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Gene: Alas1 (aminolevulinic acid synthase 1) Mus musculus
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Symbol: Alas1
Name: aminolevulinic acid synthase 1
Description: ENCODES a protein that exhibits 5-aminolevulinate synthase activity (ortholog); identical protein binding (ortholog); INVOLVED IN biosynthetic process (inferred); heme biosynthetic process (inferred); porphyrin-containing compound metabolic process (inferred); PARTICIPATES IN acute intermittent porphyria pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; ASSOCIATED WITH embryonic growth retardation; embryonic lethality between implantation and placentation, complete penetrance; ASSOCIATED WITH Diabetes Mellitus, Experimental (ortholog); porphyria (ortholog); pulmonary hypertension (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; Alas-1; Alas-h; ALAS-N; aminolevulinate synthase H; delta-ALA synthase 1; delta-aminolevulinate synthase 1; succinyl-CoA: glycine C-succinyl transferase
Orthologs:
Homo sapiens (human) : ALAS1 (5'-aminolevulinate synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Alas1 (5'-aminolevulinate synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alas1 (5'-aminolevulinate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALAS1 (5'-aminolevulinate synthase 1)
Canis lupus familiaris (dog) : ALAS1 (5'-aminolevulinate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alas1 (5'-aminolevulinate synthase 1)
Sus scrofa (pig) : ALAS1 (aminolevulinate, delta-, synthase 1 pseudogene)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389106,233,455 - 106,247,954 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379106,135,786 - 106,150,285 (-)NCBIGRCm37mm9NCBIm37
MGSCv369106,092,028 - 106,105,957 (-)NCBImm8
Celera9105,859,658 - 105,874,969 (-)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Alas1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68573
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.