Ephx1 (epoxide hydrolase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ephx1 (epoxide hydrolase 1) Rattus norvegicus
Analyze
Symbol: Ephx1
Name: epoxide hydrolase 1
RGD ID: 2557
Description: Enables cis-stilbene-oxide hydrolase activity; enzyme binding activity; and epoxide hydrolase activity. Involved in several processes, including cellular response to glucocorticoid stimulus; diol biosynthetic process; and liver development. Located in intracellular membrane-bounded organelle and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1); PARTICIPATES IN carbamazepine pharmacokinetics pathway; phenytoin pharmacodynamics pathway; bile acid transport pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 1-nitropropane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epoxide hydratase; Epoxide hydrolase 1 (microsomal xenobiotic hydrolase; Epoxide hydrolase 1 (microsomal xenobiotic hydrolase); epoxide hydrolase 1, microsomal; epoxide hydrolase 1, microsomal (xenobiotic); liver microsomal xenobiotic epoxide hydrolase; mEH; MEH8; microsomal epoxide hydrolase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21392,714,315 - 92,744,124 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1392,714,315 - 92,790,235 (-)Ensembl
Rnor_6.01399,271,390 - 99,300,580 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,271,366 - 99,300,579 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,268,704 - 104,297,617 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,722,973 - 96,752,940 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11396,912,126 - 96,925,415 (-)NCBI
Celera1392,256,740 - 92,285,424 (-)NCBICelera
RH 3.4 Map13631.9RGD
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
(9R,10S)-9,10-epoxy-9,10-dihydrophenanthrene  (ISO)
(S)-mandelic acid  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,1-dichloroethene  (ISO)
1,2-dibromoethane  (ISO)
1,2-dihydronaphthalene-1,2-diol  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dioxane  (ISO)
1-benzofuran  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropropane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
1H-pyrazole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-tetramine  (EXP)
2,2-Bis(bromomethyl)propane-1,3-diol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-D  (ISO)
2,4-diaminotoluene  (EXP)
2,4-dinitrotoluene  (EXP,ISO)
2,6-diaminotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2,8-bis-Trifluoromethyl-4-quinoline carboxylic acid  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-nitro-p-phenylenediamine  (EXP)
2-nitrofluorene  (EXP)
2-nitropropane  (EXP)
2-Oxohexane  (EXP)
2-tert-butylhydroquinone  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,4-dihydrocoumarin  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP,ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-acetylaminofluorene  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitro-1,2-phenylenediamine  (EXP)
4-vinylcyclohexene dioxide  (EXP,ISO)
5,6alpha-epoxy-5alpha-cholestan-3beta-ol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
8,9-EET  (ISO)
8-Br-cAMP  (ISO)
9,10-epoxy-9,10-dihydrophenanthrene  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
amiodarone  (EXP)
amitriptyline  (EXP)
ammonium chloride  (EXP)
aniline  (ISO)
antimonite  (ISO)
aristolochic acid  (EXP,ISO)
Aroclor 1254  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
atazanavir sulfate  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
barbiturates  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[a]pyrene-7,8-diol  (EXP)
Benzo[a]pyrene-7,8-oxide  (EXP)
benzo[b]fluoranthene  (ISO)
benzo[c]phenanthrene  (ISO)
benzothiazole  (EXP)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
buspirone  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (EXP,ISO)
carbamazepine-10,11-epoxide  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
catechol  (EXP)
chenodeoxycholic acid  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
clomipramine  (EXP)
clonazepam  (EXP)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (EXP)
cyproconazole  (EXP,ISO)
DDT  (EXP)
decabromodiphenyl ether  (EXP)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzoylmethane  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
diclofenac  (EXP)
dieldrin  (ISO)
diepoxybutane  (ISO)
diethylstilbestrol  (EXP)
Dihydroxycarbazepine  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
epoxiconazole  (EXP,ISO)
Erucin  (EXP)
ethanol  (EXP,ISO)
ethoxyquin  (EXP)
etoposide  (ISO)
felbamate  (EXP)
fenamidone  (ISO)
fenvalerate  (EXP)
finasteride  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folpet  (ISO)
fumonisin B1  (ISO)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glucoerucin  (EXP)
glucoerucin(1-)  (EXP)
glucoraphanin  (EXP)
glutathione  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
Heliotrine  (EXP)
Heptachlor epoxide  (ISO)
Hexachloro-1,3-butadiene  (EXP)
hexachlorobenzene  (EXP)
HT-2 toxin  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (EXP)
imipramine  (EXP)
indole-3-methanol  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
kojic acid  (EXP)
L-ascorbic acid  (ISO)
lanosterol  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
levofloxacin  (EXP)
lithocholic acid  (ISO)
malathion  (ISO)
mandelic acid  (ISO)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mercury dichloride  (EXP)
methamphetamine  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
muconic acid  (ISO)
N,N'-diphenylthiourea  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-Methylolacrylamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
naphthalene  (ISO)
naphthalene-1,5-diamine  (ISO)
nefazodone  (EXP,ISO)
nickel atom  (ISO)
nimesulide  (EXP,ISO)
nitrofen  (EXP)
ochratoxin A  (ISO)
organoselenium compound  (ISO)
oxaliplatin  (EXP)
oxirane  (EXP,ISO)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
pentachloronitrobenzene  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP,ISO)
phenol  (EXP)
phenols  (ISO)
phenylglyoxylic acid  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (EXP,ISO)
PhIP  (EXP)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramide mustard  (EXP)
pimecrolimus  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (EXP,ISO)
propionamide  (EXP,ISO)
pyrazinecarboxamide  (EXP)
quartz  (ISO)
quercetin  (EXP,ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
stilbene oxide  (ISO)
stilbenoid  (ISO)
streptozocin  (EXP)
styrene  (EXP,ISO)
styrene oxide  (EXP,ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl ethyl ether  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
tetraphene  (ISO)
thiazoles  (EXP)
thioacetamide  (EXP)
thymoquinone  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
Tridiphane  (ISO)
triphenyl phosphate  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
trovafloxacin  (EXP)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (ISO)
warfarin  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Ahmadi A, etal., Biochem Biophys Res Commun. 2000 Mar 24;269(3):676-80.
2. Andrew AS, etal., Hum Genet. 2009 Jun;125(5-6):527-39. Epub 2009 Mar 1.
3. Arand M, etal., Biochem J. 1999 Jan 1;337 ( Pt 1):37-43.
4. Bell PA and Kasper CB, J Biol Chem. 1993 Jul 5;268(19):14011-7.
5. Bell PA, etal., Arch Biochem Biophys. 1990 Jun;279(2):363-9.
6. Bonaventure A, etal., Cancer Causes Control. 2012 Feb;23(2):329-45. doi: 10.1007/s10552-011-9882-9. Epub 2011 Dec 27.
7. Budhi A, etal., Int J Mol Med. 2003 Mar;11(3):321-9.
8. Chang HS, etal., Nutr Res. 2010 Jun;30(6):435-40.
9. Chappell S, etal., Eur Respir J. 2008 Oct;32(4):931-7. Epub 2008 Jul 9.
10. Chauhan PS, etal., DNA Cell Biol. 2011 Jan;30(1):39-46. doi: 10.1089/dna.2010.1092. Epub 2010 Aug 23.
11. Chauhan PS, etal., Environ Mol Mutagen. 2012 Oct;53(8):619-30. doi: 10.1002/em.21723. Epub 2012 Aug 29.
12. Christou M, etal., Carcinogenesis. 1989 Oct;10(10):1883-90.
13. Decker M, etal., J Lipid Res. 2012 Oct;53(10):2038-45. doi: 10.1194/jlr.M024448. Epub 2012 Jul 12.
14. Durie BG, etal., Leukemia. 2009 Oct;23(10):1913-9. doi: 10.1038/leu.2009.129. Epub 2009 Aug 6.
15. Falany CN, etal., J Biol Chem 1987 Apr 25;262(12):5924-30.
16. Farin FM, etal., Pharmacogenetics. 2001 Nov;11(8):703-8.
17. Friedberg T, etal., Carcinogenesis. 1994 Feb;15(2):171-5.
18. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
19. GOA data from the GO Consortium
20. Gold LS, etal., Cancer Epidemiol. 2009 Oct;33(3-4):276-80. doi: 10.1016/j.canep.2009.08.005. Epub 2009 Sep 6.
21. Holler R, etal., Biochem Biophys Res Commun. 1997 Jul 30;236(3):754-9.
22. Horska A, etal., Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:100-3.
23. Hu G, etal., Respirology. 2008 Nov;13(6):837-50.
24. Ishikawa K, etal., Jpn J Ophthalmol. 2005 Mar-Apr;49(2):121-6.
25. Jia Y, etal., Microvasc Res. 2011 Jan;81(1):73-80. Epub 2010 Nov 12.
26. KEGG
27. Kezic S, etal., Toxicol Ind Health. 2006 Aug;22(7):281-9.
28. Khrunin AV, etal., Pharmacogenomics. 2014 Feb;15(3):329-37. doi: 10.2217/pgs.13.237.
29. Kim WJ, etal., Eur Respir J. 2010 Jun 4.
30. Korytina GF, etal., Mol Biol (Mosk). 2003 Sep-Oct;37(5):784-92.
31. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
32. Lakhdar R, etal., Genet Test Mol Biomarkers. 2010 Oct 9.
33. Lebailly P, etal., Br J Haematol. 2002 Mar;116(3):587-94.
34. Li N, etal., J Mol Cell Cardiol. 2009 Dec;47(6):835-45. Epub 2009 Aug 28.
35. Lin TS, etal., Oncol Rep. 2007 Mar;17(3):565-72.
36. Lincz LF, etal., Leuk Res. 2007 Jun;31(6):759-63. Epub 2006 Sep 1.
37. Liu JY, etal., Br J Pharmacol. 2009 Jan;156(2):284-96. Epub 2009 Jan 13.
38. Liu M, etal., Eur J Neurosci. 2006 Apr;23(8):2027-34.
39. Makhlouf MM and Magdy RI, Biomarkers. 2016 Mar 21:1-8.
40. Martino A, etal., Cancer Epidemiol Biomarkers Prev. 2014 Apr;23(4):670-4. doi: 10.1158/1055-9965.EPI-13-1115. Epub 2014 Feb 12.
41. Matheson MC, etal., Hum Biol. 2006 Dec;78(6):705-17.
42. Mesange F, etal., Biochem J. 1998 Aug 15;334 ( Pt 1):107-12.
43. MGD data from the GO Consortium
44. NCBI rat LocusLink and RefSeq merged data July 26, 2002
45. Neri M, etal., Int J Hyg Environ Health. 2006 Jul;209(4):393-8. Epub 2006 May 11.
46. OMIM Disease Annotation Pipeline
47. Pipeline to import KEGG annotations from KEGG into RGD
48. Pipeline to import SMPDB annotations from SMPDB into RGD
49. Porter TD, etal., Arch Biochem Biophys 1986 Jul;248(1):121-9.
50. Qamar W, etal., Toxicology. 2012 Jan 27;291(1-3):25-31. Epub 2011 Oct 25.
51. Revermann M, etal., Arterioscler Thromb Vasc Biol. 2010 May;30(5):909-14. Epub 2010 Mar 11.
52. RGD automated data pipeline
53. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
54. RGD automated import pipeline for gene-chemical interactions
55. Salam MT, etal., Thorax. 2007 Dec;62(12):1050-7. Epub 2007 Aug 21.
56. Sarmanova J, etal., Hum Mol Genet. 2001 Jun 1;10(12):1265-73.
57. Sharma RN, etal., Cancer Res. 1981 Sep;41(9 Pt 1):3311-9.
58. Silveira Vda S, etal., Environ Mol Mutagen. 2010 Jan;51(1):48-56. doi: 10.1002/em.20510.
59. Simmons DL and Kasper CB, Arch Biochem Biophys. 1989 May 15;271(1):10-20.
60. Smith CA and Harrison DJ, Lancet. 1997 Aug 30;350(9078):630-3.
61. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
62. Takeyabu K, etal., Eur Respir J. 2000 May;15(5):891-4.
63. Taura KI, etal., Biochem Biophys Res Commun. 2000 Jul 14;273(3):1048-52.
64. Tumer TB, etal., Arch Toxicol. 2012 Mar;86(3):431-9. doi: 10.1007/s00204-011-0760-8. Epub 2011 Oct 9.
65. Youssry I, etal., J Pediatr Hematol Oncol. 2011 Mar;33(2):89-92. doi: 10.1097/MPH.0b013e3181ff78ce.
66. Zhang W, etal., J Cereb Blood Flow Metab. 2009 Aug;29(8):1475-81. Epub 2009 May 27.
67. Zhu Q, etal., J Biol Chem. 1999 Sep 24;274(39):27898-904.
68. Zhu QS, etal., Biochim Biophys Acta. 2003 Jul 30;1638(3):208-16.
69. Zusterzeel PL, etal., J Med Genet. 2001 Apr;38(4):234-7.
Additional References at PubMed
PMID:10446164   PMID:15047867   PMID:15489334   PMID:20396348   PMID:22061827   PMID:24958911   PMID:28736260  


Genomics

Comparative Map Data
Ephx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21392,714,315 - 92,744,124 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1392,714,315 - 92,790,235 (-)Ensembl
Rnor_6.01399,271,390 - 99,300,580 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,271,366 - 99,300,579 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,268,704 - 104,297,617 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,722,973 - 96,752,940 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11396,912,126 - 96,925,415 (-)NCBI
Celera1392,256,740 - 92,285,424 (-)NCBICelera
RH 3.4 Map13631.9RGD
Cytogenetic Map13q26NCBI
EPHX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1225,810,124 - 225,845,563 (+)EnsemblGRCh38hg38GRCh38
GRCh381225,810,124 - 225,845,563 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371225,997,826 - 226,033,264 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361224,079,599 - 224,099,884 (+)NCBINCBI36hg18NCBI36
Build 341222,319,710 - 222,339,996NCBI
Celera1199,188,853 - 199,224,327 (+)NCBI
Cytogenetic Map1q42.12NCBI
HuRef1196,515,661 - 196,550,964 (+)NCBIHuRef
CHM1_11227,270,121 - 227,305,585 (+)NCBICHM1_1
Ephx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,817,121 - 180,845,134 (-)NCBIGRCm39mm39
GRCm39 Ensembl1180,803,775 - 180,848,469 (-)Ensembl
GRCm381180,989,556 - 181,017,569 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,976,210 - 181,020,904 (-)EnsemblGRCm38mm10GRCm38
MGSCv371182,919,687 - 182,947,626 (-)NCBIGRCm37mm9NCBIm37
MGSCv361182,826,231 - 182,854,170 (-)NCBImm8
Celera1188,055,356 - 188,083,565 (-)NCBICelera
Cytogenetic Map1H4NCBI
cM Map184.48NCBI
Ephx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955520116,363 - 128,665 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955520116,363 - 142,983 (-)NCBIChiLan1.0ChiLan1.0
EPHX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11206,272,866 - 206,307,581 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1206,272,866 - 206,307,581 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01201,271,366 - 201,306,635 (+)NCBIMhudiblu_PPA_v0panPan3
EPHX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1738,964,319 - 39,004,902 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl738,964,338 - 38,999,238 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha738,446,530 - 38,481,524 (-)NCBI
ROS_Cfam_1.0738,798,288 - 38,833,289 (-)NCBI
ROS_Cfam_1.0 Ensembl738,798,291 - 38,833,208 (-)Ensembl
UMICH_Zoey_3.1738,638,072 - 38,673,037 (-)NCBI
UNSW_CanFamBas_1.0738,646,207 - 38,681,169 (-)NCBI
UU_Cfam_GSD_1.0738,915,983 - 38,950,983 (-)NCBI
Ephx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934452,094,468 - 52,163,372 (-)NCBI
SpeTri2.0NW_0049365262,589,254 - 2,652,831 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1013,735,170 - 13,773,071 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11013,757,489 - 13,773,071 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21016,016,584 - 16,054,476 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1253,924,396 - 3,960,264 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl253,924,606 - 3,945,535 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660553,930,701 - 3,966,856 (-)NCBIVero_WHO_p1.0
Ephx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248356,161,930 - 6,181,016 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Ephx1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,716,681 - 92,716,790 (+)MAPPERmRatBN7.2
Rnor_6.01399,273,757 - 99,273,865NCBIRnor6.0
Rnor_5.013104,271,071 - 104,271,179UniSTSRnor5.0
RGSC_v3.41396,725,337 - 96,725,445UniSTSRGSC3.4
Celera1392,259,107 - 92,259,215UniSTS
Cytogenetic Map13q26UniSTS
RH94562  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,790,387 - 92,790,474 (+)MAPPERmRatBN7.2
mRatBN7.21392,714,240 - 92,714,327 (+)MAPPERmRatBN7.2
Rnor_6.01399,271,316 - 99,271,402NCBIRnor6.0
Rnor_6.01399,346,749 - 99,346,835NCBIRnor6.0
Rnor_5.013104,268,630 - 104,268,716UniSTSRnor5.0
Rnor_5.013104,343,786 - 104,343,872UniSTSRnor5.0
RGSC_v3.41396,799,199 - 96,799,285UniSTSRGSC3.4
RGSC_v3.41396,722,896 - 96,722,982UniSTSRGSC3.4
Celera1392,256,666 - 92,256,752UniSTS
Celera1392,331,667 - 92,331,753UniSTS
RH 3.4 Map13631.9UniSTS
Cytogenetic Map13q26UniSTS
UniSTS:142997  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,716,681 - 92,716,791 (+)MAPPERmRatBN7.2
Rnor_6.01399,273,757 - 99,273,866NCBIRnor6.0
Rnor_5.013104,271,071 - 104,271,180UniSTSRnor5.0
RGSC_v3.41396,725,337 - 96,725,446UniSTSRGSC3.4
Celera1392,259,107 - 92,259,216UniSTS
Cytogenetic Map13q26UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:20
Interacting mature miRNAs:20
Transcripts:ENSRNOT00000004780
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1 1 1
Medium 3 6 52 40 15 40 2 39 35 34 11
Low 37 4 4 8 9 35 7 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004780   ⟹   ENSRNOP00000004780
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,714,319 - 92,790,235 (-)Ensembl
Rnor_6.0 Ensembl1399,271,390 - 99,287,887 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000029787   ⟹   ENSRNOP00000034917
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,714,316 - 92,744,054 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085279   ⟹   ENSRNOP00000074206
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,714,315 - 92,727,979 (-)Ensembl
Rnor_6.0 Ensembl1399,271,366 - 99,300,579 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109605   ⟹   ENSRNOP00000080132
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,714,315 - 92,725,978 (-)Ensembl
RefSeq Acc Id: NM_001034090   ⟹   NP_001029262
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,714,315 - 92,744,124 (-)NCBI
Rnor_6.01399,271,390 - 99,300,580 (-)NCBI
Rnor_5.013104,268,704 - 104,297,617 (-)NCBI
RGSC_v3.41396,722,973 - 96,752,940 (-)RGD
Celera1392,256,740 - 92,285,424 (-)NCBI
Sequence:
RefSeq Acc Id: NM_012844   ⟹   NP_036976
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,714,315 - 92,731,364 (-)NCBI
Rnor_6.01399,271,390 - 99,287,887 (-)NCBI
Rnor_5.013104,268,704 - 104,297,617 (-)NCBI
RGSC_v3.41396,722,973 - 96,752,940 (-)RGD
Celera1392,256,740 - 92,272,686 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090378   ⟹   XP_038946306
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,714,315 - 92,731,911 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001029262   ⟸   NM_001034090
- Peptide Label: precursor
- UniProtKB: P07687 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_036976   ⟸   NM_012844
- Peptide Label: precursor
- UniProtKB: P07687 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074206   ⟸   ENSRNOT00000085279
RefSeq Acc Id: ENSRNOP00000004780   ⟸   ENSRNOT00000004780
RefSeq Acc Id: XP_038946306   ⟸   XM_039090378
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000080132   ⟸   ENSRNOT00000109605
RefSeq Acc Id: ENSRNOP00000034917   ⟸   ENSRNOT00000029787
Protein Domains
EHN

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699065
Promoter ID:EPDNEW_R9590
Type:multiple initiation site
Name:Ephx1_2
Description:epoxide hydrolase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9591  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01399,287,887 - 99,287,947EPDNEW
RGD ID:13699066
Promoter ID:EPDNEW_R9591
Type:initiation region
Name:Ephx1_1
Description:epoxide hydrolase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9590  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01399,300,536 - 99,300,596EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 104279058 104279059 C T snv ZF (KyushuU), KFRS3B/Kyo (KyushuU), F344/Jcl (KyushuU), F344/Stm (KyushuU), IS-Tlk/Kyo (KyushuU), ZFDM (KyushuU), F344/DuCrlCrlj (KyushuU), NIG-III/Hok (KyushuU), IS/Kyo (KyushuU), SDLEF7/Barth (UDEL), SBH/Ygl (MCW), F344/NSlc (KyushuU)
13 104279123 104279124 T A snv ZFDM (KyushuU), ZF (KyushuU), KFRS3B/Kyo (KyushuU), F344/Jcl (KyushuU), F344/Stm (KyushuU), IS-Tlk/Kyo (KyushuU), F344/NSlc (KyushuU), F344/DuCrlCrlj (KyushuU), NIG-III/Hok (KyushuU), IS/Kyo (KyushuU), SBH/Ygl (MCW), SDLEF7/Barth (UDEL)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 92725270 92725271 C T snv F344/DuCrl (2019), F344/NCrl (2019), WAG/RijCrl (2020), PVG/Seac (2019), MWF/Hsd (2019), MR/N (2020), M520/N (2020), M520/NRrrcMcwi (2019), LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), FXLE18/Stm (2020), FXLE16/Stm (2020), F344/Stm (2019), F344/N (2020)
13 92725335 92725336 T A snv F344/DuCrl (2019), WAG/RijCrl (2020), MWF/Hsd (2019), MR/N (2020), M520/N (2020), M520/NRrrcMcwi (2019), LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), FXLE18/Stm (2020), FXLE16/Stm (2020), F344/Stm (2019), F344/N (2020), F344/NCrl (2019), PVG/Seac (2019)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 99281798 99281799 C T snv SBH/Ygl (MCW), PVG/Seac (2019), MWF/Hsd (2019), MR/N (2020), M520/N (2020), M520/NRrrcMcwi (2019), LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), FXLE18/Stm (2020), FXLE16/Stm (2020), F344/Stm (2019), F344/N (2020), F344/NCrl (2019), F344/DuCrl (2019), MR/N (MCW), M520/N (MCW), F344/NRrrc (MCW), WAG/RijCrl (2020)
13 99281863 99281864 T A snv WAG/RijCrl (2020), SBH/Ygl (MCW), MWF/Hsd (2019), MR/N (2020), M520/N (2020), M520/NRrrcMcwi (2019), LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), FXLE18/Stm (2020), FXLE16/Stm (2020), F344/Stm (2019), F344/N (2020), F344/NCrl (2019), F344/DuCrl (2019), M520/N (MCW), F344/NRrrc (MCW), PVG/Seac (2019)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 96734188 96734189 C T snv F344/NRrrc (KNAW), M520/N (KNAW), LCR/2Mco (UMich), HCR/2Mco (UMich), LCR/1Mco (UMich), HCR/1Mco (UMich), WAG/Rij (ICL), SBH/Ygl (ICL), F344/NCrl (ICL), BBDP/WorN (ICL), MR/N (KNAW)
13 96734253 96734254 T A snv HCR/2Mco (UMich), LCR/1Mco (UMich), HCR/1Mco (UMich), SBH/Ygl (ICL), F344/NHsd (ICAHN), M520/N (KNAW), F344/NRrrc (KNAW), LCR/2Mco (UMich), F344/NCrl (ICL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2557 AgrOrtholog
Ensembl Genes ENSRNOG00000003515 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000037928 UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000004780 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000034917 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000074206 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004780 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000029787 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000085279 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6889368 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Epox_hydrolase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Epoxide_hydro_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Epoxide_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25315 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72921 IMAGE-MGC_LOAD
NCBI Gene 25315 ENTREZGENE
Pfam EHN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB EPHX1 RGD
PhenoGen Ephx1 PhenoGen
PIRSF Epoxide_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS EPOXHYDRLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F1LTS8_RAT UniProtKB/TrEMBL
  HYEP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Ephx1  epoxide hydrolase 1  Ephx1  epoxide hydrolase 1, microsomal (xenobiotic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-14 Ephx1  epoxide hydrolase 1, microsomal (xenobiotic)  Ephx1  epoxide hydrolase 1, microsomal  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Ephx1  epoxide hydrolase 1, microsomal    epoxide hydrolase 1  Name updated 1299863 APPROVED
2002-11-06 Ephx1  epoxide hydrolase 1    Epoxide hydrolase 1 (microsomal xenobiotic hydrolase)  Name updated 625702 APPROVED
2002-06-10 Ephx1  Epoxide hydrolase 1 (microsomal xenobiotic hydrolase)      Symbol and Name status set to approved 70586 APPROVED