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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:6469
Term: linalyl acetate
Definition: A racemate comprising equimolar amounts of (R)- and (S)-linalyl acetate. It forms a principal component of the essential oils from bergamot and lavender.
Chemical ID: MESH:C074463
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:107566480464CTDlinalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]

PMID:29276222
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.