(+)-albicanol multiple interactions ISO RGD:733529 6480464 albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA], albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1605110 6480464 epigallocatechin gallate promotes the reaction [arsenite results in increased expression of KEAP1 mRNA] CTD PMID:29572906 (-)-epigallocatechin 3-gallate increases expression ISO RGD:1605110 6480464 epigallocatechin gallate results in increased expression of KEAP1 protein CTD PMID:35218280 (R)-lipoic acid increases expression ISO RGD:1605110 6480464 Thioctic Acid results in increased expression of KEAP1 protein CTD PMID:19033392 (R)-lipoic acid multiple interactions ISO RGD:733529 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of KEAP1 protein] CTD PMID:34252510 (R,R,R)-alpha-tocopherol multiple interactions ISO RGD:1605110 6480464 alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 mRNA], alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:36058301 1,2-dimethylhydrazine multiple interactions ISO RGD:733529 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KEAP1 mRNA CTD PMID:22206623 1,2-naphthoquinone affects response to substance ISO RGD:733529 6480464 KEAP1 protein affects the susceptibility to 1, 2-naphthoquinone CTD PMID:21384861 1,2-naphthoquinone increases metabolic processing ISO RGD:733529 6480464 1, 2-naphthoquinone results in increased metabolism of KEAP1 protein CTD PMID:21384861 , PMID:25807370 1-chloro-2,4-dinitrobenzene multiple interactions ISO RGD:1605110 6480464 Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein] more ... CTD PMID:19033392 , PMID:25742418 1-chloro-2,4-dinitrobenzene decreases expression ISO RGD:733529 6480464 Dinitrochlorobenzene results in decreased expression of KEAP1 mRNA CTD PMID:28219650 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:1605110 6480464 Dinitrochlorobenzene results in increased expression of KEAP1 protein CTD PMID:19033392 1-chloro-2,4-dinitrobenzene affects metabolic processing ISO RGD:733529 6480464 Dinitrochlorobenzene affects the metabolism of KEAP1 protein CTD PMID:18785192 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:733529 6480464 1 more ... CTD PMID:33368846 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO RGD:733529 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:33368846 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole decreases export ISO RGD:1605110 6480464 KEAP1 protein results in decreased export of bisbenzimide ethoxide trihydrochloride CTD PMID:25841332 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:733529 6480464 Tetrachlorodibenzodioxin affects the expression of KEAP1 mRNA CTD PMID:21570461 2,4-di-tert-butylphenol multiple interactions ISO RGD:1605110 6480464 [SAG compound co-treated with 2, 4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2] results in increased expression of KEAP1 mRNA CTD PMID:36682590 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of KEAP1 mRNA CTD PMID:21346803 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:733529 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein] more ... CTD PMID:35691465 2-tert-butylhydroquinone increases expression ISO RGD:1605110 6480464 2-tert-butylhydroquinone results in increased expression of KEAP1 protein CTD PMID:19033392 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in decreased expression of KEAP1 protein] CTD PMID:31726083 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of KEAP1 protein CTD PMID:31726083 2-tert-butylhydroquinone decreases response to substance ISO RGD:1605110 6480464 KEAP1 protein mutant form results in decreased susceptibility to 2-tert-butylhydroquinone CTD PMID:23589329 2-tert-butylhydroquinone multiple interactions ISO RGD:1605110 6480464 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein] more ... CTD PMID:18417180 , PMID:23589329 2-tert-butylhydroquinone multiple interactions ISO RGD:733529 6480464 2-tert-butylhydroquinone inhibits the reaction [2 more ... CTD PMID:18512965 more ... 2-tert-butylhydroquinone affects binding ISO RGD:733529 6480464 2-tert-butylhydroquinone binds to KEAP1 protein CTD PMID:19808700 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:1605110 6480464 3 more ... CTD PMID:24709675 3,3',4,4',5-pentachlorobiphenyl affects expression ISO RGD:733529 6480464 3 more ... CTD PMID:31563530 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:1605110 6480464 3 more ... CTD PMID:24709675 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:733529 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of KEAP1 mRNA CTD PMID:26251327 3,4-methylenedioxymethamphetamine increases methylation ISO RGD:733529 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased methylation of KEAP1 promoter CTD PMID:26251327 3,5-diethoxycarbonyl-1,4-dihydrocollidine affects response to substance ISO RGD:733529 6480464 KEAP1 gene affects the susceptibility to 3 more ... CTD PMID:30215777 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO RGD:733529 6480464 KEAP1 gene mutant form promotes the reaction [3 more ... CTD PMID:30825315 3,5-diethoxycarbonyl-1,4-dihydrocollidine decreases response to substance ISO RGD:733529 6480464 KEAP1 gene mutant form results in decreased susceptibility to 3 more ... CTD PMID:30825315 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of KEAP1 protein CTD PMID:34915118 3-methyladenine decreases expression ISO RGD:1605110 6480464 3-methyladenine results in decreased expression of KEAP1 protein CTD PMID:29781141 3-methylcholanthrene increases expression ISO RGD:733529 6480464 Methylcholanthrene results in increased expression of KEAP1 mRNA CTD PMID:23712962 3-phenylprop-2-enal affects expression ISO RGD:733529 6480464 cinnamaldehyde affects the expression of KEAP1 mRNA CTD PMID:28219650 3-phenylprop-2-enal increases expression ISO RGD:1605110 6480464 cinnamaldehyde results in increased expression of KEAP1 protein CTD PMID:19033392 4,4'-diaminodiphenylmethane decreases expression ISO RGD:733529 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of KEAP1 mRNA CTD PMID:18648102 4,4'-dipyridyl disulfide multiple interactions ISO RGD:733529 6480464 4 more ... CTD PMID:15865434 4,4'-sulfonyldiphenol increases expression ISO RGD:733529 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of KEAP1 mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of KEAP1 protein CTD PMID:36541330 4,4'-sulfonyldiphenol decreases methylation ISO RGD:1605110 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of KEAP1 gene CTD PMID:31601247 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of KEAP1 mRNA CTD PMID:21346803 5-aza-2'-deoxycytidine increases expression ISO RGD:1605110 6480464 Decitabine results in increased expression of KEAP1 mRNA CTD PMID:20124447 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1605110 6480464 [Decitabine affects the methylation of KEAP1 promoter] which affects the expression of KEAP1 mRNA more ... CTD PMID:18555005 , PMID:26409248 5-fluorouracil affects response to substance ISO RGD:1605110 6480464 KEAP1 protein affects the susceptibility to Fluorouracil CTD PMID:18692501 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:24995432 , PMID:33759307 7,12-dimethyltetraphene multiple interactions EXP 6480464 betulin inhibits the reaction [9 more ... CTD PMID:24995432 , PMID:33759307 7,8-dihydroxycoumarin decreases expression ISO RGD:1605110 6480464 daphnetin results in decreased expression of KEAP1 protein CTD PMID:30738023 [6]-Shogaol decreases expression ISO RGD:1605110 6480464 shogaol metabolite results in decreased expression of KEAP1 protein, shogaol results in decreased expression of KEAP1 protein CTD PMID:25148906 [6]-Shogaol multiple interactions ISO RGD:733529 6480464 KEAP1 protein affects the reaction [shogaol analog results in increased expression of HMOX1 protein] more ... CTD PMID:23899529 [6]-Shogaol increases alkylation ISO RGD:1605110 6480464 shogaol results in increased alkylation of KEAP1 protein CTD PMID:25148906 acrolein multiple interactions ISO RGD:1605110 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein, Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein] CTD PMID:19608619 acrolein increases expression ISO RGD:733529 6480464 Acrolein results in increased expression of KEAP1 protein CTD PMID:30608172 acrolein multiple interactions ISO RGD:733529 6480464 [Ovalbumin co-treated with Acrolein] results in increased expression of KEAP1 protein CTD PMID:30608172 acrylamide affects expression EXP 6480464 Acrylamide affects the expression of KEAP1 protein CTD PMID:29426002 acrylamide increases expression ISO RGD:733529 6480464 Acrylamide results in increased expression of KEAP1 mRNA CTD PMID:34896238 acrylamide multiple interactions ISO RGD:733529 6480464 [NLRP3 gene mutant form affects the susceptibility to Acrylamide] which results in increased expression of KEAP1 protein, Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA] CTD PMID:32014472 , PMID:34896238 aflatoxin B1 multiple interactions ISO RGD:733529 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 mRNA], Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 protein] CTD PMID:35063475 aflatoxin B1 multiple interactions EXP 6480464 [Aflatoxin B1 co-treated with caryophyllene] results in increased expression of KEAP1 protein CTD PMID:34506763 aflatoxin B1 decreases expression ISO RGD:733529 6480464 Aflatoxin B1 results in decreased expression of KEAP1 mRNA, Aflatoxin B1 results in decreased expression of KEAP1 protein CTD PMID:35063475 aldehydo-D-glucose multiple interactions ISO RGD:733529 6480464 [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 aldehydo-D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:35191607 all-trans-retinoic acid multiple interactions ISO RGD:1605110 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of KEAP1 mRNA CTD PMID:15894607 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of KEAP1 protein CTD PMID:30267739 alpha,alpha-trehalose multiple interactions EXP 6480464 Trehalose inhibits the reaction [cadmium acetate results in decreased expression of KEAP1 protein] CTD PMID:29140578 alpha-D-galactose multiple interactions ISO RGD:733529 6480464 albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA], albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 alpha-D-galactose increases expression ISO RGD:733529 6480464 Galactose results in increased expression of KEAP1 mRNA, Galactose results in increased expression of KEAP1 protein CTD PMID:33761044 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of KEAP1 mRNA CTD PMID:17991464 amitraz multiple interactions EXP 6480464 KEAP1 protein affects the reaction [amitraz results in decreased expression of CAT protein] more ... CTD PMID:31029719 amitraz increases expression EXP 6480464 amitraz results in increased expression of KEAP1 protein CTD PMID:31029719 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of KEAP1 mRNA CTD PMID:16483693 andrographolide decreases expression ISO RGD:1605110 6480464 andrographolide results in decreased expression of KEAP1 mRNA, andrographolide results in decreased expression of KEAP1 protein CTD PMID:29355602 , PMID:35724838 anethole multiple interactions EXP 6480464 anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA], anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein] CTD PMID:35430261 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1605110 6480464 pyrazolanthrone inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 aristolochic acid A multiple interactions ISO RGD:733529 6480464 bardoxolone methyl inhibits the reaction [aristolochic acid I results in increased expression of KEAP1 protein] CTD PMID:24530882 aristolochic acid A decreases expression EXP 6480464 aristolochic acid I results in decreased expression of KEAP1 mRNA, aristolochic acid I results in decreased expression of KEAP1 protein CTD PMID:36037877 aristolochic acid A multiple interactions EXP 6480464 Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 mRNA], Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 protein] CTD PMID:36037877 aristolochic acid A increases expression ISO RGD:1605110 6480464 aristolochic acid I results in increased expression of KEAP1 mRNA CTD PMID:33212167 aristolochic acid A increases expression ISO RGD:733529 6480464 aristolochic acid I results in increased expression of KEAP1 protein CTD PMID:24530882 arotinoid acid multiple interactions ISO RGD:1605110 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane affects response to substance ISO RGD:733529 6480464 KEAP1 protein affects the susceptibility to Arsenic CTD PMID:19808700 arsane increases methylation ISO RGD:1605110 6480464 Arsenic results in increased methylation of KEAP1 promoter CTD PMID:29247444 arsane affects binding ISO RGD:733529 6480464 Arsenic binds to KEAP1 protein CTD PMID:19808700 arsane increases expression ISO RGD:1605110 6480464 Arsenic results in increased expression of KEAP1 mRNA, Arsenic results in increased expression of KEAP1 protein CTD PMID:14567983 arsenic atom increases expression ISO RGD:1605110 6480464 Arsenic results in increased expression of KEAP1 mRNA, Arsenic results in increased expression of KEAP1 protein CTD PMID:14567983 arsenic atom increases methylation ISO RGD:1605110 6480464 Arsenic results in increased methylation of KEAP1 promoter CTD PMID:29247444 arsenic atom affects response to substance ISO RGD:733529 6480464 KEAP1 protein affects the susceptibility to Arsenic CTD PMID:19808700 arsenic atom affects binding ISO RGD:733529 6480464 Arsenic binds to KEAP1 protein CTD PMID:19808700 arsenite(3-) decreases expression ISO RGD:1605110 6480464 arsenite results in decreased expression of KEAP1 mRNA, arsenite results in decreased expression of KEAP1 protein CTD PMID:22476201 arsenite(3-) affects response to substance ISO RGD:1605110 6480464 KEAP1 protein affects the susceptibility to arsenite CTD PMID:22476201 arsenite(3-) multiple interactions ISO RGD:1605110 6480464 epigallocatechin gallate promotes the reaction [arsenite results in increased expression of KEAP1 mRNA] more ... CTD PMID:22476201 , PMID:29572906 arsenite(3-) increases expression ISO RGD:1605110 6480464 arsenite results in increased expression of KEAP1 mRNA, arsenite results in increased expression of KEAP1 protein CTD PMID:22476201 , PMID:29572906 arsenous acid decreases response to substance ISO RGD:1605110 6480464 KEAP1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:22684020 arsenous acid multiple interactions EXP 6480464 crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 arsenous acid increases expression ISO RGD:1605110 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA, Arsenic Trioxide results in increased expression of KEAP1 protein CTD PMID:15894607 more ... arsenous acid affects response to substance ISO RGD:1605110 6480464 KEAP1 gene mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:30815697 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of KEAP1 protein CTD PMID:24634002 , PMID:32920515 arsenous acid increases response to substance ISO RGD:1605110 6480464 KEAP1 mRNA results in increased susceptibility to Arsenic Trioxide CTD PMID:26708503 arsenous acid multiple interactions ISO RGD:1605110 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of KEAP1 mRNA more ... CTD PMID:15894607 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA CTD PMID:29223816 atrazine decreases expression ISO RGD:1605110 6480464 Atrazine results in decreased expression of KEAP1 mRNA CTD PMID:22378314 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of KEAP1 mRNA, Atrazine results in decreased expression of KEAP1 protein CTD PMID:34624533 atrazine decreases expression ISO RGD:733529 6480464 Atrazine results in decreased expression of KEAP1 mRNA, Atrazine results in decreased expression of KEAP1 protein CTD PMID:30360616 more ... atrazine multiple interactions ISO RGD:733529 6480464 Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA], Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein] CTD PMID:30360616 , PMID:36216167 aureusidin decreases expression EXP 6480464 aureusidin results in decreased expression of KEAP1 mRNA, aureusidin results in decreased expression of KEAP1 protein CTD PMID:31790703 azathioprine affects response to substance ISO RGD:733529 6480464 KEAP1 protein affects the susceptibility to Azathioprine CTD PMID:21803983 bafilomycin A1 multiple interactions ISO RGD:1605110 6480464 bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 Bardoxolone methyl increases expression ISO RGD:1605110 6480464 bardoxolone methyl results in increased expression of KEAP1 protein CTD PMID:27358234 Bardoxolone methyl decreases expression ISO RGD:1605110 6480464 bardoxolone methyl results in decreased expression of KEAP1 mRNA CTD PMID:35724838 Bardoxolone methyl multiple interactions ISO RGD:733529 6480464 bardoxolone methyl inhibits the reaction [aristolochic acid I results in increased expression of KEAP1 protein] CTD PMID:24530882 belinostat decreases expression ISO RGD:1605110 6480464 belinostat results in decreased expression of KEAP1 mRNA CTD PMID:19606018 benzene decreases expression ISO RGD:1605110 6480464 Benzene results in decreased expression of KEAP1 mRNA CTD PMID:33064461 benzene increases expression ISO RGD:733529 6480464 Benzene results in increased expression of KEAP1 protein CTD PMID:36306860 benzene-1,2,4-triol increases expression ISO RGD:1605110 6480464 hydroxyhydroquinone results in increased expression of KEAP1 mRNA CTD PMID:17572062 benzo[a]pyrene increases expression ISO RGD:733529 6480464 Benzo(a)pyrene results in increased expression of KEAP1 mRNA CTD PMID:21569818 , PMID:22228805 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of KEAP1 protein CTD PMID:36736873 benzo[a]pyrene increases expression ISO RGD:1605110 6480464 Benzo(a)pyrene results in increased expression of KEAP1 mRNA CTD PMID:20106945 more ... benzo[a]pyrene decreases expression ISO RGD:1605110 6480464 Benzo(a)pyrene results in decreased expression of KEAP1 mRNA, Benzo(a)pyrene results in decreased expression of KEAP1 protein CTD PMID:20498004 , PMID:25946486 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1605110 6480464 7 more ... CTD PMID:19150397 benzoquinones multiple interactions ISO RGD:733529 6480464 Benzoquinones analog binds to and results in increased metabolism of KEAP1 protein CTD PMID:21651925 betulin multiple interactions EXP 6480464 betulin inhibits the reaction [9 more ... CTD PMID:33759307 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:733529 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA], Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 protein] CTD PMID:35917956 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:733529 6480464 Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA, Diethylhexyl Phthalate results in decreased expression of KEAP1 protein CTD PMID:35917956 bisdemethoxycurcumin multiple interactions ISO RGD:733529 6480464 KEAP1 protein inhibits the reaction [bisdemethoxycurcumin results in increased expression of HMOX1 mRNA] CTD PMID:17535857 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of KEAP1 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:733529 6480464 bisphenol A results in increased expression of KEAP1 mRNA CTD PMID:32156529 bisphenol A decreases expression EXP 6480464 bisphenol A analog results in decreased expression of KEAP1 mRNA, bisphenol A analog results in decreased expression of KEAP1 protein CTD PMID:35427877 bisphenol A multiple interactions ISO RGD:1605110 6480464 [[ginger extract results in increased abundance of Oils, Volatile] which co-treated with bisphenol A] affects the expression of KEAP1 protein CTD PMID:33376534 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of KEAP1 gene CTD PMID:28505145 bleomycin A2 multiple interactions EXP 6480464 celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein] CTD PMID:26768587 bleomycin A2 decreases expression EXP 6480464 Bleomycin results in decreased expression of KEAP1 protein CTD PMID:26768587 bromosulfophthalein decreases glutathionylation ISO RGD:733529 6480464 KEAP1 protein results in decreased glutathionylation of Sulfobromophthalein CTD PMID:19246623 bromosulfophthalein decreases transport ISO RGD:733529 6480464 KEAP1 protein results in decreased transport of Sulfobromophthalein CTD PMID:19246623 Brusatol multiple interactions ISO RGD:1605110 6480464 [KEAP1 protein results in decreased expression of NFE2L2 protein] which results in decreased susceptibility to brusatol more ... CTD PMID:21205897 , PMID:32682831 Brusatol multiple interactions EXP 6480464 brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KEAP1 protein] CTD PMID:34695510 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of KEAP1 mRNA CTD PMID:19167457 cadmium atom increases degradation EXP 6480464 Cadmium results in increased degradation of KEAP1 protein CTD PMID:27658547 cadmium atom increases expression ISO RGD:733529 6480464 Cadmium results in increased expression of KEAP1 mRNA CTD PMID:37270049 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KEAP1 mRNA more ... CTD PMID:34695510 , PMID:36718047 cadmium dichloride decreases expression ISO RGD:733529 6480464 Cadmium Chloride results in decreased expression of KEAP1 mRNA CTD PMID:20061341 cadmium dichloride decreases expression ISO RGD:1605110 6480464 Cadmium Chloride results in decreased expression of KEAP1 protein CTD PMID:35122928 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of KEAP1 protein CTD PMID:35122928 cadmium dichloride affects folding ISO RGD:733529 6480464 Cadmium Chloride affects the folding of KEAP1 protein CTD PMID:30261176 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KEAP1 mRNA more ... CTD PMID:34695510 , PMID:36718047 cadmium dichloride affects binding ISO RGD:733529 6480464 Cadmium Chloride binds to KEAP1 protein CTD PMID:19808700 , PMID:26827822 cadmium dichloride multiple interactions ISO RGD:733529 6480464 [Cadmium Chloride affects the reaction [NFE2L2 protein binds to KEAP1 protein]] affects the localization of [NFE2L2 protein binds to KEAP1 protein] more ... CTD PMID:18512965 more ... carbon disulfide decreases expression EXP 6480464 Carbon Disulfide results in decreased expression of KEAP1 protein CTD PMID:27530093 carbon monoxide multiple interactions ISO RGD:733529 6480464 Carbon Monoxide inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18845810 CCCP multiple interactions ISO RGD:1605110 6480464 [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein more ... CTD PMID:30715550 celastrol multiple interactions EXP 6480464 celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein] CTD PMID:26768587 CGP 52608 multiple interactions ISO RGD:1605110 6480464 CGP 52608 promotes the reaction [RORA protein binds to KEAP1 gene] CTD PMID:28238834 chalcones decreases expression EXP 6480464 Chalcones analog results in decreased expression of KEAP1 protein CTD PMID:23963778 CHIR 99021 multiple interactions ISO RGD:1605110 6480464 [4-(2-(5 more ... CTD PMID:34480604 chlorambucil multiple interactions ISO RGD:1605110 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil, Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil] CTD PMID:19608619 chloroacetaldehyde increases expression ISO RGD:1605110 6480464 chloroacetaldehyde results in increased expression of KEAP1 mRNA CTD PMID:25596134 choline multiple interactions ISO RGD:733529 6480464 KEAP1 affects the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of CD36 mRNA] more ... CTD PMID:20350562 cidofovir anhydrous increases expression ISO RGD:1605110 6480464 Cidofovir results in increased expression of KEAP1 mRNA CTD PMID:25596134 cisplatin multiple interactions ISO RGD:1605110 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of KEAP1 mRNA, [KEAP1 protein results in decreased stability of NFE2L2 protein] which results in increased susceptibility to Cisplatin CTD PMID:20530669 , PMID:27392435 cisplatin affects expression EXP 6480464 Cisplatin affects the expression of KEAP1 protein CTD PMID:30125553 cisplatin increases expression ISO RGD:1605110 6480464 Cisplatin results in increased expression of KEAP1 mRNA CTD PMID:25596134 , PMID:27594783 cisplatin increases response to substance ISO RGD:1605110 6480464 KEAP1 protein results in increased susceptibility to Cisplatin CTD PMID:25841332 Clivoline increases expression ISO RGD:1605110 6480464 clivorine results in increased expression of KEAP1 mRNA CTD PMID:25881548 clodronic acid increases expression ISO RGD:1605110 6480464 Clodronic Acid results in increased expression of KEAP1 mRNA CTD PMID:25596134 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KEAP1 mRNA CTD PMID:17602206 cobalt atom multiple interactions ISO RGD:733529 6480464 Zinc inhibits the reaction [Cobalt binds to KEAP1 protein] CTD PMID:15865434 cobalt atom affects binding ISO RGD:733529 6480464 Cobalt binds to KEAP1 protein CTD PMID:15865434 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of KEAP1 mRNA CTD PMID:24386269 cobalt dichloride affects response to substance ISO RGD:1605110 6480464 KEAP1 protein affects the susceptibility to cobaltous chloride CTD PMID:29966676 cobalt dichloride multiple interactions ISO RGD:1605110 6480464 KEAP1 protein inhibits the reaction [cobaltous chloride results in increased expression of GCLC mRNA] more ... CTD PMID:29966676 colistin increases expression ISO RGD:733529 6480464 Colistin results in increased expression of KEAP1 mRNA, Colistin results in increased expression of KEAP1 protein CTD PMID:34560125 copper atom multiple interactions ISO RGD:1605110 6480464 [Chelating Agents binds to Copper] which affects the expression of KEAP1 mRNA, [Chelating Agents binds to Copper] which results in increased expression of KEAP1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:1605110 6480464 [Chelating Agents binds to Copper] which affects the expression of KEAP1 mRNA, [Chelating Agents binds to Copper] which results in increased expression of KEAP1 mRNA CTD PMID:30911355 cortisol multiple interactions ISO RGD:1605110 6480464 [4-(2-(5 more ... CTD PMID:34480604 crocin-1 multiple interactions EXP 6480464 crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 CU-O LINKAGE decreases expression ISO RGD:1605110 6480464 cupric oxide results in decreased expression of KEAP1 mRNA CTD PMID:32285662 cumene hydroperoxide multiple interactions ISO RGD:1605110 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide, Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide] CTD PMID:19608619 curcumin multiple interactions ISO RGD:733529 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 mRNA] more ... CTD PMID:17535857 , PMID:35063475 curcumin decreases expression EXP 6480464 Curcumin analog results in decreased expression of KEAP1 protein, Curcumin results in decreased expression of KEAP1 protein CTD PMID:30946834 curcumin multiple interactions EXP 6480464 Curcumin analog promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein] more ... CTD PMID:30946834 , PMID:36037877 curcumin multiple interactions ISO RGD:1605110 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 mRNA] CTD PMID:31521693 curcumin increases expression ISO RGD:1605110 6480464 Curcumin results in increased expression of KEAP1 mRNA CTD PMID:23710286 curcumin decreases expression ISO RGD:733529 6480464 Curcumin analog results in decreased expression of KEAP1 protein CTD PMID:26991801 curcumin decreases expression ISO RGD:1605110 6480464 Curcumin results in decreased expression of KEAP1 mRNA CTD PMID:31521693 cyclosporin A increases expression ISO RGD:1605110 6480464 Cyclosporine results in increased expression of KEAP1 mRNA CTD PMID:25596134 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of KEAP1 mRNA CTD PMID:25596134 D-glucose multiple interactions ISO RGD:733529 6480464 [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:35191607 decabromodiphenyl ether increases expression ISO RGD:1605110 6480464 decabromobiphenyl ether results in increased expression of KEAP1 mRNA, decabromobiphenyl ether results in increased expression of KEAP1 protein CTD PMID:34571075 , PMID:35266255 decabromodiphenyl ether decreases expression ISO RGD:1605110 6480464 decabromobiphenyl ether results in decreased expression of KEAP1 protein CTD PMID:33675858 decabromodiphenyl ether multiple interactions ISO RGD:1605110 6480464 Luteolin inhibits the reaction [decabromobiphenyl ether results in decreased expression of KEAP1 protein] CTD PMID:33675858 deguelin increases expression ISO RGD:1605110 6480464 deguelin results in increased expression of KEAP1 mRNA CTD PMID:33512557 demethoxycurcumin multiple interactions ISO RGD:733529 6480464 KEAP1 protein inhibits the reaction [demethoxycurcumin results in increased expression of HMOX1 mRNA] CTD PMID:17535857 Dendrobine multiple interactions ISO RGD:1605110 6480464 dendrobine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 mRNA] more ... CTD PMID:36058301 deoxynivalenol decreases expression ISO RGD:733529 6480464 deoxynivalenol results in decreased expression of KEAP1 mRNA CTD PMID:34400200 diallyl disulfide decreases expression ISO RGD:733529 6480464 diallyl disulfide results in decreased expression of KEAP1 protein CTD PMID:34896185 diallyl disulfide multiple interactions ISO RGD:733529 6480464 diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of KEAP1 protein] CTD PMID:34896185 diallyl trisulfide decreases expression EXP 6480464 diallyl trisulfide results in decreased expression of KEAP1 protein CTD PMID:23453443 diallyl trisulfide multiple interactions ISO RGD:1605110 6480464 diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein] CTD PMID:24489685 diallyl trisulfide affects binding ISO RGD:1605110 6480464 diallyl trisulfide binds to KEAP1 protein CTD PMID:24489685 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA CTD PMID:29223816 diarsenic trioxide multiple interactions EXP 6480464 crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 diarsenic trioxide increases expression ISO RGD:1605110 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA, Arsenic Trioxide results in increased expression of KEAP1 protein CTD PMID:15894607 more ... diarsenic trioxide increases response to substance ISO RGD:1605110 6480464 KEAP1 mRNA results in increased susceptibility to Arsenic Trioxide CTD PMID:26708503 diarsenic trioxide multiple interactions ISO RGD:1605110 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of KEAP1 mRNA more ... CTD PMID:15894607 more ... diarsenic trioxide affects response to substance ISO RGD:1605110 6480464 KEAP1 gene mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:30815697 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of KEAP1 protein CTD PMID:24634002 , PMID:32920515 diarsenic trioxide decreases response to substance ISO RGD:1605110 6480464 KEAP1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:22684020 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of KEAP1 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO RGD:733529 6480464 Dibutyl Phthalate results in decreased expression of KEAP1 mRNA CTD PMID:17361019 dichloroacetyl chloride increases expression ISO RGD:733529 6480464 2 more ... CTD PMID:32073640 dichloroacetyl chloride multiple interactions ISO RGD:733529 6480464 2-tert-butylhydroquinone inhibits the reaction [2 more ... CTD PMID:32073640 diethyl maleate increases expression ISO RGD:1605110 6480464 diethyl maleate results in increased expression of KEAP1 mRNA, diethyl maleate results in increased expression of KEAP1 protein CTD PMID:27358234 more ... diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of KEAP1 mRNA CTD PMID:37077353 dihydroartemisinin affects binding ISO RGD:1605110 6480464 artenimol analog binds to KEAP1 protein CTD PMID:26340163 dimercaprol affects binding ISO RGD:733529 6480464 Dimercaprol binds to KEAP1 protein CTD PMID:19808700 dioscin multiple interactions EXP 6480464 dioscin inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:28082111 diosmetin multiple interactions EXP 6480464 diosmetin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of KEAP1 protein] more ... CTD PMID:35191607 dioxygen decreases expression ISO RGD:1605110 6480464 Oxygen deficiency results in decreased expression of KEAP1 mRNA, Oxygen deficiency results in decreased expression of KEAP1 protein CTD PMID:25596134 , PMID:34023435 dioxygen multiple interactions ISO RGD:1605110 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [KEAP1 protein results in increased degradation of NFE2L2 protein], [Ozone co-treated with Oxygen] results in increased expression of KEAP1 protein CTD PMID:26270818 , PMID:29864481 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:29139225 , PMID:35191607 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of KEAP1 protein CTD PMID:29139225 diquat multiple interactions ISO RGD:733529 6480464 [KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]] which results in increased expression of GCLC mRNA more ... CTD PMID:22762311 diquat decreases expression ISO RGD:733529 6480464 Diquat results in decreased expression of KEAP1 protein CTD PMID:36851058 disodium selenite multiple interactions EXP 6480464 Sodium Selenite inhibits the reaction [Sodium Fluoride results in decreased expression of KEAP1 mRNA] CTD PMID:36736877 divanadium pentaoxide decreases expression ISO RGD:1605110 6480464 vanadium pentoxide results in decreased expression of KEAP1 mRNA CTD PMID:17459161 dorsomorphin multiple interactions ISO RGD:1605110 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases response to substance ISO RGD:1605110 6480464 KEAP1 protein results in decreased susceptibility to Doxorubicin CTD PMID:22684020 doxorubicin increases expression ISO RGD:1605110 6480464 Doxorubicin results in increased expression of KEAP1 mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:733529 6480464 Doxorubicin results in increased expression of KEAP1 protein CTD PMID:29775573 , PMID:36811345 doxorubicin multiple interactions ISO RGD:733529 6480464 indole-3-carbinol inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein], naringin inhibits the reaction [Doxorubicin results in decreased expression of KEAP1 protein] CTD PMID:29775573 , PMID:36811345 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of KEAP1 protein CTD PMID:28082111 , PMID:37030624 doxorubicin multiple interactions EXP 6480464 dioscin inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein], SIRT1 protein affects the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:28082111 , PMID:37030624 doxorubicin increases response to substance ISO RGD:1605110 6480464 KEAP1 mRNA results in increased susceptibility to Doxorubicin CTD PMID:26708503 doxorubicin multiple interactions ISO RGD:1605110 6480464 KEAP1 protein results in decreased export of and results in increased susceptibility to Doxorubicin CTD PMID:25841332 doxorubicin affects response to substance EXP 6480464 KEAP1 protein affects the susceptibility to Doxorubicin CTD PMID:24211725 doxorubicin increases degradation EXP 6480464 Doxorubicin results in increased degradation of KEAP1 protein CTD PMID:24211725 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of KEAP1 protein CTD PMID:24211725 elemental selenium increases expression ISO RGD:1605110 6480464 Selenium results in increased expression of KEAP1 mRNA CTD PMID:19244175 ethanol multiple interactions ISO RGD:733529 6480464 [dihydromyricetin co-treated with Ethanol] results in decreased expression of KEAP1 protein CTD PMID:28419832 ethanol affects splicing ISO RGD:733529 6480464 Ethanol affects the splicing of KEAP1 mRNA CTD PMID:30319688 ethionamide multiple interactions ISO RGD:1605110 6480464 KEAP1 mRNA inhibits the reaction [Ethionamide results in increased susceptibility to arsenic trioxide] CTD PMID:26708503 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:733529 6480464 Egtazic Acid promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein] CTD PMID:15865434 ethylenediaminetetraacetic acid multiple interactions ISO RGD:733529 6480464 Edetic Acid promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein] CTD PMID:15865434 etoposide decreases response to substance ISO RGD:1605110 6480464 KEAP1 protein results in decreased susceptibility to Etoposide CTD PMID:22684020 etoposide multiple interactions ISO RGD:1605110 6480464 KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein] CTD PMID:27982581 etoposide increases response to substance ISO RGD:1605110 6480464 KEAP1 mRNA results in increased susceptibility to Etoposide CTD PMID:26708503 falcarindiol decreases activity EXP 6480464 falcarindiol results in decreased activity of KEAP1 protein CTD PMID:20026152 falcarindiol affects folding EXP 6480464 falcarindiol affects the folding of KEAP1 protein CTD PMID:20026152 falcarindiol multiple interactions EXP 6480464 falcarindiol binds to and results in increased alkylation of KEAP1 protein more ... CTD PMID:20026152 farrerol decreases expression ISO RGD:733529 6480464 farrerol results in decreased expression of KEAP1 protein CTD PMID:26111761 finasteride increases expression EXP 6480464 Finasteride results in increased expression of KEAP1 mRNA CTD PMID:24136188 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of KEAP1 mRNA CTD PMID:18035473 flutamide increases expression EXP 6480464 Flutamide results in increased expression of KEAP1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:733529 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KEAP1 mRNA CTD PMID:22206623 fumonisin B1 decreases expression ISO RGD:1605110 6480464 fumonisin B1 results in decreased expression of KEAP1 mRNA, fumonisin B1 results in decreased expression of KEAP1 protein CTD PMID:33496827 fumonisin B1 decreases expression ISO RGD:733529 6480464 fumonisin B1 results in decreased expression of KEAP1 mRNA CTD PMID:35697133 fumonisin B1 multiple interactions ISO RGD:1605110 6480464 [fumonisin B1 results in increased methylation of KEAP1 promoter] which results in decreased expression of KEAP1 mRNA CTD PMID:33496827 fumonisin B1 increases methylation ISO RGD:1605110 6480464 fumonisin B1 results in increased methylation of KEAP1 promoter CTD PMID:33496827 galactose multiple interactions ISO RGD:733529 6480464 albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA], albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 galactose increases expression ISO RGD:733529 6480464 Galactose results in increased expression of KEAP1 mRNA, Galactose results in increased expression of KEAP1 protein CTD PMID:33761044 gefitinib increases expression ISO RGD:1605110 6480464 gefitinib results in increased expression of KEAP1 mRNA CTD PMID:27639429 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of KEAP1 mRNA CTD PMID:33387578 ginsenoside Rg1 multiple interactions ISO RGD:733529 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] CTD PMID:29964319 gliclazide multiple interactions EXP 6480464 Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA], Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein] CTD PMID:21439372 glucose multiple interactions ISO RGD:733529 6480464 [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:35191607 glutathione multiple interactions ISO RGD:1605110 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in increased abundance of Glutathione more ... CTD PMID:19608619 , PMID:21972102 glutathione increases abundance ISO RGD:733529 6480464 KEAP1 gene mutant form results in increased abundance of Glutathione CTD PMID:26827822 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [falcarindiol binds to and results in increased alkylation of KEAP1 protein] CTD PMID:20026152 glutathione multiple interactions ISO RGD:733529 6480464 [KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]] which results in increased expression of GCLC mRNA more ... CTD PMID:20800667 more ... glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 glyphosate increases expression ISO RGD:1605110 6480464 glyphosate results in increased expression of KEAP1 mRNA CTD PMID:36625791 hemin decreases expression ISO RGD:733529 6480464 Hemin results in decreased expression of KEAP1 protein CTD PMID:27777014 hexaflumuron decreases expression EXP 6480464 hexafluoron results in decreased expression of KEAP1 mRNA CTD PMID:34993831 homocysteine increases expression ISO RGD:1605110 6480464 Homocysteine results in increased expression of KEAP1 protein CTD PMID:22964297 hydrogen peroxide increases expression ISO RGD:1605110 6480464 Hydrogen Peroxide results in increased expression of KEAP1 mRNA, Hydrogen Peroxide results in increased expression of KEAP1 protein CTD PMID:31705858 , PMID:36058301 hydrogen peroxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] more ... CTD PMID:30104959 , PMID:32275923 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of KEAP1 protein CTD PMID:32275923 hydrogen peroxide multiple interactions ISO RGD:1605110 6480464 4-((alpha-L-rhamnosyloxy)benzyl)isothiocyanate inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 mRNA] more ... CTD PMID:25742418 more ... hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of KEAP1 protein CTD PMID:30104959 hydrogen peroxide decreases expression ISO RGD:1605110 6480464 Hydrogen Peroxide results in decreased expression of KEAP1 mRNA, Hydrogen Peroxide results in decreased expression of KEAP1 protein CTD PMID:23410634 more ... hydrogen peroxide multiple interactions ISO RGD:733529 6480464 Hydrogen Peroxide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]] CTD PMID:15865434 hydrogen sulfide multiple interactions EXP 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat promotes the reaction [KEAP1 protein binds to NFE2L2 protein]], [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in increased expression of KEAP1 protein] CTD PMID:32064027 hydroquinone decreases expression ISO RGD:733529 6480464 hydroquinone results in decreased expression of KEAP1 protein CTD PMID:23290930 hypochlorous acid increases expression ISO RGD:733529 6480464 Hypochlorous Acid results in increased expression of KEAP1 mRNA CTD PMID:17980396 ifosfamide increases expression ISO RGD:1605110 6480464 Ifosfamide results in increased expression of KEAP1 mRNA CTD PMID:25596134 imidacloprid decreases expression EXP 6480464 imidacloprid results in decreased expression of KEAP1 mRNA CTD PMID:34993831 indole-3-methanol multiple interactions ISO RGD:733529 6480464 indole-3-carbinol inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:29775573 indometacin multiple interactions ISO RGD:1605110 6480464 Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] more ... CTD PMID:11909699 iron(III) citrate multiple interactions ISO RGD:1605110 6480464 [trigonelline co-treated with ferric citrate] results in decreased expression of KEAP1 mRNA CTD PMID:29959986 isoniazide decreases expression ISO RGD:733529 6480464 Isoniazid results in decreased expression of KEAP1 mRNA CTD PMID:33771660 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of KEAP1 mRNA CTD PMID:30303030 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of KEAP1 mRNA, Isoproterenol results in increased expression of KEAP1 protein CTD PMID:35430261 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA more ... CTD PMID:30303030 , PMID:35430261 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of KEAP1 mRNA CTD PMID:37077353 L-ascorbic acid multiple interactions ISO RGD:1605110 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA more ... CTD PMID:28285367 more ... L-ascorbic acid decreases expression ISO RGD:1605110 6480464 Ascorbic Acid results in decreased expression of KEAP1 protein CTD PMID:31610155 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:1605110 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KEAP1 mRNA CTD PMID:34480604 L-methionine multiple interactions ISO RGD:733529 6480464 KEAP1 affects the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of CD36 mRNA] more ... CTD PMID:20350562 lansoprazole increases oxidation EXP 6480464 Lansoprazole results in increased oxidation of KEAP1 protein CTD PMID:19628634 lead diacetate multiple interactions ISO RGD:1605110 6480464 [lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein more ... CTD PMID:31610155 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of KEAP1 mRNA CTD PMID:33862172 lead(0) multiple interactions ISO RGD:1605110 6480464 [lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein more ... CTD PMID:31610155 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of KEAP1 mRNA CTD PMID:24136188 linsidomine affects response to substance ISO RGD:1605110 6480464 KEAP1 mRNA affects the susceptibility to linsidomine CTD PMID:16092930 lipoic acid increases expression ISO RGD:1605110 6480464 Thioctic Acid results in increased expression of KEAP1 protein CTD PMID:19033392 lipoic acid multiple interactions ISO RGD:733529 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of KEAP1 protein] CTD PMID:34252510 lipopolysaccharide multiple interactions ISO RGD:733529 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein] more ... CTD PMID:35691465 luteolin multiple interactions ISO RGD:1605110 6480464 Luteolin inhibits the reaction [decabromobiphenyl ether results in decreased expression of KEAP1 protein] CTD PMID:33675858 lycopene multiple interactions ISO RGD:733529 6480464 Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA] more ... CTD PMID:30360616 more ... lycopene increases expression ISO RGD:733529 6480464 Lycopene results in increased expression of KEAP1 mRNA CTD PMID:36216167 manganese(II) chloride affects expression ISO RGD:733529 6480464 manganese chloride affects the expression of KEAP1 protein CTD PMID:25288107 manganese(II) chloride multiple interactions ISO RGD:733529 6480464 Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein] CTD PMID:25288107 melatonin multiple interactions ISO RGD:733529 6480464 Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein] CTD PMID:25288107 melatonin decreases expression ISO RGD:733529 6480464 Melatonin results in decreased expression of KEAP1 protein CTD PMID:25288107 menadione multiple interactions ISO RGD:1605110 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Vitamin K 3 CTD PMID:19608619 menadione decreases expression ISO RGD:1605110 6480464 Vitamin K 3 results in decreased expression of KEAP1 mRNA CTD PMID:23410634 mercury dibromide increases expression ISO RGD:1605110 6480464 mercuric bromide results in increased expression of KEAP1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1605110 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KEAP1 mRNA CTD PMID:27188386 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA], Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:33639173 metformin decreases expression EXP 6480464 Metformin results in decreased expression of KEAP1 mRNA CTD PMID:25596134 microcystin-LR affects binding ISO RGD:1605110 6480464 cyanoginosin LR binds to KEAP1 protein CTD PMID:20722399 monascin multiple interactions ISO RGD:1605110 6480464 monascin inhibits the reaction [S100B protein results in increased expression of KEAP1 protein] CTD PMID:23331247 N'-(2,4-dimethylphenyl)-N-methylformamidine increases expression EXP 6480464 U 40481 results in increased expression of KEAP1 protein CTD PMID:31029719 N'-(2,4-dimethylphenyl)-N-methylformamidine multiple interactions EXP 6480464 KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein] more ... CTD PMID:31029719 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:733529 6480464 N more ... CTD PMID:15865434 N-acetyl-1,4-benzoquinone imine multiple interactions ISO RGD:733529 6480464 KEAP1 protein inhibits the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine] CTD PMID:19246624 N-acetyl-1,4-benzoquinone imine affects metabolic processing ISO RGD:733529 6480464 N-acetyl-4-benzoquinoneimine affects the metabolism of KEAP1 protein CTD PMID:18785192 N-acetyl-L-cysteine multiple interactions ISO RGD:1605110 6480464 Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein], Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] CTD PMID:11909699 , PMID:19033392 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:733529 6480464 [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein], benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18512965 N-methylnicotinate multiple interactions ISO RGD:1605110 6480464 [trigonelline co-treated with ferric citrate] results in decreased expression of KEAP1 mRNA CTD PMID:29959986 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KEAP1 mRNA CTD PMID:17602206 NADP zwitterion affects abundance ISO RGD:733529 6480464 KEAP1 protein affects the abundance of NADP CTD PMID:21775727 NADP(+) affects abundance ISO RGD:733529 6480464 KEAP1 protein affects the abundance of NADP CTD PMID:21775727 naphthalene-1,2-diol multiple interactions ISO RGD:733529 6480464 Glutathione inhibits the reaction [1, 2-dihydroxynaphthalene analog results in increased metabolism of KEAP1 protein] CTD PMID:25807370 naphthalene-1,2-diol increases metabolic processing ISO RGD:733529 6480464 1, 2-dihydroxynaphthalene analog results in increased metabolism of KEAP1 protein CTD PMID:25807370 naringin multiple interactions ISO RGD:733529 6480464 naringin inhibits the reaction [Doxorubicin results in decreased expression of KEAP1 protein] CTD PMID:36811345 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of KEAP1 mRNA CTD PMID:24136188 nickel atom increases expression ISO RGD:1605110 6480464 Nickel results in increased expression of KEAP1 protein CTD PMID:19033392 nicotinamide multiple interactions EXP 6480464 [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA more ... CTD PMID:21439372 ochratoxin A decreases expression ISO RGD:1605110 6480464 ochratoxin A results in decreased expression of KEAP1 mRNA CTD PMID:32905824 oxidopamine affects response to substance ISO RGD:1605110 6480464 KEAP1 mRNA affects the susceptibility to Oxidopamine CTD PMID:16092930 ozone increases expression ISO RGD:733529 6480464 [Ozone results in increased expression of HIF1A] which results in increased expression of KEAP1 CTD PMID:24040961 ozone multiple interactions ISO RGD:1605110 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [KEAP1 protein results in increased degradation of NFE2L2 protein], [Ozone co-treated with Oxygen] results in increased expression of KEAP1 protein CTD PMID:26270818 , PMID:29864481 p-chloromercuribenzoic acid increases expression ISO RGD:1605110 6480464 p-Chloromercuribenzoic Acid results in increased expression of KEAP1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1605110 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KEAP1 mRNA CTD PMID:27188386 paclitaxel multiple interactions ISO RGD:1605110 6480464 [KEAP1 protein results in decreased stability of NFE2L2 protein] which results in increased susceptibility to Paclitaxel CTD PMID:20530669 paracetamol increases expression ISO RGD:1605110 6480464 Acetaminophen results in increased expression of KEAP1 mRNA CTD PMID:25881548 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of KEAP1 mRNA CTD PMID:33387578 paracetamol affects expression ISO RGD:733529 6480464 Acetaminophen affects the expression of KEAP1 protein CTD PMID:29331651 paracetamol decreases response to substance ISO RGD:733529 6480464 KEAP1 gene mutant form results in decreased susceptibility to Acetaminophen CTD PMID:16293230 , PMID:25499718 paracetamol decreases expression ISO RGD:1605110 6480464 Acetaminophen results in decreased expression of KEAP1 mRNA CTD PMID:21420995 paracetamol increases response to substance ISO RGD:733529 6480464 KEAP1 results in increased susceptibility to Acetaminophen CTD PMID:20404090 paracetamol affects sulfation ISO RGD:733529 6480464 KEAP1 protein affects the sulfation of Acetaminophen CTD PMID:19246624 paracetamol affects glucuronidation ISO RGD:733529 6480464 KEAP1 protein affects the glucuronidation of Acetaminophen CTD PMID:19246624 paracetamol multiple interactions ISO RGD:733529 6480464 ABCC3 protein affects the reaction [KEAP1 protein affects the glucuronidation of Acetaminophen] CTD PMID:19246624 paracetamol affects glutathionylation ISO RGD:733529 6480464 KEAP1 protein affects the glutathionylation of Acetaminophen CTD PMID:19246624 paraquat increases expression EXP 6480464 Paraquat results in increased expression of KEAP1 protein CTD PMID:32064027 paraquat multiple interactions EXP 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] more ... CTD PMID:32064027 pentachlorophenol increases expression ISO RGD:733529 6480464 Pentachlorophenol results in increased expression of KEAP1 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of KEAP1 mRNA CTD PMID:20621739 perillyl aldehyde multiple interactions ISO RGD:1605110 6480464 KEAP1 protein inhibits the reaction [perillaldehyde results in increased expression of TXN mRNA] CTD PMID:19123792 phalloidin multiple interactions ISO RGD:733529 6480464 [KEAP1 gene mutant form results in decreased susceptibility to Phalloidine] which results in decreased expression of CXCL1 mRNA more ... CTD PMID:25280775 phalloidin decreases response to substance ISO RGD:733529 6480464 KEAP1 gene mutant form results in decreased susceptibility to Phalloidine CTD PMID:25280775 phenobarbital multiple interactions ISO RGD:733529 6480464 KEAP1 protein affects the reaction [Phenobarbital results in increased expression of CYP2A5 mRNA] CTD PMID:22859313 phenylarsine oxide affects binding ISO RGD:733529 6480464 oxophenylarsine binds to KEAP1 protein CTD PMID:19786557 , PMID:19808700 phenylmercury acetate increases expression ISO RGD:1605110 6480464 Phenylmercuric Acetate results in increased expression of KEAP1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1605110 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KEAP1 mRNA CTD PMID:27188386 phlorizin increases expression ISO RGD:733529 6480464 Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 pirinixic acid multiple interactions ISO RGD:1605110 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of KEAP1 mRNA CTD PMID:19710929 porphyrins increases expression ISO RGD:1605110 6480464 Porphyrins results in increased expression of KEAP1 mRNA CTD PMID:31385236 potassium dichromate multiple interactions ISO RGD:733529 6480464 Potassium Dichromate affects the localization of and results in decreased ubiquitination of KEAP1 protein, Potassium Dichromate inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:17420218 pterostilbene multiple interactions ISO RGD:733529 6480464 pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:26700463 quercetin multiple interactions ISO RGD:1605110 6480464 Quercetin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KEAP1 protein], Quercetin results in increased metabolism of and results in increased degradation of and results in decreased expression of KEAP1 protein CTD PMID:17462537 , PMID:27050144 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of KEAP1 protein CTD PMID:25339115 quercetin increases expression ISO RGD:733529 6480464 Quercetin results in increased expression of KEAP1 mRNA CTD PMID:23295412 quercetin 3-O-beta-D-glucofuranoside multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 quercetin 3-O-beta-D-glucopyranoside multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 quercitrin increases expression ISO RGD:1605110 6480464 quercitrin results in increased expression of KEAP1 mRNA CTD PMID:25193878 quinolinic acid multiple interactions EXP 6480464 Quinolinic Acid promotes the reaction [DPP3 protein binds to KEAP1 protein] more ... CTD PMID:30876764 reactive oxygen species increases expression ISO RGD:1605110 6480464 Reactive Oxygen Species results in increased expression of KEAP1 mRNA CTD PMID:25800948 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA] more ... CTD PMID:21439372 , PMID:23551926 resveratrol multiple interactions ISO RGD:1605110 6480464 [Resveratrol co-treated with Plant Extracts] inhibits the reaction [[Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of KEAP1 protein] more ... CTD PMID:16948474 more ... rosmarinic acid decreases expression ISO RGD:1605110 6480464 rosmarinic acid results in decreased expression of KEAP1 protein CTD PMID:31610155 rosmarinic acid multiple interactions ISO RGD:1605110 6480464 rosmarinic acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein] CTD PMID:31610155 rotenone decreases response to substance ISO RGD:733529 6480464 KEAP1 gene mutant form results in decreased susceptibility to Rotenone CTD PMID:19167360 rotenone decreases expression ISO RGD:733529 6480464 Rotenone results in decreased expression of KEAP1 mRNA CTD PMID:23186747 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:1605110 6480464 Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein] more ... CTD PMID:19608619 SB 431542 multiple interactions ISO RGD:1605110 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SCH772984 multiple interactions ISO RGD:1605110 6480464 SCH772984 inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 selenium atom increases expression ISO RGD:1605110 6480464 Selenium results in increased expression of KEAP1 mRNA CTD PMID:19244175 silibinin multiple interactions EXP 6480464 Silybin inhibits the reaction [sodium arsenite results in increased expression of KEAP1] CTD PMID:24062023 silicon atom multiple interactions ISO RGD:733529 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of KEAP1 protein] CTD PMID:34252510 silicon atom increases expression ISO RGD:733529 6480464 Silicon results in increased expression of KEAP1 protein CTD PMID:34252510 silicon dioxide multiple interactions ISO RGD:1605110 6480464 tanshinone promotes the reaction [Silicon Dioxide results in decreased expression of KEAP1 protein] CTD PMID:32097614 silicon dioxide decreases expression ISO RGD:1605110 6480464 Silicon Dioxide results in decreased expression of KEAP1 protein CTD PMID:32097614 sirolimus increases expression ISO RGD:1605110 6480464 Sirolimus results in increased expression of KEAP1 protein CTD PMID:29781141 sirolimus multiple interactions ISO RGD:1605110 6480464 Sirolimus inhibits the reaction [Resveratrol inhibits the reaction [Particulate Matter affects the expression of KEAP1 protein]] CTD PMID:29781141 sodium arsenite multiple interactions ISO RGD:1605110 6480464 Decitabine inhibits the reaction [sodium arsenite results in decreased expression of KEAP1 protein] more ... CTD PMID:18417180 more ... sodium arsenite increases methylation ISO RGD:1605110 6480464 sodium arsenite results in increased methylation of KEAP1 promoter CTD PMID:26409248 sodium arsenite affects folding ISO RGD:733529 6480464 sodium arsenite affects the folding of KEAP1 protein CTD PMID:30261176 sodium arsenite decreases expression ISO RGD:1605110 6480464 sodium arsenite results in decreased expression of KEAP1 protein CTD PMID:26409248 , PMID:28229933 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of KEAP1 mRNA CTD PMID:25625412 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of KEAP1 CTD PMID:24062023 sodium arsenite multiple interactions EXP 6480464 silybin inhibits the reaction [sodium arsenite results in increased expression of KEAP1] CTD PMID:24062023 sodium arsenite increases expression ISO RGD:733529 6480464 sodium arsenite results in increased expression of KEAP1 mRNA, sodium arsenite results in increased expression of KEAP1 protein CTD PMID:26371860 sodium arsenite multiple interactions ISO RGD:733529 6480464 ATG7 gene mutant form inhibits the reaction [sodium arsenite results in increased degradation of KEAP1 protein] more ... CTD PMID:16785233 more ... sodium arsenite affects localization ISO RGD:1605110 6480464 sodium arsenite affects the localization of KEAP1 protein CTD PMID:23589329 sodium dichromate decreases expression ISO RGD:733529 6480464 sodium bichromate results in decreased expression of KEAP1 mRNA CTD PMID:22155349 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of KEAP1 mRNA CTD PMID:36736877 sodium fluoride multiple interactions EXP 6480464 Sodium Selenite inhibits the reaction [Sodium Fluoride results in decreased expression of KEAP1 mRNA] CTD PMID:36736877 solanesol multiple interactions ISO RGD:1605110 6480464 solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein], solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:25645596 sterigmatocystin affects expression EXP 6480464 Sterigmatocystin affects the expression of KEAP1 mRNA CTD PMID:34126181 streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA more ... CTD PMID:21439372 more ... streptozocin increases expression ISO RGD:733529 6480464 Streptozocin results in increased expression of KEAP1 mRNA CTD PMID:34896238 streptozocin multiple interactions ISO RGD:733529 6480464 Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA] CTD PMID:34896238 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of KEAP1 mRNA CTD PMID:30817903 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of KEAP1 mRNA, Streptozocin results in increased expression of KEAP1 protein CTD PMID:32662907 , PMID:33639173 sulforaphane increases expression ISO RGD:1605110 6480464 sulforaphane results in increased expression of KEAP1 protein CTD PMID:19033392 sulforaphane decreases expression ISO RGD:1605110 6480464 sulforaphane results in decreased expression of KEAP1 mRNA CTD PMID:35724838 sulforaphane decreases response to substance ISO RGD:1605110 6480464 KEAP1 protein mutant form results in decreased susceptibility to sulforaphane CTD PMID:23589329 sulforaphane multiple interactions ISO RGD:733529 6480464 sulforaphane inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] more ... CTD PMID:15865434 more ... sulforaphane multiple interactions EXP 6480464 sulforaphane promotes the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:22558124 sulforaphane increases response to substance ISO RGD:733529 6480464 KEAP1 protein results in increased susceptibility to sulforaphane CTD PMID:22558124 sulforaphane increases response to substance ISO RGD:1605110 6480464 KEAP1 protein results in increased susceptibility to sulforaphane CTD PMID:22558124 sulforaphane increases metabolic processing ISO RGD:1605110 6480464 sulforaphane results in increased metabolism of KEAP1 protein CTD PMID:21391649 sulforaphane multiple interactions ISO RGD:1605110 6480464 Iodoacetamide inhibits the reaction [sulforaphane results in increased metabolism of KEAP1 protein] more ... CTD PMID:18417180 more ... sulindac decreases expression EXP 6480464 Sulindac results in decreased expression of KEAP1 mRNA CTD PMID:24136188 T-2 toxin decreases expression ISO RGD:1605110 6480464 T-2 Toxin results in decreased expression of KEAP1 mRNA, T-2 Toxin results in decreased expression of KEAP1 protein CTD PMID:35842139 tangeretin multiple interactions EXP 6480464 tangeretin inhibits the reaction [9 more ... CTD PMID:24995432 Tanshinone I multiple interactions ISO RGD:1605110 6480464 tanshinone promotes the reaction [Silicon Dioxide results in decreased expression of KEAP1 protein] CTD PMID:32097614 temozolomide increases expression ISO RGD:1605110 6480464 Temozolomide results in increased expression of KEAP1 mRNA CTD PMID:31758290 tert-butyl hydroperoxide increases expression ISO RGD:1605110 6480464 tert-Butylhydroperoxide results in increased expression of KEAP1 protein CTD PMID:27050144 tert-butyl hydroperoxide multiple interactions ISO RGD:1605110 6480464 Plant Extracts inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KEAP1 protein], Quercetin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KEAP1 protein] CTD PMID:27050144 tetrachloromethane increases expression ISO RGD:733529 6480464 Carbon Tetrachloride results in increased expression of KEAP1 protein CTD PMID:29964319 tetrachloromethane multiple interactions ISO RGD:733529 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein], sulforaphane inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] CTD PMID:29964319 thapsigargin increases expression ISO RGD:1605110 6480464 Thapsigargin results in increased expression of KEAP1 protein CTD PMID:27358234 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of KEAP1 mRNA CTD PMID:34492290 thiophenes multiple interactions ISO RGD:1605110 6480464 Thiophenes inhibits the reaction [KEAP1 gene mutant form promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]] CTD PMID:23906629 Tiron multiple interactions ISO RGD:733529 6480464 1 more ... CTD PMID:33368846 trabectedin increases expression ISO RGD:1605110 6480464 Trabectedin results in increased expression of KEAP1 protein CTD PMID:36396105 trans-anethole multiple interactions EXP 6480464 anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA], anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein] CTD PMID:35430261 trans-piceid multiple interactions ISO RGD:1605110 6480464 polydatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:31705858 trans-piceid multiple interactions ISO RGD:733529 6480464 polydatin inhibits the reaction [TSHR protein results in increased expression of KEAP1 protein] CTD PMID:31705858 trans-rhaponticin multiple interactions EXP 6480464 rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA], rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 tributylstannane decreases expression ISO RGD:733529 6480464 tributyltin results in decreased expression of KEAP1 protein CTD PMID:36858641 Tributyltin oxide affects localization ISO RGD:1605110 6480464 bis(tri-n-butyltin)oxide affects the localization of KEAP1 protein CTD PMID:21601586 tricetin increases expression ISO RGD:1605110 6480464 tricetin results in increased expression of KEAP1 mRNA, tricetin results in increased expression of KEAP1 protein CTD PMID:31176653 trichloroethene multiple interactions ISO RGD:733529 6480464 sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of KEAP1 mRNA] CTD PMID:32073640 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of KEAP1 mRNA CTD PMID:33387578 trichloroethene increases expression ISO RGD:733529 6480464 Trichloroethylene results in increased expression of KEAP1 mRNA CTD PMID:32073640 trichostatin A affects expression ISO RGD:1605110 6480464 trichostatin A affects the expression of KEAP1 mRNA CTD PMID:28542535 trilobatin multiple interactions EXP 6480464 trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 Triptolide decreases expression ISO RGD:1605110 6480464 triptolide results in decreased expression of KEAP1 protein CTD PMID:30682494 triptonide decreases expression ISO RGD:733529 6480464 triptonide results in decreased expression of KEAP1 mRNA CTD PMID:33045310 troglitazone multiple interactions ISO RGD:1605110 6480464 KEAP1 protein promotes the reaction [troglitazone results in increased susceptibility to arsenic trioxide] CTD PMID:22684020 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of KEAP1 mRNA CTD PMID:24136188 valproic acid decreases expression ISO RGD:733529 6480464 Valproic Acid results in decreased expression of KEAP1 mRNA CTD PMID:21427059 valproic acid affects expression ISO RGD:1605110 6480464 Valproic Acid affects the expression of KEAP1 mRNA CTD PMID:25979313 valproic acid decreases expression ISO RGD:1605110 6480464 Valproic Acid results in decreased expression of KEAP1 mRNA CTD PMID:22083351 , PMID:29154799 vitamin D decreases expression ISO RGD:1605110 6480464 Vitamin D results in decreased expression of KEAP1 protein CTD PMID:30698894 XAV939 multiple interactions ISO RGD:1605110 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KEAP1 mRNA, [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA CTD PMID:34480604 zinc atom multiple interactions ISO RGD:733529 6480464 4 more ... CTD PMID:15865434 zinc atom affects binding ISO RGD:733529 6480464 Zinc binds to KEAP1 protein CTD PMID:15865434 zinc dichloride affects folding ISO RGD:733529 6480464 zinc chloride affects the folding of KEAP1 protein CTD PMID:30261176 zinc dichloride multiple interactions ISO RGD:733529 6480464 zinc chloride promotes the reaction [KEAP1 protein binds to KEAP1 protein] CTD PMID:30261176 zinc(0) multiple interactions ISO RGD:733529 6480464 4 more ... CTD PMID:15865434 zinc(0) affects binding ISO RGD:733529 6480464 Zinc binds to KEAP1 protein CTD PMID:15865434
