Alas1 Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALAS1 mRNA] CTD PMID:31150632 Alas1 Rat (1->4)-beta-D-glucan multiple interactions ISO Alas1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ALAS1 mRNA CTD PMID:36331819 Alas1 Rat (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 Alas1 Rat 1,2,4-trichlorobenzene increases activity EXP 6480464 1 more ... CTD PMID:11996131 and PMID:6895089 Alas1 Rat 1,2,4-trichlorobenzene multiple interactions EXP 6480464 Buthionine Sulfoximine inhibits the reaction [1 more ... CTD PMID:11996131 Alas1 Rat 1,2-dimethylhydrazine multiple interactions ISO Alas1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALAS1 mRNA CTD PMID:22206623 Alas1 Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ALAS1 mRNA CTD PMID:15901920 Alas1 Rat 17alpha-ethynylestradiol affects expression ISO Alas1 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of ALAS1 mRNA CTD PMID:17555576 Alas1 Rat 17beta-estradiol affects expression ISO Alas1 (Mus musculus) 6480464 Estradiol affects the expression of ALAS1 mRNA CTD PMID:15598610 Alas1 Rat 17beta-estradiol increases expression ISO Alas1 (Mus musculus) 6480464 Estradiol results in increased expression of ALAS1 mRNA CTD PMID:16684588 Alas1 Rat 17beta-estradiol increases expression ISO ALAS1 (Homo sapiens) 6480464 Estradiol results in increased expression of ALAS1 mRNA CTD PMID:20106945 Alas1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:16984957 Alas1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:20959002 Alas1 Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:31826744 Alas1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO ALAS1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA CTD PMID:19692669 more ... Alas1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Alas1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ALAS1 mRNA CTD PMID:21570461 more ... Alas1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Alas1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA CTD PMID:18163543 more ... Alas1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA CTD PMID:16054898 more ... Alas1 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Alas1 Rat 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:16984957 Alas1 Rat 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:20959002 Alas1 Rat 3,3',4,4',5-pentachlorobiphenyl affects expression ISO ALAS1 (Homo sapiens) 6480464 3 more ... CTD PMID:21703328 Alas1 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression ISO ALAS1 (Homo sapiens) 6480464 3 more ... CTD PMID:19692669 Alas1 Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Alas1 (Mus musculus) 6480464 3 more ... CTD PMID:19467301 Alas1 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ALAS1 mRNA CTD PMID:28628672 Alas1 Rat 4,4'-diaminodiphenylmethane increases expression ISO Alas1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of ALAS1 mRNA CTD PMID:18648102 Alas1 Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ALAS1 mRNA CTD PMID:36041667 Alas1 Rat 4,6-dioxoheptanoic acid multiple interactions ISO ALAS1 (Homo sapiens) 6480464 succinylacetone inhibits the reaction [Heme results in decreased expression of ALAS1 protein] CTD PMID:21659532 Alas1 Rat 4,6-dioxoheptanoic acid multiple interactions ISO Alas1 (Mus musculus) 6480464 NFE2L2 gene mutant form inhibits the reaction [succinylacetone results in increased expression of ALAS1 mRNA] CTD PMID:22859313 Alas1 Rat 4,6-dioxoheptanoic acid increases expression ISO Alas1 (Mus musculus) 6480464 succinylacetone results in increased expression of ALAS1 mRNA CTD PMID:22859313 Alas1 Rat 5-aminolevulinic acid decreases expression ISO Alas1 (Mus musculus) 6480464 Aminolevulinic Acid results in decreased expression of ALAS1 mRNA CTD PMID:22859313 Alas1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ALAS1 mRNA CTD PMID:30047161 Alas1 Rat acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of ALAS1 mRNA CTD PMID:12800193 Alas1 Rat aflatoxin B1 increases methylation ISO ALAS1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ALAS1 promoter CTD PMID:30157460 Alas1 Rat all-trans-retinoic acid multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of ALAS1 mRNA CTD PMID:15894607 Alas1 Rat all-trans-retinoic acid increases expression ISO ALAS1 (Homo sapiens) 6480464 Tretinoin results in increased expression of ALAS1 mRNA CTD PMID:15498508 more ... Alas1 Rat amiodarone increases expression ISO ALAS1 (Homo sapiens) 6480464 Amiodarone results in increased expression of ALAS1 mRNA CTD PMID:19774075 Alas1 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of ALAS1 mRNA CTD PMID:30047161 Alas1 Rat antimycin A decreases expression ISO ALAS1 (Homo sapiens) 6480464 Antimycin A results in decreased expression of ALAS1 mRNA CTD PMID:33512557 Alas1 Rat arsenous acid multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ALAS1 mRNA CTD PMID:15894607 Alas1 Rat arsenous acid increases expression ISO ALAS1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of ALAS1 mRNA CTD PMID:15725085 and PMID:29633893 Alas1 Rat benzo[a]pyrene increases expression ISO ALAS1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of ALAS1 mRNA CTD PMID:20106945 more ... Alas1 Rat benzo[a]pyrene decreases expression ISO ALAS1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ALAS1 mRNA CTD PMID:32234424 Alas1 Rat benzo[a]pyrene increases expression ISO Alas1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ALAS1 mRNA CTD PMID:19770486 more ... Alas1 Rat benzo[b]fluoranthene decreases expression ISO Alas1 (Mus musculus) 6480464 benzo(b)fluoranthene results in decreased expression of ALAS1 mRNA CTD PMID:26377693 Alas1 Rat beta-hexachlorocyclohexane increases expression ISO Alas1 (Mus musculus) 6480464 beta-hexachlorocyclohexane results in increased expression of ALAS1 mRNA CTD PMID:25270620 Alas1 Rat bis(2-ethylhexyl) phthalate increases expression ISO Alas1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of ALAS1 mRNA CTD PMID:19245819 Alas1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Alas1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of ALAS1 mRNA CTD PMID:28085963 Alas1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ALAS1 mRNA CTD PMID:17010207 Alas1 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ALAS1 mRNA CTD PMID:36041667 Alas1 Rat bisphenol A decreases expression ISO Alas1 (Mus musculus) 6480464 bisphenol A results in decreased expression of ALAS1 mRNA CTD PMID:33221593 Alas1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ALAS1 mRNA CTD PMID:34947998 Alas1 Rat bisphenol A affects expression ISO ALAS1 (Homo sapiens) 6480464 bisphenol A affects the expression of ALAS1 mRNA CTD PMID:30903817 Alas1 Rat bisphenol A multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ALAS1 mRNA CTD PMID:28628672 Alas1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ALAS1 mRNA CTD PMID:25181051 more ... Alas1 Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ALAS1 mRNA CTD PMID:36041667 Alas1 Rat bucladesine multiple interactions ISO Alas1 (Mus musculus) 6480464 [NFE2L2 gene mutant form results in increased susceptibility to Bucladesine] which results in increased expression of ALAS1 mRNA CTD PMID:22859313 Alas1 Rat buta-1,3-diene increases expression ISO Alas1 (Mus musculus) 6480464 1 and 3-butadiene results in increased expression of ALAS1 mRNA CTD PMID:29038090 Alas1 Rat butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of ALAS1 mRNA CTD PMID:12800193 Alas1 Rat cadmium dichloride increases expression ISO ALAS1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ALAS1 mRNA CTD PMID:38568856 Alas1 Rat captan increases expression ISO Alas1 (Mus musculus) 6480464 Captan results in increased expression of ALAS1 mRNA CTD PMID:31558096 Alas1 Rat carbon nanotube increases expression ISO Alas1 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of ALAS1 mRNA CTD PMID:25620056 Alas1 Rat carbon nanotube decreases expression ISO Alas1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 Alas1 Rat cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of ALAS1 mRNA CTD PMID:18500788 Alas1 Rat chlorobenzene increases activity EXP 6480464 chlorobenzene results in increased activity of ALAS1 protein CTD PMID:6895089 Alas1 Rat chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of ALAS1 mRNA CTD PMID:30744511 Alas1 Rat chloroprene increases expression ISO Alas1 (Mus musculus) 6480464 Chloroprene results in increased expression of ALAS1 mRNA CTD PMID:23125180 Alas1 Rat chlorpyrifos increases expression ISO Alas1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of ALAS1 mRNA CTD PMID:37019170 Alas1 Rat clofibrate multiple interactions ISO Alas1 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ALAS1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ALAS1 mRNA] CTD PMID:17585979 Alas1 Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of ALAS1 mRNA CTD PMID:11328961 and PMID:12851107 Alas1 Rat clofibrate decreases expression ISO Alas1 (Mus musculus) 6480464 Clofibrate results in decreased expression of ALAS1 mRNA CTD PMID:17585979 Alas1 Rat cobalt dichloride affects expression ISO ALAS1 (Homo sapiens) 6480464 cobaltous chloride affects the expression of ALAS1 mRNA alternative form CTD PMID:19320972 Alas1 Rat copper atom decreases expression ISO Alas1 (Mus musculus) 6480464 Copper results in decreased expression of ALAS1 mRNA CTD PMID:17205981 Alas1 Rat copper(0) decreases expression ISO Alas1 (Mus musculus) 6480464 Copper results in decreased expression of ALAS1 mRNA CTD PMID:17205981 Alas1 Rat copper(II) chloride increases expression ISO ALAS1 (Homo sapiens) 6480464 cupric chloride results in increased expression of ALAS1 mRNA CTD PMID:38568856 Alas1 Rat copper(II) sulfate increases expression ISO ALAS1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of ALAS1 mRNA CTD PMID:19549813 Alas1 Rat curcumin increases expression EXP 6480464 Curcumin results in increased expression of ALAS1 mRNA CTD PMID:18299980 Alas1 Rat cyclosporin A decreases expression ISO Alas1 (Mus musculus) 6480464 Cyclosporine results in decreased expression of ALAS1 mRNA CTD PMID:19770486 Alas1 Rat cyclosporin A increases expression ISO ALAS1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of ALAS1 mRNA CTD PMID:25562108 and PMID:27989131 Alas1 Rat DDT increases expression EXP 6480464 DDT results in increased expression of ALAS1 mRNA CTD PMID:30207508 Alas1 Rat dexamethasone multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ALAS1 mRNA CTD PMID:28628672 Alas1 Rat diarsenic trioxide multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ALAS1 mRNA CTD PMID:15894607 Alas1 Rat diarsenic trioxide increases expression ISO ALAS1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of ALAS1 mRNA CTD PMID:15725085 and PMID:29633893 Alas1 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ALAS1 mRNA CTD PMID:21266533 Alas1 Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of ALAS1 mRNA CTD PMID:17379624 more ... Alas1 Rat diclofenac decreases expression ISO Alas1 (Mus musculus) 6480464 Diclofenac results in decreased expression of ALAS1 mRNA CTD PMID:26934552 Alas1 Rat dicrotophos increases expression ISO ALAS1 (Homo sapiens) 6480464 dicrotophos results in increased expression of ALAS1 mRNA CTD PMID:28302478 Alas1 Rat diethylstilbestrol affects expression EXP 6480464 Diethylstilbestrol affects the expression of ALAS1 mRNA CTD PMID:36653537 Alas1 Rat dioxygen multiple interactions ISO Alas1 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ALAS1 mRNA CTD PMID:30529165 Alas1 Rat diquat increases expression ISO Alas1 (Mus musculus) 6480464 Diquat results in increased expression of ALAS1 mRNA CTD PMID:36851058 Alas1 Rat doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of ALAS1 mRNA CTD PMID:19915844 Alas1 Rat doxorubicin decreases expression ISO ALAS1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of ALAS1 mRNA CTD PMID:29803840 Alas1 Rat elemental selenium increases expression ISO ALAS1 (Homo sapiens) 6480464 Selenium results in increased expression of ALAS1 mRNA CTD PMID:19244175 Alas1 Rat epoxiconazole decreases expression ISO Alas1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of ALAS1 mRNA CTD PMID:35436446 Alas1 Rat ethanol multiple interactions EXP 6480464 [Fish Oils co-treated with Ethanol] results in increased expression of ALAS1 mRNA CTD PMID:17347304 Alas1 Rat ethyl methanesulfonate increases expression ISO ALAS1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of ALAS1 mRNA CTD PMID:23649840 Alas1 Rat etoposide increases expression ISO Alas1 (Mus musculus) 6480464 Etoposide results in increased expression of ALAS1 mRNA CTD PMID:25270620 Alas1 Rat ferroheme b decreases expression ISO ALAS1 (Homo sapiens) 6480464 Heme results in decreased expression of ALAS1 protein CTD PMID:21659532 Alas1 Rat ferroheme b multiple interactions ISO ALAS1 (Homo sapiens) 6480464 MG 262 inhibits the reaction [Heme results in decreased expression of ALAS1 protein] more ... CTD PMID:21659532 Alas1 Rat flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of ALAS1 mRNA CTD PMID:18035473 Alas1 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of ALAS1 mRNA CTD PMID:24136188 Alas1 Rat folic acid multiple interactions ISO Alas1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALAS1 mRNA CTD PMID:22206623 Alas1 Rat folpet increases expression ISO Alas1 (Mus musculus) 6480464 folpet results in increased expression of ALAS1 mRNA CTD PMID:31558096 Alas1 Rat fomesafen increases expression ISO Alas1 (Mus musculus) 6480464 fomesafen results in increased expression of ALAS1 mRNA CTD PMID:12758057 Alas1 Rat genistein increases expression EXP 6480464 Genistein results in increased expression of ALAS1 mRNA CTD PMID:17010207 Alas1 Rat glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of ALAS1 mRNA CTD PMID:24136188 Alas1 Rat gossypol multiple interactions EXP 6480464 chromium protoporphyrin IX promotes the reaction [Gossypol results in increased activity of ALAS1 protein] CTD PMID:15027808 Alas1 Rat gossypol increases activity EXP 6480464 Gossypol results in increased activity of ALAS1 protein CTD PMID:15027808 Alas1 Rat griseofulvin increases expression ISO Alas1 (Mus musculus) 6480464 Griseofulvin results in increased expression of ALAS1 mRNA CTD PMID:10215191 and PMID:15793285 Alas1 Rat griseofulvin multiple interactions ISO Alas1 (Mus musculus) 6480464 6-hydroxy-2 more ... CTD PMID:24523661 Alas1 Rat griseofulvin increases activity ISO Alas1 (Mus musculus) 6480464 Griseofulvin results in increased activity of ALAS1 protein CTD PMID:24523661 Alas1 Rat griseofulvin affects expression ISO Alas1 (Mus musculus) 6480464 Griseofulvin affects the expression of ALAS1 mRNA CTD PMID:12735108 Alas1 Rat heme b decreases expression ISO ALAS1 (Homo sapiens) 6480464 Heme results in decreased expression of ALAS1 protein CTD PMID:21659532 Alas1 Rat heme b multiple interactions ISO ALAS1 (Homo sapiens) 6480464 MG 262 inhibits the reaction [Heme results in decreased expression of ALAS1 protein] more ... CTD PMID:21659532 Alas1 Rat hydrazine increases expression ISO ALAS1 (Homo sapiens) 6480464 hydrazine results in increased expression of ALAS1 mRNA and hydrazine results in increased expression of ALAS1 protein CTD PMID:30517741 Alas1 Rat hyperforin increases expression ISO ALAS1 (Homo sapiens) 6480464 hyperforin results in increased expression of ALAS1 mRNA CTD PMID:24259679 Alas1 Rat indometacin multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ALAS1 mRNA CTD PMID:28628672 Alas1 Rat indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of ALAS1 mRNA CTD PMID:36868495 Alas1 Rat inulin multiple interactions ISO Alas1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ALAS1 mRNA CTD PMID:36331819 Alas1 Rat isoniazide increases expression ISO Alas1 (Mus musculus) 6480464 Isoniazid results in increased expression of ALAS1 protein CTD PMID:27438535 Alas1 Rat isoniazide increases expression ISO ALAS1 (Homo sapiens) 6480464 Isoniazid results in increased expression of ALAS1 protein CTD PMID:30517741 Alas1 Rat isotretinoin decreases expression ISO ALAS1 (Homo sapiens) 6480464 Isotretinoin results in decreased expression of ALAS1 mRNA CTD PMID:20436886 Alas1 Rat ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of ALAS1 mRNA CTD PMID:36653537 Alas1 Rat L-ascorbic acid multiple interactions ISO Alas1 (Mus musculus) 6480464 [Ascorbic Acid co-treated with 6-hydroxy-2 more ... CTD PMID:24523661 Alas1 Rat lead diacetate increases expression ISO ALAS1 (Homo sapiens) 6480464 lead acetate results in increased expression of ALAS1 mRNA CTD PMID:38568856 Alas1 Rat lead(0) increases expression ISO ALAS1 (Homo sapiens) 6480464 Lead results in increased expression of ALAS1 mRNA CTD PMID:37386098 Alas1 Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of ALAS1 mRNA CTD PMID:24136188 Alas1 Rat lipopolysaccharide increases expression ISO Alas1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of ALAS1 mRNA CTD PMID:27339419 Alas1 Rat melatonin multiple interactions ISO Alas1 (Mus musculus) 6480464 Melatonin inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein] CTD PMID:24523661 Alas1 Rat methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of ALAS1 mRNA CTD PMID:30467583 Alas1 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of ALAS1 mRNA CTD PMID:30047161 Alas1 Rat methotrexate affects expression ISO Alas1 (Mus musculus) 6480464 Methotrexate affects the expression of ALAS1 mRNA CTD PMID:18502557 Alas1 Rat methyl methacrylate increases expression ISO Alas1 (Mus musculus) 6480464 Methylmethacrylate results in increased expression of ALAS1 mRNA CTD PMID:16916219 Alas1 Rat methyl methanesulfonate increases expression ISO ALAS1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of ALAS1 mRNA CTD PMID:23649840 Alas1 Rat methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of ALAS1 mRNA CTD PMID:30744511 Alas1 Rat methyltestosterone multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [Methyltestosterone co-treated with Cholic Acids] affects the expression of ALAS1 mRNA CTD PMID:27344345 Alas1 Rat N-methyl-4-phenylpyridinium increases expression ISO ALAS1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ALAS1 mRNA CTD PMID:24810058 Alas1 Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of ALAS1 mRNA CTD PMID:24136188 Alas1 Rat nickel atom decreases expression ISO Alas1 (Mus musculus) 6480464 Nickel results in decreased expression of ALAS1 mRNA CTD PMID:12540486 Alas1 Rat nimesulide increases expression EXP 6480464 nimesulide results in increased expression of ALAS1 mRNA CTD PMID:24136188 Alas1 Rat Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of ALAS1 mRNA CTD PMID:17010207 Alas1 Rat paracetamol multiple interactions ISO Alas1 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ALAS1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ALAS1 mRNA] CTD PMID:17585979 Alas1 Rat paracetamol increases expression ISO ALAS1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of ALAS1 mRNA CTD PMID:21420995 Alas1 Rat paracetamol affects expression ISO Alas1 (Mus musculus) 6480464 Acetaminophen affects the expression of ALAS1 mRNA CTD PMID:15606129 and PMID:17562736 Alas1 Rat paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of ALAS1 mRNA CTD PMID:17366322 Alas1 Rat paraquat multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 Alas1 Rat paraquat increases activity EXP 6480464 Paraquat results in increased activity of ALAS1 protein CTD PMID:12180188 Alas1 Rat pentachlorophenol increases expression ISO Alas1 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of ALAS1 mRNA CTD PMID:23892564 Alas1 Rat perfluorohexanesulfonic acid increases expression ISO ALAS1 (Homo sapiens) 6480464 perfluorohexanesulfonic acid results in increased expression of ALAS1 mRNA CTD PMID:23567314 Alas1 Rat perfluorononanoic acid increases expression ISO ALAS1 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of ALAS1 mRNA CTD PMID:23567314 Alas1 Rat perfluorooctane-1-sulfonic acid increases expression ISO ALAS1 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of ALAS1 mRNA CTD PMID:23567314 more ... Alas1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Alas1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ALAS1 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ALAS1 mRNA CTD PMID:36331819 Alas1 Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ALAS1 mRNA CTD PMID:19162173 and PMID:28511854 Alas1 Rat perfluorooctanoic acid increases expression ISO ALAS1 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of ALAS1 mRNA CTD PMID:37302725 Alas1 Rat phenobarbital decreases expression ISO Alas1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of ALAS1 mRNA CTD PMID:19270015 Alas1 Rat phenobarbital increases expression ISO Alas1 (Mus musculus) 6480464 Phenobarbital results in increased expression of ALAS1 mRNA CTD PMID:19270015 more ... Alas1 Rat phenobarbital affects expression ISO ALAS1 (Homo sapiens) 6480464 Phenobarbital affects the expression of ALAS1 mRNA CTD PMID:19159669 Alas1 Rat phenobarbital increases expression ISO ALAS1 (Homo sapiens) 6480464 Phenobarbital results in increased expression of ALAS1 mRNA CTD PMID:19084549 Alas1 Rat phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of ALAS1 mRNA CTD PMID:19162173 Alas1 Rat phorbol 13-acetate 12-myristate decreases expression ISO ALAS1 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in decreased expression of ALAS mRNA CTD PMID:15797241 Alas1 Rat pirinixic acid multiple interactions ISO ALAS1 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ALAS1 mRNA CTD PMID:19710929 Alas1 Rat pirinixic acid affects expression ISO Alas1 (Mus musculus) 6480464 pirinixic acid affects the expression of ALAS1 mRNA CTD PMID:18445702 and PMID:23811191 Alas1 Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ALAS1 mRNA CTD PMID:19162173 Alas1 Rat pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of ALAS1 mRNA CTD PMID:19162173 Alas1 Rat pregnenolone 16alpha-carbonitrile increases expression ISO Alas1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of ALAS1 mRNA CTD PMID:28903501 Alas1 Rat progesterone increases expression EXP 6480464 Progesterone results in increased expression of ALAS1 mRNA CTD PMID:20726854 Alas1 Rat propiconazole increases expression ISO Alas1 (Mus musculus) 6480464 propiconazole results in increased expression of ALAS1 mRNA CTD PMID:21278054 Alas1 Rat pyridine increases activity EXP 6480464 pyridine results in increased activity of ALAS1 protein CTD PMID:10413312 Alas1 Rat quercetin increases expression ISO ALAS1 (Homo sapiens) 6480464 Quercetin results in increased expression of ALAS1 mRNA CTD PMID:21632981 Alas1 Rat rifampicin increases expression ISO ALAS1 (Homo sapiens) 6480464 Rifampin results in increased expression of ALAS1 mRNA CTD PMID:24259679 and PMID:24552687 Alas1 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of ALAS1 mRNA CTD PMID:28374803 Alas1 Rat S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO ALAS1 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased expression of ALAS1 mRNA CTD PMID:33725128 Alas1 Rat S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 Buthionine Sulfoximine inhibits the reaction [1 more ... CTD PMID:11996131 Alas1 Rat selenium atom increases expression ISO ALAS1 (Homo sapiens) 6480464 Selenium results in increased expression of ALAS1 mRNA CTD PMID:19244175 Alas1 Rat sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of ALAS1 mRNA CTD PMID:15967596 Alas1 Rat sodium arsenite multiple interactions ISO ALAS1 (Homo sapiens) 6480464 sodium arsenite results in increased stability of and results in increased expression of ALAS1 mRNA CTD PMID:25493608 Alas1 Rat sodium arsenite increases expression ISO Alas1 (Mus musculus) 6480464 sodium arsenite results in increased expression of ALAS1 mRNA CTD PMID:33933676 Alas1 Rat sodium arsenite decreases expression ISO Alas1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of ALAS1 mRNA CTD PMID:31532247 Alas1 Rat sodium arsenite increases expression ISO ALAS1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ALAS1 mRNA CTD PMID:25493608 more ... Alas1 Rat sodium dichromate increases expression ISO Alas1 (Mus musculus) 6480464 sodium bichromate results in increased expression of ALAS1 mRNA CTD PMID:31558096 Alas1 Rat streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of ALAS1 mRNA CTD PMID:16684804 Alas1 Rat streptozocin multiple interactions EXP 6480464 vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA] CTD PMID:16684804 Alas1 Rat T-2 toxin increases expression ISO ALAS1 (Homo sapiens) 6480464 T-2 Toxin results in increased expression of ALAS1 mRNA CTD PMID:34581912 Alas1 Rat tamibarotene increases expression ISO ALAS1 (Homo sapiens) 6480464 tamibarotene results in increased expression of ALAS1 mRNA CTD PMID:15498508 Alas1 Rat tamoxifen affects expression ISO Alas1 (Mus musculus) 6480464 Tamoxifen affects the expression of ALAS1 mRNA CTD PMID:20937368 Alas1 Rat tert-butyl hydroperoxide decreases expression ISO ALAS1 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of ALAS1 protein CTD PMID:21659532 Alas1 Rat testosterone increases expression ISO Alas1 (Mus musculus) 6480464 Testosterone results in increased expression of ALAS1 mRNA CTD PMID:20403060 Alas1 Rat tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of ALAS1 mRNA CTD PMID:16239168 Alas1 Rat tetrachloromethane affects expression ISO Alas1 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of ALAS1 mRNA CTD PMID:31919559 Alas1 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ALAS1 mRNA CTD PMID:31150632 Alas1 Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALAS1 mRNA] CTD PMID:31150632 Alas1 Rat tetrachloromethane increases expression ISO Alas1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ALAS1 mRNA CTD PMID:27339419 Alas1 Rat tetracycline decreases expression ISO Alas1 (Mus musculus) 6480464 Tetracycline results in decreased expression of ALAS1 mRNA CTD PMID:24489787 Alas1 Rat thimerosal decreases expression ISO ALAS1 (Homo sapiens) 6480464 Thimerosal results in decreased expression of ALAS1 mRNA CTD PMID:27188386 Alas1 Rat thiram increases expression ISO ALAS1 (Homo sapiens) 6480464 Thiram results in increased expression of ALAS1 mRNA CTD PMID:38568856 Alas1 Rat titanium dioxide decreases expression ISO Alas1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of ALAS1 mRNA CTD PMID:23557971 Alas1 Rat triadimefon increases expression EXP 6480464 triadimefon results in increased expression of ALAS1 mRNA CTD PMID:19409404 Alas1 Rat tributylstannane increases expression ISO Alas1 (Mus musculus) 6480464 tributyltin results in increased expression of ALAS1 mRNA CTD PMID:31939706 Alas1 Rat trichloroethene increases expression ISO Alas1 (Mus musculus) 6480464 Trichloroethylene results in increased expression of ALAS1 mRNA CTD PMID:28973375 Alas1 Rat trichostatin A affects expression ISO ALAS1 (Homo sapiens) 6480464 trichostatin A affects the expression of ALAS1 mRNA CTD PMID:28542535 Alas1 Rat triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of ALAS1 mRNA CTD PMID:30589522 Alas1 Rat triphenyl phosphate affects expression ISO ALAS1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ALAS1 mRNA CTD PMID:37042841 Alas1 Rat triptonide increases expression ISO Alas1 (Mus musculus) 6480464 triptonide results in increased expression of ALAS1 mRNA CTD PMID:33045310 Alas1 Rat urethane increases expression ISO ALAS1 (Homo sapiens) 6480464 Urethane results in increased expression of ALAS1 mRNA CTD PMID:28818685 Alas1 Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of ALAS1 mRNA CTD PMID:24136188 Alas1 Rat valproic acid affects expression ISO Alas1 (Mus musculus) 6480464 Valproic Acid affects the expression of ALAS1 mRNA CTD PMID:17292431 Alas1 Rat valproic acid decreases methylation ISO ALAS1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of ALAS1 gene CTD PMID:29501571 Alas1 Rat valproic acid decreases expression ISO ALAS1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ALAS1 protein CTD PMID:29501571 Alas1 Rat valproic acid increases methylation ISO ALAS1 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ALAS1 gene CTD PMID:29154799 Alas1 Rat valproic acid increases expression ISO ALAS1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ALAS1 mRNA CTD PMID:29154799 and PMID:29501571 Alas1 Rat vanadyl sulfate multiple interactions EXP 6480464 vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA] CTD PMID:16684804 Alas1 Rat vorinostat increases expression ISO ALAS1 (Homo sapiens) 6480464 vorinostat results in increased expression of ALAS1 mRNA CTD PMID:22083351 Alas1 Rat zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ALAS1 mRNA CTD PMID:12672911 Alas1 Rat zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ALAS1 mRNA CTD PMID:12672911