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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:50594
Term: carbon nanotube
Definition: A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.
Chemical ID: MESH:D037742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:107566480464CTDNanotubes, Carbon analog results in increased expression of ICAM1 mRNA, Nanotubes, Carbon results in increased expression of ICAM1 mRNA

PMID:22293422, PMID:25554681, PMID:25620056
increases expressionISORGD:696596480464CTDNanotubes, Carbon results in increased expression of ICAM1 mRNA

PMID:24389112, PMID:26589480
increases secretionISORGD:696596480464CTDNanotubes, Carbon results in increased secretion of ICAM1 protein

PMID:31047983
multiple interactionsISORGD:696596480464CTD[Nanotubes, Carbon co-treated with calfactant] results in increased expression of ICAM1 mRNA

PMID:23026733
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.