTCTATGAATAGTAACTCCAGTGGGAAGGCACTTTTCAAAAGCATGGTATGT
ATGCTTTGGTCAAAAGATTTCTCCCAGGGACTAAACCATCAGGGTTACATTGTAGACTACTTTC
CCCAGACTTGCTGTGGTCATAGTTATCTTAGAGGCACCTATTTGATCGCTGTAGTCAAAACCAA
CCCACATACTAAACTAATGAGAAGCTAAAACCTGATTTCTGTAGAAAAGATAAAGTCCAAACAT
CTTCATCCTAGATAAAATCTCCATTCTTCCATATCAGCTTTGAGAGCTGCTGAGCACTGTAATA
CACCACACTGACATTAGCAAATACTCCTGACACTCAAAGGCTGCCCGGACTACCACCCTCCTAA
GCTAGGTCCCTTCCTCCCCACAACACAGGAACAGGTTCTGATTCCTTGAAGCTACTTAATGAAG
CTCTCCTTGAGGATGCTAAAAGCAACCACCTTGGAGACAGAAGGTTCAGGGCATCCTAAACTCT
TGATGTTACAAGTTTCCAGAATGGACCTGTTCGACGTCCTTTGACGGTTTATTTTCTAAGAGGG
AATTTTGATATTTTATGCATGGTTCACTGTTGCCCAGGGATACGTAAAAGAAAAAATACCTTTA
CATACAGGTGTCTTTGGAAGAGACCACAGACTGAAGAGAAACTGATTTTTTTCATACTGCCACG
TTTTTAGAATACTAGTAAGAGCTCTTTTGAGAGTAAGTTACATACCGTGACCACAGCGAGTGAG
TCTTCAACTGTTAGTGCCTGTGCTCACTTAGGCCGGAGTTACTCATTGCTGCCTTTAAAACTGT
GTGTTCACTGAAAACACGACAGGGCTGCAGTGCCTTACCAAATGGAGTGAGATTCTAAAGACAG
TAAAGTGCCTTTCTGCTCTAACAGTTGGTGTGACTGTTTCAGTGTCCCGCTGATACTTGTTCTT
CAATAAATCTCTCAAAGACCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099845	(Get FASTA)	NCBI Sequence Viewer
	XP_006231336	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI69061	(Get FASTA)	NCBI Sequence Viewer
	EDM13139	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001099845 ⟸ NM_001106375

- UniProtKB:

B5DFH4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSEIKKQKTDQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEY
LVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDR
ENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSNYEKPETPECVLK
TNLSSVSDCVQQVVELLQEQSIVPHTTIKGIHELFVPENKIDQIRAELETLPSLPITKLDLQWV
QILSEGWATPLKGFMREKEYLQTLHFDTLLDDGVINMSIPIVLPVSGDDKARLEGCSKFALMYE
GRRVALLQDPEFYEHRKEERCSRVWGTASAKHPHIKMVMEGGDWLVGGDLQVLERIRWNDGLDQ
YRLTPLELKQKCKDMDADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTK
DDDVPLDWRMKQHAAVLEEGILDPKSTIVAIFPSPMLYAGPTEVQWHCRCRMIAGANFYIVGRD
PAGMPHPETKKDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKIKKAMDFYDPARHDEFDFIS
GTRMRKLAREGEDPPDGFMAPKAWKVLTDYYRSLEKIN

hide sequence

RefSeq Acc Id:	XP_006231336 ⟸ XM_006231274
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K950 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSEIKKQKTDQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEY LVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDR ENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSNYEKPETPECVLK TNLSSVSDCVQQVVELLQEQSIVPHTTIKGIHELFVPENKIDQIRAELETLPSLPITKLDLQWV QILSEGWATPLKGFMREKEYLQTLHFDTLLDGVILRDGVINMSIPIVLPVSGDDKARLEGCSKF ALMYEGRRVALLQDPEFYEHRKEERCSRVWGTASAKHPHIKMVMEGGDWLVGGDLQVLERIRWN DGLDQYRLTPLELKQKCKDMDADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPL GGWTKDDDVPLDWRMKQHAAVLEEGILDPKSTIVAIFPSPMLYAGPTEVQWHCRCRMIAGANFY IVGRDPAGMPHPETKKDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKIKKAMDFYDPARHDE FDFISGTRMRKLAREGEDPPDGFMAPKAWKVLTDYYRSLEKIN hide sequence

RefSeq Acc Id:

ENSRNOP00000014979 ⟸ ENSRNOT00000014979

RefSeq Acc Id:

ENSRNOP00000074860 ⟸ ENSRNOT00000083555

Protein Domains

ATP-sulfurylase PUA_2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K950-F1-model_v2	AlphaFold	A0A0G2K950	1-619	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690869

Promoter ID:

EPDNEW_R1384

Type:

multiple initiation site

Name:

Papss2_1

Description:

3'-phosphoadenosine 5'-phosphosulfate synthase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	251,145,339 - 251,145,399	EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Damaging Variants

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	251195782	251195783	A	C	snv	ACI/N (MCW)

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	236642518	236642519	A	C	snv	ACI/N (KNAW)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307012	AgrOrtholog
BioCyc Gene	G2FUF-55912	BioCyc
Ensembl Genes	ENSRNOG00000011068	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000014979	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000074860	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000014979	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000083555	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
	3.40.50.620	UniProtKB/TrEMBL
InterPro	APS_kinase_C	UniProtKB/TrEMBL
	ATP-Sase_PUA-like_dom	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	PUA-like	UniProtKB/TrEMBL
	Rossmann-like_a/b/a_fold	UniProtKB/TrEMBL
	Sulfurylase_cat_dom	UniProtKB/TrEMBL
	Sulphate_adenylyltransferase	UniProtKB/TrEMBL
KEGG Report	rno:294103	UniProtKB/TrEMBL
NCBI Gene	294103	ENTREZGENE
Pfam	ATP-sulfurylase	UniProtKB/TrEMBL
	PUA_2	UniProtKB/TrEMBL
PhenoGen	Papss2	PhenoGen
Superfamily-SCOP	PUA-like	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
TIGRFAMs	ApsK	UniProtKB/TrEMBL
	SopT	UniProtKB/TrEMBL
UniProt	A0A0G2K950	ENTREZGENE, UniProtKB/TrEMBL
	B5DFH4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	Papss2_predicted	3'-phosphoadenosine 5'-phosphosulfate synthase 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Papss2_predicted	3'-phosphoadenosine 5'-phosphosulfate synthase 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)