(1->4)-beta-D-glucan multiple interactions ISO RGD:10529 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of EPHX1 mRNA CTD PMID:36331819 (2,4,5-trichlorophenoxy)acetic acid increases activity ISO RGD:10529 6480464 2 more ... CTD PMID:3032197 (9R,10S)-9,10-epoxy-9,10-dihydrophenanthrene increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein mutant form results in increased metabolism of 9 more ... CTD PMID:26838043 (S)-mandelic acid multiple interactions ISO RGD:736560 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of EPHX1 mRNA CTD PMID:17984292 1,1-dichloroethene increases expression ISO RGD:10529 6480464 vinylidene chloride results in increased expression of EPHX1 mRNA CTD PMID:26682919 1,2-dibromoethane decreases expression ISO RGD:10529 6480464 Ethylene Dibromide results in decreased expression of EPHX1 mRNA CTD PMID:17311802 1,2-dihydronaphthalene-1,2-diol multiple interactions ISO RGD:10529 6480464 [EPHX1 protein results in increased metabolism of naphthalene] which results in increased chemical synthesis of 1 more ... CTD PMID:18363382 , PMID:26840748 1,2-dimethylhydrazine increases expression ISO RGD:10529 6480464 1, 2-Dimethylhydrazine results in increased expression of EPHX1 mRNA CTD PMID:22206623 1,3,5-trimethylbenzene increases expression ISO RGD:736560 6480464 mesitylene results in increased expression of EPHX1 mRNA CTD PMID:33269480 1,4-dioxane increases expression ISO RGD:10529 6480464 1, 4-dioxane results in increased expression of EPHX1 mRNA CTD PMID:33693819 1-benzofuran increases expression ISO RGD:10529 6480464 benzofuran results in increased expression of EPHX1 mRNA CTD PMID:17311802 1-benzofuran affects expression ISO RGD:10529 6480464 benzofuran affects the expression of EPHX1 mRNA CTD PMID:17114358 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of EPHX1 mRNA CTD PMID:30723492 1-nitropropane decreases expression EXP 6480464 1-nitropropane results in decreased expression of EPHX1 mRNA CTD PMID:17070881 17alpha-ethynylestradiol affects expression ISO RGD:10529 6480464 Ethinyl Estradiol affects the expression of EPHX1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EPHX1 mRNA CTD PMID:16926038 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of EPHX1 mRNA CTD PMID:16174780 , PMID:29097150 17alpha-ethynylestradiol multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression ISO RGD:10529 6480464 Ethinyl Estradiol results in decreased expression of EPHX1 mRNA CTD PMID:16174780 17alpha-ethynylestradiol increases expression ISO RGD:10529 6480464 Ethinyl Estradiol results in increased expression of EPHX1 mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:736560 6480464 Estradiol affects the expression of EPHX1 mRNA CTD PMID:14699072 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of EPHX1 protein CTD PMID:32145629 17beta-estradiol multiple interactions ISO RGD:736560 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of EPHX1 mRNA CTD PMID:30165855 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:26496021 17beta-estradiol 3-benzoate decreases expression EXP 6480464 estradiol 3-benzoate results in decreased expression of EPHX1 protein CTD PMID:24752506 1H-pyrazole increases expression ISO RGD:10529 6480464 pyrazole results in increased expression of EPHX1 mRNA CTD PMID:17945193 2,2',4,4',5,5'-hexachlorobiphenyl increases activity EXP 6480464 2 more ... CTD PMID:1372805 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:31826744 , PMID:32679240 2,2,2-tetramine multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] CTD PMID:19634143 2,2-Bis(bromomethyl)propane-1,3-diol increases expression ISO RGD:10529 6480464 2 more ... CTD PMID:17311802 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10529 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPHX1 mRNA CTD PMID:33956508 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10529 6480464 Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNA, Tetrachlorodibenzodioxin results in increased expression of EPHX1 protein CTD PMID:15328365 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10529 6480464 Tetrachlorodibenzodioxin affects the expression of EPHX1 mRNA CTD PMID:20702594 , PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNA CTD PMID:16960034 more ... 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO RGD:10529 6480464 2 more ... CTD PMID:20702594 2,3-dimethoxynaphthalene-1,4-dione decreases expression ISO RGD:736560 6480464 2 more ... CTD PMID:17547211 2,4,6-tribromophenol increases expression ISO RGD:736560 6480464 2 more ... CTD PMID:31675489 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 2,4-D increases activity ISO RGD:10529 6480464 2, 4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 2,4-diaminotoluene increases expression EXP 6480464 2, 4-diaminotoluene results in increased expression of EPHX1 mRNA CTD PMID:17070881 2,4-dinitrotoluene increases activity ISO RGD:10529 6480464 2, 4-dinitrotoluene results in increased activity of EPHX1 protein CTD PMID:3621371 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 2,6-diaminotoluene decreases expression EXP 6480464 2, 6-diaminotoluene results in decreased expression of EPHX1 mRNA CTD PMID:17070881 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 2,8-bis-Trifluoromethyl-4-quinoline carboxylic acid increases expression ISO RGD:736560 6480464 Ro 21-5104 results in increased expression of EPHX1 mRNA CTD PMID:25313206 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 2-acetamidofluorene increases expression ISO RGD:10529 6480464 2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17317680 , PMID:21607683 2-nitro-p-phenylenediamine increases expression EXP 6480464 2-nitro-4-phenylenediamine results in increased expression of EPHX1 mRNA CTD PMID:17070881 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... 2-nitropropane increases expression EXP 6480464 2-nitropropane results in increased expression of EPHX1 mRNA CTD PMID:17070881 2-Oxohexane increases activity EXP 6480464 Methyl n-Butyl Ketone results in increased activity of EPHX1 protein CTD PMID:1372805 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of EPHX1 mRNA CTD PMID:20650352 2-tert-butylhydroquinone multiple interactions ISO RGD:736560 6480464 NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon] CTD PMID:24704207 2-tert-butylhydroquinone increases expression ISO RGD:736560 6480464 2-tert-butylhydroquinone results in increased expression of EPHX1 exon, 2-tert-butylhydroquinone results in increased expression of EPHX1 protein alternative form CTD PMID:24704207 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:10529 6480464 3 more ... CTD PMID:23994337 3,4-dihydrocoumarin decreases expression ISO RGD:10529 6480464 3, 4-dihydrocoumarin results in decreased expression of EPHX1 mRNA CTD PMID:22016648 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of EPHX1 mRNA, alpha-Chlorohydrin results in increased expression of EPHX1 protein CTD PMID:28522335 , PMID:34915118 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 3-methylcholanthrene increases activity ISO RGD:10529 6480464 Methylcholanthrene results in increased activity of EPHX1 protein CTD PMID:3621371 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of EPHX1 mRNA CTD PMID:23273579 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of EPHX1 mRNA CTD PMID:19162173 , PMID:19695238 4,4'-sulfonyldiphenol multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA CTD PMID:36041667 4,4'-sulfonyldiphenol decreases expression ISO RGD:10529 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of EPHX1 mRNA CTD PMID:30951980 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... 4-acetylaminofluorene increases expression EXP 6480464 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 4-hydroxynon-2-enal increases expression ISO RGD:10529 6480464 4-hydroxy-2-nonenal results in increased expression of EPHX1 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:10529 6480464 Fenretinide results in increased expression of EPHX1 mRNA CTD PMID:28973697 4-nitro-1,2-phenylenediamine increases expression EXP 6480464 1, 2-diamino-4-nitrobenzene results in increased expression of EPHX1 mRNA CTD PMID:17070881 4-vinylcyclohexene dioxide decreases expression EXP 6480464 4-vinyl-1-cyclohexene dioxide results in decreased expression of EPHX1 mRNA CTD PMID:8806858 4-vinylcyclohexene dioxide increases metabolic processing EXP 6480464 EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 4-vinylcyclohexene dioxide increases expression ISO RGD:10529 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA, 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein CTD PMID:22061827 4-vinylcyclohexene dioxide increases expression EXP 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA, 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein CTD PMID:22061827 , PMID:8806858 4-vinylcyclohexene dioxide increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 4-vinylcyclohexene dioxide multiple interactions EXP 6480464 [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in increased susceptibility to 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 5,6alpha-epoxy-5alpha-cholestan-3beta-ol increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of cholesterol alpha-oxide CTD PMID:2043152 5,6alpha-epoxy-5alpha-cholestan-3beta-ol multiple interactions ISO RGD:10529 6480464 disparlure promotes the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide], Lanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] CTD PMID:2043152 5-aza-2'-deoxycytidine increases expression ISO RGD:736560 6480464 Decitabine results in increased expression of EPHX1 mRNA CTD PMID:19194470 5-fluorouracil affects response to substance ISO RGD:736560 6480464 EPHX1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 5-fluorouracil increases expression ISO RGD:736560 6480464 Fluorouracil results in increased expression of EPHX1 mRNA CTD PMID:15205334 7,12-dimethyltetraphene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9 more ... CTD PMID:8961944 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:19027032 , PMID:24576726 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:12376462 7,12-dimethyltetraphene affects response to substance ISO RGD:10529 6480464 EPHX1 protein affects the susceptibility to 9 more ... CTD PMID:15331171 , PMID:17442664 7,12-dimethyltetraphene increases expression ISO RGD:10529 6480464 9 more ... CTD PMID:17204581 , PMID:19027032 7,12-dimethyltetraphene increases response to substance ISO RGD:10529 6480464 EPHX1 protein results in increased susceptibility to 9 more ... CTD PMID:11323178 , PMID:19027032 7,12-dimethyltetraphene multiple interactions ISO RGD:10529 6480464 [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in decreased susceptibility to 9 more ... CTD PMID:17204581 more ... 8,9-EET affects hydrolysis ISO RGD:10529 6480464 EPHX1 protein affects the hydrolysis of 8, 9-epoxyeicosatrienoic acid CTD PMID:28975360 8-Br-cAMP increases expression ISO RGD:736560 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EPHX1 mRNA CTD PMID:22079614 9,10-epoxy-9,10-dihydrophenanthrene increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein mutant form results in increased metabolism of 9 more ... CTD PMID:26838043 acetamide increases expression EXP 6480464 acetamide results in increased expression of EPHX1 mRNA CTD PMID:31881176 acrylamide multiple interactions ISO RGD:736560 6480464 [EPHX1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of glycidamide analog CTD PMID:21402133 acrylamide increases expression ISO RGD:736560 6480464 Acrylamide results in increased expression of EPHX1 mRNA CTD PMID:32763439 acrylamide affects metabolic processing ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the metabolism of Acrylamide CTD PMID:21402133 aflatoxin B1 increases response to substance ISO RGD:736560 6480464 EPHX1 gene mutant form results in increased susceptibility to Aflatoxin B1 CTD PMID:7892276 aflatoxin B1 increases activity EXP 152998935 aflatoxin increases Ephx1 enzyme activity in rat liver microsomes RGD aflatoxin B1 decreases methylation ISO RGD:736560 6480464 Aflatoxin B1 results in decreased methylation of EPHX1 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:736560 6480464 Aflatoxin B1 results in decreased expression of EPHX1 mRNA CTD PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... aflatoxin B1 affects response to substance ISO RGD:10529 6480464 EPHX1 gene SNP affects the susceptibility to Aflatoxin B1 CTD PMID:12907637 all-trans-retinoic acid multiple interactions ISO RGD:10529 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EPHX1 mRNA CTD PMID:30951980 all-trans-retinoic acid decreases expression ISO RGD:736560 6480464 Tretinoin results in decreased expression of EPHX1 mRNA CTD PMID:33167477 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of EPHX1 mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane increases activity EXP 6480464 alpha-hexachlorocyclohexane results in increased activity of EPHX1 protein CTD PMID:1372805 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 amitriptyline affects expression EXP 6480464 Amitriptyline affects the expression of EPHX1 mRNA CTD PMID:18355885 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EPHX1 mRNA CTD PMID:16483693 aniline increases expression ISO RGD:10529 6480464 aniline results in increased expression of EPHX1 mRNA CTD PMID:22016648 antimonite multiple interactions ISO RGD:736560 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of EPHX1 mRNA CTD PMID:17483316 aristolochic acid A increases expression ISO RGD:736560 6480464 aristolochic acid I results in increased expression of EPHX1 mRNA CTD PMID:33212167 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of EPHX1 mRNA CTD PMID:23912714 Aroclor 1254 increases expression ISO RGD:736560 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNA CTD PMID:17851650 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNA CTD PMID:18178546 arsenite(3-) multiple interactions ISO RGD:10529 6480464 TRP53 protein affects the reaction [arsenite results in increased expression of EPHX1 mRNA] CTD PMID:18929588 arsenite(3-) multiple interactions ISO RGD:736560 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 arsenite(3-) increases expression ISO RGD:10529 6480464 arsenite results in increased expression of EPHX1 mRNA CTD PMID:18929588 arsenous acid decreases expression ISO RGD:736560 6480464 Arsenic Trioxide results in decreased expression of EPHX1 mRNA CTD PMID:17547211 asbestos affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Asbestos, EPHX1 protein affects the susceptibility to Asbestos CTD PMID:15993904 , PMID:17159790 atazanavir sulfate multiple interactions ISO RGD:736560 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:32152650 atazanavir sulfate decreases expression ISO RGD:736560 6480464 Atazanavir Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:32152650 atrazine increases expression ISO RGD:736560 6480464 Atrazine results in increased expression of EPHX1 mRNA CTD PMID:22378314 azathioprine increases expression ISO RGD:736560 6480464 Azathioprine results in increased expression of EPHX1 mRNA CTD PMID:22623647 barbiturates increases activity EXP 6480464 Barbiturates results in increased activity of EPHX1 protein CTD PMID:1372805 benzene affects response to substance ISO RGD:10529 6480464 EPHX1 protein affects the susceptibility to Benzene CTD PMID:12655032 benzene increases expression ISO RGD:736560 6480464 Benzene results in increased expression of EPHX1 mRNA CTD PMID:33269480 benzene affects response to substance ISO RGD:736560 6480464 EPHX1 polymorphism affects the susceptibility to Benzene CTD PMID:18784359 , PMID:18836923 benzene affects metabolic processing ISO RGD:736560 6480464 EPHX1 protein affects the metabolism of Benzene CTD PMID:10511268 benzene multiple interactions ISO RGD:736560 6480464 [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 benzene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Benzene metabolite] more ... CTD PMID:8211999 benzene increases expression ISO RGD:10529 6480464 Benzene results in increased expression of EPHX1 mRNA CTD PMID:17311802 benzene increases metabolic processing ISO RGD:736560 6480464 EPHX1 protein results in increased metabolism of Benzene CTD PMID:17885617 benzene affects expression EXP 6480464 Benzene affects the expression of EPHX1 mRNA CTD PMID:15878777 benzene multiple interactions ISO RGD:10529 6480464 EPHX1 protein affects the reaction [Benzene results in increased expression of CDKN1A mRNA] CTD PMID:12655032 benzo[a]pyrene multiple interactions ISO RGD:736560 6480464 3' more ... CTD PMID:15298956 more ... benzo[a]pyrene decreases expression ISO RGD:736560 6480464 Benzo(a)pyrene results in decreased expression of EPHX1 mRNA CTD PMID:32234424 benzo[a]pyrene increases methylation ISO RGD:736560 6480464 Benzo(a)pyrene results in increased methylation of EPHX1 3' UTR, Benzo(a)pyrene results in increased methylation of EPHX1 5' UTR CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:736560 6480464 Benzo(a)pyrene results in decreased methylation of EPHX1 exon, Benzo(a)pyrene results in decreased methylation of EPHX1 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7 more ... CTD PMID:24025706 , PMID:24530354 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA CTD PMID:24025706 benzo[a]pyrene increases activity ISO RGD:736560 6480464 Benzo(a)pyrene results in increased activity of EPHX1 protein CTD PMID:16484233 benzo[a]pyrene increases expression ISO RGD:10529 6480464 Benzo(a)pyrene metabolite results in increased expression of EPHX1 mRNA more ... CTD PMID:19770486 more ... benzo[a]pyrene increases expression ISO RGD:736560 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA CTD PMID:15735009 more ... benzo[a]pyrene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:22759596 more ... Benzo[a]pyrene-7,8-diol multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7, 8-dihydrodiol CTD PMID:24530354 Benzo[a]pyrene-7,8-oxide multiple interactions EXP 6480464 CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7, 8-oxide] CTD PMID:12051674 benzo[b]fluoranthene increases expression ISO RGD:10529 6480464 benzo(b)fluoranthene results in increased expression of EPHX1 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA CTD PMID:27858113 benzo[c]phenanthrene multiple interactions ISO RGD:10529 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 benzo[c]phenanthrene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 benzothiazole increases expression EXP 6480464 benzothiazole results in increased expression of EPHX1 mRNA CTD PMID:8951341 beta-naphthoflavone increases expression ISO RGD:736560 6480464 beta-Naphthoflavone results in increased expression of EPHX1 mRNA CTD PMID:22258563 beta-naphthoflavone increases expression ISO RGD:10529 6480464 beta-Naphthoflavone results in increased expression of EPHX1 mRNA CTD PMID:23994337 beta-naphthoflavone decreases activity ISO RGD:10529 6480464 beta-Naphthoflavone results in decreased activity of EPHX1 protein CTD PMID:3621371 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of EPHX1 mRNA CTD PMID:23292798 bifenthrin increases expression ISO RGD:10529 6480464 bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 bis(2-ethylhexyl) phthalate increases expression ISO RGD:10529 6480464 Diethylhexyl Phthalate results in increased expression of EPHX1 mRNA, Diethylhexyl Phthalate results in increased expression of EPHX1 protein CTD PMID:19850644 , PMID:3318844 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bis(2-ethylhexyl) phthalate increases activity ISO RGD:10529 6480464 Diethylhexyl Phthalate results in increased activity of EPHX1 protein CTD PMID:3621371 bis(2-ethylhexyl) phthalate decreases activity EXP 6480464 Diethylhexyl Phthalate results in decreased activity of EPHX1 protein CTD PMID:10528994 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EPHX1 mRNA, bisphenol A results in decreased expression of EPHX1 protein CTD PMID:24752506 more ... bisphenol A decreases expression ISO RGD:736560 6480464 bisphenol A results in decreased expression of EPHX1 protein CTD PMID:31675489 bisphenol A increases methylation ISO RGD:736560 6480464 bisphenol A results in increased methylation of EPHX1 gene CTD PMID:31601247 bisphenol A decreases expression ISO RGD:10529 6480464 bisphenol A results in decreased expression of EPHX1 mRNA CTD PMID:32156529 , PMID:33221593 bisphenol A increases expression ISO RGD:736560 6480464 bisphenol A results in increased expression of EPHX1 mRNA, bisphenol A results in increased expression of EPHX1 protein CTD PMID:29275510 , PMID:33376534 bisphenol A affects expression ISO RGD:736560 6480464 bisphenol A affects the expression of EPHX1 mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO RGD:10529 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A multiple interactions ISO RGD:736560 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of EPHX1 gene, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EPHX1 mRNA CTD PMID:28628672 , PMID:31601247 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EPHX1 mRNA, bisphenol A results in increased expression of EPHX1 protein CTD PMID:27208089 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EPHX1 mRNA, bisphenol A affects the expression of EPHX1 protein CTD PMID:25181051 more ... bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA, [bisphenol A co-treated with Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:26496021 , PMID:36041667 bisphenol A affects response to substance ISO RGD:736560 6480464 EPHX1 polymorphism affects the susceptibility to bisphenol A CTD PMID:26922413 Bisphenol B increases expression ISO RGD:736560 6480464 bisphenol B results in increased expression of EPHX1 protein CTD PMID:34186270 bisphenol F multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EPHX1 mRNA CTD PMID:28628672 bisphenol F increases expression ISO RGD:736560 6480464 bisphenol F results in increased expression of EPHX1 protein CTD PMID:34186270 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA CTD PMID:36041667 bisphenol F multiple interactions ISO RGD:10529 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EPHX1 mRNA CTD PMID:30951980 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of EPHX1 mRNA CTD PMID:12628495 more ... buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of EPHX1 mRNA CTD PMID:24136188 buta-1,3-diene increases response to substance ISO RGD:736560 6480464 EPHX1 5' UTR polymorphism results in increased susceptibility to 1 more ... CTD PMID:11238181 more ... buta-1,3-diene increases response to substance ISO RGD:10529 6480464 EPHX1 gene mutant form results in increased susceptibility to 1, 3-butadiene CTD PMID:12929123 , PMID:16730686 buta-1,3-diene multiple interactions ISO RGD:736560 6480464 GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1 more ... CTD PMID:11238181 butanal decreases expression ISO RGD:736560 6480464 butyraldehyde results in decreased expression of EPHX1 mRNA CTD PMID:26079696 butylated hydroxyanisole increases activity ISO RGD:10529 6480464 Butylated Hydroxyanisole results in increased activity of EPHX1 protein CTD PMID:3621371 butyric acid multiple interactions ISO RGD:736560 6480464 Benzo(a)pyrene affects the reaction [Butyric Acid results in decreased expression of EPHX1 mRNA] CTD PMID:30439556 butyric acid decreases expression ISO RGD:736560 6480464 Butyric Acid results in decreased expression of EPHX1 mRNA CTD PMID:30439556 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of EPHX1 mRNA CTD PMID:17327699 cadmium dichloride decreases expression ISO RGD:10529 6480464 Cadmium Chloride results in decreased expression of EPHX1 mRNA CTD PMID:20061341 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of EPHX1 mRNA CTD PMID:25993096 cadmium dichloride increases expression ISO RGD:10529 6480464 Cadmium Chloride results in increased expression of EPHX1 mRNA CTD PMID:24982889 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of EPHX1 mRNA CTD PMID:17327699 cannabidiol increases expression ISO RGD:10529 6480464 Cannabidiol results in increased expression of EPHX1 mRNA CTD PMID:27256343 captan increases expression ISO RGD:10529 6480464 Captan results in increased expression of EPHX1 mRNA CTD PMID:31558096 carbamazepine increases expression ISO RGD:736560 6480464 Carbamazepine results in increased expression of EPHX1 mRNA CTD PMID:17112801 carbamazepine affects response to substance ISO RGD:736560 6480464 EPHX1 gene SNP affects the susceptibility to Carbamazepine, EPHX1 protein affects the susceptibility to Carbamazepine CTD PMID:19620853 , PMID:26555147 carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of EPHX1 mRNA CTD PMID:17381134 carbamazepine-10,11-epoxide multiple interactions ISO RGD:736560 6480464 [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10 more ... CTD PMID:15692831 carbon nanotube decreases expression ISO RGD:10529 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 carmustine decreases expression ISO RGD:736560 6480464 Carmustine results in decreased expression of EPHX1 mRNA CTD PMID:15980968 catechol multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol] CTD PMID:8211999 CGP 52608 multiple interactions ISO RGD:736560 6480464 CGP 52608 promotes the reaction [RORA protein binds to EPHX1 gene] CTD PMID:28238834 chenodeoxycholic acid decreases expression ISO RGD:736560 6480464 Chenodeoxycholic Acid results in decreased expression of EPHX1 mRNA CTD PMID:27174168 chenodeoxycholic acid multiple interactions ISO RGD:736560 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons more ... CTD PMID:30744511 chloroprene increases expression ISO RGD:10529 6480464 Chloroprene results in increased expression of EPHX1 mRNA CTD PMID:23125180 chrysene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:27858113 , PMID:8961944 chrysene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of chrysene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene] CTD PMID:8961944 ciguatoxin CTX1B affects expression ISO RGD:10529 6480464 Ciguatoxins affects the expression of EPHX1 mRNA CTD PMID:18353800 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:18246545 cisplatin multiple interactions ISO RGD:736560 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of EPHX1 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:736560 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:10529 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:21151649 , PMID:21382384 cisplatin affects expression EXP 6480464 Cisplatin affects the expression of EPHX1 mRNA CTD PMID:18246545 clofibrate decreases activity EXP 6480464 Clofibrate results in decreased activity of EPHX1 protein CTD PMID:10528994 clofibrate increases activity ISO RGD:10529 6480464 Clofibrate results in increased activity of EPHX1 protein CTD PMID:3621371 clofibrate increases expression ISO RGD:10529 6480464 Clofibrate results in increased expression of EPHX1 protein CTD PMID:3318844 , PMID:4049385 clomipramine affects expression EXP 6480464 Clomipramine affects the expression of EPHX1 mRNA CTD PMID:18355885 clonazepam increases activity EXP 6480464 Clonazepam results in increased activity of EPHX1 protein CTD PMID:1372805 clotrimazole increases activity EXP 6480464 Clotrimazole results in increased activity of EPHX1 protein CTD PMID:1372805 cobalt dichloride increases expression ISO RGD:736560 6480464 cobaltous chloride results in increased expression of EPHX1 mRNA CTD PMID:19320972 cobalt dichloride decreases expression ISO RGD:736560 6480464 cobaltous chloride results in decreased expression of EPHX1 mRNA CTD PMID:19376846 colforsin daropate hydrochloride affects expression ISO RGD:736560 6480464 Colforsin affects the expression of EPHX1 mRNA CTD PMID:20726872 colforsin daropate hydrochloride multiple interactions ISO RGD:736560 6480464 Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA] CTD PMID:20726872 copper atom multiple interactions ISO RGD:736560 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 copper(0) multiple interactions ISO RGD:736560 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 copper(II) sulfate decreases expression ISO RGD:736560 6480464 Copper Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:19549813 coumarin increases expression ISO RGD:10529 6480464 coumarin results in increased expression of EPHX1 mRNA CTD PMID:17311802 CU-O LINKAGE decreases expression ISO RGD:736560 6480464 cupric oxide results in decreased expression of EPHX1 mRNA CTD PMID:32285662 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of EPHX1 mRNA CTD PMID:27523638 cyclophosphamide affects expression EXP 6480464 Cyclophosphamide affects the expression of EPHX1 mRNA CTD PMID:18246545 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of EPHX1 mRNA CTD PMID:18246545 cyclosporin A decreases expression ISO RGD:736560 6480464 Cyclosporine results in decreased expression of EPHX1 mRNA CTD PMID:20106945 , PMID:27989131 cyclosporin A multiple interactions ISO RGD:736560 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:32152650 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of EPHX1 mRNA CTD PMID:22528246 cyproconazole increases expression ISO RGD:10529 6480464 cyproconazole results in increased expression of EPHX1 mRNA CTD PMID:22334560 cyproconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of EPHX1 mRNA CTD PMID:29038839 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of EPHX1 mRNA CTD PMID:29038839 DDT increases activity EXP 6480464 DDT results in increased activity of EPHX1 protein CTD PMID:1372805 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of EPHX1 mRNA CTD PMID:32679240 decabromodiphenyl ether increases expression ISO RGD:736560 6480464 decabromobiphenyl ether results in increased expression of EPHX1 protein CTD PMID:31675489 deoxycholic acid multiple interactions ISO RGD:736560 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 deoxynivalenol decreases expression ISO RGD:10529 6480464 deoxynivalenol results in decreased expression of EPHX1 mRNA CTD PMID:15371230 dexamethasone multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 dextran sulfate decreases expression ISO RGD:10529 6480464 Dextran Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:35093514 Diallyl sulfide increases activity EXP 6480464 allyl sulfide results in increased activity of EPHX1 protein CTD PMID:1372805 Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of EPHX1 mRNA CTD PMID:19695238 diallyl trisulfide increases expression EXP 6480464 diallyl trisulfide results in increased expression of EPHX1 mRNA CTD PMID:20650352 diarsenic trioxide decreases expression ISO RGD:736560 6480464 Arsenic Trioxide results in decreased expression of EPHX1 mRNA CTD PMID:17547211 diazinon decreases expression ISO RGD:10529 6480464 Diazinon results in decreased expression of EPHX1 mRNA CTD PMID:17311802 dibenz[a,h]anthracene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1 more ... CTD PMID:8961944 dibenz[a,h]anthracene increases expression ISO RGD:10529 6480464 1 more ... CTD PMID:26377693 dibenz[a,h]anthracene multiple interactions ISO RGD:10529 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1 more ... CTD PMID:8961944 dibenzofurans increases expression ISO RGD:10529 6480464 Dibenzofurans results in increased expression of EPHX1 mRNA CTD PMID:34254344 dibenzoylmethane increases activity ISO RGD:10529 6480464 dibenzoylmethane results in increased activity of EPHX1 protein CTD PMID:3621371 dibenzoylmethane multiple interactions ISO RGD:10529 6480464 [sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA CTD PMID:17942926 dibenzoylmethane increases expression ISO RGD:10529 6480464 dibenzoylmethane results in increased expression of EPHX1 mRNA CTD PMID:17942926 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of EPHX1 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO RGD:10529 6480464 Dibutyl Phthalate results in decreased expression of EPHX1 mRNA CTD PMID:17361019 dichloroacetic acid increases expression ISO RGD:10529 6480464 Dichloroacetic Acid results in increased expression of EPHX1 mRNA CTD PMID:28962523 diclofenac decreases expression EXP 6480464 Diclofenac results in decreased expression of EPHX1 mRNA CTD PMID:17202759 dieldrin multiple interactions ISO RGD:10529 6480464 Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 diepoxybutane affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to diepoxybutane CTD PMID:15036125 diepoxybutane increases response to substance ISO RGD:10529 6480464 EPHX1 gene mutant form results in increased susceptibility to diepoxybutane CTD PMID:12929123 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of EPHX1 mRNA CTD PMID:15890375 Dihydroxycarbazepine multiple interactions ISO RGD:736560 6480464 [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10 more ... CTD PMID:15692831 dioxygen multiple interactions EXP 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of EPHX1 mRNA], [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of EPHX1 mRNA CTD PMID:33729688 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions ISO RGD:736560 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 diuron increases expression EXP 6480464 Diuron results in increased expression of EPHX1 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:736560 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 doxorubicin increases expression ISO RGD:736560 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:15205334 , PMID:29803840 doxorubicin increases expression ISO RGD:10529 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:21382384 , PMID:22016648 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:19915844 endosulfan affects expression EXP 6480464 Endosulfan affects the expression of EPHX1 mRNA CTD PMID:29391264 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of EPHX1 mRNA CTD PMID:25182419 epoxiconazole decreases expression ISO RGD:10529 6480464 epoxiconazole results in decreased expression of EPHX1 mRNA CTD PMID:35436446 epoxiconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of EPHX1 mRNA CTD PMID:29038839 epoxiconazole increases expression ISO RGD:10529 6480464 epoxiconazole results in increased expression of EPHX1 mRNA CTD PMID:22334560 Erucin increases expression EXP 6480464 erucin results in increased expression of EPHX1 protein CTD PMID:21132492 estradiol increases activity EXP 152998935 estradiol increases Ephx1 enzyme activity in rat liver microsomes RGD ethanol increases expression EXP 6480464 Ethanol results in increased expression of EPHX1 mRNA CTD PMID:23273579 ethanol multiple interactions ISO RGD:10529 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of EPHX1 mRNA CTD PMID:30517762 ethoxyquin increases expression EXP 6480464 Ethoxyquin results in increased expression of EPHX1 mRNA CTD PMID:19695238 etoposide increases expression ISO RGD:10529 6480464 Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384 , PMID:25270620 felbamate increases expression EXP 6480464 felbamate results in increased expression of EPHX1 mRNA CTD PMID:17381134 fenamidone increases expression ISO RGD:10529 6480464 fenamidone results in increased expression of EPHX1 mRNA CTD PMID:27029645 fenvalerate increases activity EXP 6480464 fenvalerate metabolite results in increased activity of EPHX1 protein CTD PMID:10630566 finasteride increases expression EXP 6480464 Finasteride results in increased expression of EPHX1 mRNA CTD PMID:24136188 fipronil increases expression EXP 6480464 fipronil results in increased expression of EPHX1 mRNA CTD PMID:23962444 flutamide increases expression EXP 6480464 Flutamide results in increased expression of EPHX1 mRNA CTD PMID:24136188 folpet increases expression ISO RGD:10529 6480464 folpet results in increased expression of EPHX1 mRNA CTD PMID:31558096 fulvestrant multiple interactions ISO RGD:736560 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of EPHX1 gene CTD PMID:31601247 fumonisin B1 increases expression ISO RGD:10529 6480464 fumonisin B1 results in increased expression of EPHX1 mRNA CTD PMID:16221962 furan increases methylation EXP 6480464 furan results in increased methylation of EPHX1 gene CTD PMID:22079235 furan increases expression EXP 6480464 furan results in increased expression of EPHX1 mRNA CTD PMID:25539665 , PMID:26194646 furan increases expression ISO RGD:10529 6480464 furan results in increased expression of EPHX1 mRNA CTD PMID:24183702 genistein increases expression ISO RGD:736560 6480464 Genistein results in increased expression of EPHX1 mRNA CTD PMID:18847459 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of EPHX1 mRNA CTD PMID:33387578 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of EPHX1 mRNA CTD PMID:24136188 glucoerucin increases expression EXP 6480464 glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 glucoerucin(1-) increases expression EXP 6480464 glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 glucoraphanin increases expression EXP 6480464 glucoraphanin results in increased expression of EPHX1 protein CTD PMID:21132492 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of EPHX1 mRNA CTD PMID:15345336 glycochenodeoxycholic acid multiple interactions ISO RGD:736560 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 glycocholic acid multiple interactions ISO RGD:736560 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 glycodeoxycholic acid multiple interactions ISO RGD:736560 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 gold atom increases expression ISO RGD:736560 6480464 Gold analog results in increased expression of EPHX1 mRNA CTD PMID:36057382 gold(0) increases expression ISO RGD:736560 6480464 Gold analog results in increased expression of EPHX1 mRNA CTD PMID:36057382 Heliotrine increases expression EXP 6480464 heliotrine results in increased expression of EPHX1 mRNA CTD PMID:32419051 Heptachlor epoxide multiple interactions ISO RGD:10529 6480464 Heptachlor Epoxide promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of EPHX1 mRNA CTD PMID:21905055 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of EPHX1 mRNA CTD PMID:15159207 HT-2 toxin increases expression ISO RGD:736560 6480464 HT-2 toxin results in increased expression of EPHX1 mRNA CTD PMID:22982764 hydrogen peroxide increases expression ISO RGD:10529 6480464 Hydrogen Peroxide results in increased expression of EPHX1 mRNA CTD PMID:21382384 hydroquinone multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone], EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 imipramine affects expression EXP 6480464 Imipramine affects the expression of EPHX1 mRNA CTD PMID:18355885 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of EPHX1 mRNA CTD PMID:21396975 indometacin multiple interactions ISO RGD:736560 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 inulin multiple interactions ISO RGD:10529 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of EPHX1 mRNA CTD PMID:36331819 ivermectin decreases expression ISO RGD:736560 6480464 Ivermectin results in decreased expression of EPHX1 protein CTD PMID:32959892 ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of EPHX1 mRNA CTD PMID:18355885 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of EPHX1 mRNA CTD PMID:37077353 kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA, [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNA CTD PMID:18544905 L-ascorbic acid multiple interactions ISO RGD:736560 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 lanosterol multiple interactions ISO RGD:10529 6480464 Lanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] CTD PMID:2043152 lead(0) affects expression ISO RGD:736560 6480464 Lead affects the expression of EPHX1 mRNA CTD PMID:28903495 levofloxacin decreases expression EXP 6480464 Levofloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 lithocholic acid multiple interactions ISO RGD:10529 6480464 [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA CTD PMID:20359477 m-xylene increases expression ISO RGD:736560 6480464 3-xylene results in increased expression of EPHX1 mRNA CTD PMID:33269480 malathion decreases expression ISO RGD:10529 6480464 Malathion results in decreased expression of EPHX1 mRNA CTD PMID:17311802 mandelic acid multiple interactions ISO RGD:736560 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 medroxyprogesterone acetate multiple interactions ISO RGD:736560 6480464 ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein] CTD PMID:20383792 medroxyprogesterone acetate increases expression ISO RGD:736560 6480464 Medroxyprogesterone Acetate results in increased expression of EPHX1 mRNA, Medroxyprogesterone Acetate results in increased expression of EPHX1 protein CTD PMID:20383792 menadione increases expression ISO RGD:10529 6480464 Vitamin K 3 results in increased expression of EPHX1 mRNA CTD PMID:21382384 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of EPHX1 mRNA CTD PMID:32599119 methamphetamine increases expression ISO RGD:10529 6480464 Methamphetamine results in increased expression of EPHX1 mRNA, Methamphetamine results in increased expression of EPHX1 protein CTD PMID:26307267 , PMID:31422080 methamphetamine multiple interactions ISO RGD:10529 6480464 EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein] more ... CTD PMID:31422080 methamphetamine increases methylation ISO RGD:10529 6480464 Methamphetamine results in increased methylation of EPHX1 promoter CTD PMID:26307267 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of EPHX1 mRNA CTD PMID:15890375 methyl methanesulfonate increases expression ISO RGD:10529 6480464 Methyl Methanesulfonate results in increased expression of EPHX1 mRNA CTD PMID:21382384 methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons more ... CTD PMID:30744511 mitomycin C increases expression ISO RGD:10529 6480464 Mitomycin results in increased expression of EPHX1 mRNA CTD PMID:21382384 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of EPHX1 mRNA CTD PMID:12706301 muconic acid multiple interactions ISO RGD:736560 6480464 [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 N,N'-diphenylthiourea increases expression EXP 6480464 diphenylthiourea results in increased expression of EPHX1 mRNA, diphenylthiourea results in increased expression of EPHX1 protein CTD PMID:10190572 N,N-diethyl-m-toluamide increases expression ISO RGD:736560 6480464 DEET results in increased expression of EPHX1 mRNA CTD PMID:27091632 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:10529 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX1 mRNA CTD PMID:20061341 N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:15954086 N-methyl-N-nitrosourea increases expression ISO RGD:10529 6480464 Methylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:21382384 N-Methylolacrylamide decreases expression ISO RGD:10529 6480464 N-methylolacrylamide results in decreased expression of EPHX1 mRNA CTD PMID:17311802 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA more ... CTD PMID:18544905 more ... N-nitrosodiethylamine increases expression ISO RGD:10529 6480464 Diethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:17854601 , PMID:21607683 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:17602206 more ... N-nitrosodiethylamine multiple interactions ISO RGD:10529 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPHX1 mRNA] CTD PMID:17854601 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:14600272 , PMID:15890375 naphthalene increases expression ISO RGD:736560 6480464 naphthalene results in increased expression of EPHX1 mRNA CTD PMID:20500019 naphthalene increases response to substance ISO RGD:10529 6480464 EPHX1 results in increased susceptibility to naphthalene CTD PMID:26840748 naphthalene increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of naphthalene CTD PMID:18363382 , PMID:26840748 naphthalene multiple interactions ISO RGD:10529 6480464 [EPHX1 protein results in increased metabolism of naphthalene] which results in increased chemical synthesis of 1 more ... CTD PMID:18363382 , PMID:26840748 naphthalene-1,5-diamine affects expression ISO RGD:10529 6480464 1, 5-naphthalenediamine affects the expression of EPHX1 mRNA CTD PMID:17114358 naphthalene-1,5-diamine increases expression ISO RGD:10529 6480464 1, 5-naphthalenediamine results in increased expression of EPHX1 mRNA CTD PMID:17311802 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of EPHX1 mRNA CTD PMID:24136188 nefazodone decreases expression ISO RGD:736560 6480464 nefazodone results in decreased expression of EPHX1 mRNA CTD PMID:32152650 nefazodone multiple interactions ISO RGD:736560 6480464 [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:32152650 nickel atom decreases expression ISO RGD:736560 6480464 Nickel results in decreased expression of EPHX1 mRNA CTD PMID:25583101 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of EPHX1 mRNA CTD PMID:24136188 nimesulide decreases glutathionylation ISO RGD:736560 6480464 EPHX1 protein results in decreased glutathionylation of nimesulide CTD PMID:26524229 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of EPHX1 mRNA CTD PMID:33484710 ochratoxin A increases expression ISO RGD:736560 6480464 ochratoxin A results in increased expression of EPHX1 mRNA CTD PMID:32905824 organoselenium compound increases activity ISO RGD:10529 6480464 Organoselenium Compounds results in increased activity of EPHX1 protein CTD PMID:17163488 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of EPHX1 mRNA CTD PMID:25729387 oxirane affects metabolic processing ISO RGD:736560 6480464 EPHX1 protein affects the metabolism of Ethylene Oxide CTD PMID:11437638 oxirane affects metabolic processing EXP 6480464 EPHX1 protein affects the metabolism of Ethylene Oxide CTD PMID:11437638 ozone decreases expression ISO RGD:10529 6480464 Ozone results in decreased expression of EPHX1 mRNA CTD PMID:12763052 ozone multiple interactions ISO RGD:10529 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EPHX1 mRNA CTD PMID:34911549 p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of EPHX1 mRNA CTD PMID:27638505 paracetamol affects expression ISO RGD:10529 6480464 Acetaminophen affects the expression of EPHX1 mRNA CTD PMID:15606129 , PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EPHX1 mRNA CTD PMID:30723492 , PMID:33387578 paracetamol increases expression ISO RGD:736560 6480464 Acetaminophen results in increased expression of EPHX1 mRNA CTD PMID:22230336 paracetamol multiple interactions ISO RGD:10529 6480464 [Acetaminophen results in increased activity of and results in increased localization of NFE2L2 protein] which results in increased expression of EPHX1 mRNA CTD PMID:15122755 pentachloronitrobenzene increases expression ISO RGD:10529 6480464 quintozene results in increased expression of EPHX1 mRNA CTD PMID:17311802 pentachlorophenol increases expression ISO RGD:10529 6480464 Pentachlorophenol results in increased expression of EPHX1 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:10529 6480464 [Dietary Fats co-treated with perfluorooctane sulfonic acid] results in increased expression of EPHX1 mRNA more ... CTD PMID:32979393 , PMID:36331819 perfluorooctane-1-sulfonic acid increases expression ISO RGD:736560 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:27153767 perfluorooctane-1-sulfonic acid increases expression ISO RGD:10529 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA, perfluorooctane sulfonic acid results in increased expression of EPHX1 protein CTD PMID:20936131 , PMID:32979393 perfluorooctane-1-sulfonic acid affects expression ISO RGD:10529 6480464 perfluorooctane sulfonic acid affects the expression of EPHX1 mRNA CTD PMID:19429403 perfluorooctanoic acid affects expression ISO RGD:10529 6480464 perfluorooctanoic acid affects the expression of EPHX1 mRNA CTD PMID:18281256 , PMID:19429403 perfluorooctanoic acid decreases expression ISO RGD:10529 6480464 perfluorooctanoic acid results in decreased expression of EPHX1 protein CTD PMID:28126411 perfluorooctanoic acid multiple interactions ISO RGD:10529 6480464 [perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of EPHX1 mRNA CTD PMID:23626681 perfluorooctanoic acid increases expression ISO RGD:10529 6480464 perfluorooctanoic acid results in increased expression of EPHX1 mRNA CTD PMID:23626681 permethrin increases expression ISO RGD:10529 6480464 Permethrin results in increased expression of EPHX1 mRNA CTD PMID:30629241 phenethyl isothiocyanate increases expression EXP 6480464 phenethyl isothiocyanate results in increased expression of EPHX1 protein CTD PMID:21132492 phenobarbital multiple interactions ISO RGD:10529 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of EPHX1 mRNA], NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of EPHX1 mRNA] CTD PMID:19482888 , PMID:19850644 phenobarbital decreases expression ISO RGD:10529 6480464 Phenobarbital results in decreased expression of EPHX1 protein CTD PMID:35881160 phenobarbital increases expression ISO RGD:736560 6480464 Phenobarbital results in increased expression of EPHX1 mRNA, Phenobarbital results in increased expression of EPHX1 protein CTD PMID:22258563 more ... phenobarbital affects expression ISO RGD:10529 6480464 Phenobarbital affects the expression of EPHX1 mRNA CTD PMID:23091169 phenobarbital increases expression ISO RGD:10529 6480464 Phenobarbital results in increased expression of EPHX1 mRNA CTD PMID:19482888 more ... phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of EPHX1 mRNA, Phenobarbital results in increased expression of EPHX1 protein CTD PMID:11328961 more ... phenobarbital affects expression ISO RGD:736560 6480464 Phenobarbital affects the expression of EPHX1 mRNA CTD PMID:19159669 phenobarbital increases activity ISO RGD:10529 6480464 Phenobarbital results in increased activity of EPHX1 protein CTD PMID:3621371 phenobarbital multiple interactions EXP 6480464 [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of EPHX1 protein CTD PMID:20935162 phenol multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol] more ... CTD PMID:8211999 phenols increases expression ISO RGD:736560 6480464 Phenols results in increased expression of EPHX1 mRNA CTD PMID:23561572 phenylglyoxylic acid multiple interactions ISO RGD:736560 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 phenylmercury acetate increases expression ISO RGD:736560 6480464 Phenylmercuric Acetate results in increased expression of EPHX1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736560 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 phenytoin affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Phenytoin CTD PMID:19952982 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of EPHX1 mRNA CTD PMID:17381134 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased expression of EPHX1 mRNA CTD PMID:12376462 phlorizin decreases expression ISO RGD:10529 6480464 Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate decreases expression ISO RGD:736560 6480464 Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein CTD PMID:24704207 phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of EPHX1 mRNA, phosphoramide mustard results in increased expression of EPHX1 protein CTD PMID:25070981 pimecrolimus multiple interactions ISO RGD:736560 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA] CTD PMID:29356861 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of EPHX1 mRNA CTD PMID:15890375 , PMID:22484513 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of EPHX1 mRNA CTD PMID:19162173 pirinixic acid increases expression ISO RGD:10529 6480464 pirinixic acid results in increased expression of EPHX1 mRNA CTD PMID:15375163 more ... pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of EPHX1 mRNA CTD PMID:15890375 pirinixic acid multiple interactions ISO RGD:10529 6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of EPHX1 mRNA] CTD PMID:16221962 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:10529 6480464 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA CTD PMID:20359477 , PMID:27413110 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:10529 6480464 [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA CTD PMID:20359477 propiconazole affects expression EXP 6480464 propiconazole affects the expression of EPHX1 mRNA CTD PMID:17383973 propiconazole increases expression ISO RGD:10529 6480464 propiconazole results in increased expression of EPHX1 mRNA CTD PMID:21278054 , PMID:22334560 propionamide decreases activity EXP 6480464 propionamide analog results in decreased activity of EPHX1 protein CTD PMID:18363382 propionamide decreases activity ISO RGD:10529 6480464 propionamide analog results in decreased activity of EPHX1 protein CTD PMID:18363382 propionamide multiple interactions ISO RGD:10529 6480464 [propionamide analog results in decreased activity of EPHX1 protein] which results in increased glutathionylation of naphthalene CTD PMID:18363382 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of EPHX1 mRNA CTD PMID:22431067 quartz decreases expression ISO RGD:736560 6480464 Quartz results in decreased expression of EPHX1 mRNA CTD PMID:27917503 quercetin multiple interactions ISO RGD:736560 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 quercetin increases expression EXP 6480464 Quercetin results in increased expression of EPHX1 mRNA CTD PMID:18095365 , PMID:21565894 resveratrol multiple interactions ISO RGD:736560 6480464 resveratrol promotes the reaction [Benzo(a)pyrene results in increased activity of EPHX1 protein] CTD PMID:16484233 resveratrol affects expression ISO RGD:10529 6480464 resveratrol affects the expression of EPHX1 mRNA CTD PMID:23525482 resveratrol increases expression ISO RGD:736560 6480464 resveratrol results in increased expression of EPHX1 mRNA, resveratrol results in increased expression of EPHX1 protein CTD PMID:11279601 , PMID:18089832 rifampicin increases expression ISO RGD:736560 6480464 Rifampin results in increased expression of EPHX1 mRNA CTD PMID:22258563 more ... rifampicin multiple interactions ISO RGD:736560 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA] CTD PMID:29356861 rotenone increases expression ISO RGD:10529 6480464 Rotenone results in increased expression of EPHX1 mRNA CTD PMID:22016648 rotenone increases expression EXP 6480464 Rotenone results in increased expression of EPHX1 mRNA CTD PMID:28374803 SB 431542 multiple interactions ISO RGD:736560 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of EPHX1 mRNA CTD PMID:15967596 silicon dioxide decreases expression ISO RGD:736560 6480464 Silicon Dioxide analog results in decreased expression of EPHX1 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO RGD:736560 6480464 Silicon Dioxide results in increased expression of EPHX1 mRNA CTD PMID:27917503 silver atom multiple interactions ISO RGD:736560 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 silver atom increases expression ISO RGD:10529 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 silver atom increases expression ISO RGD:736560 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 silver(0) multiple interactions ISO RGD:736560 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 silver(0) increases expression ISO RGD:10529 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:736560 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 sodium arsenite increases expression ISO RGD:736560 6480464 sodium arsenite results in increased expression of EPHX1 mRNA CTD PMID:25493608 sodium arsenite multiple interactions ISO RGD:736560 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 sodium dichromate decreases expression ISO RGD:10529 6480464 sodium bichromate results in decreased expression of EPHX1 mRNA CTD PMID:22155349 stilbene oxide multiple interactions ISO RGD:10529 6480464 araldite promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide analog] more ... CTD PMID:2043152 stilbene oxide increases metabolic processing ISO RGD:10529 6480464 EPHX1 protein results in increased metabolism of stilbene oxide, EPHX1 protein results in increased metabolism of stilbene oxide analog CTD PMID:2043152 stilbenoid increases activity ISO RGD:10529 6480464 Stilbenes results in increased activity of EPHX1 protein CTD PMID:3621371 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of EPHX1 protein CTD PMID:19634143 streptozocin multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] CTD PMID:19634143 styrene increases expression EXP 6480464 Styrene results in increased expression of EPHX1 mRNA CTD PMID:16418063 styrene decreases response to substance ISO RGD:10529 6480464 EPHX1 protein results in decreased susceptibility to Styrene CTD PMID:22386858 styrene affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Styrene CTD PMID:14751678 styrene oxide multiple interactions EXP 6480464 CYP1A1 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] more ... CTD PMID:12051674 styrene oxide multiple interactions ISO RGD:736560 6480464 EPHX1 protein affects the metabolism of and results in decreased activity of styrene oxide CTD PMID:12694745 styrene oxide affects hydrolysis ISO RGD:736560 6480464 EPHX1 protein affects the hydrolysis of styrene oxide CTD PMID:11076696 sulfasalazine increases expression ISO RGD:10529 6480464 Sulfasalazine results in increased expression of EPHX1 mRNA CTD PMID:22016648 , PMID:31830553 sulforaphane increases expression ISO RGD:10529 6480464 sulforaphane results in increased expression of EPHX1 mRNA CTD PMID:17942926 sulforaphane increases expression ISO RGD:736560 6480464 sulforaphane results in increased expression of EPHX1 exon more ... CTD PMID:24704207 , PMID:31838189 sulforaphane multiple interactions ISO RGD:736560 6480464 sulforaphane promotes the reaction [NFE2L2 protein binds to EPHX1 enhancer] CTD PMID:24704207 sulforaphane multiple interactions ISO RGD:10529 6480464 [sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA CTD PMID:17942926 sunitinib decreases expression ISO RGD:736560 6480464 Sunitinib results in decreased expression of EPHX1 mRNA CTD PMID:31533062 tamoxifen affects expression ISO RGD:736560 6480464 Tamoxifen affects the expression of EPHX1 mRNA CTD PMID:14699072 tamoxifen affects expression ISO RGD:10529 6480464 Tamoxifen affects the expression of EPHX1 mRNA CTD PMID:17555576 tert-butyl ethyl ether increases expression EXP 6480464 ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 tert-butyl hydroperoxide increases expression ISO RGD:10529 6480464 tert-Butylhydroperoxide results in increased expression of EPHX1 mRNA CTD PMID:21382384 testosterone increases expression ISO RGD:10529 6480464 Testosterone deficiency results in increased expression of EPHX1 mRNA CTD PMID:33848595 tetrachloromethane decreases expression ISO RGD:10529 6480464 Carbon Tetrachloride results in decreased expression of EPHX1 mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO RGD:10529 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of EPHX1 mRNA CTD PMID:30517762 tetrachloromethane multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA], thymoquinone inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA] CTD PMID:21994235 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of EPHX1 mRNA CTD PMID:21994235 tetracycline decreases expression ISO RGD:10529 6480464 Tetracycline results in decreased expression of EPHX1 mRNA CTD PMID:24489787 Tetramethylthiourea increases expression EXP 6480464 tetramethylthiourea results in increased expression of EPHX1 mRNA, tetramethylthiourea results in increased expression of EPHX1 protein CTD PMID:10190572 tetraphene multiple interactions ISO RGD:10529 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:27858113 , PMID:8961944 tetraphene increases expression ISO RGD:10529 6480464 benz(a)anthracene results in increased expression of EPHX1 protein CTD PMID:2208584 tetraphene multiple interactions ISO RGD:736560 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benz(a)anthracene], EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene] CTD PMID:8961944 thiazoles increases expression EXP 6480464 Thiazoles results in increased expression of EPHX1 mRNA CTD PMID:8951341 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of EPHX1 mRNA CTD PMID:28943392 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of EPHX1 mRNA CTD PMID:34492290 thymoquinone multiple interactions EXP 6480464 thymoquinone inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA] CTD PMID:21994235 titanium dioxide decreases expression ISO RGD:10529 6480464 titanium dioxide results in decreased expression of EPHX1 mRNA CTD PMID:23557971 more ... topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of EPHX1 mRNA CTD PMID:33387578 Tridiphane multiple interactions ISO RGD:10529 6480464 tridiphane promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of EPHX1 mRNA CTD PMID:30589522 tris(2-butoxyethyl) phosphate affects expression ISO RGD:736560 6480464 tris(2-butoxyethyl) phosphate affects the expression of EPHX1 mRNA CTD PMID:29024780 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of EPHX1 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:736560 6480464 Valproic Acid results in decreased methylation of EPHX1 gene CTD PMID:29154799 , PMID:29501571 valproic acid decreases expression ISO RGD:736560 6480464 Valproic Acid results in decreased expression of EPHX1 mRNA CTD PMID:29501571 valproic acid multiple interactions ISO RGD:736560 6480464 Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA] CTD PMID:20726872 valproic acid increases expression ISO RGD:10529 6480464 Valproic Acid results in increased expression of EPHX1 mRNA CTD PMID:21427059 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of EPHX1 mRNA CTD PMID:17381134 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of EPHX1 mRNA CTD PMID:19015723 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of EPHX1 mRNA CTD PMID:23034163 vincristine decreases expression ISO RGD:10529 6480464 Vincristine results in decreased expression of EPHX1 mRNA CTD PMID:21382384 warfarin affects response to substance ISO RGD:736560 6480464 EPHX1 gene polymorphism affects the susceptibility to Warfarin more ... CTD PMID:15900282 more ... warfarin increases response to substance ISO RGD:736560 6480464 EPHX1 protein results in increased susceptibility to Warfarin CTD PMID:17496169 zinc atom increases expression EXP 6480464 Zinc results in increased expression of EPHX1 mRNA CTD PMID:17074742 zinc sulfate increases expression EXP 6480464 Zinc Sulfate results in increased expression of EPHX1 mRNA CTD PMID:17074742 zinc(0) increases expression EXP 6480464 Zinc results in increased expression of EPHX1 mRNA CTD PMID:17074742
