Gene: Itgal (integrin subunit alpha L) Rattus norvegicus
Symbol: Itgal
Name: integrin subunit alpha L
Description: ENCODES a protein that exhibits protein heterodimerization activity; protein-containing complex binding; cell adhesion molecule binding (ortholog); INVOLVED IN cell-cell adhesion; activated T cell proliferation (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN integrin mediated signaling pathway; malaria pathway; myocarditis pathway; ASSOCIATED WITH nephritis; acute promyelocytic leukemia (ortholog); Behcet's disease (ortholog); FOUND IN cell surface; cell-cell junction (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin alpha L; integrin alpha-L; integrin, alpha L; LFA-1; lymphocyte function-associated antigen-1
Homo sapiens (human) : ITGAL (integrin subunit alpha L)  HGNC  Alliance
Mus musculus (house mouse) : Itgal (integrin alpha L)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgal (integrin subunit alpha L)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGAL (integrin subunit alpha L)
Canis lupus familiaris (dog) : ITGAL (integrin subunit alpha L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgal (integrin subunit alpha L)
Sus scrofa (pig) : ITGAL (integrin subunit alpha L)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01198,744,053 - 198,781,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01205,742,280 - 205,780,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,561,795 - 186,598,908 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,716,379 - 186,726,577 (+)NCBI
Celera1179,569,739 - 179,607,287 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Itgal
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631424
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE