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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:107566480464CTDSilicon Dioxide results in increased expression of ICAM1 mRNA, Silicon Dioxide results in increased expression of ICAM1 protein

PMID:23221170, PMID:27428020
increases expressionISORGD:696596480464CTDSilicon Dioxide analog results in increased expression of ICAM1 mRNA, Silicon Dioxide results in increased expression of ICAM1 mRNA

PMID:21540303, PMID:23806026, PMID:25351596, PMID:25895662, PMID:27917503
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.