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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | polycystic ovary syndrome | | ISO | RGD:68446 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21411543 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | polycystic ovary syndrome | | ISO | RGD:68446 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21411543 | |
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# | Reference Title | Reference Citation |
1. | Rho proteins are localized with different membrane compartments involved in vesicular trafficking in anterior pituitary cells. | Cussac D, etal., Mol Cell Endocrinol. 1996 May 31;119(2):195-206. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rab proteins in endocytosis and Glut4 trafficking. | Kaddai V, etal., Acta Physiol (Oxf). 2008 Jan;192(1):75-88. |
4. | Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. | Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15. |
5. | The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons. | Krijnse-Locker J, etal., Mol Biol Cell. 1995 Oct;6(10):1315-32. |
6. | The GLUT4 code. | Larance M, etal., Mol Endocrinol. 2008 Feb;22(2):226-33. Epub 2007 Aug 23. |
7. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
8. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
9. | Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. | Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010. |
10. | GOA pipeline | RGD automated data pipeline |
11. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
12. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
13. | Tentative Sequence Identification Numbers | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
14. | Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation. | Tisdale EJ J Biol Chem 2003 Dec 26;278(52):52524-30. Epub 2003 Oct 21. |
15. | The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. | Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May. |
16. | Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library. | Touchot N, etal., Proc Natl Acad Sci U S A 1987 Dec;84(23):8210-4. |
17. | GLUT4 translocation: the last 200 nanometers. | Watson RT and Pessin JE, Cell Signal. 2007 Nov;19(11):2209-17. Epub 2007 Jun 21. |
18. | Insulin action on glucose transporters through molecular switches, tracks and tethers. | Zaid H, etal., Biochem J. 2008 Jul 15;413(2):201-15. |
PMID:11042173 | PMID:16034420 | PMID:17488287 | PMID:17562788 | PMID:17684057 | PMID:17897319 | PMID:19056867 | PMID:20458337 | PMID:21630459 | PMID:21700703 | PMID:23376485 | PMID:23533145 |
PMID:24625528 | PMID:29476059 |
Rab2a (Rattus norvegicus - Norway rat) |
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RAB2A (Homo sapiens - human) |
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Rab2a (Mus musculus - house mouse) |
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Rab2a (Chinchilla lanigera - long-tailed chinchilla) |
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RAB2A (Pan paniscus - bonobo/pygmy chimpanzee) |
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RAB2A (Canis lupus familiaris - dog) |
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Rab2a (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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RAB2A (Sus scrofa - pig) |
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RAB2A (Chlorocebus sabaeus - green monkey) |
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Rab2a (Heterocephalus glaber - naked mole-rat) |
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Variants in Rab2a
231 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
AW535887 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | |||||||||||||
Below cutoff |
RefSeq Transcripts | NM_031718 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_017593615 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473984 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
FQ228812 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ229541 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
J02999 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000160 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000008522 ⟹ ENSRNOP00000008522 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000112446 ⟹ ENSRNOP00000088413 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_031718 ⟹ NP_113906 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_113906 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | AAA42007 | (Get FASTA) | NCBI Sequence Viewer |
EDM11646 | (Get FASTA) | NCBI Sequence Viewer | |
P05712 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_113906 ⟸ NM_031718 |
- UniProtKB: | A0A8I6A522 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000008522 ⟸ ENSRNOT00000008522 |
RefSeq Acc Id: | ENSRNOP00000088413 ⟸ ENSRNOT00000112446 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-P05712-F1-model_v2 | AlphaFold | P05712 | 1-212 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:68323 | AgrOrtholog |
BioCyc Gene | G2FUF-42055 | BioCyc |
Ensembl Genes | ENSRNOG00000005963 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000008522.6 | UniProtKB/TrEMBL |
ENSRNOP00000088413 | ENTREZGENE | |
ENSRNOP00000088413.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000008522.6 | UniProtKB/TrEMBL |
ENSRNOT00000112446 | ENTREZGENE | |
ENSRNOT00000112446.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.40.50.300 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Small_GTP-bd_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Small_GTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:65158 | UniProtKB/Swiss-Prot |
NCBI Gene | 65158 | ENTREZGENE |
PANTHER | DRAB11-RELATED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RAS-RELATED PROTEIN RAB-2A | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Ras | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Rab2a | PhenoGen |
PRINTS | RASTRNSFRMNG | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | RAB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RAS | UniProtKB/TrEMBL | |
RHO | UniProtKB/TrEMBL | |
SMART | RAB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RAN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RAS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RHO | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TIGR | TC217442 | |
TIGRFAMs | small_GTP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A8I6A522 | ENTREZGENE, UniProtKB/TrEMBL |
F1LP82_RAT | UniProtKB/TrEMBL | |
P05712 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-04-25 | Rab2a | RAB2A, member RAS oncogene family | Rab2 | RAB2, member RAS oncogene family | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2002-06-10 | Rab2 | RAB2, member RAS oncogene family | Name updated | 70584 | APPROVED |
Note Type | Note | Reference |
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