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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:3001
Term: beclomethasone
Definition: A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively.
Chemical ID: MESH:D001507
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:696596480464CTDBeclomethasone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]

PMID:9150321
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.