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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Icam1decreases expressionEXP 6480464CTDtroglitazone results in decreased expression of ICAM1 mRNAPMID:21515302
Icam1decreases expressionISOICAM1 (Homo sapiens)6480464CTDtroglitazone results in decreased expression of ICAM1 mRNA; troglitazone results in decreased expression of ICAM1 proteinPMID:17425601
Icam1increases expressionISOICAM1 (Homo sapiens)6480464CTDtroglitazone results in increased expression of ICAM1 mRNA; troglitazone results in increased expression of ICAM1 proteinPMID:11401521
Icam1multiple interactionsISOICAM1 (Homo sapiens)6480464CTDPPARG protein affects the reaction [troglitazone results in increased expression of ICAM1 mRNA]PMID:11401521
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