Ip6k2 (inositol hexakisphosphate kinase 2)

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Gene: Ip6k2 (inositol hexakisphosphate kinase 2) Rattus norvegicus

Analyze

Symbol:

Ip6k2

Name:

inositol hexakisphosphate kinase 2

RGD ID:

620529

Description:

Predicted to enable flavonoid binding activity and inositol hexakisphosphate 5-kinase activity. Involved in phosphate ion transport. Predicted to be located in cell junction; fibrillar center; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human IP6K2 (inositol hexakisphosphate kinase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Ihpk2; inositol hexaphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; Pius

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IP6K2 (inositol hexakisphosphate kinase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Ip6k2 (inositol hexaphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ip6k2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IP6K2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IP6K2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ip6k2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IP6K2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IP6K2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ip6k2 (inositol hexakisphosphate kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	IP6K2 (inositol hexakisphosphate kinase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ip6k2 (inositol hexaphosphate kinase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ip6k2a (inositol hexakisphosphate kinase 2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ip6k2b (inositol hexakisphosphate kinase 2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10082	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F30A10.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	KCS1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ARG82	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	109,483,843 - 109,510,172 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	109,484,310 - 109,510,166 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	115,103,519 - 115,127,769 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	8	113,302,698 - 113,326,948 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	8	111,145,495 - 111,169,746 (+)	NCBI	Rnor_WKY
Rnor_6.0	8	117,574,136 - 117,599,849 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,574,161 - 117,599,848 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	116,921,132 - 116,944,750 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	113,836,756 - 113,861,895 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	113,870,909 - 113,881,351 (+)	NCBI
Celera	8	108,780,684 - 108,804,293 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 1 (ISO)

Huntington's disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

ciguatoxin CTX1B (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (ISO)

endosulfan (EXP)

Enterolactone (ISO)

erythromycin estolate (EXP)

estriol (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

folic acid (ISO)

formaldehyde (ISO)

gallic acid (ISO)

iron atom (ISO)

iron(0) (ISO)

leflunomide (EXP)

levofloxacin (EXP)

methidathion (ISO)

methyl methanesulfonate (ISO)

Methylazoxymethanol acetate (EXP)

N-nitrosodiethylamine (EXP)

orphenadrine (EXP)

oxycodone (EXP)

paracetamol (EXP,ISO)

phenethyl caffeate (EXP)

phenformin (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

quercetin (ISO)

ritodrine (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

Soman (EXP)

tetrachloromethane (EXP,ISO)

triptonide (ISO)

troglitazone (ISO)

trovafloxacin (EXP)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to flavonoid (ISO,ISS)

inositol phosphate biosynthetic process (IBA,IEA,ISO)

inositol phosphate metabolic process (ISO,ISS)

negative regulation of cell growth (ISO)

phosphate ion transport (IDA)

phosphatidylinositol phosphate biosynthetic process (IBA,ISO)

phosphorylation (IEA)

positive regulation of apoptotic process (ISO)

positive regulation of peptidyl-serine phosphorylation (ISO)

protein stabilization (ISO)

Cellular Component

cell junction (IEA,ISO)

cytoplasm (IBA)

fibrillar center (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

Molecular Function

ATP binding (IEA)

flavonoid binding (ISO,ISS)

inositol hexakisphosphate 5-kinase activity (ISO,ISS)

inositol hexakisphosphate kinase activity (IBA,ISO)

kinase activity (IBA,IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Regulation of intestinal Na+-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3.	Katai K, etal., Biochem J 1999 Nov 1;343 Pt 3:705-12.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10574768	PMID:11337497	PMID:11502751	PMID:12477932	PMID:30624931

Genomics

Comparative Map Data

Ip6k2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	109,483,843 - 109,510,172 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	109,484,310 - 109,510,166 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	115,103,519 - 115,127,769 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	8	113,302,698 - 113,326,948 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	8	111,145,495 - 111,169,746 (+)	NCBI	Rnor_WKY
Rnor_6.0	8	117,574,136 - 117,599,849 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,574,161 - 117,599,848 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	116,921,132 - 116,944,750 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	113,836,756 - 113,861,895 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	113,870,909 - 113,881,351 (+)	NCBI
Celera	8	108,780,684 - 108,804,293 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

IP6K2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	48,688,003 - 48,717,221 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	3	48,688,003 - 48,740,353 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	48,725,436 - 48,754,654 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	48,700,440 - 48,729,710 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	48,700,440 - 48,729,710	NCBI
Celera	3	48,681,373 - 48,710,646 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	48,783,857 - 48,813,325 (-)	NCBI		HuRef
CHM1_1	3	48,677,527 - 48,706,810 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	48,716,988 - 48,746,201 (-)	NCBI		T2T-CHM13v2.0

Ip6k2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	108,660,928 - 108,683,532 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	108,660,995 - 108,683,536 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	108,783,764 - 108,806,333 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	108,783,796 - 108,806,337 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	108,698,325 - 108,708,664 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	108,653,217 - 108,663,556 (+)	NCBI		MGSCv36	mm8
Celera	9	108,403,128 - 108,413,468 (+)	NCBI		Celera
Cytogenetic Map	9	F2	NCBI

Ip6k2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	766,577 - 794,409 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	766,577 - 794,461 (-)	NCBI	ChiLan1.0	ChiLan1.0

IP6K2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	49,690,486 - 49,719,811 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	49,690,486 - 49,719,798 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	48,608,902 - 48,638,185 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

IP6K2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	40,403,260 - 40,437,863 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	40,427,083 - 40,437,804 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	40,320,579 - 40,355,092 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	40,888,751 - 40,923,377 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	40,888,832 - 40,923,377 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	40,126,293 - 40,160,881 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	40,530,369 - 40,565,188 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	40,812,078 - 40,846,684 (+)	NCBI		UU_Cfam_GSD_1.0

Ip6k2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	63,726,780 - 63,755,149 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	486,879 - 515,674 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936529	487,277 - 515,614 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IP6K2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	31,379,521 - 31,406,911 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	31,379,516 - 31,406,989 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	34,646,759 - 34,655,148 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IP6K2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	10,097,730 - 10,121,325 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	10,097,746 - 10,121,840 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	156,967,477 - 156,992,136 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ip6k2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	2,697,098 - 2,734,636 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	2,697,098 - 2,734,198 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ip6k2
82 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	47
Interacting mature miRNAs:	56
Transcripts:	ENSRNOT00000027584
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	46531639	119088624	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	8	46531639	119088624	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	8	46531639	119088624	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088624	Rat
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
631653	Bp125	Blood pressure QTL 125	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	66142385	111142385	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	69349194	112783834	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	70513503	118219066	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	71888757	116888757	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	71888757	116888757	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	71888757	116888757	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	71888757	116888757	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	73473045	118473045	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	89265192	114019816	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat

Markers in Region

RH144690

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	109,497,031 - 109,497,247 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,586,900 - 117,587,115	NCBI	Rnor6.0
Rnor_5.0	8	116,932,067 - 116,932,282	UniSTS	Rnor5.0
RGSC_v3.4	8	113,848,833 - 113,849,048	UniSTS	RGSC3.4
Celera	8	108,791,530 - 108,791,745	UniSTS
RH 3.4 Map	8	1115.3	UniSTS
Cytogenetic Map	8	q32	UniSTS

UniSTS:532317

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	109,509,564 - 109,509,986 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,599,243 - 117,599,664	NCBI	Rnor6.0
Rnor_5.0	8	116,944,144 - 116,944,565	UniSTS	Rnor5.0
Celera	8	108,803,687 - 108,804,108	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	57	41	19	41	1	1	74	35	41	11	1
Low		7					7	10					7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000027584 ⟹ ENSRNOP00000027584

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	109,499,531 - 109,510,166 (+)	Ensembl
Rnor_6.0 Ensembl	8	117,576,788 - 117,599,848 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000077078 ⟹ ENSRNOP00000071056

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	109,484,310 - 109,510,166 (+)	Ensembl
Rnor_6.0 Ensembl	8	117,574,161 - 117,599,843 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099109 ⟹ ENSRNOP00000092455

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	109,499,531 - 109,500,567 (+)	Ensembl

RefSeq Acc Id:

NM_021660 ⟹ NP_067692

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	109,486,179 - 109,510,172 (+)	NCBI
Rnor_6.0	8	117,576,048 - 117,599,849 (+)	NCBI
Rnor_5.0	8	116,921,132 - 116,944,750 (+)	NCBI
RGSC_v3.4	8	113,836,756 - 113,861,895 (+)	RGD
Celera	8	108,780,684 - 108,804,293 (+)	RGD

Sequence:

show sequence

CCTGCCTCTGATGTGCCAGGATTAGAGAGTGCTGAAGACAAGAAGTTTTGGAGTTGTGAGTGAA
TCCCGGTACTCAAAAATGAGGCTACTTCCAAACCTCATGTCATTGTGTTTGCTTCCGCCAGTGT
GTGCTGGCCTGCACAGACCGAGGAGCAGAGATCAAACAGGCGGCTGTAAGGACAGACAGTAAAC
GGAGGACGAGCTGGCCTCTGGATCCCGCTGCCTCCCCTTTCTCCCTGCTGCCTGTGTCCGGAGG
ATGAGCCCAGCCTTCAGGACCATGGACGTAGAGCCCCGTACCAAGGGCATCCTGCTGGAGCCCT
TTGTCCACCAGGTTGGGGGGCACTCATGCGTTCTCCGGTTCAATGAGACAACCCTGTGCAAGCC
CCTGGTTCCGAGGGAGCATCAGTTCTACGAGACCCTCCCAGCTGAGATGCGCAGATTCACTCCC
CAGTACAAAGGTGTGGTATCAGTACGCTTTGAAGAAGATGAAGACAGGAACTTGTGTTTAATAG
CATATCCATTAAAGGGGGACCATGGACCTGTGGATATTGTAGACAATTCAGACTGTGAACCAAA
AAGTAAGCTGCTGAGATGGACAAACAAAAAACATCACGTCCTAGAAACAGAAAAGAGTCCCAAG
GACTGGGTGCGCCAGCACCGAAAAGAGGAGAAGATGAAGAGCCATAAGTTAGAAGAAGAATTTG
AGTGGCTAAAGAAGTCTGAAGTCTTATACTACAGTGTAGAAAAAAAGGGAACTGTAAGCTCCCA
GCTCAAACACTACAACCCTTGGAGCATGAAGTGTCATCAGCAGCAGCTACAGAGGATGAAGGAG
AACGCGAAGCACCGGAACCAGTACAAATTCATCTTGCTGGAGAACCTGACTTGCCGCTATGAGG
TGCCTTGTGTCCTGGACCTCAAGATGGGCACACGCCAGCATGGCGACGATGCTTCAGAGGAAAA
AGCAGCTAACCAGATCCGAAAATGTCAGCAGAGCACATCTGCAGTCATTGGCGTTCGAGTGTGT
GGCATGCAGGTGTACCAGGCAGGCACTGGGCAGCTCATGTTCATGAACAAGTACCATGGACGGA
AGCTTTCAGTGCAGGGCTTCAAGGAGGCGCTTTTCCAGTTCTTTCACAATGGGCGGTACCTGCG
CCGTGAGCTCCTGGGCCCTGTGCTCAAGAAGCTAACTGAGCTTAAGGCCGTGTTGGAGCGACAG
GAATCCTACCGCTTCTATTCAAGTTCCCTACTGGTCATTTATGATGGCAAGGAATGGCCAGAGG
TGACCCTGGACTCAGATGCTGAGGACTTGGAGGACCTCTCAGAAGAGTCGGCTGATGAGTCTGC
TGGTGCCTATGCCTACAAGCCTCTCGGTGCCAGCTCAGTGGACGTGCGCATGATCGACTTTGCA
CACACCACCTGCAGGCTCTATGGCGAGGACAGTGTGGTGCATGAGGGCCAGGATGCTGGCTATA
TCTTTGGGCTGCAGAGCCTGATAGACATTGTCACAGAGATAAGTGAGGAGAGTGGGGAGTGAGC
TTGCTGGCTAGTCCAGTACCTGAGAGACGCTTTGTGTCCCCCTACAGCTGTGCTGTCGGGAAGC
AGGCCAGTATGGCTAGGTGTTGGCCTCTGCAGCCTGGAGCTGATAGACAGTGGCCCCTGTAACC
CCCCCCCCCCCAGCCTGAGCCAGCCCCAGATGGCTCAGAGCCTTTTATTTATTTTAACTATTTC
TTCAACATTCCACATTTGATGATGCAGATACCTCTTTCTTCCCTGAGTGTAAATGTTCTAATAC
AGATCTTTTTGTTTATTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008766564 ⟹ XP_008764786

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	109,484,212 - 109,510,172 (+)	NCBI
Rnor_6.0	8	117,574,137 - 117,599,849 (+)	NCBI

Sequence:

show sequence

CGGGAGCGAGGCTGGGGGGCGGGGCCGAGCCCGGCCGCAGCCATTTTGGTGGAAGAGAAACAAT
AGGACGGAAGCGTCGCGGGACTGGGCTGTGGCCGCAGTGTGTGCTGGCCTGCACAGACCGAGGA
GCAGAGATCAAACAGGCGGCTGTAAGGACAGACAGTAAACGGAGGACGAGCTGGCCTCTGGATC
CCGCTGCCTCCCCTTTCTCCCTGCTGCCTGTGTCCGGAGGATGAGCCCAGCCTTCAGGACCATG
GACGTAGAGCCCCGTACCAAGGGCATCCTGCTGGAGCCCTTTGTCCACCAGGTTGGGGGGCACT
CATGCGTTCTCCGGTTCAATGAGACAACCCTGTGCAAGCCCCTGGTTCCGAGGGAGCATCAGTT
CTACGAGACCCTCCCAGCTGAGATGCGCAGATTCACTCCCCAGTACAAAGGTGTGGTATCAGTA
CGCTTTGAAGAAGATGAAGACAGGAACTTGTGTTTAATAGCATATCCATTAAAGGGGGACCATG
GACCTGTGGATATTGTAGACAATTCAGACTGTGAACCAAAAAGTAAGCTGCTGAGATGGACAAA
CAAAAAACATCACGTCCTAGAAACAGAAAAGAGTCCCAAGGACTGGGTGCGCCAGCACCGAAAA
GAGGAGAAGATGAAGAGCCATAAGTTAGAAGAAGAATTTGAGTGGCTAAAGAAGTCTGAAGTCT
TATACTACAGTGTAGAAAAAAAGGGAACTGTAAGCTCCCAGCTCAAACACTACAACCCTTGGAG
CATGAAGTGTCATCAGCAGCAGCTACAGAGGATGAAGGAGAACGCGAAGCACCGGAACCAGTAC
AAATTCATCTTGCTGGAGAACCTGACTTGCCGCTATGAGGTGCCTTGTGTCCTGGACCTCAAGA
TGGGCACACGCCAGCATGGCGACGATGCTTCAGAGGAAAAAGCAGCTAACCAGATCCGAAAATG
TCAGCAGAGCACATCTGCAGTCATTGGCGTTCGAGTGTGTGGCATGCAGGTGTACCAGGCAGGC
ACTGGGCAGCTCATGTTCATGAACAAGTACCATGGACGGAAGCTTTCAGTGCAGGGCTTCAAGG
AGGCGCTTTTCCAGTTCTTTCACAATGGGCGGTACCTGCGCCGTGAGCTCCTGGGCCCTGTGCT
CAAGAAGCTAACTGAGCTTAAGGCCGTGTTGGAGCGACAGGAATCCTACCGCTTCTATTCAAGT
TCCCTACTGGTCATTTATGATGGCAAGGAATGGCCAGAGGTGACCCTGGACTCAGATGCTGAGG
ACTTGGAGGACCTCTCAGAAGAGTCGGCTGATGAGTCTGCTGGTGCCTATGCCTACAAGCCTCT
CGGTGCCAGCTCAGTGGACGTGCGCATGATCGACTTTGCACACACCACCTGCAGGCTCTATGGC
GAGGACAGTGTGGTGCATGAGGGCCAGGATGCTGGCTATATCTTTGGGCTGCAGAGCCTGATAG
ACATTGTCACAGAGATAAGTGAGGAGAGTGGGGAGTGAGCTTGCTGGCTAGTCCAGTACCTGAG
AGACGCTTTGTGTCCCCCTACAGCTGTGCTGTCGGGAAGCAGGCCAGTATGGCTAGGTGTTGGC
CTCTGCAGCCTGGAGCTGATAGACAGTGGCCCCTGTAACCCCCCCCCCCCCAGCCTGAGCCAGC
CCCAGATGGCTCAGAGCCTTTTATTTATTTTAACTATTTCTTCAACATTCCACATTTGATGATG
CAGATACCTCTTTCTTCCCTGAGTGTAAATGTTCTAATACAGATCTTTTTGTTTATTGTA

hide sequence

RefSeq Acc Id:

XM_008766566 ⟹ XP_008764788

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	109,484,231 - 109,510,172 (+)	NCBI
Rnor_6.0	8	117,574,136 - 117,599,849 (+)	NCBI

Sequence:

show sequence

CCGGGAGCGAGGCTGGGGGGCGGGGCCGAGCCCGGCCGCAGCCATTTTGGTGGAAGAGAAACAA
TAGGACGGAAGCGTCGCGGGACTGGGCTGTGGCCGCAGTGTGTGCTGGCCTGCACAGACCGAGG
AGCAGAGATCAAACAGGCGGCTGTAAGGACAGACAGTAAACGGAGGACGAGCTGGCCTCTGGAT
CCCGCTGCCTCCCCTTTCTCCCTGCTGCCTGTGTCCGGAGGATGAGCCCAGCCTTCAGGACCAT
GGACGTAGAGCCCCGTACCAAGGGCATCCTGCTGGAGCCCTTTGTCCACCAGGTTGGGGGGCAC
TCATGCGTTCTCCGGTTCAATGAGACAACCCTGTGCAAGCCCCTGGTTCCGAGGGAGCATCAGT
TCTACGAGACCCTCCCAGCTGAGATGCGCAGATTCACTCCCCAGTACAAAGCTGTTTTGATATT
TGTTAGGTTTGCAGATGAGTTTGGGGCCTCTGGCAACATAGAGACTAAGGAACAGGGTGTGGTA
TCAGTACGCTTTGAAGAAGATGAAGACAGGAACTTGTGTTTAATAGCATATCCATTAAAGGGGG
ACCATGGACCTGTGGATATTGTAGACAATTCAGACTGTGAACCAAAAAGTAAGCTGCTGAGATG
GACAAACAAAAAACATCACGTCCTAGAAACAGAAAAGAGTCCCAAGGACTGGGTGCGCCAGCAC
CGAAAAGAGGAGAAGATGAAGAGCCATAAGTTAGAAGAAGAATTTGAGTGGCTAAAGAAGTCTG
AAGTCTTATACTACAGTGTAGAAAAAAAGGGAACTGTAAGCTCCCAGCTCAAACACTACAACCC
TTGGAGCATGAAGTGTCATCAGCAGCAGCTACAGAGGATGAAGGAGAACGCGAAGCACCGGAAC
CAGTACAAATTCATCTTGCTGGAGAACCTGACTTGCCGCTATGAGGTGCCTTGTGTCCTGGACC
TCAAGATGGGCACACGCCAGCATGGCGACGATGCTTCAGAGGAAAAAGCAGCTAACCAGATCCG
AAAATGTCAGCAGAGCACATCTGCAGTCATTGGCGTTCGAGTGTGTGGCATGCAGGTGTACCAG
GCAGGCACTGGGCAGCTCATGTTCATGAACAAGTACCATGGACGGAAGCTTTCAGTGCAGGGCT
TCAAGGAGGCGCTTTTCCAGTTCTTTCACAATGGGCGGTACCTGCGCCGTGAGCTCCTGGGCCC
TGTGCTCAAGAAGCTAACTGAGCTTAAGGCCGTGTTGGAGCGACAGGAATCCTACCGCTTCTAT
TCAAGTTCCCTACTGGTCATTTATGATGGCAAGGAATGGCCAGAGGTGACCCTGGACTCAGATG
CTGAGGACTTGGAGGACCTCTCAGAAGAGTCGGCTGATGAGTCTGCTGGTGCCTATGCCTACAA
GCCTCTCGGTGCCAGCTCAGTGGACGTGCGCATGATCGACTTTGCACACACCACCTGCAGGCTC
TATGGCGAGGACAGTGTGGTGCATGAGGGCCAGGATGCTGGCTATATCTTTGGGCTGCAGAGCC
TGATAGACATTGTCACAGAGATAAGTGAGGAGAGTGGGGAGTGAGCTTGCTGGCTAGTCCAGTA
CCTGAGAGACGCTTTGTGTCCCCCTACAGCTGTGCTGTCGGGAAGCAGGCCAGTATGGCTAGGT
GTTGGCCTCTGCAGCCTGGAGCTGATAGACAGTGGCCCCTGTAACCCCCCCCCCCCCAGCCTGA
GCCAGCCCCAGATGGCTCAGAGCCTTTTATTTATTTTAACTATTTCTTCAACATTCCACATTTG
ATGATGCAGATACCTCTTTCTTCCCTGAGTGTAAATGTTCTAATACAGATCTTTTTGTTTATTG
TA

hide sequence

RefSeq Acc Id:

XM_039082043 ⟹ XP_038937971

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	109,486,926 - 109,510,172 (+)	NCBI

RefSeq Acc Id:

XM_039082044 ⟹ XP_038937972

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	109,483,843 - 109,501,302 (+)	NCBI

RefSeq Acc Id:

XM_039082045 ⟹ XP_038937973

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	109,483,847 - 109,501,302 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_067692	(Get FASTA)	NCBI Sequence Viewer
	XP_008764786	(Get FASTA)	NCBI Sequence Viewer
	XP_008764788	(Get FASTA)	NCBI Sequence Viewer
	XP_038937971	(Get FASTA)	NCBI Sequence Viewer
	XP_038937972	(Get FASTA)	NCBI Sequence Viewer
	XP_038937973	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83574	(Get FASTA)	NCBI Sequence Viewer
	EDL77139	(Get FASTA)	NCBI Sequence Viewer
	EDL77140	(Get FASTA)	NCBI Sequence Viewer
	EDL77141	(Get FASTA)	NCBI Sequence Viewer
	EDL77142	(Get FASTA)	NCBI Sequence Viewer
	EDL77143	(Get FASTA)	NCBI Sequence Viewer
	EDL77144	(Get FASTA)	NCBI Sequence Viewer
	EDL77145	(Get FASTA)	NCBI Sequence Viewer
	Q9R0U1	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_067692 ⟸ NM_021660

- UniProtKB:

Q5XIU6 (UniProtKB/Swiss-Prot), Q9R0U1 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTP
QYKGVVSVRFEEDEDRNLCLIAYPLKGDHGPVDIVDNSDCEPKSKLLRWTNKKHHVLETEKSPK
DWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVEKKGTVSSQLKHYNPWSMKCHQQQLQRMKE
NAKHRNQYKFILLENLTCRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVC
GMQVYQAGTGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQ
ESYRFYSSSLLVIYDGKEWPEVTLDSDAEDLEDLSEESADESAGAYAYKPLGASSVDVRMIDFA
HTTCRLYGEDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE

hide sequence

RefSeq Acc Id:	XP_008764788 ⟸ XM_008766566
- Peptide Label:	isoform X4
- UniProtKB:	A0A8L2UKG6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTP QYKAVLIFVRFADEFGASGNIETKEQGVVSVRFEEDEDRNLCLIAYPLKGDHGPVDIVDNSDCE PKSKLLRWTNKKHHVLETEKSPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVEKKGTVS SQLKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTCRYEVPCVLDLKMGTRQHGDDASE EKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRY LRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKEWPEVTLDSDAEDLEDLSEESADE SAGAYAYKPLGASSVDVRMIDFAHTTCRLYGEDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE hide sequence

RefSeq Acc Id:	XP_008764786 ⟸ XM_008766564
- Peptide Label:	isoform X1
- UniProtKB:	Q5XIU6 (UniProtKB/Swiss-Prot), Q9R0U1 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTP QYKGVVSVRFEEDEDRNLCLIAYPLKGDHGPVDIVDNSDCEPKSKLLRWTNKKHHVLETEKSPK DWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVEKKGTVSSQLKHYNPWSMKCHQQQLQRMKE NAKHRNQYKFILLENLTCRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVC GMQVYQAGTGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQ ESYRFYSSSLLVIYDGKEWPEVTLDSDAEDLEDLSEESADESAGAYAYKPLGASSVDVRMIDFA HTTCRLYGEDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE hide sequence

RefSeq Acc Id:

ENSRNOP00000071056 ⟸ ENSRNOT00000077078

RefSeq Acc Id:

ENSRNOP00000027584 ⟸ ENSRNOT00000027584

RefSeq Acc Id:	XP_038937972 ⟸ XM_039082044
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038937973 ⟸ XM_039082045
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038937971 ⟸ XM_039082043
- Peptide Label:	isoform X1
- UniProtKB:	Q5XIU6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:

ENSRNOP00000092455 ⟸ ENSRNOT00000099109

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R0U1-F1-model_v2	AlphaFold	Q9R0U1	1-425	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696324

Promoter ID:

EPDNEW_R6840

Type:

initiation region

Name:

Ip6k2_1

Description:

inositol hexakisphosphate kinase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	117,574,173 - 117,574,233	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620529	AgrOrtholog
BioCyc Gene	G2FUF-29116	BioCyc
BioCyc Pathway	PWY-6369 [inositol diphosphates biosynthesis]	BioCyc
Ensembl Genes	ENSRNOG00000020361	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000027584	ENTREZGENE
	ENSRNOP00000027584.5	UniProtKB/TrEMBL
	ENSRNOP00000071056	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000092455.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027584	ENTREZGENE
	ENSRNOT00000027584.5	UniProtKB/TrEMBL
	ENSRNOT00000077078	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000099109.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.470.160	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7112777	IMAGE-MGC_LOAD
InterPro	IPK	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IPK_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:59268	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93905	IMAGE-MGC_LOAD
NCBI Gene	59268	ENTREZGENE
PANTHER	PTHR12400	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	IPK	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ip6k2	PhenoGen
UniProt	A0A8I6AHJ9_RAT	UniProtKB/TrEMBL
	A0A8L2UKG6	ENTREZGENE, UniProtKB/TrEMBL
	IP6K2_RAT	UniProtKB/Swiss-Prot
	Q5XIU6	ENTREZGENE
	Q9R0U1	ENTREZGENE
UniProt Secondary	Q5XIU6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-02-26	Ip6k2	inositol hexakisphosphate kinase 2	Ihpk2	inositol hexaphosphate kinase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Ihpk2	inositol hexaphosphate kinase 2	Pius	PiUS protein	Symbol and Name updated	1299863	APPROVED
2002-08-07	Pius	PiUS protein			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_protein	424 amino acids; 51 kDa	633655

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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