(2,4,5-trichlorophenoxy)acetic acid increases activity ISO RGD:10529 6480464 2 more ... CTD PMID:3032197 (9R,10S)-9,10-epoxy-9,10-dihydrophenanthrene increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein mutant form results in increased metabolism of 9 more ... CTD PMID:26838043 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 (S)-mandelic acid multiple interactions ISO RGD:736560 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of EPHX1 mRNA CTD PMID:17984292 1,1-dichloroethene increases expression ISO RGD:10529 6480464 vinylidene chloride results in increased expression of EPHX1 mRNA CTD PMID:26682919 1,2-dibromoethane decreases expression ISO RGD:10529 6480464 Ethylene Dibromide results in decreased expression of EPHX1 mRNA CTD PMID:17311802 1,2-dihydronaphthalene-1,2-diol multiple interactions ISO RGD:10529 6480464 [EPHX1 protein results in increased metabolism of naphthalene] which results in increased chemical synthesis of 1 more ... CTD PMID:18363382 , PMID:26840748 1-benzofuran increases expression ISO RGD:10529 6480464 benzofuran results in increased expression of EPHX1 mRNA CTD PMID:17311802 1-benzofuran affects expression ISO RGD:10529 6480464 benzofuran affects the expression of EPHX1 mRNA CTD PMID:17114358 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of EPHX1 mRNA CTD PMID:30723492 1-nitropropane decreases expression EXP 6480464 1-nitropropane results in decreased expression of EPHX1 mRNA CTD PMID:17070881 17alpha-ethynylestradiol affects expression ISO RGD:10529 6480464 Ethinyl Estradiol affects the expression of EPHX1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EPHX1 mRNA CTD PMID:16926038 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of EPHX1 mRNA CTD PMID:16174780 , PMID:29097150 17alpha-ethynylestradiol multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression ISO RGD:10529 6480464 Ethinyl Estradiol results in decreased expression of EPHX1 mRNA CTD PMID:16174780 17alpha-ethynylestradiol increases expression ISO RGD:10529 6480464 Ethinyl Estradiol results in increased expression of EPHX1 mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:736560 6480464 Estradiol affects the expression of EPHX1 mRNA CTD PMID:14699072 17beta-estradiol multiple interactions ISO RGD:736560 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of EPHX1 mRNA CTD PMID:30165855 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:26496021 17beta-estradiol 3-benzoate decreases expression EXP 6480464 estradiol 3-benzoate results in decreased expression of EPHX1 protein CTD PMID:24752506 1H-pyrazole increases expression ISO RGD:10529 6480464 pyrazole results in increased expression of EPHX1 mRNA CTD PMID:17945193 2,2',4,4',5,5'-hexachlorobiphenyl increases activity EXP 6480464 2 more ... CTD PMID:1372805 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,2,2-tetramine multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] CTD PMID:19634143 2,2-Bis(bromomethyl)propane-1,3-diol increases expression ISO RGD:10529 6480464 2 more ... CTD PMID:17311802 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10529 6480464 Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNA, Tetrachlorodibenzodioxin results in increased expression of EPHX1 protein CTD PMID:15328365 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10529 6480464 Tetrachlorodibenzodioxin affects the expression of EPHX1 mRNA CTD PMID:20702594 , PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNA CTD PMID:16960034 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO RGD:10529 6480464 2 more ... CTD PMID:20702594 2,3-dimethoxynaphthalene-1,4-dione decreases expression ISO RGD:736560 6480464 2 more ... CTD PMID:17547211 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 2,4-D increases activity ISO RGD:10529 6480464 2, 4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 2,4-diaminotoluene increases expression EXP 6480464 2, 4-diaminotoluene results in increased expression of EPHX1 mRNA CTD PMID:17070881 2,4-dinitrotoluene increases activity ISO RGD:10529 6480464 2, 4-dinitrotoluene results in increased activity of EPHX1 protein CTD PMID:3621371 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 2,6-diaminotoluene decreases expression EXP 6480464 2, 6-diaminotoluene results in decreased expression of EPHX1 mRNA CTD PMID:17070881 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 2-acetamidofluorene increases expression ISO RGD:10529 6480464 2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17317680 , PMID:21607683 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID increases expression ISO RGD:10529 6480464 Sulfasalazine results in increased expression of EPHX1 mRNA CTD PMID:22016648 2-nitro-p-phenylenediamine increases expression EXP 6480464 2-nitro-4-phenylenediamine results in increased expression of EPHX1 mRNA CTD PMID:17070881 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... 2-nitropropane increases expression EXP 6480464 2-nitropropane results in increased expression of EPHX1 mRNA CTD PMID:17070881 2-Oxohexane increases activity EXP 6480464 Methyl n-Butyl Ketone results in increased activity of EPHX1 protein CTD PMID:1372805 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of EPHX1 mRNA CTD PMID:20650352 2-tert-butylhydroquinone multiple interactions ISO RGD:736560 6480464 NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon] CTD PMID:24704207 2-tert-butylhydroquinone increases expression ISO RGD:736560 6480464 2-tert-butylhydroquinone results in increased expression of EPHX1 exon, 2-tert-butylhydroquinone results in increased expression of EPHX1 protein alternative form CTD PMID:24704207 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:10529 6480464 3 more ... CTD PMID:23994337 3,4-dihydrocoumarin decreases expression ISO RGD:10529 6480464 3, 4-dihydrocoumarin results in decreased expression of EPHX1 mRNA CTD PMID:22016648 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of EPHX1 mRNA CTD PMID:28522335 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 3-methylcholanthrene increases activity ISO RGD:10529 6480464 Methylcholanthrene results in increased activity of EPHX1 protein CTD PMID:3621371 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of EPHX1 mRNA CTD PMID:23273579 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of EPHX1 mRNA CTD PMID:19162173 , PMID:19695238 4,4'-sulfonyldiphenol multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA CTD PMID:28628672 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... 4-acetylaminofluorene increases expression EXP 6480464 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 4-hydroxynon-2-enal increases expression ISO RGD:10529 6480464 4-hydroxy-2-nonenal results in increased expression of EPHX1 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:10529 6480464 Fenretinide results in increased expression of EPHX1 mRNA CTD PMID:28973697 4-nitro-1,2-phenylenediamine increases expression EXP 6480464 1, 2-diamino-4-nitrobenzene results in increased expression of EPHX1 mRNA CTD PMID:17070881 4-vinylcyclohexene dioxide decreases expression EXP 6480464 4-vinyl-1-cyclohexene dioxide results in decreased expression of EPHX1 mRNA CTD PMID:8806858 4-vinylcyclohexene dioxide increases metabolic processing EXP 6480464 EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 4-vinylcyclohexene dioxide increases expression ISO RGD:10529 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA, 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein CTD PMID:22061827 4-vinylcyclohexene dioxide increases expression EXP 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA, 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein CTD PMID:22061827 , PMID:8806858 4-vinylcyclohexene dioxide increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 4-vinylcyclohexene dioxide multiple interactions EXP 6480464 [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in increased susceptibility to 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 5,6alpha-epoxy-5alpha-cholestan-3beta-ol increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of cholesterol alpha-oxide CTD PMID:2043152 5,6alpha-epoxy-5alpha-cholestan-3beta-ol multiple interactions ISO RGD:10529 6480464 disparlure promotes the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide], Lanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] CTD PMID:2043152 5-fluorouracil affects response to substance ISO RGD:736560 6480464 EPHX1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 5-fluorouracil increases expression ISO RGD:736560 6480464 Fluorouracil results in increased expression of EPHX1 mRNA CTD PMID:15205334 7,12-dimethyltetraphene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9 more ... CTD PMID:8961944 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:19027032 , PMID:24576726 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:12376462 7,12-dimethyltetraphene affects response to substance ISO RGD:10529 6480464 EPHX1 protein affects the susceptibility to 9 more ... CTD PMID:15331171 , PMID:17442664 7,12-dimethyltetraphene increases expression ISO RGD:10529 6480464 9 more ... CTD PMID:17204581 , PMID:19027032 7,12-dimethyltetraphene increases response to substance ISO RGD:10529 6480464 EPHX1 protein results in increased susceptibility to 9 more ... CTD PMID:11323178 , PMID:19027032 7,12-dimethyltetraphene multiple interactions ISO RGD:10529 6480464 [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in decreased susceptibility to 9 more ... CTD PMID:17204581 more ... 8,9-EET affects hydrolysis ISO RGD:10529 6480464 EPHX1 protein affects the hydrolysis of 8, 9-epoxyeicosatrienoic acid CTD PMID:28975360 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:736560 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EPHX1 mRNA CTD PMID:22079614 9,10-epoxy-9,10-dihydrophenanthrene increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein mutant form results in increased metabolism of 9 more ... CTD PMID:26838043 acrylamide multiple interactions ISO RGD:736560 6480464 [EPHX1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of glycidamide analog CTD PMID:21402133 acrylamide affects metabolic processing ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the metabolism of Acrylamide CTD PMID:21402133 aflatoxin B1 increases response to substance ISO RGD:736560 6480464 EPHX1 gene mutant form results in increased susceptibility to Aflatoxin B1 CTD PMID:7892276 aflatoxin B1 decreases methylation ISO RGD:736560 6480464 Aflatoxin B1 results in decreased methylation of EPHX1 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:736560 6480464 Aflatoxin B1 results in decreased expression of EPHX1 mRNA CTD PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... aflatoxin B1 affects response to substance ISO RGD:10529 6480464 EPHX1 gene SNP affects the susceptibility to Aflatoxin B1 CTD PMID:12907637 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of EPHX1 mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane increases activity EXP 6480464 alpha-hexachlorocyclohexane results in increased activity of EPHX1 protein CTD PMID:1372805 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 amitriptyline affects expression EXP 6480464 Amitriptyline affects the expression of EPHX1 mRNA CTD PMID:18355885 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EPHX1 mRNA CTD PMID:16483693 aniline increases expression ISO RGD:10529 6480464 aniline results in increased expression of EPHX1 mRNA CTD PMID:22016648 aristolochic acid increases expression EXP 6480464 aristolochic acid I results in increased expression of EPHX1 mRNA CTD PMID:17483316 aristolochic acid multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of EPHX1 mRNA CTD PMID:23912714 Aroclor 1254 increases expression ISO RGD:736560 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNA CTD PMID:17851650 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNA CTD PMID:18178546 arsenite(3-) multiple interactions ISO RGD:10529 6480464 TRP53 protein affects the reaction [arsenite results in increased expression of EPHX1 mRNA] CTD PMID:18929588 arsenite(3-) increases expression ISO RGD:10529 6480464 arsenite results in increased expression of EPHX1 mRNA CTD PMID:18929588 asbestos affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Asbestos, EPHX1 protein affects the susceptibility to Asbestos CTD PMID:15993904 , PMID:17159790 atrazine increases expression ISO RGD:736560 6480464 Atrazine results in increased expression of EPHX1 mRNA CTD PMID:22378314 azathioprine increases expression ISO RGD:736560 6480464 Azathioprine results in increased expression of EPHX1 mRNA CTD PMID:22623647 barbiturates increases activity EXP 6480464 Barbiturates results in increased activity of EPHX1 protein CTD PMID:1372805 benzene affects response to substance ISO RGD:10529 6480464 EPHX1 protein affects the susceptibility to Benzene CTD PMID:12655032 benzene affects response to substance ISO RGD:736560 6480464 EPHX1 polymorphism affects the susceptibility to Benzene CTD PMID:18784359 , PMID:18836923 benzene affects metabolic processing ISO RGD:736560 6480464 EPHX1 protein affects the metabolism of Benzene CTD PMID:10511268 benzene multiple interactions ISO RGD:736560 6480464 [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 benzene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Benzene metabolite] more ... CTD PMID:8211999 benzene increases expression ISO RGD:10529 6480464 Benzene results in increased expression of EPHX1 mRNA CTD PMID:17311802 benzene increases metabolic processing ISO RGD:736560 6480464 EPHX1 protein results in increased metabolism of Benzene CTD PMID:17885617 benzene affects expression EXP 6480464 Benzene affects the expression of EPHX1 mRNA CTD PMID:15878777 benzene multiple interactions ISO RGD:10529 6480464 EPHX1 protein affects the reaction [Benzene results in increased expression of CDKN1A mRNA] CTD PMID:12655032 benzo[a]pyrene multiple interactions ISO RGD:736560 6480464 3' more ... CTD PMID:15298956 more ... benzo[a]pyrene multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7 more ... CTD PMID:24025706 , PMID:24530354 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA CTD PMID:24025706 benzo[a]pyrene increases activity ISO RGD:736560 6480464 Benzo(a)pyrene results in increased activity of EPHX1 protein CTD PMID:16484233 benzo[a]pyrene increases expression ISO RGD:10529 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA, Benzo(a)pyrene results in increased expression of EPHX1 protein CTD PMID:19770486 more ... benzo[a]pyrene increases expression ISO RGD:736560 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA CTD PMID:15735009 more ... benzo[a]pyrene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:22759596 more ... Benzo[a]pyrene-7,8-diol multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7, 8-dihydrodiol CTD PMID:24530354 Benzo[a]pyrene-7,8-oxide multiple interactions EXP 6480464 CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7, 8-oxide] CTD PMID:12051674 benzo[b]fluoranthene increases expression ISO RGD:10529 6480464 benzo(b)fluoranthene results in increased expression of EPHX1 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA CTD PMID:27858113 benzo[c]phenanthrene multiple interactions ISO RGD:10529 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 benzo[c]phenanthrene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 benzothiazole increases expression EXP 6480464 benzothiazole results in increased expression of EPHX1 mRNA CTD PMID:8951341 beta-naphthoflavone increases expression ISO RGD:736560 6480464 beta-Naphthoflavone results in increased expression of EPHX1 mRNA CTD PMID:22258563 beta-naphthoflavone increases expression ISO RGD:10529 6480464 beta-Naphthoflavone results in increased expression of EPHX1 mRNA CTD PMID:23994337 beta-naphthoflavone decreases activity ISO RGD:10529 6480464 beta-Naphthoflavone results in decreased activity of EPHX1 protein CTD PMID:3621371 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of EPHX1 mRNA CTD PMID:23292798 bifenthrin increases expression ISO RGD:10529 6480464 bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 bis(2-ethylhexyl) phthalate increases expression ISO RGD:10529 6480464 Diethylhexyl Phthalate results in increased expression of EPHX1 mRNA, Diethylhexyl Phthalate results in increased expression of EPHX1 protein CTD PMID:19850644 , PMID:3318844 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bis(2-ethylhexyl) phthalate increases activity ISO RGD:10529 6480464 Diethylhexyl Phthalate results in increased activity of EPHX1 protein CTD PMID:3621371 bis(2-ethylhexyl) phthalate decreases activity EXP 6480464 Diethylhexyl Phthalate results in decreased activity of EPHX1 protein CTD PMID:10528994 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EPHX1 protein CTD PMID:24752506 bisphenol A increases expression ISO RGD:736560 6480464 bisphenol A results in increased expression of EPHX1 mRNA CTD PMID:29275510 bisphenol A multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EPHX1 mRNA CTD PMID:28628672 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EPHX1 mRNA, bisphenol A results in increased expression of EPHX1 protein CTD PMID:27208089 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EPHX1 mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:26496021 bisphenol A affects response to substance ISO RGD:736560 6480464 EPHX1 polymorphism affects the susceptibility to bisphenol A CTD PMID:26922413 bisphenol F multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EPHX1 mRNA CTD PMID:28628672 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of EPHX1 mRNA CTD PMID:12628495 , PMID:17538237 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of EPHX1 mRNA CTD PMID:24136188 buta-1,3-diene increases response to substance ISO RGD:736560 6480464 EPHX1 5' UTR polymorphism results in increased susceptibility to 1 more ... CTD PMID:11238181 more ... buta-1,3-diene increases response to substance ISO RGD:10529 6480464 EPHX1 gene mutant form results in increased susceptibility to 1, 3-butadiene CTD PMID:12929123 , PMID:16730686 buta-1,3-diene multiple interactions ISO RGD:736560 6480464 GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1 more ... CTD PMID:11238181 butanal decreases expression ISO RGD:736560 6480464 butyraldehyde results in decreased expression of EPHX1 mRNA CTD PMID:26079696 butylated hydroxyanisole increases activity ISO RGD:10529 6480464 Butylated Hydroxyanisole results in increased activity of EPHX1 protein CTD PMID:3621371 butyric acid multiple interactions ISO RGD:736560 6480464 Benzo(a)pyrene affects the reaction [Butyric Acid results in decreased expression of EPHX1 mRNA] CTD PMID:30439556 butyric acid decreases expression ISO RGD:736560 6480464 Butyric Acid results in decreased expression of EPHX1 mRNA CTD PMID:30439556 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of EPHX1 mRNA CTD PMID:17327699 cadmium dichloride decreases expression ISO RGD:10529 6480464 Cadmium Chloride results in decreased expression of EPHX1 mRNA CTD PMID:20061341 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of EPHX1 mRNA CTD PMID:25993096 cadmium dichloride increases expression ISO RGD:10529 6480464 Cadmium Chloride results in increased expression of EPHX1 mRNA CTD PMID:24982889 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of EPHX1 mRNA CTD PMID:17327699 carbamazepine increases expression ISO RGD:736560 6480464 Carbamazepine results in increased expression of EPHX1 mRNA CTD PMID:17112801 carbamazepine affects response to substance ISO RGD:736560 6480464 EPHX1 gene SNP affects the susceptibility to Carbamazepine, EPHX1 protein affects the susceptibility to Carbamazepine CTD PMID:19620853 , PMID:26555147 carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of EPHX1 mRNA CTD PMID:17381134 carbamazepine-10,11-epoxide multiple interactions ISO RGD:736560 6480464 [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10 more ... CTD PMID:15692831 carbon nanotube decreases expression ISO RGD:10529 6480464 Nanotubes, Carbon analog results in decreased expression of EPHX1 mRNA, Nanotubes, Carbon results in decreased expression of EPHX1 mRNA CTD PMID:25554681 , PMID:25620056 carmustine decreases expression ISO RGD:736560 6480464 Carmustine results in decreased expression of EPHX1 mRNA CTD PMID:15980968 catechol multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol] CTD PMID:8211999 chenodeoxycholic acid decreases expression ISO RGD:736560 6480464 Chenodeoxycholic Acid results in decreased expression of EPHX1 mRNA CTD PMID:27174168 chloroprene increases expression ISO RGD:10529 6480464 Chloroprene results in increased expression of EPHX1 mRNA CTD PMID:23125180 chrysene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:27858113 , PMID:8961944 chrysene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of chrysene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene] CTD PMID:8961944 ciguatoxin CTX1B affects expression ISO RGD:10529 6480464 Ciguatoxins affects the expression of EPHX1 mRNA CTD PMID:18353800 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:18246545 cisplatin multiple interactions ISO RGD:736560 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of EPHX1 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:736560 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:10529 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:21151649 , PMID:21382384 cisplatin affects expression EXP 6480464 Cisplatin affects the expression of EPHX1 mRNA CTD PMID:18246545 clofibrate decreases activity EXP 6480464 Clofibrate results in decreased activity of EPHX1 protein CTD PMID:10528994 clofibrate increases activity ISO RGD:10529 6480464 Clofibrate results in increased activity of EPHX1 protein CTD PMID:3621371 clofibrate increases expression ISO RGD:10529 6480464 Clofibrate results in increased expression of EPHX1 protein CTD PMID:3318844 , PMID:4049385 clomipramine affects expression EXP 6480464 Clomipramine affects the expression of EPHX1 mRNA CTD PMID:18355885 clonazepam increases activity EXP 6480464 Clonazepam results in increased activity of EPHX1 protein CTD PMID:1372805 clotrimazole increases activity EXP 6480464 Clotrimazole results in increased activity of EPHX1 protein CTD PMID:1372805 cobalt dichloride increases expression ISO RGD:736560 6480464 cobaltous chloride results in increased expression of EPHX1 mRNA CTD PMID:19320972 cobalt dichloride decreases expression ISO RGD:736560 6480464 cobaltous chloride results in decreased expression of EPHX1 mRNA CTD PMID:19376846 Colforsin dapropate hydrochloride affects expression ISO RGD:736560 6480464 Colforsin affects the expression of EPHX1 mRNA CTD PMID:20726872 Colforsin dapropate hydrochloride multiple interactions ISO RGD:736560 6480464 Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA] CTD PMID:20726872 copper atom multiple interactions ISO RGD:736560 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 copper(0) multiple interactions ISO RGD:736560 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 copper(2+) multiple interactions ISO RGD:736560 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 copper(II) sulfate decreases expression ISO RGD:736560 6480464 Copper Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:19549813 coumarin increases expression ISO RGD:10529 6480464 coumarin results in increased expression of EPHX1 mRNA CTD PMID:17311802 cyclophosphamide affects expression EXP 6480464 Cyclophosphamide affects the expression of EPHX1 mRNA CTD PMID:18246545 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of EPHX1 mRNA CTD PMID:18246545 cyclosporin A decreases expression ISO RGD:736560 6480464 Cyclosporine results in decreased expression of EPHX1 mRNA CTD PMID:20106945 , PMID:27989131 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of EPHX1 mRNA CTD PMID:22528246 cyproconazole increases expression ISO RGD:10529 6480464 cyproconazole results in increased expression of EPHX1 mRNA CTD PMID:22334560 cyproconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of EPHX1 mRNA CTD PMID:29038839 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of EPHX1 mRNA CTD PMID:29038839 DDT increases activity EXP 6480464 DDT results in increased activity of EPHX1 protein CTD PMID:1372805 deoxynivalenol decreases expression ISO RGD:10529 6480464 deoxynivalenol results in decreased expression of EPHX1 mRNA CTD PMID:15371230 dexamethasone multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 Diallyl sulfide increases activity EXP 6480464 allyl sulfide results in increased activity of EPHX1 protein CTD PMID:1372805 Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of EPHX1 mRNA CTD PMID:19695238 diallyl trisulfide increases expression EXP 6480464 diallyl trisulfide results in increased expression of EPHX1 mRNA CTD PMID:20650352 diazinon decreases expression ISO RGD:10529 6480464 Diazinon results in decreased expression of EPHX1 mRNA CTD PMID:17311802 dibenz[a,h]anthracene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1 more ... CTD PMID:8961944 dibenz[a,h]anthracene increases expression ISO RGD:10529 6480464 1 more ... CTD PMID:26377693 dibenz[a,h]anthracene multiple interactions ISO RGD:10529 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1 more ... CTD PMID:8961944 dibenzoylmethane increases activity ISO RGD:10529 6480464 dibenzoylmethane results in increased activity of EPHX1 protein CTD PMID:3621371 dibenzoylmethane multiple interactions ISO RGD:10529 6480464 [sulforafan co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA CTD PMID:17942926 dibenzoylmethane increases expression ISO RGD:10529 6480464 dibenzoylmethane results in increased expression of EPHX1 mRNA CTD PMID:17942926 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of EPHX1 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO RGD:10529 6480464 Dibutyl Phthalate results in decreased expression of EPHX1 mRNA CTD PMID:17361019 dichloroacetic acid increases expression ISO RGD:10529 6480464 Dichloroacetic Acid results in increased expression of EPHX1 mRNA CTD PMID:28962523 diclofenac decreases expression EXP 6480464 Diclofenac results in decreased expression of EPHX1 mRNA CTD PMID:17202759 dieldrin multiple interactions ISO RGD:10529 6480464 Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 diepoxybutane affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to diepoxybutane CTD PMID:15036125 diepoxybutane increases response to substance ISO RGD:10529 6480464 EPHX1 gene mutant form results in increased susceptibility to diepoxybutane CTD PMID:12929123 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of EPHX1 mRNA CTD PMID:15890375 Dihydroxycarbazepine multiple interactions ISO RGD:736560 6480464 [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10 more ... CTD PMID:15692831 diuron increases expression EXP 6480464 Diuron results in increased expression of EPHX1 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:736560 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 doxorubicin increases expression ISO RGD:736560 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:15205334 , PMID:29803840 doxorubicin increases expression ISO RGD:10529 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:21382384 , PMID:22016648 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:19915844 endosulfan affects expression EXP 6480464 Endosulfan affects the expression of EPHX1 mRNA CTD PMID:29391264 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of EPHX1 mRNA CTD PMID:25182419 epoxiconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of EPHX1 mRNA CTD PMID:29038839 epoxiconazole increases expression ISO RGD:10529 6480464 epoxiconazole results in increased expression of EPHX1 mRNA CTD PMID:22334560 ethanol increases expression EXP 6480464 Ethanol results in increased expression of EPHX1 mRNA CTD PMID:23273579 ethanol multiple interactions ISO RGD:10529 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of EPHX1 mRNA CTD PMID:30517762 ethoxyquin increases expression EXP 6480464 Ethoxyquin results in increased expression of EPHX1 mRNA CTD PMID:19695238 etoposide increases expression ISO RGD:10529 6480464 Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384 , PMID:25270620 felbamate increases expression EXP 6480464 felbamate results in increased expression of EPHX1 mRNA CTD PMID:17381134 fenamidone increases expression ISO RGD:10529 6480464 fenamidone results in increased expression of EPHX1 mRNA CTD PMID:27029645 fenvalerate increases activity EXP 6480464 fenvalerate metabolite results in increased activity of EPHX1 protein CTD PMID:10630566 finasteride increases expression EXP 6480464 Finasteride results in increased expression of EPHX1 mRNA CTD PMID:24136188 fipronil increases expression EXP 6480464 fipronil results in increased expression of EPHX1 mRNA CTD PMID:23962444 flutamide increases expression EXP 6480464 Flutamide results in increased expression of EPHX1 mRNA CTD PMID:24136188 fumonisin B1 increases expression ISO RGD:10529 6480464 fumonisin B1 results in increased expression of EPHX1 mRNA CTD PMID:16221962 furan increases methylation EXP 6480464 furan results in increased methylation of EPHX1 gene CTD PMID:22079235 furan increases expression EXP 6480464 furan results in increased expression of EPHX1 mRNA CTD PMID:25539665 , PMID:26194646 furan increases expression ISO RGD:10529 6480464 furan results in increased expression of EPHX1 mRNA CTD PMID:24183702 genistein increases expression ISO RGD:736560 6480464 Genistein results in increased expression of EPHX1 mRNA CTD PMID:18847459 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of EPHX1 mRNA CTD PMID:24136188 glucoerucin increases expression EXP 6480464 glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 glucoerucin(1-) increases expression EXP 6480464 glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 glucoraphanin increases expression EXP 6480464 glucoraphanin results in increased expression of EPHX1 protein CTD PMID:21132492 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of EPHX1 mRNA CTD PMID:15345336 Heptachlor epoxide multiple interactions ISO RGD:10529 6480464 Heptachlor Epoxide promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of EPHX1 mRNA CTD PMID:21905055 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of EPHX1 mRNA CTD PMID:15159207 HT-2 Toxin increases expression ISO RGD:736560 6480464 HT-2 toxin results in increased expression of EPHX1 mRNA CTD PMID:22982764 hydrogen peroxide increases expression ISO RGD:10529 6480464 Hydrogen Peroxide results in increased expression of EPHX1 mRNA CTD PMID:21382384 hydroquinone multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone], EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 imipramine affects expression EXP 6480464 Imipramine affects the expression of EPHX1 mRNA CTD PMID:18355885 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of EPHX1 mRNA CTD PMID:21396975 indometacin multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of EPHX1 mRNA CTD PMID:18355885 kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA, [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNA CTD PMID:18544905 L-ascorbic acid multiple interactions ISO RGD:736560 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 lanosterol multiple interactions ISO RGD:10529 6480464 Lanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] CTD PMID:2043152 lead(0) affects expression ISO RGD:736560 6480464 Lead affects the expression of EPHX1 mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:736560 6480464 Lead affects the expression of EPHX1 mRNA CTD PMID:28903495 levofloxacin decreases expression EXP 6480464 Levofloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 lithocholic acid multiple interactions ISO RGD:10529 6480464 [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA CTD PMID:20359477 malathion decreases expression ISO RGD:10529 6480464 Malathion results in decreased expression of EPHX1 mRNA CTD PMID:17311802 mandelic acid multiple interactions ISO RGD:736560 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 medroxyprogesterone acetate multiple interactions ISO RGD:736560 6480464 ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein] CTD PMID:20383792 medroxyprogesterone acetate increases expression ISO RGD:736560 6480464 Medroxyprogesterone Acetate results in increased expression of EPHX1 mRNA, Medroxyprogesterone Acetate results in increased expression of EPHX1 protein CTD PMID:20383792 menadione increases expression ISO RGD:10529 6480464 Vitamin K 3 results in increased expression of EPHX1 mRNA CTD PMID:21382384 methamphetamine increases expression ISO RGD:10529 6480464 Methamphetamine results in increased expression of EPHX1 mRNA CTD PMID:26307267 methamphetamine increases methylation ISO RGD:10529 6480464 Methamphetamine results in increased methylation of EPHX1 promoter CTD PMID:26307267 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of EPHX1 mRNA CTD PMID:15890375 methyl methanesulfonate increases expression ISO RGD:10529 6480464 Methyl Methanesulfonate results in increased expression of EPHX1 mRNA CTD PMID:21382384 mitomycin C increases expression ISO RGD:10529 6480464 Mitomycin results in increased expression of EPHX1 mRNA CTD PMID:21382384 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of EPHX1 mRNA CTD PMID:12706301 muconic acid multiple interactions ISO RGD:736560 6480464 [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 N,N'-diphenylthiourea increases expression EXP 6480464 diphenylthiourea results in increased expression of EPHX1 mRNA, diphenylthiourea results in increased expression of EPHX1 protein CTD PMID:10190572 N,N-diethyl-m-toluamide increases expression ISO RGD:736560 6480464 DEET results in increased expression of EPHX1 mRNA CTD PMID:27091632 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:10529 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX1 mRNA CTD PMID:20061341 N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:15954086 N-methyl-N-nitrosourea increases expression ISO RGD:10529 6480464 Methylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:21382384 N-Methylolacrylamide decreases expression ISO RGD:10529 6480464 N-methylolacrylamide results in decreased expression of EPHX1 mRNA CTD PMID:17311802 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA more ... CTD PMID:18544905 more ... N-nitrosodiethylamine increases expression ISO RGD:10529 6480464 Diethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:17854601 , PMID:21607683 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:17602206 more ... N-nitrosodiethylamine multiple interactions ISO RGD:10529 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPHX1 mRNA] CTD PMID:17854601 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:14600272 , PMID:15890375 naphthalene increases expression ISO RGD:736560 6480464 naphthalene results in increased expression of EPHX1 mRNA CTD PMID:20500019 naphthalene increases response to substance ISO RGD:10529 6480464 EPHX1 results in increased susceptibility to naphthalene CTD PMID:26840748 naphthalene increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of naphthalene CTD PMID:18363382 , PMID:26840748 naphthalene multiple interactions ISO RGD:10529 6480464 [EPHX1 protein results in increased metabolism of naphthalene] which results in increased chemical synthesis of 1 more ... CTD PMID:18363382 , PMID:26840748 naphthalene-1,5-diamine affects expression ISO RGD:10529 6480464 1, 5-naphthalenediamine affects the expression of EPHX1 mRNA CTD PMID:17114358 naphthalene-1,5-diamine increases expression ISO RGD:10529 6480464 1, 5-naphthalenediamine results in increased expression of EPHX1 mRNA CTD PMID:17311802 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of EPHX1 mRNA CTD PMID:24136188 nickel atom decreases expression ISO RGD:736560 6480464 Nickel results in decreased expression of EPHX1 mRNA CTD PMID:25583101 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of EPHX1 mRNA CTD PMID:24136188 nimesulide decreases glutathionylation ISO RGD:736560 6480464 EPHX1 protein results in decreased glutathionylation of nimesulide CTD PMID:26524229 organoselenium compound increases activity ISO RGD:10529 6480464 Organoselenium Compounds results in increased activity of EPHX1 protein CTD PMID:17163488 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of EPHX1 mRNA CTD PMID:25729387 oxirane affects metabolic processing ISO RGD:736560 6480464 EPHX1 protein affects the metabolism of Ethylene Oxide CTD PMID:11437638 oxirane affects metabolic processing EXP 6480464 EPHX1 protein affects the metabolism of Ethylene Oxide CTD PMID:11437638 ozone decreases expression ISO RGD:10529 6480464 Ozone results in decreased expression of EPHX1 mRNA CTD PMID:12763052 p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of EPHX1 mRNA CTD PMID:27638505 paracetamol affects expression ISO RGD:10529 6480464 Acetaminophen affects the expression of EPHX1 mRNA CTD PMID:15606129 , PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EPHX1 mRNA CTD PMID:30723492 paracetamol increases expression ISO RGD:736560 6480464 Acetaminophen results in increased expression of EPHX1 mRNA CTD PMID:22230336 paracetamol multiple interactions ISO RGD:10529 6480464 [Acetaminophen results in increased activity of and results in increased localization of NFE2L2 protein] which results in increased expression of EPHX1 mRNA CTD PMID:15122755 pentachloronitrobenzene increases expression ISO RGD:10529 6480464 quintozene results in increased expression of EPHX1 mRNA CTD PMID:17311802 pentachlorophenol increases expression ISO RGD:10529 6480464 Pentachlorophenol results in increased expression of EPHX1 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid increases expression ISO RGD:736560 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:27153767 perfluorooctane-1-sulfonic acid increases expression ISO RGD:10529 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:20936131 perfluorooctane-1-sulfonic acid affects expression ISO RGD:10529 6480464 perfluorooctane sulfonic acid affects the expression of EPHX1 mRNA CTD PMID:19429403 perfluorooctanoic acid affects expression ISO RGD:10529 6480464 perfluorooctanoic acid affects the expression of EPHX1 mRNA CTD PMID:18281256 , PMID:19429403 perfluorooctanoic acid decreases expression ISO RGD:10529 6480464 perfluorooctanoic acid results in decreased expression of EPHX1 protein CTD PMID:28126411 perfluorooctanoic acid multiple interactions ISO RGD:10529 6480464 [perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of EPHX1 mRNA CTD PMID:23626681 perfluorooctanoic acid increases expression ISO RGD:10529 6480464 perfluorooctanoic acid results in increased expression of EPHX1 mRNA CTD PMID:23626681 permethrin increases expression ISO RGD:10529 6480464 Permethrin results in increased expression of EPHX1 mRNA CTD PMID:30629241 phenethyl isothiocyanate increases expression EXP 6480464 phenethyl isothiocyanate results in increased expression of EPHX1 protein CTD PMID:21132492 phenobarbital multiple interactions ISO RGD:10529 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of EPHX1 mRNA], NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of EPHX1 mRNA] CTD PMID:19482888 , PMID:19850644 phenobarbital increases expression ISO RGD:736560 6480464 Phenobarbital results in increased expression of EPHX1 mRNA, Phenobarbital results in increased expression of EPHX1 protein CTD PMID:22258563 , PMID:28541575 phenobarbital affects expression ISO RGD:10529 6480464 Phenobarbital affects the expression of EPHX1 mRNA CTD PMID:23091169 phenobarbital increases expression ISO RGD:10529 6480464 Phenobarbital results in increased expression of EPHX1 mRNA CTD PMID:19482888 more ... phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of EPHX1 mRNA, Phenobarbital results in increased expression of EPHX1 protein CTD PMID:11328961 more ... phenobarbital affects expression ISO RGD:736560 6480464 Phenobarbital affects the expression of EPHX1 mRNA CTD PMID:19159669 phenobarbital increases activity ISO RGD:10529 6480464 Phenobarbital results in increased activity of EPHX1 protein CTD PMID:3621371 phenobarbital multiple interactions EXP 6480464 [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of EPHX1 protein CTD PMID:20935162 phenol multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol] more ... CTD PMID:8211999 phenols increases expression ISO RGD:736560 6480464 Phenols results in increased expression of EPHX1 mRNA CTD PMID:23561572 phenylglyoxylic acid multiple interactions ISO RGD:736560 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 phenylmercury acetate increases expression ISO RGD:736560 6480464 Phenylmercuric Acetate results in increased expression of EPHX1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736560 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 phenytoin affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Phenytoin CTD PMID:19952982 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of EPHX1 mRNA CTD PMID:17381134 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased expression of EPHX1 mRNA CTD PMID:12376462 phlorizin decreases expression ISO RGD:10529 6480464 Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate decreases expression ISO RGD:736560 6480464 Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein CTD PMID:24704207 phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of EPHX1 mRNA, phosphoramide mustard results in increased expression of EPHX1 protein CTD PMID:25070981 pimecrolimus multiple interactions ISO RGD:736560 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA] CTD PMID:29356861 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of EPHX1 mRNA CTD PMID:15890375 , PMID:22484513 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of EPHX1 mRNA CTD PMID:19162173 pirinixic acid increases expression ISO RGD:10529 6480464 pirinixic acid results in increased expression of EPHX1 mRNA CTD PMID:15375163 more ... pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of EPHX1 mRNA CTD PMID:15890375 pirinixic acid multiple interactions ISO RGD:10529 6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of EPHX1 mRNA] CTD PMID:16221962 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:10529 6480464 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA CTD PMID:20359477 , PMID:27413110 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:10529 6480464 [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA CTD PMID:20359477 propiconazole affects expression EXP 6480464 propiconazole affects the expression of EPHX1 mRNA CTD PMID:17383973 propiconazole increases expression ISO RGD:10529 6480464 propiconazole results in increased expression of EPHX1 mRNA CTD PMID:21278054 , PMID:22334560 propionamide decreases activity EXP 6480464 propionamide analog results in decreased activity of EPHX1 protein CTD PMID:18363382 propionamide decreases activity ISO RGD:10529 6480464 propionamide analog results in decreased activity of EPHX1 protein CTD PMID:18363382 propionamide multiple interactions ISO RGD:10529 6480464 [propionamide analog results in decreased activity of EPHX1 protein] which results in increased glutathionylation of naphthalene CTD PMID:18363382 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of EPHX1 mRNA CTD PMID:22431067 quartz decreases expression ISO RGD:736560 6480464 Quartz results in decreased expression of EPHX1 mRNA CTD PMID:27917503 quercetin multiple interactions ISO RGD:736560 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 quercetin increases expression EXP 6480464 Quercetin results in increased expression of EPHX1 mRNA CTD PMID:18095365 , PMID:21565894 resveratrol multiple interactions ISO RGD:736560 6480464 resveratrol promotes the reaction [Benzo(a)pyrene results in increased activity of EPHX1 protein] CTD PMID:16484233 resveratrol affects expression ISO RGD:10529 6480464 resveratrol affects the expression of EPHX1 mRNA CTD PMID:23525482 resveratrol increases expression ISO RGD:736560 6480464 resveratrol results in increased expression of EPHX1 mRNA, resveratrol results in increased expression of EPHX1 protein CTD PMID:11279601 , PMID:18089832 rifampicin increases expression ISO RGD:736560 6480464 Rifampin results in increased expression of EPHX1 mRNA CTD PMID:22258563 more ... rifampicin multiple interactions ISO RGD:736560 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA] CTD PMID:29356861 rotenone increases expression ISO RGD:10529 6480464 Rotenone results in increased expression of EPHX1 mRNA CTD PMID:22016648 SB 431542 multiple interactions ISO RGD:736560 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of EPHX1 mRNA CTD PMID:15967596 silicon dioxide decreases expression ISO RGD:736560 6480464 Silicon Dioxide analog results in decreased expression of EPHX1 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO RGD:736560 6480464 Silicon Dioxide results in increased expression of EPHX1 mRNA CTD PMID:27917503 silver atom multiple interactions ISO RGD:736560 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 silver atom increases expression ISO RGD:10529 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 silver atom increases expression ISO RGD:736560 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 silver(0) multiple interactions ISO RGD:736560 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 silver(0) increases expression ISO RGD:10529 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:736560 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 silver(1+) increases expression ISO RGD:10529 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 silver(1+) multiple interactions ISO RGD:736560 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 silver(1+) increases expression ISO RGD:736560 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 sodium arsenite increases expression ISO RGD:736560 6480464 sodium arsenite results in increased expression of EPHX1 mRNA CTD PMID:25493608 sodium dichromate decreases expression ISO RGD:10529 6480464 sodium bichromate results in decreased expression of EPHX1 mRNA CTD PMID:22155349 stilbene oxide multiple interactions ISO RGD:10529 6480464 araldite promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide analog] more ... CTD PMID:2043152 stilbene oxide increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of stilbene oxide, EPHX1 protein results in increased metabolism of stilbene oxide analog CTD PMID:2043152 stilbenoid increases activity ISO RGD:10529 6480464 Stilbenes results in increased activity of EPHX1 protein CTD PMID:3621371 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of EPHX1 protein CTD PMID:19634143 streptozocin multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] CTD PMID:19634143 styrene increases expression EXP 6480464 Styrene results in increased expression of EPHX1 mRNA CTD PMID:16418063 styrene decreases response to substance ISO RGD:10529 6480464 EPHX1 protein results in decreased susceptibility to Styrene CTD PMID:22386858 styrene affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Styrene CTD PMID:14751678 styrene oxide multiple interactions EXP 6480464 CYP1A1 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] more ... CTD PMID:12051674 styrene oxide multiple interactions ISO RGD:736560 6480464 EPHX1 protein affects the metabolism of and results in decreased activity of styrene oxide CTD PMID:12694745 styrene oxide affects hydrolysis ISO RGD:736560 6480464 EPHX1 protein affects the hydrolysis of styrene oxide CTD PMID:11076696 sulfasalazine increases expression ISO RGD:10529 6480464 Sulfasalazine results in increased expression of EPHX1 mRNA CTD PMID:22016648 sulforaphane increases expression ISO RGD:10529 6480464 sulforafan results in increased expression of EPHX1 mRNA CTD PMID:17942926 sulforaphane increases expression ISO RGD:736560 6480464 sulforafan results in increased expression of EPHX1 exon more ... CTD PMID:24704207 sulforaphane multiple interactions ISO RGD:736560 6480464 sulforafan promotes the reaction [NFE2L2 protein binds to EPHX1 enhancer] CTD PMID:24704207 sulforaphane multiple interactions ISO RGD:10529 6480464 [sulforafan co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA CTD PMID:17942926 tamoxifen affects expression ISO RGD:736560 6480464 Tamoxifen affects the expression of EPHX1 mRNA CTD PMID:14699072 tamoxifen affects expression ISO RGD:10529 6480464 Tamoxifen affects the expression of EPHX1 mRNA CTD PMID:17555576 tert-butyl ethyl ether increases expression EXP 6480464 ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 tert-butyl hydroperoxide increases expression ISO RGD:10529 6480464 tert-Butylhydroperoxide results in increased expression of EPHX1 mRNA CTD PMID:21382384 tetrachloromethane decreases expression ISO RGD:10529 6480464 Carbon Tetrachloride results in decreased expression of EPHX1 mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO RGD:10529 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of EPHX1 mRNA CTD PMID:30517762 tetrachloromethane multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA], thymoquinone inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA] CTD PMID:21994235 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of EPHX1 mRNA CTD PMID:21994235 tetracycline decreases expression ISO RGD:10529 6480464 Tetracycline results in decreased expression of EPHX1 mRNA CTD PMID:24489787 tetraphene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:27858113 , PMID:8961944 tetraphene increases expression ISO RGD:10529 6480464 benz(a)anthracene results in increased expression of EPHX1 protein CTD PMID:2208584 tetraphene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benz(a)anthracene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene] CTD PMID:8961944 thiazoles increases expression EXP 6480464 Thiazoles results in increased expression of EPHX1 mRNA CTD PMID:8951341 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of EPHX1 mRNA CTD PMID:28943392 titanium dioxide decreases expression ISO RGD:10529 6480464 titanium dioxide results in decreased expression of EPHX1 mRNA CTD PMID:23557971 , PMID:27760801 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 Tridiphane multiple interactions ISO RGD:10529 6480464 tridiphane promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 tris(2-butoxyethyl) phosphate affects expression ISO RGD:736560 6480464 tris(2-butoxyethyl) phosphate affects the expression of EPHX1 mRNA CTD PMID:29024780 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of EPHX1 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:736560 6480464 Valproic Acid results in decreased methylation of EPHX1 gene CTD PMID:29154799 , PMID:29501571 valproic acid decreases expression ISO RGD:736560 6480464 Valproic Acid results in decreased expression of EPHX1 mRNA CTD PMID:29501571 valproic acid multiple interactions ISO RGD:736560 6480464 Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA] CTD PMID:20726872 valproic acid increases expression ISO RGD:10529 6480464 Valproic Acid results in increased expression of EPHX1 mRNA CTD PMID:21427059 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of EPHX1 mRNA CTD PMID:17381134 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of EPHX1 mRNA CTD PMID:19015723 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of EPHX1 mRNA CTD PMID:23034163 vincristine decreases expression ISO RGD:10529 6480464 Vincristine results in decreased expression of EPHX1 mRNA CTD PMID:21382384 warfarin affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Warfarin more ... CTD PMID:15900282 more ... warfarin increases response to substance ISO RGD:736560 6480464 EPHX1 protein results in increased susceptibility to Warfarin CTD PMID:17496169 zinc atom increases expression EXP 6480464 Zinc results in increased expression of EPHX1 mRNA CTD PMID:17074742 zinc sulfate increases expression EXP 6480464 Zinc Sulfate results in increased expression of EPHX1 mRNA CTD PMID:17074742 zinc(0) increases expression EXP 6480464 Zinc results in increased expression of EPHX1 mRNA CTD PMID:17074742
Gene-Chemical Interaction Annotations
