GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Icam1 | affects expression | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | Zinc affects the expression of ICAM1 mRNA | PMID:16979875 | Icam1 | increases expression | ISO | Icam1 (Mus musculus) | 6480464 | CTD | Zinc deficiency results in increased expression of ICAM1 mRNA | PMID:30635848 | Icam1 | increases expression | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | Zinc deficiency results in increased expression of ICAM1 mRNA; Zinc results in increased expression of ICAM1 mRNA; Zinc results in increased expression of ICAM1 protein | PMID:30635848 PMID:7893746 | Icam1 | multiple interactions | ISO | Icam1 (Mus musculus) | 6480464 | CTD | [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ICAM1 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ICAM1 mRNA] | PMID:23503329 | Icam1 | multiple interactions | ISO | ICAM1 (Homo sapiens) | 6480464 | CTD | Zinc deficiency promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Zinc deficiency promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; Zinc inhibits the reaction [TNF protein results in increased secretion of ICAM1 protein] | PMID:16606632 PMID:30635848 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |