GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Icam1 | increases expression | EXP | | 6480464 | CTD | sodium arsenite results in increased expression of ICAM1 protein | PMID:25058445 | Icam1 | multiple interactions | EXP | | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 protein] | PMID:25058445 PMID:30835071 | Icam1 | decreases expression | ISO | Icam1 (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of ICAM1 mRNA | PMID:25270620 | Icam1 | decreases expression | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of ICAM1 mRNA; sodium arsenite results in decreased expression of ICAM1 protein | PMID:12634122 PMID:9176145 | Icam1 | increases expression | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of ICAM1 mRNA; sodium arsenite results in increased expression of ICAM1 protein | PMID:29301061 PMID:30635848 PMID:36089002 | Icam1 | increases secretion | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased secretion of ICAM1 protein modified form | PMID:28973481 | Icam1 | multiple interactions | ISO | Icam1 (Mus musculus) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of ICAM1 protein; [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of ICAM1 mRNA; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 protein; sodium arsenite promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] | PMID:30635848 PMID:31238026 PMID:33049506 PMID:34876320 | Icam1 | multiple interactions | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | [sodium arsenite co-treated with TNF protein] results in decreased expression of ICAM1 protein; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 mRNA; Enalapril inhibits the reaction [sodium arsenite results in increased secretion of ICAM1 protein modified form]; ERN1 affects the reaction [sodium arsenite results in increased secretion of ICAM1 protein]; HIF1A affects the reaction [sodium arsenite results in increased secretion of ICAM1 protein]; HMOX1 protein affects the reaction [sodium arsenite inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; sodium arsenite inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; sodium arsenite inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; sodium arsenite promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [sodium arsenite results in increased secretion of ICAM1 protein modified form]; XBP1 affects the reaction [sodium arsenite results in increased secretion of ICAM1 protein] | PMID:19371606 PMID:28973481 PMID:30635848 PMID:36669534 PMID:9176145 | | ||||||||||||||||||||||
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