Rab2a (RAB2A, member RAS oncogene family) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rab2a (RAB2A, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab2a
Name: RAB2A, member RAS oncogene family
RGD ID: 68323
Description: Enables GTP binding activity. Predicted to be involved in Golgi organization; macroautophagy; and vesicle-mediated transport. Located in several cellular components, including Golgi membrane; neuronal cell body; and perinuclear region of cytoplasm. Is active in synaptic vesicle membrane. Orthologous to human RAB2A (RAB2A, member RAS oncogene family); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Rab2; RAB2, member RAS oncogene family; ras-related protein Rab-2A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8526,473,424 - 26,537,441 (+)NCBIGRCr8
mRatBN7.2521,676,017 - 21,740,035 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl521,676,129 - 21,739,899 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx523,908,990 - 23,971,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0525,496,252 - 25,558,865 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0525,276,527 - 25,339,148 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0521,632,654 - 21,696,721 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl521,632,926 - 21,695,519 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0526,385,934 - 26,449,989 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4522,389,585 - 22,452,198 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1522,389,584 - 22,452,198 (+)NCBI
Celera520,943,721 - 21,006,339 (+)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-bromohexadecanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetylsalicylic acid  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichlorine  (EXP)
elemental selenium  (ISO)
Enterolactone  (ISO)
ethanol  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen cyanide  (ISO)
hydroxytyrosol  (ISO)
ivermectin  (ISO)
mercury dichloride  (ISO)
Mesaconitine  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nicotine  (ISO)
nimesulide  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP)
paraquat  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium cyanide  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
thapsigargin  (EXP)
thiram  (ISO)
tipifarnib  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function
G protein activity  (ISO,ISS)
GDP binding  (IEA,ISO,ISS)
GTP binding  (IBA,IDA,IEA,ISO,ISS)
GTPase activity  (IBA,IEA,ISO,ISS)
hydrolase activity  (IEA)
nucleotide binding  (IEA)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Rho proteins are localized with different membrane compartments involved in vesicular trafficking in anterior pituitary cells. Cussac D, etal., Mol Cell Endocrinol. 1996 May 31;119(2):195-206.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rab proteins in endocytosis and Glut4 trafficking. Kaddai V, etal., Acta Physiol (Oxf). 2008 Jan;192(1):75-88.
4. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5. The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons. Krijnse-Locker J, etal., Mol Biol Cell. 1995 Oct;6(10):1315-32.
6. The GLUT4 code. Larance M, etal., Mol Endocrinol. 2008 Feb;22(2):226-33. Epub 2007 Aug 23.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14. Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation. Tisdale EJ J Biol Chem 2003 Dec 26;278(52):52524-30. Epub 2003 Oct 21.
15. The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May.
16. Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library. Touchot N, etal., Proc Natl Acad Sci U S A 1987 Dec;84(23):8210-4.
17. GLUT4 translocation: the last 200 nanometers. Watson RT and Pessin JE, Cell Signal. 2007 Nov;19(11):2209-17. Epub 2007 Jun 21.
18. Insulin action on glucose transporters through molecular switches, tracks and tethers. Zaid H, etal., Biochem J. 2008 Jul 15;413(2):201-15.
Additional References at PubMed
PMID:11042173   PMID:16034420   PMID:17488287   PMID:17562788   PMID:17684057   PMID:17897319   PMID:19056867   PMID:20458337   PMID:21630459   PMID:21700703   PMID:23376485   PMID:23533145  
PMID:24625528   PMID:29476059  


Genomics

Comparative Map Data
Rab2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8526,473,424 - 26,537,441 (+)NCBIGRCr8
mRatBN7.2521,676,017 - 21,740,035 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl521,676,129 - 21,739,899 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx523,908,990 - 23,971,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0525,496,252 - 25,558,865 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0525,276,527 - 25,339,148 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0521,632,654 - 21,696,721 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl521,632,926 - 21,695,519 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0526,385,934 - 26,449,989 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4522,389,585 - 22,452,198 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1522,389,584 - 22,452,198 (+)NCBI
Celera520,943,721 - 21,006,339 (+)NCBICelera
Cytogenetic Map5q13NCBI
RAB2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38860,516,910 - 60,623,644 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl860,516,936 - 60,623,644 (+)EnsemblGRCh38hg38GRCh38
GRCh37861,429,469 - 61,536,203 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36861,592,113 - 61,696,183 (+)NCBINCBI36Build 36hg18NCBI36
Build 34861,592,112 - 61,696,183NCBI
Celera857,418,606 - 57,523,216 (+)NCBICelera
Cytogenetic Map8q12.1-q12.2NCBI
HuRef856,917,062 - 57,023,312 (+)NCBIHuRef
CHM1_1861,481,468 - 61,587,847 (+)NCBICHM1_1
T2T-CHM13v2.0860,940,688 - 61,047,387 (+)NCBIT2T-CHM13v2.0
Rab2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,535,661 - 8,607,708 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl48,535,644 - 8,607,778 (+)EnsemblGRCm39 Ensembl
GRCm3848,535,469 - 8,607,702 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,535,644 - 8,607,778 (+)EnsemblGRCm38mm10GRCm38
MGSCv3748,462,791 - 8,534,849 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3648,462,791 - 8,534,849 (+)NCBIMGSCv36mm8
Celera48,374,576 - 8,447,455 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.63NCBI
Rab2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544418,091,640 - 18,169,971 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544418,091,640 - 18,169,971 (-)NCBIChiLan1.0ChiLan1.0
RAB2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2776,173,305 - 76,270,717 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1851,827,243 - 51,929,882 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0856,931,782 - 57,034,343 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1858,630,403 - 58,698,710 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl858,633,850 - 58,698,710 (+)Ensemblpanpan1.1panPan2
RAB2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12910,953,425 - 11,042,789 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2910,953,371 - 11,041,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2911,265,380 - 11,353,510 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02911,046,164 - 11,135,843 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2911,045,930 - 11,136,239 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12911,039,366 - 11,127,487 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02911,176,985 - 11,265,106 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02911,444,643 - 11,532,770 (+)NCBIUU_Cfam_GSD_1.0
Rab2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530362,105,130 - 62,159,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649612,626,250 - 12,680,365 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649612,626,242 - 12,680,334 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl472,800,623 - 72,882,151 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1472,800,617 - 72,882,183 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2479,257,583 - 79,342,260 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1856,439,021 - 56,542,059 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl856,438,780 - 56,540,827 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603985,133,880 - 85,238,208 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474431,357,925 - 31,441,371 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474431,357,926 - 31,441,341 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rab2a
255 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:151
Count of miRNA genes:128
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000008522
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5213896532656739Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5384401826141981Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat

Markers in Region
AW535887  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2521,703,952 - 21,704,112 (+)MAPPERmRatBN7.2
Rnor_6.0521,660,642 - 21,660,801NCBIRnor6.0
Rnor_5.0526,413,910 - 26,414,069UniSTSRnor5.0
RGSC_v3.4522,417,319 - 22,417,478UniSTSRGSC3.4
Celera520,971,455 - 20,971,614UniSTS
RH 3.4 Map5115.8UniSTS
Cytogenetic Map5q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000008522   ⟹   ENSRNOP00000008522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl521,695,810 - 21,736,933 (+)Ensembl
Rnor_6.0 Ensembl521,632,926 - 21,695,519 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112446   ⟹   ENSRNOP00000088413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl521,676,129 - 21,739,899 (+)Ensembl
RefSeq Acc Id: NM_031718   ⟹   NP_113906
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8526,473,424 - 26,537,441 (+)NCBI
mRatBN7.2521,676,017 - 21,740,035 (+)NCBI
Rnor_6.0521,632,909 - 21,695,519 (+)NCBI
Rnor_5.0526,385,934 - 26,449,989 (+)NCBI
RGSC_v3.4522,389,585 - 22,452,198 (+)RGD
Celera520,943,721 - 21,006,339 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113906 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42007 (Get FASTA)   NCBI Sequence Viewer  
  EDM11646 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008522.6
  ENSRNOP00000088413
  ENSRNOP00000088413.1
GenBank Protein P05712 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113906   ⟸   NM_031718
- UniProtKB: P05712 (UniProtKB/Swiss-Prot),   A0A8I6A522 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008522   ⟸   ENSRNOT00000008522
Ensembl Acc Id: ENSRNOP00000088413   ⟸   ENSRNOT00000112446

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05712-F1-model_v2 AlphaFold P05712 1-212 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68323 AgrOrtholog
BioCyc Gene G2FUF-42055 BioCyc
Ensembl Genes ENSRNOG00000005963 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008522.6 UniProtKB/TrEMBL
  ENSRNOT00000112446 ENTREZGENE
  ENSRNOT00000112446.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab_GTPases_membrane_traffic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65158 UniProtKB/Swiss-Prot
NCBI Gene 65158 ENTREZGENE
PANTHER DRAB11-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rab2a PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005963 RatGTEx
SMART RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217442
UniProt A0A8I6A522 ENTREZGENE, UniProtKB/TrEMBL
  F1LP82_RAT UniProtKB/TrEMBL
  P05712 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-25 Rab2a  RAB2A, member RAS oncogene family  Rab2  RAB2, member RAS oncogene family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Rab2  RAB2, member RAS oncogene family      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference