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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:134190
Term: capsiate
Definition: A carboxylic ester obtained by formal condensation of the carboxy group of (6E)-8-methylnon-6-enoic acid with the benzylic hydroxy group of vanillyl alcohol. A non-pungent analogue of capsaicin with a similar biological profile.
Chemical ID: MESH:C470213
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases localizationISORGD:696596480464CTDcapsiate analog results in decreased localization of ICAM1 protein

PMID:12115659
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.