Icam1 (intercellular adhesion molecule 1) - Rat Genome Database

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Gene: Icam1 (intercellular adhesion molecule 1) Rattus norvegicus
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Symbol: Icam1
Name: intercellular adhesion molecule 1
RGD ID: 2857
Description: Enables integrin binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and gonad development. Located in cell surface; extracellular space; and plasma membrane. Used to study diabetic angiopathy; mesenteric vascular occlusion; nephritis; pre-eclampsia; and uveitis. Biomarker of several diseases, including cerebrovascular disease (multiple); colitis (multiple); glucose metabolism disease (multiple); kidney failure (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); biliary atresia; diabetic retinopathy; inflammatory bowel disease (multiple); and liver cirrhosis. Orthologous to human ICAM1 (intercellular adhesion molecule 1); PARTICIPATES IN pro-inflammatory cytokine mediated pathway; eicosanoid signaling pathway; influenza A pathway; INTERACTS WITH (+)-schisandrin B; (+)-Tetrandrine; (S)-colchicine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD54; ICAM; ICAM-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2819,553,063 - 19,565,438 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl819,553,645 - 19,565,438 (+)Ensembl
Rnor_6.0822,035,287 - 22,047,049 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,035,256 - 22,047,059 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,092,155 - 22,103,917 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,040,177 - 20,051,939 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1820,040,176 - 20,051,939 (+)NCBI
Celera820,948,090 - 20,959,852 (+)NCBICelera
RH 3.4 Map8206.11RGD
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (IEP,IMP)
acute kidney failure  (IEP)
Acute Lung Injury  (IEP,ISO)
acute necrotizing pancreatitis  (IEP)
adult respiratory distress syndrome  (ISO)
alcoholic hepatitis  (ISO)
allergic bronchopulmonary aspergillosis  (ISO)
allergic conjunctivitis  (ISO)
allergic disease  (ISO)
Alzheimer's disease  (ISO)
Animal Hepatitis  (ISO)
arteriosclerosis  (ISO)
asthma  (IEP,ISO)
atherosclerosis  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
Bacteremia  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
biliary atresia  (ISO)
Brain Death  (IEP)
brain edema  (IEP)
brain infarction  (ISO)
Brain Injuries  (IEP)
Brain Injuries, Traumatic  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiectasis  (ISO)
bronchus carcinoma  (ISO)
bullous pemphigoid  (ISO)
cardiovascular system disease  (ISO)
Carotid Artery Injuries  (IEP)
cerebral infarction  (IEP)
Chemical and Drug Induced Liver Injury  (IEP)
chlamydia  (ISO)
cholestasis  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (IEP)
Chronic Bronchitis  (IEP)
chronic obstructive pulmonary disease  (ISO)
chronic ulcer of skin  (ISO)
colitis  (IEP)
Colonic Neoplasms  (ISO)
contact dermatitis  (ISO)
Crohn's disease  (ISO)
Delayed Hypersensitivity  (ISO)
dermatitis  (ISO)
diabetes mellitus  (ISO)
diabetic angiopathy  (IDA,ISO)
Diabetic Nephropathies  (IDA,ISO)
diabetic retinopathy  (IEP,ISO)
Diaphragmatic Hernia  (ISO)
diffuse large B-cell lymphoma  (ISO)
end stage renal disease  (IEP)
Endotoxemia  (IEP)
Enteritis  (IEP)
Eosinophilic Myocarditis  (ISO)
Experimental Autoimmune Myocarditis  (IEP)
Experimental Autoimmune Uveitis  (ISO)
Experimental Autoimmune Uveoretinitis  (IMP)
Experimental Colitis  (IMP)
Experimental Diabetes Mellitus  (IEP,ISO)
Fibrosis  (IEP)
gestational diabetes  (ISO)
Graft vs Host Disease  (ISO)
Graves Ophthalmopathy  (ISO)
Graves' disease  (ISO)
Hashimoto Disease  (ISO)
Hearing Loss, Noise-Induced  (IMP)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Hodgkin's lymphoma  (ISO)
Hypercholesterolemia  (ISO)
hyperglycemia  (IEP)
hyperhomocysteinemia  (IEP)
Hyperoxia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (IEP)
idiopathic interstitial pneumonia  (ISO)
Inflammation  (IDA,IEP,ISO)
inflammatory bowel disease  (ISO)
Insulin Resistance  (ISO)
Intestinal Reperfusion Injury  (IEP)
Intimal Hyperplasia  (IMP)
iridocyclitis  (ISO)
Jaundice  (IEP)
Kidney Neoplasms  (ISO)
leukostasis  (ISO)
liver cirrhosis  (ISO)
Liver Injury  (IEP)
Liver Reperfusion Injury  (IEP,IMP)
localized scleroderma  (ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (IEP)
Lymphatic Metastasis  (ISO)
Lymphocytic Myocarditis  (ISO)
malaria  (ISO)
melanoma  (ISO)
Mercury Poisoning  (IEP)
mesenteric vascular occlusion  (IMP)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
Mouth Neoplasms  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (IEP,ISO)
multiple sclerosis  (ISO)
myocardial infarction  (IEP,ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (IEP,ISO)
myocarditis  (ISO)
Nasal Polyps  (ISO)
Neoplasm Metastasis  (ISO)
neovascular inflammatory vitreoretinopathy  (ISO)
nephritis  (IMP)
nephrosis  (ISO)
newborn respiratory distress syndrome  (IEP,ISO)
non-Hodgkin lymphoma  (ISO)
obesity  (IEP,ISO)
obstructive sleep apnea  (ISO)
otitis media  (ISO)
ovarian cancer  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (IEP,ISO)
paracoccidioidomycosis  (ISO)
Perennial Allergic Rhinitis  (ISO)
peripheral nervous system disease  (ISO)
pleurisy  (ISO)
pneumonia  (IEP)
pre-eclampsia  (IMP)
primary biliary cholangitis  (ISO)
Primary Graft Dysfunction  (IMP)
Prinzmetal angina  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (IEP)
Pseudomonas Aeruginosa Keratitis  (ISO)
psoriasis  (ISO)
pulmonary fibrosis  (IEP)
pulmonary hypertension  (ISO)
Reperfusion Injury  (ISO)
respiratory syncytial virus infectious disease  (ISO)
Retina Reperfusion Injury  (IEP,IMP)
retinal disease  (ISO)
retinopathy of prematurity  (IEP)
rheumatic fever  (ISO)
rheumatic myocarditis  (ISO)
sciatic neuropathy  (IEP)
Seasonal Allergic Rhinitis  (ISO)
Sepsis  (IEP)
Sjogren's syndrome  (ISO)
skin melanoma  (ISO)
Spinal Cord Injuries  (IMP)
Stroke  (IMP,ISO)
Subarachnoid Hemorrhage  (IEP)
systemic scleroderma  (ISO)
transient cerebral ischemia  (IEP)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (IEP,ISO)
ulcerative colitis  (IEP,ISO)
uremia  (ISO)
ureteral obstruction  (IEP)
urinary bladder cancer  (ISO)
urticaria  (ISO)
uveitis  (IDA,ISO)
venous insufficiency  (ISO)
Viral Myocarditis  (ISO)
Wounds and Injuries  (ISO)
Wounds, Penetrating  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(+)-taxifolin  (ISO)
(+)-Tetrandrine  (EXP)
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
(20S)-ginsenoside Rh1  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid  (ISO)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (ISO)
(R)-linalyl acetate  (ISO)
(R)-mevalonic acid  (ISO)
(R)-noradrenaline  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (EXP)
(S)-nicotine  (EXP)
1'-acetoxychavicol acetate  (ISO)
1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane  (ISO)
1,10-phenanthroline  (ISO)
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose  (ISO)
1,8-cineole  (EXP)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-dinitroiodobenzene  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-arachidonoylglycerol  (ISO)
2-butoxyethanol  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
22-Hydroxycholesterol  (ISO)
26-hydroxycholesterol  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (ISO)
3-methylcholanthrene  (EXP)
3-phenylprop-2-enal  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-methylhistamine  (ISO)
5-(1,4-diazepane-1-sulfonyl)isoquinoline  (EXP)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
7,12-dimethyltetraphene  (EXP)
7-ketocholesterol  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acetic acid  (EXP)
acetylsalicylic acid  (EXP,ISO)
acrylamide  (EXP)
acteoside  (ISO)
aflatoxin B1  (ISO)
albendazole  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
alginic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allicin  (ISO)
alloxan  (ISO)
alpha-naphthoflavone  (EXP)
aluminium hydroxide  (ISO)
aluminium oxide  (ISO)
AM-251  (ISO)
amiodarone  (ISO)
amlodipine  (EXP)
ammonium acetate  (EXP)
ammonium chloride  (EXP)
anagliptin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
apocynin  (ISO)
argatroban  (ISO)
aripiprazole  (ISO)
aristolochic acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (ISO)
asbestos  (ISO)
aspalathin  (ISO)
astemizole  (ISO)
atazanavir sulfate  (ISO)
atorvastatin calcium  (EXP,ISO)
ATP  (ISO)
atropine  (ISO)
Bandrowski's base  (ISO)
beclomethasone  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beryllium sulfate  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-eudesmol  (ISO)
bezafibrate  (ISO)
bicalutamide  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
bongkrekic acid  (ISO)
bortezomib  (ISO)
bromobenzene  (ISO)
bucladesine  (ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcium dichloride  (ISO)
candesartan  (EXP)
Candesartan cilexetil  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
capsazepine  (ISO)
capsiate  (ISO)
carbamazepine  (ISO)
carbon monoxide  (EXP,ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (EXP)
carnosine  (ISO)
Carnosol  (ISO)
carrageenan  (EXP,ISO)
CDP-choline  (EXP)
cefaloridine  (EXP)
celastrol  (ISO)
celecoxib  (ISO)
cerivastatin  (ISO)
ceruletide  (ISO)
chenodeoxycholic acid  (ISO)
chlordecone  (ISO)
chloroform  (EXP)
chloroquine  (ISO)
cholesterol  (EXP)
choline  (ISO)
chromium atom  (EXP)
chromium(3+) trichloride  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
chrysin  (ISO)
ciglitazone  (ISO)
cimetidine  (ISO)
cisplatin  (ISO)
citral  (ISO)
citric acid  (ISO)
clobetasol  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP,ISO)
clopidogrel  (ISO)
cloricromen  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP)
colforsin daropate hydrochloride  (ISO)
conjugated linoleic acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
Curcumol  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cytochalasin D  (ISO)
D-glucose  (EXP,ISO)
D-mannitol  (ISO)
dabrafenib  (ISO)
daunorubicin  (EXP)
Decursin  (ISO)
Deguelin  (ISO)
delta-tocotrienol  (ISO)
deoxycholic acid  (ISO)
Deoxycorticosterone acetate  (EXP)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
desflurane  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibenziodolium  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (EXP,ISO)
dicloxacillin  (ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diethyl phthalate  (ISO)
diethyldithiocarbamic acid  (ISO)
diethylstilbestrol  (ISO)
Dimaprit  (ISO)
dimethyl fumarate  (ISO)
dimethyl sulfoxide  (ISO)
Diosbulbin B  (ISO)
dioscin  (EXP)
dioxygen  (EXP,ISO)
diphenylmethane-4,4'-diisocyanate  (ISO)
dipyridamole  (ISO)
disodium selenite  (ISO)
donepezil hydrochloride  (ISO)
doramapimod  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
edaravone  (EXP)
emodin  (EXP)
enalapril  (EXP,ISO)
endosulfan  (EXP)
entinostat  (ISO)
ergosterol  (EXP)
erythromycin A  (ISO)
estrone  (EXP)
ethanol  (ISO)
Ethyl icosapentate  (ISO)
etoricoxib  (ISO)
eugenol  (ISO)
Evodiamine  (ISO)
famotidine  (ISO)
farnesol  (ISO)
farnesyl diphosphate  (ISO)
fasudil hydrochloride  (EXP)
fenamidone  (ISO)
fenbuconazole  (ISO)
fenofibrate  (ISO)
ferric oxide  (ISO)
ferrous oxide  (ISO)
Fexofenadine hydrochloride  (ISO)
filipin III  (ISO)
flavonoids  (ISO)
fluoranthene  (ISO)
flurbiprofen  (EXP)
fluticasone  (ISO)
fluvoxamine  (EXP,ISO)
formaldehyde  (EXP,ISO)
fructose  (EXP,ISO)
fulvestrant  (EXP,ISO)
fumaric acid  (ISO)
gadolinium trichloride  (ISO)
galangin  (ISO)
gallic acid  (EXP)
Garcinol  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP,ISO)
geranial  (ISO)
geraniol  (EXP,ISO)
ginsenoside C-K  (ISO)
glafenine  (EXP)
gliclazide  (EXP)
glucose  (EXP,ISO)
glutathione  (ISO)
graphite  (EXP)
GW 3965  (ISO)
GW 4064  (ISO)
GW 501516  (ISO)
GW 6471  (ISO)
halothane  (EXP,ISO)
helenalin  (ISO)
herbimycin  (ISO)
hesperetin  (EXP)
hesperidin  (ISO)
hexachlorobenzene  (EXP)
hexadecanoic acid  (ISO)
hexamethylene diisocyanate  (ISO)
histamine  (ISO)
Honokiol  (EXP)
hydralazine  (ISO)
hydrazines  (ISO)
hydrogen chloride  (EXP,ISO)
hydrogen peroxide  (ISO)
hydroxamic acid  (EXP)
hydroxysafflor yellow A  (EXP,ISO)
hydroxytyrosol  (ISO)
hyperforin  (ISO)
ibuprofen  (ISO)
icatibant  (EXP)
imidurea  (ISO)
imiquimod  (ISO)
immunological adjuvant  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
indoxyl sulfate  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
Isoangustone A  (ISO)
isocarbophos  (EXP)
isoflurane  (EXP,ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
jaspamide  (ISO)
kaempferol  (ISO)
kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside  (ISO)
ketamine  (ISO)
ketorolac  (EXP)
ketotifen  (ISO)
L-ascorbic acid  (ISO)
L-cysteine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
leukotriene D4  (ISO)
levofloxacin  (ISO)
linalool  (ISO)
linalyl acetate  (ISO)
lipopolysaccharide  (EXP,ISO)
lipoxin A4  (ISO)
lithium chloride  (ISO)
lithocholic acid  (ISO)
lopinavir  (ISO)
losartan  (ISO)
lucanthone  (ISO)
luteolin  (ISO)
LY294002  (ISO)
lycopene  (ISO)
lysophosphatidylcholine  (ISO)
maneb  (ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (ISO)
medroxyprogesterone acetate  (ISO)
melittin  (ISO)
melphalan  (ISO)
mercury dichloride  (EXP,ISO)
metformin  (EXP)
Methanandamide  (ISO)
methapyrilene  (EXP,ISO)
methotrexate  (EXP,ISO)
methyl beta-cyclodextrin  (ISO)
methylene blue  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
Methylthiouracil  (ISO)
mifepristone  (EXP,ISO)
minocycline  (EXP)
miquelianin  (ISO)
Mizolastine  (ISO)
monocrotaline  (ISO)
morphine  (EXP)
myricitrin  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naloxone  (EXP)
Nandrolone decanoate  (EXP)
naringin  (ISO)
nebivolol  (ISO)
nefazodone  (EXP)
neocuproine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (EXP,ISO)
niclosamide  (EXP,ISO)
nicotinamide  (ISO)
nicotine  (EXP)
nicotinic acid  (EXP,ISO)
nimesulide  (ISO)
nitric oxide  (ISO)
nitrofen  (EXP)
nitrogen dioxide  (ISO)
notoginsenoside R1  (ISO)
NS-398  (ISO)
NSC 23766  (ISO)
nystatin  (ISO)
o-anisidine  (ISO)
ochratoxin A  (ISO)
octanoic acid  (ISO)
olaparib  (ISO)
oleanolic acid  (ISO)
oleuropein  (ISO)
oxaliplatin  (EXP)
oxidopamine  (EXP)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
p-cresol  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
paricalcitol  (ISO)
parthenolide  (ISO)
pelargonidin  (ISO)
pentanal  (ISO)
pentobarbital  (ISO)
Pentoxifylline  (EXP)
peptidoglycan  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perindopril  (ISO)
phenanthrene  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramidon  (EXP)
phthalic anhydride  (ISO)
pimecrolimus  (ISO)
pioglitazone  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
pluronic P-123  (ISO)
Poloxamer  (ISO)
polymyxin B2  (ISO)
polyphosphates  (ISO)
potassium chloride  (ISO)
potassium dichromate  (ISO)
PR-39  (ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
propiconazole  (ISO)
prostaglandin E2  (ISO)
puerarin  (ISO)
pyrene  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
Quinupristin-dalfopristin  (ISO)
rac-lactic acid  (ISO)
ranitidine  (ISO)
reactive oxygen species  (ISO)
Rebamipide  (ISO)
resolvin D1  (ISO)
resolvin D2  (ISO)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
ribavirin  (ISO)
rimonabant  (ISO)
ritonavir  (ISO)
romidepsin  (ISO)
rotenone  (EXP,ISO)
Ruscogenin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salicylic acid  (ISO)
sarpogrelate  (ISO)
saxagliptin  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium cholate  (ISO)
sodium dichromate  (EXP)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
Sodium salicylate  (ISO)
sodium stibogluconate  (ISO)
Soman  (EXP,ISO)
stattic  (ISO)
streptozocin  (EXP,ISO)
succimer  (ISO)
sulfasalazine  (EXP,ISO)
sulfates  (ISO)
sulforaphane  (EXP,ISO)
sulfur dioxide  (EXP)
sulindac  (ISO)
tacrolimus hydrate  (EXP,ISO)
taurine  (EXP)
tauro-beta-muricholic acid  (ISO)
taurocholic acid  (EXP,ISO)
telmisartan  (EXP,ISO)
tepoxalin  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
tetrathiomolybdate(2-)  (ISO)
thalidomide  (EXP,ISO)
thioacetamide  (EXP,ISO)
thiram  (ISO)
tibolone  (ISO)
titanium atom  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trierixin  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tropisetron  (EXP)
trovafloxacin  (ISO)
ursolic acid  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vancomycin  (ISO)
vincaleukoblastine  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (EXP,ISO)
vitamin E  (ISO)
vorinostat  (ISO)
wortmannin  (EXP,ISO)
xanthohumol  (ISO)
Y-27632  (EXP,ISO)
zerumbone  (ISO)
zileuton  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc oxide  (ISO)
zinc protoporphyrin  (EXP,ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)
zomepirac  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute inflammatory response to antigenic stimulus  (IMP)
adhesion of symbiont to host  (ISO)
cell adhesion  (IBA,ISO)
cell adhesion mediated by integrin  (ISO)
cell aging  (IEP)
cell-cell adhesion  (IDA,IMP)
cellular response to alkaloid  (IEP)
cellular response to amyloid-beta  (ISO)
cellular response to dexamethasone stimulus  (IEP)
cellular response to glucose stimulus  (IEP,ISO)
cellular response to hypoxia  (IEP)
cellular response to interferon-gamma  (IEP)
cellular response to interleukin-1  (IEP)
cellular response to interleukin-6  (IEP)
cellular response to leukemia inhibitory factor  (ISO)
cellular response to lipopolysaccharide  (IEP)
cellular response to nutrient levels  (IEP)
cellular response to organic substance  (IEP)
cellular response to tumor necrosis factor  (IEP)
establishment of endothelial barrier  (ISO)
establishment of endothelial intestinal barrier  (IMP)
establishment of Sertoli cell barrier  (IDA)
leukocyte cell-cell adhesion  (ISO)
leukocyte migration  (ISO,TAS)
membrane to membrane docking  (ISO)
negative regulation of calcium ion transport  (IDA)
negative regulation of endothelial cell apoptotic process  (ISO)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
ovarian follicle development  (IEP)
positive regulation of actin filament polymerization  (IDA)
positive regulation of cellular extravasation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of GTPase activity  (IDA)
positive regulation of leukocyte adhesion to vascular endothelial cell  (IMP)
positive regulation of NF-kappaB transcription factor activity  (IMP)
positive regulation of nitric oxide biosynthetic process  (IMP)
positive regulation of peptidyl-tyrosine phosphorylation  (IDA)
positive regulation of vasoconstriction  (IMP)
receptor-mediated virion attachment to host cell  (ISO)
regulation of cell shape  (IMP)
regulation of ruffle assembly  (ISO)
response to amino acid  (IEP)
response to amphetamine  (IEP)
response to copper ion  (IEP)
response to ethanol  (IEP)
response to gonadotropin  (IEP)
response to hypoxia  (IEP)
response to insulin  (IEP)
response to ionizing radiation  (IEP)
response to lipopolysaccharide  (IEP)
response to organic cyclic compound  (IEP)
response to sulfur dioxide  (IEP)
response to xenobiotic stimulus  (IEP)
sensory perception of sound  (IMP)
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell  (ISO)
T cell antigen processing and presentation  (ISO)
T cell extravasation  (ISO)

Cellular Component

Molecular Function

References

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Additional References at PubMed
PMID:1448173   PMID:2477710   PMID:2479693   PMID:2538243   PMID:8562500   PMID:9290466   PMID:10528208   PMID:10601245   PMID:10903502   PMID:11078691   PMID:11880280   PMID:12061795  
PMID:12082081   PMID:12126535   PMID:12131776   PMID:12133872   PMID:12196270   PMID:12208882   PMID:12675845   PMID:12763482   PMID:12902516   PMID:14580850   PMID:14973438   PMID:15198126  
PMID:15201548   PMID:15215195   PMID:15240134   PMID:15249579   PMID:15489334   PMID:15598973   PMID:15624701   PMID:15742404   PMID:15754395   PMID:15860735   PMID:15946255   PMID:16199477  
PMID:16229173   PMID:16286275   PMID:16328103   PMID:16343550   PMID:16489637   PMID:16512644   PMID:16629649   PMID:16647725   PMID:16809613   PMID:16874877   PMID:16901988   PMID:16937496  
PMID:16973387   PMID:17033093   PMID:17336102   PMID:17344467   PMID:17369472   PMID:17590487   PMID:17670746   PMID:17690033   PMID:17991463   PMID:18326823   PMID:18379124   PMID:18400211  
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Genomics

Comparative Map Data
Icam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2819,553,063 - 19,565,438 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl819,553,645 - 19,565,438 (+)Ensembl
Rnor_6.0822,035,287 - 22,047,049 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,035,256 - 22,047,059 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,092,155 - 22,103,917 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,040,177 - 20,051,939 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1820,040,176 - 20,051,939 (+)NCBI
Celera820,948,090 - 20,959,852 (+)NCBICelera
RH 3.4 Map8206.11RGD
Cytogenetic Map8q13NCBI
ICAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1910,271,093 - 10,286,615 (+)EnsemblGRCh38hg38GRCh38
GRCh381910,271,120 - 10,286,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,381,796 - 10,397,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,242,779 - 10,258,291 (+)NCBINCBI36hg18NCBI36
Build 341910,242,778 - 10,258,291NCBI
Celera1910,276,917 - 10,292,687 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,965,426 - 9,977,270 (+)NCBIHuRef
CHM1_11910,381,783 - 10,397,556 (+)NCBICHM1_1
Icam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,927,236 - 20,940,110 (+)NCBIGRCm39mm39
GRCm39 Ensembl920,927,281 - 20,940,113 (+)Ensembl
GRCm38921,015,940 - 21,028,814 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,015,985 - 21,028,817 (+)EnsemblGRCm38mm10GRCm38
MGSCv37920,820,404 - 20,833,241 (+)NCBIGRCm37mm9NCBIm37
MGSCv36920,766,362 - 20,779,199 (+)NCBImm8
Celera918,284,644 - 18,297,383 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.69NCBI
Icam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,561,714 - 1,574,755 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,561,464 - 1,573,282 (+)NCBIChiLan1.0ChiLan1.0
ICAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11910,484,414 - 10,500,605 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,484,414 - 10,500,605 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0199,821,402 - 9,837,021 (+)NCBIMhudiblu_PPA_v0panPan3
ICAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,818,715 - 50,827,914 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,818,715 - 50,827,914 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,688,470 - 50,697,454 (-)NCBI
ROS_Cfam_1.02051,340,345 - 51,349,327 (-)NCBI
UMICH_Zoey_3.12050,546,484 - 50,555,463 (-)NCBI
UNSW_CanFamBas_1.02050,975,237 - 50,984,210 (-)NCBI
UU_Cfam_GSD_1.02051,216,377 - 51,225,401 (-)NCBI
Icam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,727,534 - 209,738,599 (-)NCBI
SpeTri2.0NW_004936659616,570 - 627,172 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ICAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,097,122 - 69,108,205 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,097,136 - 69,107,722 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,431,462 - 69,442,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ICAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,320,991 - 9,338,125 (+)NCBI
ChlSab1.1 Ensembl69,322,550 - 9,338,263 (+)Ensembl
Vero_WHO_p1.0NW_02366607410,702,922 - 10,719,213 (-)NCBI
Icam1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248282,432,584 - 2,451,997 (+)NCBI

Position Markers
RH94539  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2819,565,254 - 19,565,417 (+)MAPPERmRatBN7.2
Rnor_6.0822,046,877 - 22,047,039NCBIRnor6.0
Rnor_5.0822,103,745 - 22,103,907UniSTSRnor5.0
RGSC_v3.4820,051,767 - 20,051,929UniSTSRGSC3.4
Celera820,959,680 - 20,959,842UniSTS
RH 3.4 Map8206.11UniSTS
Cytogenetic Map8q13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat