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Gene: ICAM3 (intercellular adhesion molecule 3) Homo sapiens
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Symbol: ICAM3
Name: intercellular adhesion molecule 3
Description: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD50; CDW50; ICAM-3; ICAM-R; intercellular adhesion molecule-3
Orthologs:
Pan paniscus (bonobo/pygmy chimpanzee) : ICAM3 (intercellular adhesion molecule 3)
Canis lupus familiaris (dog) : ICAM3 (intercellular adhesion molecule 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icam3 (intercellular adhesion molecule 3)
Sus scrofa (pig) : ICAM3 (intercellular adhesion molecule 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,333,776 - 10,339,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,444,452 - 10,450,345 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,305,452 - 10,311,307 (-)NCBINCBI36hg18NCBI36
Build 341910,305,453 - 10,311,300NCBI
Celera1910,339,843 - 10,345,750 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,024,713 - 10,030,606 (-)NCBIHuRef
CHM1_11910,444,986 - 10,451,054 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ICAM3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343048
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.