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Gene: Icam1 (intercellular adhesion molecule 1) Rattus norvegicus
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Symbol: Icam1
Name: intercellular adhesion molecule 1
Description: Exhibits integrin binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and gonad development. Localizes to the cell surface; extracellular space; and plasma membrane. Predicted to colocalize with the membrane raft. Used to study diabetic angiopathy; mesenteric vascular occlusion; nephritis; pre-eclampsia; and uveitis. Biomarker of several diseases, including cerebrovascular disease (multiple); glucose metabolism disease (multiple); kidney failure (multiple); lung disease (multiple); and retinal disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; Graves' disease; biliary atresia; eye disease (multiple); and inflammatory bowel disease (multiple). Orthologous to human ICAM1 (intercellular adhesion molecule 1); PARTICIPATES IN eicosanoid signaling pathway; influenza A pathway; malaria pathway; INTERACTS WITH (+)-schisandrin B; (+)-Tetrandrine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD54; ICAM; ICAM-1
Orthologs:
Homo sapiens (human) : ICAM1 (intercellular adhesion molecule 1)  HGNC  Alliance
Mus musculus (house mouse) : Icam1 (intercellular adhesion molecule 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icam1 (intercellular adhesion molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ICAM1 (intercellular adhesion molecule 1)
Canis lupus familiaris (dog) : ICAM1 (intercellular adhesion molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icam1 (intercellular adhesion molecule 1)
Sus scrofa (pig) : ICAM1 (intercellular adhesion molecule 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0822,035,287 - 22,047,049 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0822,092,155 - 22,103,917 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,040,177 - 20,051,939 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1820,040,176 - 20,051,939 (+)NCBI
Celera820,948,090 - 20,959,852 (+)NCBICelera
Cytogenetic Map8q13NCBI
RH 3.4 Map8206.11RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)