Egr3 (early growth response 3) - Rat Genome Database

Name: Egr3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Egr3 (early growth response 3) Rattus norvegicus

Analyze

Symbol:

Egr3

Name:

early growth response 3

RGD ID:

2545

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including endothelial cell migration; positive regulation of endothelial cell proliferation; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuromuscular synaptic transmission; peripheral nervous system development; and regulation of T cell differentiation. Predicted to be located in nucleus. Orthologous to human EGR3 (early growth response 3); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-Tetrachlorodibenzofuran; 2-methoxyethanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

early growth response protein 3; EGR-3

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EGR3 (early growth response 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Egr3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Egr3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EGR3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EGR3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EGR3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EGR3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Egr3 (early growth response 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SPATA18 (spermatogenesis associated 18)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	EGR3 (early growth response 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Egr3 (early growth response 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	egr3 (early growth response 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	sr	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	egrh-1	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	egrh-2	Alliance	DIOPT (Hieranoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	STP4	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Saccharomyces cerevisiae (baker's yeast):	STP3	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Xenopus tropicalis (tropical clawed frog):	egr3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	45,150,335 - 45,156,052 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,150,567 - 45,154,627 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,268,727 - 49,271,183 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,380,222 - 50,382,678 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	47,239,546 - 47,242,002 (+)	NCBI	Rnor_WKY
Rnor_6.0	15	51,756,683 - 51,762,080 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	51,756,736 - 51,760,722 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,482,581 - 55,485,350 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	50,477,453 - 50,479,909 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,493,232 - 50,495,689 (+)	NCBI
Celera	15	44,830,934 - 44,833,390 (+)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Ataxia (ISO)

Conotruncal Cardiac Defects (ISO)

COVID-19 (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-pilocarpine (EXP)

(-)-demecolcine (ISO)

(S)-nicotine (ISO)

15-acetyldeoxynivalenol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-methoxyethanol (EXP)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-nitrophenol (ISO)

acrylamide (EXP)

afimoxifene (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antimonite (ISO)

AP20187 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

bathocuproine disulfonic acid (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bexarotene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buta-1,3-diene (ISO)

C.I. Natural Red 20 (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

Calcimycin (ISO)

calcitriol (ISO)

chloroprene (ISO)

choline (ISO)

clomiphene (ISO)

clozapine (ISO)

cocaine (EXP,ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dichloromethane (ISO)

diethylstilbestrol (ISO)

dimethylarsinic acid (ISO)

dioxygen (ISO)

dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO)

divanadium pentaoxide (ISO)

dorsomorphin (ISO)

ellagic acid (ISO)

Enterolactone (ISO)

entinostat (ISO)

estriol (ISO)

estrone (ISO)

ethanol (ISO)

ethylbenzene (ISO)

fenvalerate (EXP)

fluoxetine (EXP)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

hexestrol (ISO)

hydroquinone (ISO)

isotretinoin (ISO)

ivermectin (ISO)

L-methionine (ISO)

leflunomide (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

mestranol (ISO)

methoxychlor (ISO)

methylarsonic acid (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (EXP)

morphine (ISO)

nicotine (ISO)

Nonylphenol (ISO)

o-xylene (ISO)

paracetamol (EXP)

perfluorobutanesulfonic acid (ISO)

perfluorobutyric acid (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluoropentanoic acid (ISO)

phenylmercury acetate (ISO)

phenytoin (EXP)

phorbol 13-acetate 12-myristate (EXP)

pirinixic acid (ISO)

progesterone (ISO)

pyrrolidine dithiocarbamate (ISO)

quercetin (ISO)

raloxifene (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

Shikonin (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

succimer (ISO)

tamibarotene (ISO)

testosterone (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (ISO)

triadimefon (ISO)

trichloroethene (EXP,ISO)

trichostatin A (ISO)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (EXP,ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration involved in sprouting angiogenesis (ISO)

cellular response to fibroblast growth factor stimulus (ISO)

cellular response to vascular endothelial growth factor stimulus (ISO)

endothelial cell chemotaxis (ISO)

negative regulation of apoptotic process (ISO)

neuromuscular synaptic transmission (ISO)

peripheral nervous system development (ISO)

positive regulation of endothelial cell proliferation (ISO)

positive regulation of T cell differentiation in thymus (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of gamma-delta T cell differentiation (ISO)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

metal ion binding (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Egr3/Pilot, a zinc finger transcription factor, is rapidly regulated by activity in brain neurons and colocalizes with Egr1/zif268.	Yamagata K, etal., Learn Mem 1994 Jul-Aug;1(2):140-52.

Additional References at PubMed

PMID:11978828	PMID:12477932	PMID:14560009	PMID:15582775	PMID:16091474	PMID:16901909	PMID:18059339	PMID:21737317	PMID:23332764	PMID:25817788	PMID:26775236	PMID:31858986
PMID:33723811	PMID:36098762

Genomics

Comparative Map Data

Egr3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	45,150,335 - 45,156,052 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,150,567 - 45,154,627 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,268,727 - 49,271,183 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,380,222 - 50,382,678 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	47,239,546 - 47,242,002 (+)	NCBI	Rnor_WKY
Rnor_6.0	15	51,756,683 - 51,762,080 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	51,756,736 - 51,760,722 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,482,581 - 55,485,350 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	50,477,453 - 50,479,909 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,493,232 - 50,495,689 (+)	NCBI
Celera	15	44,830,934 - 44,833,390 (+)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

EGR3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	22,687,659 - 22,693,480 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	8	22,687,659 - 22,693,480 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	22,545,172 - 22,550,993 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	22,601,119 - 22,606,760 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	22,601,118 - 22,606,760	NCBI
Celera	8	21,507,165 - 21,512,936 (-)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	21,088,681 - 21,094,160 (-)	NCBI		HuRef
CHM1_1	8	22,747,408 - 22,752,963 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	22,961,911 - 22,967,732 (-)	NCBI		T2T-CHM13v2.0

Egr3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	70,314,766 - 70,320,062 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	70,314,652 - 70,320,063 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	70,077,317 - 70,082,613 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	70,077,203 - 70,082,614 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	70,477,252 - 70,479,964 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	68,812,525 - 68,815,237 (+)	NCBI		MGSCv36	mm8
Celera	14	67,617,884 - 67,620,596 (+)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI

Egr3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	46,105,447 - 46,108,149 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	46,105,447 - 46,108,149 (-)	NCBI	ChiLan1.0	ChiLan1.0

EGR3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	8	16,919,951 - 16,925,590 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	21,937,516 - 21,943,646 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	18,877,396 - 18,882,874 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	18,877,396 - 18,882,874 (-)	Ensembl	panpan1.1		panPan2

EGR3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	34,591,691 - 34,597,144 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	34,591,863 - 34,594,346 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	35,181,838 - 35,187,272 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	34,801,578 - 34,807,024 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	34,801,876 - 34,806,955 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	34,747,844 - 34,753,287 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	34,602,152 - 34,607,596 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	34,757,654 - 34,763,098 (+)	NCBI		UU_Cfam_GSD_1.0

EGR3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	6,944,935 - 6,948,580 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	6,943,184 - 6,948,507 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	7,423,458 - 7,429,476 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EGR3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	20,767,219 - 20,772,838 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	20,767,224 - 20,772,682 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	21,453,195 - 21,459,987 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Egr3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	18,180,123 - 18,186,196 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	18,180,787 - 18,186,148 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Egr3
12 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	79
Count of miRNA genes:	67
Interacting mature miRNAs:	72
Transcripts:	ENSRNOT00000024067
Prediction methods:	Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
7411725	Strs7	Sensitivity to stroke QTL 7	3.8		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	15	40289901	49308583	Rat
2306968	Anxrr23	Anxiety related response QTL 23	4.83		reflex trait (VT:0001961)	amplitude of the acoustic startle response (CMO:0001520)	15	40631268	46187442	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1				2				13		2
Low	1	17	8		17		1	1	36	8	22	10	1
Below cutoff	1	26	22	14		14	7	10	25	24	15	1	7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252240	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC111804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U12428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000024067 ⟹ ENSRNOP00000024066

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,150,641 - 45,154,627 (+)	Ensembl
Rnor_6.0 Ensembl	15	51,756,978 - 51,759,434 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000077072 ⟹ ENSRNOP00000068798

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,150,641 - 45,154,620 (+)	Ensembl
Rnor_6.0 Ensembl	15	51,756,736 - 51,760,722 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094649 ⟹ ENSRNOP00000095643

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,150,567 - 45,154,627 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000116948 ⟹ ENSRNOP00000089401

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,151,117 - 45,154,627 (+)	Ensembl

RefSeq Acc Id:

NM_017086 ⟹ NP_058782

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,150,883 - 45,153,339 (+)	NCBI
Rnor_6.0	15	51,756,978 - 51,759,434 (+)	NCBI
Rnor_5.0	15	55,482,581 - 55,485,350 (+)	NCBI
RGSC_v3.4	15	50,477,453 - 50,479,909 (+)	RGD
Celera	15	44,830,934 - 44,833,390 (+)	RGD

Sequence:

show sequence

ATGACCGGCAAACTCGCCGAGAAGCTGCCGGTGACCATGAGCAGTTTGCTAAATCAATTGCCTG
ACAATCTGTACCCCGAGGAGATCCCCAGCGCGCTCAACCTCTTCTCCGGCAGCAGTGACTCGGT
AGCCCATTACACTCAGATGGCTACAGAGAATGTGATGGACATCGGTCTGACCAACGAGAAGCCC
AATCCGGAACTCTCTTATTCGGGCTCTTTCCAGCCAGCCCCAGGCAACAAGACCGTGACCTACT
TGGGAAAGTTCGCTTTCGACTCTCCTTCCAACTGGTGCCAGGACAACATCATTAGCCTCATGAG
TGCCGGCATCTTGGGGGTGCCCCCGGCCTCAGGGGCGCTCAGTACGCAGACGACCACGGCTAGC
ATGGTGCAGCCTCCTCAGGGAGACGTGGAGGCCATGTATCCGGCGCTGCCCCCCTATTCCAACT
GCGGCGACCTCTACTCGGAGCCGGTGTCTTTCCACGACCCCCAGGGGAACCCAGGGCTCGCCTA
TTCCCCCCAGGATTACCAATCGGCCAAGCCGGCCTTGGACAGCAATCTTTTCCCCATGATTCCT
GACTACAACCTGTATCACCACCCCAACGACATGGGCTCCATTCCAGAACACAAGCCCTTCCAGG
GCATGGACCCCATTCGGGTCAACCCACCCCCTATTACCCCTCTGGAGACCATCAAGGCCTTCAA
AGACAAGCAGATCCACCCGGGCTTCGGCAGCTTGCCCCAACCGCCGCTTACTCTCAAGCCCATC
CGGCCCCGCAAGTACCCCAATCGGCCTAGCAAGACCCCACTCCACGAGCGGCCCCACGCGTGTC
CCGCGGAAGGCTGTGACCGGCGTTTCAGCCGCTCGGACGAGCTGACCCGGCACCTGCGCATCCA
CACGGGCCACAAGCCCTTCCAGTGTCGGATCTGCATGCGCAGCTTCAGCCGCAGCGACCACCTC
ACTACTCACATCCGCACGCACACCGGGGAGAAGCCCTTTGCCTGTGAGTTCTGTGGGCGCAAGT
TTGCGCGCAGCGACGAGCGCAAGCGCCACGCCAAGATCCACCTCAAGCAAAAGGAGAAGAAGTC
GGAGAAAGGGGGTGCGCCCTCTGCATCCTCGGCGCCCACCGTGTCCCTGGCCCCTGTGGTCACC
ACCTGCGCCTGA

hide sequence

RefSeq Acc Id:

XM_006252240 ⟹ XP_006252302

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,150,335 - 45,156,052 (+)	NCBI
Rnor_6.0	15	51,756,683 - 51,762,080 (+)	NCBI
Rnor_5.0	15	55,482,581 - 55,485,350 (+)	NCBI

Sequence:

show sequence

GCACACGCCCCACCCCACCCCCACGACCCAGCGTCGCACGGCACCAGCTGAGGCACCCGAGAGG
ATTACCCTCTCTGCCCCTCTCCCACCCACCTCCCCAAAAAAGAATAGATCCCCTCCCCTGACCC
ACCCCTTCCCCTTTTCACTCCCCCCTCCCCCCGAACTTTCCCTCTCGCATGCTTTTCCCCTGCA
CCACGGATCGCCTCTCGGATGCCGCTAGCCTGGAAGCTGCGTTAGGAACAGGCGGCGGCGGTGG
CGGCGGCGGCGGCGGTGGCGGCTGTAGCTCGGGAGTGCTATGACCGGCAAACTCGCCGAGAAGC
TGCCGGTGACCATGAGCAGTTTGCTAAATCAATTGCCTGACAATCTGTACCCCGAGGAGATCCC
CAGCGCGCTCAACCTCTTCTCCGGCAGCAGTGACTCGGTAGCCCATTACACTCAGATGGCTACA
GCCTCCCACCCGGGATGGAGCCATGTGCGGCGTGGAGTCCCCACGGTGGGAGAGAGAATGTGAT
GGACATCGGTCTGACCAACGAGAAGCCCAATCCGGAACTCTCTTATTCGGGCTCTTTCCAGCCA
GCCCCAGGCAACAAGACCGTGACCTACTTGGGAAAGTTCGCTTTCGACTCTCCTTCCAACTGGT
GCCAGGACAACATCATTAGCCTCATGAGTGCCGGCATCTTGGGGGTGCCCCCGGCCTCAGGGGC
GCTCAGTACGCAGACGACCACGGCTAGCATGGTGCAGCCTCCTCAGGGAGACGTGGAGGCCATG
TATCCGGCGCTGCCCCCCTATTCCAACTGCGGCGACCTCTACTCGGAGCCGGTGTCTTTCCACG
ACCCCCAGGGGAACCCAGGGCTCGCCTATTCCCCCCAGGATTACCAATCGGCCAAGCCGGCCTT
GGACAGCAATCTTTTCCCCATGATTCCTGACTACAACCTGTATCACCACCCCAACGACATGGGC
TCCATTCCAGAACACAAGCCCTTCCAGGGCATGGACCCCATTCGGGTCAACCCACCCCCTATTA
CCCCTCTGGAGACCATCAAGGCCTTCAAAGACAAGCAGATCCACCCGGGCTTCGGCAGCTTGCC
CCAACCGCCGCTTACTCTCAAGCCCATCCGGCCCCGCAAGTACCCCAATCGGCCTAGCAAGACC
CCACTCCACGAGCGGCCCCACGCGTGTCCCGCGGAAGGCTGTGACCGGCGTTTCAGCCGCTCGG
ACGAGCTGACCCGGCACCTGCGCATCCACACGGGCCACAAGCCCTTCCAGTGTCGGATCTGCAT
GCGCAGCTTCAGCCGCAGCGACCACCTCACTACTCACATCCGCACGCACACCGGGGAGAAGCCC
TTTGCCTGTGAGTTCTGTGGGCGCAAGTTTGCGCGCAGCGACGAGCGCAAGCGCCACGCCAAGA
TCCACCTCAAGCAAAAGGAGAAGAAGTCGGAGAAAGGGGGTGCGCCCTCTGCATCCTCGGCGCC
CACCGTGTCCCTGGCCCCTGTGGTCACCACCTGCGCCTGAGGATCCGCCTCTCAGATCCCTTCT
TTTCCCTTCCAGTGCCTCCTGGCTGGTCGCCTGAAAGCAGCGGGAAAAGCCAGTCACCGAGGCG
CAGGGGCCGCGCCCTGATCTCGCCCTGGACGTGCGGCCCCCTTGCCTCCTCTTCGACGCCCCCT
ATTTCCACCCTTTCACACCGGCCGGCGGTTGGGGGCTAGGGCTAGAGGCACTTTCTCCTTGCTG
CCCCCTCTTAACCAAGGCGTGGGGGTAGAAAGGTGGCGTCTAGCCCGCTTTGTTCAGTTAGGAT
CGCCTTGATCCAGGGGCCGCTGGGCCACGCCAAGGACCTGCGGGGGACTGAAGGCGGGGCCCAT
GCAACCTTCGCCAGACCCAAGCACCTCACTGTTTCCCCCTCCAGTGTCTCCCTGTGTTCCCCCT
CGAACACCCGAGAGGGGGAGGGGGTAAGGAGCGCACCAAAGCGCAGAGCTTGCTGCCCGCCGCA
CGCACGCGCGCTTGCGTGCGGTGATGCGCGCGAGTGTGTGCGTGCTCGCCTGTGTGTAGTGTGC
GTGTGTATGTGTGTGAGTGTGTTGTGTGCGCGCGCACACGTGTGTGTGAGACTCTTGAGCTGAA
CTGGGCTGTGTCTACTCCTAAACTCTTCTTCACAGAAGGTCCCCAAGCCTTTGGGAGATGTCCC
AAGCTAAGGACCAGCAAGTGACCGGAGGAGATGGTCTTCCATCTGCTCCTTAATGTTTCTTACA
GAAATGCCTCGGATGCAGCTACTGCTGCATCGGGTTTGACCCCGTAGAACCCCCTCCCTTTCCG
AGCGCTTCCCTCTTAGGCCTCGGGGCAGTTTGATCTTTGGGGGAGTAAGAGCCACCTTTTTTTT
AAAAAAAGAAATCATTTGCTCAGCCCCACTTTTCAAAACCTGTGTTCTCAAGCTTGCCCTCTGC
CTCTGCCTCCCCCACCCCACCCCGCGCGAGCCCCATCTTCTCCTTTTCCCTCTCAGGTTCGCAC
TGCGTCTCTCAACATCTTTACCCAGAAGGCAGGCCTCAACCACCCAAGTGTTTGTCTCTGTTAC
ATACCCATTCCCCATTACTGGGAAGGCTGGCTCTATTCATTTGCCCTCTGTGATCACCAACACA
ACAGAAGCGAAGTGTATGTATATGATGTTGGCGTGTGTATGTAGATGTATGTGTGTGTTTCTTT
ATACACATATGTTTACATAACATGCACTCTGTATTCCTAGCAAAATCAAATCTAAGGCATTTGG
TTATCCAGTGCAGTGCACTGGAATAAAGAGAATTTGTAGGCATATACAGCTTAAATGATTTATT
TTTATGAAAAGGTAAACTGATGAGATTATTATCTACCTGTGTGTGTGGATATATGTTGCACACG
TGTATATATATGCATACACATTCTGTCAAATTTTCCTCAAAACTAGATGGGGACTTTTGCATTA
ATCTGTGTTGCTGAATGAAGCACATCTGTTTCATGGCCCCATCGCACCTCCCCACCCTACCTCA
CCTCTTCTCAGGAGCCCTCTACCCCAGCTGTCCTGCCCAGCCCTTCCTCACACAGGGTGGCCCT
TTTGACGTGGAGACTTAGAGAAGGGTGCTCCTTGACACAGCTTCCAGCACGGTCTTGATTGAAT
GTACTGTTCCTATTAGCGTCCTTTCTCCCGTGGCCAGTAAGCTGCCCAAAGAGAAGGGACAAAG
GTCTGGAGTTTACAGAATGTCTGTTTTTAAAGTCACTTTATGCGTTTCCCACTTTTTTTTTTAA
TTAAAAAAGCACCGTCTTTTGGTGGTGGATAAATAATACTAAACGGACTACAGTGCAAGGGAGG
AAAGACTCGAAGAGCGGGGATTGTGGGGATCCTGGGGGGATTGTGGGGGATTGTGAGTTTCCAG
GTACTCGGGCTTTTTGTAGAAGGAGAAGTTTGCTAGGAGGGCCCATATTTTTTCAGCTGAAGGG
TAAAATCTTTCTTTGCAGAGACAGTATTTTGCTGAATACTTTTTATAATGTGATGATTATTTAA
AAATACACAATTTGGTCAGTTCAAAGCTGGAAGGAGGAATCAAATATCCTTTAATATTTTTTTC
TTCCTCCTTCTGGAGTATGCATGGCACTGCATGGTAACTCTGACTTTTTCCTTTGTTTTAATAA
AACTGTTCTCAGACATTTAAGCTAAACTAAGAGAAAAAAAAAACTTTGTTGCCAAAAGGTTGTG
CTATCCCAATTTTTTATATGTCTGCATGTTTGAAAACACAAAAAAAAAAAAAAAAAACAAAAGA
AAATGCACTCTAACTTATGTGAACTGAGAGAAAAAAAATCAGGTTTTAAAAAGGAAAAACCCAT
GGGGAATGATATTTTTTGAAAGACTTTTGTATACAGTTGAGTACTTAGAAAAAGACGAACCAGA
TGTAATATATTTTGTGGATGTTTTTATTTCTTGGATTTATAGTACCTTATACTAAGGTTAAAAA
AATGCTTGATATTGTGAAAAGGTGAGATTCTTCACCAACATTTCATTTACTTCTTGTCACATTG
TTATGCCAATATAATATAGTTAATGAAAACAGCATTTTTAAAAGCAATTATTGAAACGGTGTAA
TGTTGTACCATTTGCCCTGTGAGCAAATGCGAATACAGTAAATATATTGTGTTTGCTGACAA

hide sequence

RefSeq Acc Id:

XM_039093001 ⟹ XP_038948929

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,150,894 - 45,156,052 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_058782	(Get FASTA)	NCBI Sequence Viewer
	XP_006252302	(Get FASTA)	NCBI Sequence Viewer
	XP_038948929	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA20818	(Get FASTA)	NCBI Sequence Viewer
	AAH97334	(Get FASTA)	NCBI Sequence Viewer
	EDM02199	(Get FASTA)	NCBI Sequence Viewer
	P43301	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_058782 ⟸ NM_017086

- UniProtKB:

P43301 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MTGKLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVAHYTQMATENVMDIGLTNEKP
NPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTTTAS
MVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIP
DYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPI
RPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHL
TTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGGAPSASSAPTVSLAPVVT
TCA

hide sequence

RefSeq Acc Id:	XP_006252302 ⟸ XM_006252240
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QCU2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPCAAWSPHGGRENVMDIGLTNEKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNI ISLMSAGILGVPPASGALSTQTTTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGN PGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLET IKAFKDKQIHPGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTR HLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQ KEKKSEKGGAPSASSAPTVSLAPVVTTCA hide sequence

RefSeq Acc Id:

ENSRNOP00000068798 ⟸ ENSRNOT00000077072

RefSeq Acc Id:

ENSRNOP00000024066 ⟸ ENSRNOT00000024067

RefSeq Acc Id:	XP_038948929 ⟸ XM_039093001
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QCU2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000089401 ⟸ ENSRNOT00000116948

RefSeq Acc Id:

ENSRNOP00000095643 ⟸ ENSRNOT00000094649

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P43301-F1-model_v2	AlphaFold	P43301	1-387	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699801

Promoter ID:

EPDNEW_R10325

Type:

single initiation site

Name:

Egr3_1

Description:

early growth response 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	51,756,922 - 51,756,982	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2545	AgrOrtholog
BioCyc Gene	G2FUF-13239	BioCyc
Ensembl Genes	ENSRNOG00000017828	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000024066	ENTREZGENE
	ENSRNOP00000024066.3	UniProtKB/TrEMBL
	ENSRNOP00000068798.3	UniProtKB/TrEMBL
	ENSRNOP00000089401.1	UniProtKB/TrEMBL
	ENSRNOP00000095643	ENTREZGENE
	ENSRNOP00000095643.1	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000024067	ENTREZGENE
	ENSRNOT00000024067.6	UniProtKB/TrEMBL
	ENSRNOT00000077072.3	UniProtKB/TrEMBL
	ENSRNOT00000094649	ENTREZGENE
	ENSRNOT00000094649.1	UniProtKB/Swiss-Prot
	ENSRNOT00000116948.1	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7456458	IMAGE-MGC_LOAD
InterPro	EGR_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25148	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114342	IMAGE-MGC_LOAD
NCBI Gene	25148	ENTREZGENE
PANTHER	EARLY GROWTH RESPONSE PROTEIN 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KRUEPPEL-LIKE TRANSCRIPTION FACTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	DUF3446	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Egr3	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A9R7_RAT	UniProtKB/TrEMBL
	A0A8L2QCU2	ENTREZGENE, UniProtKB/TrEMBL
	EGR3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q4V8L1_RAT	UniProtKB/TrEMBL
UniProt Secondary	A0A0G2JTQ1	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Egr3	Early growth response 3			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_regulation	mRNA rapidly and transiently induced in neurons of the hippocampus and cortex by electroconvulsive seizure	727280

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD