Timeless (timeless circadian regulator) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Timeless (timeless circadian regulator) Rattus norvegicus
Analyze
Symbol: Timeless
Name: timeless circadian regulator
RGD ID: 620939
Description: Predicted to enable DNA binding activity and identical protein binding activity. Involved in kidney development; morphogenesis of an epithelium; and positive regulation of circadian rhythm. Acts upstream of or within branching involved in ureteric bud morphogenesis. Located in nucleus. Orthologous to human TIMELESS (timeless circadian regulator); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: rTIM; rTLP; Tim; timeless (Drosophila) homolog; timeless circadian clock; timeless homolog; timeless homolog (Drosophila); timeless-like protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27654,804 - 678,769 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7654,822 - 678,738 (+)Ensembl
Rnor_6.072,643,288 - 2,667,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,643,288 - 2,667,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,622,164 - 2,646,205 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,516,568 - 1,540,512 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,516,569 - 1,540,504 (+)NCBI
Celera7533,427 - 554,888 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
cefaloridine  (EXP)
choline  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
geraniol  (ISO)
L-methionine  (ISO)
menadione  (ISO)
Monobutylphthalate  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:9856465   PMID:9988221   PMID:10231394   PMID:10903565   PMID:12477932   PMID:12875843   PMID:12950082   PMID:15094047   PMID:17102137   PMID:23418588   PMID:23797032   PMID:24489120  
PMID:26344098   PMID:30356214  


Genomics

Comparative Map Data
Timeless
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27654,804 - 678,769 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7654,822 - 678,738 (+)Ensembl
Rnor_6.072,643,288 - 2,667,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,643,288 - 2,667,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,622,164 - 2,646,205 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,516,568 - 1,540,512 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,516,569 - 1,540,504 (+)NCBI
Celera7533,427 - 554,888 (+)NCBICelera
Cytogenetic Map7q11NCBI
TIMELESS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,416,363 - 56,449,426 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1256,416,363 - 56,449,426 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,810,147 - 56,843,210 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,097,174 - 55,129,433 (-)NCBINCBI36hg18NCBI36
Build 341255,097,174 - 55,129,433NCBI
Celera1256,463,518 - 56,496,570 (-)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1253,849,203 - 53,882,241 (-)NCBIHuRef
CHM1_11256,777,536 - 56,810,809 (-)NCBICHM1_1
T2T-CHM13v2.01256,384,058 - 56,417,137 (-)NCBI
Timeless
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,067,932 - 128,088,810 (+)NCBIGRCm39mm39
GRCm39 Ensembl10128,067,934 - 128,088,810 (+)Ensembl
GRCm3810128,232,063 - 128,252,941 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,232,065 - 128,252,941 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,669,119 - 127,689,997 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,641,015 - 127,655,888 (+)NCBImm8
Celera10133,268,115 - 133,283,209 (+)NCBICelera
Celera10130,632,719 - 130,638,534 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.49NCBI
Timeless
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,997,725 - 4,029,766 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,999,143 - 4,029,523 (-)NCBIChiLan1.0ChiLan1.0
TIMELESS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11232,718,649 - 32,750,728 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,718,649 - 32,750,728 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,465,529 - 32,497,581 (+)NCBIMhudiblu_PPA_v0panPan3
TIMELESS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110671,829 - 701,152 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10671,269 - 687,016 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10735,035 - 764,351 (-)NCBI
ROS_Cfam_1.010680,644 - 710,114 (-)NCBI
UMICH_Zoey_3.110657,877 - 687,187 (-)NCBI
UNSW_CanFamBas_1.010901,025 - 930,299 (-)NCBI
UU_Cfam_GSD_1.0101,025,061 - 1,054,020 (-)NCBI
Timeless
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,077,412 - 58,090,044 (+)NCBI
SpeTri2.0NW_004936646780,021 - 792,856 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIMELESS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,371,781 - 52,408,923 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,372,375 - 52,389,284 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037193,573,940 - 193,611,044 (+)NCBIVero_WHO_p1.0
Timeless
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480211,605,116 - 11,629,911 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D7Rat36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27664,270 - 664,437 (+)MAPPERmRatBN7.2
Rnor_6.072,653,138 - 2,653,304NCBIRnor6.0
Rnor_5.072,632,014 - 2,632,180UniSTSRnor5.0
RGSC_v3.471,526,177 - 1,526,344RGDRGSC3.4
RGSC_v3.471,526,178 - 1,526,344UniSTSRGSC3.4
RGSC_v3.171,525,941 - 1,526,374RGD
Celera7540,630 - 540,796UniSTS
SHRSP x BN Map70.04UniSTS
SHRSP x BN Map70.04RGD
Cytogenetic Map7q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:128
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000047241
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 24 30 24 12 24 37 20 29 3
Low 1 19 27 17 7 17 7 9 37 15 12 8 7
Below cutoff 1 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000047241   ⟹   ENSRNOP00000043366
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7654,822 - 678,738 (+)Ensembl
Rnor_6.0 Ensembl72,643,288 - 2,667,321 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083899   ⟹   ENSRNOP00000070516
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7654,822 - 678,738 (+)Ensembl
Rnor_6.0 Ensembl72,645,196 - 2,667,628 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116339   ⟹   ENSRNOP00000085093
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7654,822 - 678,738 (+)Ensembl
RefSeq Acc Id: NM_031340   ⟹   NP_112630
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,866 - 678,766 (+)NCBI
Rnor_6.072,643,288 - 2,667,329 (+)NCBI
Rnor_5.072,622,164 - 2,646,205 (+)NCBI
RGSC_v3.471,516,568 - 1,540,512 (+)RGD
Celera7533,427 - 554,888 (+)RGD
Sequence:
RefSeq Acc Id: XM_039079948   ⟹   XP_038935876
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,804 - 678,769 (+)NCBI
RefSeq Acc Id: XM_039079949   ⟹   XP_038935877
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27656,710 - 678,769 (+)NCBI
RefSeq Acc Id: XM_039079950   ⟹   XP_038935878
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,804 - 678,769 (+)NCBI
RefSeq Acc Id: XM_039079951   ⟹   XP_038935879
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,804 - 678,769 (+)NCBI
RefSeq Acc Id: XM_039079952   ⟹   XP_038935880
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,804 - 678,769 (+)NCBI
RefSeq Acc Id: XM_039079953   ⟹   XP_038935881
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,804 - 678,769 (+)NCBI
RefSeq Acc Id: XM_039079954   ⟹   XP_038935882
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27654,804 - 678,769 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_112630   ⟸   NM_031340
- Sequence:
RefSeq Acc Id: ENSRNOP00000070516   ⟸   ENSRNOT00000083899
RefSeq Acc Id: ENSRNOP00000043366   ⟸   ENSRNOT00000047241
RefSeq Acc Id: XP_038935876   ⟸   XM_039079948
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038935878   ⟸   XM_039079950
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038935879   ⟸   XM_039079951
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038935880   ⟸   XM_039079952
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038935882   ⟸   XM_039079954
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038935881   ⟸   XM_039079953
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038935877   ⟸   XM_039079949
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000085093   ⟸   ENSRNOT00000116339
Protein Domains
TIMELESS   TIMELESS_C

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2Y1-F1-model_v2 AlphaFold Q9Z2Y1 1-1205 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694928
Promoter ID:EPDNEW_R5453
Type:multiple initiation site
Name:Timeless_1
Description:timeless circadian regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,643,264 - 2,643,324EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620939 AgrOrtholog
BioCyc Gene G2FUF-35387 BioCyc
Ensembl Genes ENSRNOG00000031916 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000043366 UniProtKB/TrEMBL
  ENSRNOP00000070516 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000085093 ENTREZGENE
Ensembl Transcript ENSRNOT00000047241 UniProtKB/TrEMBL
  ENSRNOT00000083899 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000116339 ENTREZGENE
IMAGE_CLONE IMAGE:9101557 IMAGE-MGC_LOAD
InterPro Timeless UniProtKB/Swiss-Prot
  Timeless UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Timeless UniProtKB/TrEMBL
  TIMELESS_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83508 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187364 IMAGE-MGC_LOAD
NCBI Gene 83508 ENTREZGENE
PANTHER PTHR22940 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TIMELESS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIMELESS_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Timeless PhenoGen
UniProt B1WBQ6_RAT UniProtKB/TrEMBL
  E9PTS7_RAT UniProtKB/TrEMBL
  Q9Z2Y1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-09 Timeless  timeless circadian regulator  Timeless  timeless circadian clock  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-02 Timeless  timeless circadian clock  Timeless  timeless homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Timeless  timeless homolog (Drosophila)    timeless (Drosophila) homolog  Name updated 1299863 APPROVED
2002-08-07 Timeless  timeless (Drosophila) homolog      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_process full-length mammalian timeless protein expression in the suprachiasmatic nucleus disrupts the neuronal activity rhythms and alters the level of known core clock elements 734503
gene_regulation light pulses that induce phase delays cause elevation in mRNA level in mouse 734504