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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:63041
Term: manganese(II) chloride
Definition: An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Chemical ID: MESH:C025340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDmanganese chloride results in decreased expression of ICAM1 protein

PMID:23329836
multiple interactionsISORGD:696596480464CTDmanganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein], manganese chloride inhibits the reaction [Glucose results in increased expression of ICAM1 protein]

PMID:23329836
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.