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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Icam1multiple interactionsEXP 6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 protein; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 protein]PMID:30835071
Icam1affects expressionISOICAM1 (Homo sapiens)6480464CTDArsenic affects the expression of ICAM1 mRNAPMID:18414638 PMID:28793237
Icam1increases expressionISOICAM1 (Homo sapiens)6480464CTDArsenic results in increased expression of ICAM1 protein; Arsenic results in increased expression of ICAM1 protein alternative formPMID:17938729 PMID:23761297
Icam1multiple interactionsISOIcam1 (Mus musculus)6480464CTD[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of ICAM1 protein; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 proteinPMID:31238026 PMID:33049506
Icam1multiple interactionsISOICAM1 (Homo sapiens)6480464CTD[Arsenic results in increased expression of and results in increased secretion of MMP9 protein] which results in increased expression of ICAM1 protein; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ICAM1 mRNAPMID:26637202 PMID:36669534
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