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Gene: Alas1 (aminolevulinic acid synthase 1) Mus musculus
Symbol: Alas1
Name: aminolevulinic acid synthase 1
Description: ENCODES a protein that exhibits 5-aminolevulinate synthase activity (ortholog); identical protein binding (ortholog); INVOLVED IN biosynthetic process (inferred); heme biosynthetic process (inferred); porphyrin-containing compound metabolic process (inferred); PARTICIPATES IN acute intermittent porphyria pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; ASSOCIATED WITH embryonic growth retardation; embryonic lethality between implantation and placentation, complete penetrance; ASSOCIATED WITH Diabetes Mellitus, Experimental (ortholog); porphyria (ortholog); pulmonary hypertension (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; Alas-1; Alas-h; ALAS-N; aminolevulinate synthase H; delta-ALA synthase 1; delta-aminolevulinate synthase 1; succinyl-CoA: glycine C-succinyl transferase
Homo sapiens (human) : ALAS1 (5'-aminolevulinate synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Alas1 (5'-aminolevulinate synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alas1 (5'-aminolevulinate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALAS1 (5'-aminolevulinate synthase 1)
Canis lupus familiaris (dog) : ALAS1 (5'-aminolevulinate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alas1 (5'-aminolevulinate synthase 1)
Sus scrofa (pig) : ALAS1 (aminolevulinate, delta-, synthase 1 pseudogene)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389106,233,455 - 106,247,954 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379106,135,786 - 106,150,285 (-)NCBIGRCm37mm9NCBIm37
MGSCv369106,092,028 - 106,105,957 (-)NCBImm8
Celera9105,859,658 - 105,874,969 (-)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Alas1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68573
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.