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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:5138
Term: fluvoxamine
Definition: A 5-methoxyvalerophenone O-(2-aminoethyl)oxime that has formula C15H21F3N2O2.
Chemical ID: MESH:D016666
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Icam1multiple interactionsEXP 6480464CTDFluvoxamine inhibits the reaction [Carrageenan results in increased expression of ICAM1 mRNA]

PMID:27803785
Icam1multiple interactionsISORGD:696596480464CTDFluvoxamine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ICAM1 mRNA]

PMID:27803785
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.