Ncoa4 (nuclear receptor coactivator 4)

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Gene: Ncoa4 (nuclear receptor coactivator 4) Rattus norvegicus

Analyze

Symbol:

Ncoa4

Name:

nuclear receptor coactivator 4

RGD ID:

1563014

Description:

Predicted to enable transcription coactivator activity. Involved in response to hormone. Predicted to be located in autolysosome. Orthologous to human NCOA4 (nuclear receptor coactivator 4); PARTICIPATES IN iron homeostasis pathway; thyroid cancer pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC72479

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NCOA4 (nuclear receptor coactivator 4)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Ncoa4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ncoa4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NCOA4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NCOA4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ncoa4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NCOA4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NCOA4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ncoa4 (nuclear receptor coactivator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NCOA4 (nuclear receptor coactivator 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ncoa4 (nuclear receptor coactivator 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ncoa4 (nuclear receptor coactivator 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	7,389,222 - 7,409,564 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	7,366,542 - 7,409,641 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	16	7,366,542 - 7,409,556 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	7,401,738 - 7,422,128 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	8,546,594 - 8,566,985 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	7,399,986 - 7,420,330 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	8,302,950 - 8,323,294 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	8,302,950 - 8,323,293 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	8,219,983 - 8,240,326 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	7,642,116 - 7,662,460 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	7,789,196 - 7,809,198 (-)	NCBI		Celera
Cytogenetic Map	16	p16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

invasive ductal carcinoma (ISO)

megacolon (ISO)

ovarian carcinoma (ISO)

polycystic ovary syndrome (ISO)

prostate cancer (ISO)

Thyroid Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3-methyladenine (EXP,ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetaldehyde (ISO)

aflatoxin B1 (ISO)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

artesunate (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chloropicrin (ISO)

chloroquine (EXP,ISO)

chlorpyrifos (ISO)

choline (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

clozapine (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

desferrioxamine B (ISO)

diarsenic trioxide (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diquat (ISO)

doxorubicin (EXP,ISO)

erastin (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

ferric ammonium citrate (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

furan (EXP)

genistein (ISO)

glycidyl methacrylate (ISO)

hexadecanoic acid (ISO)

hydralazine (ISO)

indometacin (EXP)

L-methionine (ISO)

lead(0) (ISO)

leflunomide (ISO)

methapyrilene (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

N-acetyl-L-cysteine (ISO)

nickel atom (ISO)

nickel dichloride (ISO)

nickel sulfate (ISO)

nitrofen (EXP)

penconazole (ISO)

progesterone (ISO)

propiconazole (ISO)

quercetin (ISO)

raloxifene (ISO)

resveratrol (ISO)

silibinin (ISO)

tamoxifen (ISO)

testosterone (ISO)

thapsigargin (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

wortmannin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular iron ion homeostasis (ISO)

positive regulation of DNA-templated transcription (IEA)

protein targeting to lysosome (ISO)

response to hormone (IBA,IEP)

Cellular Component

autolysosome (ISO)

Molecular Function

protein binding (ISO)

transcription coactivator activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

iron homeostasis pathway (ISO)

thyroid cancer pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease.	Bogdan AR, etal., Trends Biochem Sci. 2016 Mar;41(3):274-86. doi: 10.1016/j.tibs.2015.11.012. Epub 2015 Dec 23.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer.	Hu YC, etal., J Biol Chem. 2004 Aug 6;279(32):33438-46. Epub 2004 May 27.
4.	Loss of androgen receptor associated protein 70 (ARA70) expression in a subset of HER2-positive breast cancers.	Kollara A, etal., Breast Cancer Res Treat. 2001 Jun;67(3):245-53.
5.	Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.	Lane DJ, etal., Biochim Biophys Acta. 2015 May;1853(5):1130-44. doi: 10.1016/j.bbamcr.2015.01.021. Epub 2015 Feb 4.
6.	Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer.	Li P, etal., Am J Pathol. 2002 Oct;161(4):1467-74.
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	Evaluation of steroid receptors, coregulators, and molecules associated with uterine receptivity in secretory endometria from untreated women with polycystic ovary syndrome.	Quezada S, etal., Fertil Steril. 2006 Apr;85(4):1017-26. Epub 2006 Mar 9.
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation
13.	Activation of androgen receptor-associated protein 70 (ARA70) mRNA expression in ovarian cancer.	Shaw PA, etal., Gynecol Oncol. 2001 Feb;80(2):132-8.
14.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15.	Direct regulation of androgen receptor-associated protein 70 by thyroid hormone and its receptors.	Tai PJ, etal., Endocrinology. 2007 Jul;148(7):3485-95. Epub 2007 Apr 5.

Additional References at PubMed

PMID:8889548	PMID:18614015	PMID:25327288

Genomics

Comparative Map Data

Ncoa4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	7,389,222 - 7,409,564 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	7,366,542 - 7,409,641 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	16	7,366,542 - 7,409,556 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	7,401,738 - 7,422,128 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	8,546,594 - 8,566,985 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	7,399,986 - 7,420,330 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	8,302,950 - 8,323,294 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	8,302,950 - 8,323,293 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	8,219,983 - 8,240,326 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	7,642,116 - 7,662,460 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	7,789,196 - 7,809,198 (-)	NCBI		Celera
Cytogenetic Map	16	p16	NCBI

NCOA4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	46,005,088 - 46,030,623 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	46,005,088 - 46,030,623 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	51,565,199 - 51,590,734 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	51,242,373 - 51,260,738 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	51,242,372 - 51,260,738	NCBI
Celera	10	42,865,707 - 42,891,332 (+)	NCBI		Celera
Cytogenetic Map	10	q11.22	NCBI
HuRef	10	45,675,105 - 45,698,057 (+)	NCBI		HuRef
CHM1_1	10	51,847,046 - 51,872,689 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	46,885,972 - 46,911,498 (-)	NCBI		T2T-CHM13v2.0

Ncoa4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	31,881,884 - 31,901,210 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	31,881,822 - 31,901,812 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	32,159,879 - 32,179,855 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	32,159,865 - 32,179,855 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	32,973,078 - 32,992,549 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	30,988,901 - 31,008,372 (+)	NCBI		MGSCv36	mm8
Celera	14	28,418,721 - 28,438,204 (+)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	19.4	NCBI

Ncoa4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955556	392,398 - 412,166 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955556	392,412 - 413,643 (+)	NCBI	ChiLan1.0	ChiLan1.0

NCOA4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	10	58,889,371 - 58,914,924 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	43,159,014 - 43,184,558 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	46,420,952 - 46,446,479 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	46,420,952 - 46,443,223 (-)	Ensembl	panpan1.1		panPan2

NCOA4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	1,801,655 - 1,867,705 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	1,802,678 - 1,825,020 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	2,036,132 - 2,102,171 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	1,979,010 - 2,045,152 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	28	1,776,104 - 1,842,163 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	1,812,773 - 1,879,059 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	1,945,148 - 2,011,231 (-)	NCBI		UU_Cfam_GSD_1.0

Ncoa4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	79,174,126 - 79,199,709 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936728	376,852 - 402,539 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936728	376,915 - 402,539 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NCOA4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	90,505,110 - 90,531,118 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	90,505,614 - 90,531,302 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	98,548,146 - 98,573,846 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NCOA4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	41,813,018 - 41,836,974 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	41,826,320 - 41,837,505 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	1,522,166 - 1,546,119 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ncoa4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624928	18,148 - 30,594 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624928	6,298 - 32,051 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ncoa4
116 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	310
Count of miRNA genes:	113
Interacting mature miRNAs:	141
Transcripts:	ENSRNOT00000026803, ENSRNOT00000066062
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	1	9639137	Rat
1600369	Hcas8	Hepatocarcinoma susceptibility QTL 8			liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	16	1	22477621	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26727669	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26727669	Rat
1582235	Insul8	Insulin level QTL 8	3.3	0.0063	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	16	1	26727669	Rat
9590151	Scort8	Serum corticosterone level QTL 8	8.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	16	1	30836262	Rat
2302380	Slep6	Serum leptin concentration QTL 6	3.36		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	1	32139025	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33418960	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39533930	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39533930	Rat
631561	Hcuc2	Hepatic copper content QTL 2	2.8		liver copper amount (VT:0003065)	liver total copper weight (CMO:0001507)	16	1	39533949	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	1	43534949	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	1	44588133	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	44977551	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	832236	46053497	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	832236	59492508	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	832236	59492508	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	832236	59492508	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	832236	59492508	Rat
2301406	Kidm39	Kidney mass QTL 39		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	16	2851709	15884239	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3380150	21361552	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3380150	43025077	Rat
737825	Alc13	Alcohol consumption QTL 13	4.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	16039848	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	16	4227609	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4227609	43025077	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4227609	46975965	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	4227609	48972724	Rat
61338	Bp23	Blood pressure QTL 23	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	49227609	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	60252231	Rat
61372	Bp40	Blood pressure QTL 40	2.2		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	16	4227730	17696785	Rat

Markers in Region

D12Got38

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	7,396,808 - 7,396,980 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	8,310,539 - 8,310,710	NCBI	Rnor6.0
Rnor_5.0	16	8,227,571 - 8,227,742	UniSTS	Rnor5.0
RGSC_v3.4	16	7,649,704 - 7,649,876	RGD	RGSC3.4
RGSC_v3.4	16	7,649,705 - 7,649,876	UniSTS	RGSC3.4
RGSC_v3.1	16	7,649,702 - 7,649,874	RGD
Celera	16	7,801,780 - 7,801,951	UniSTS
Cytogenetic Map	16	p16	UniSTS

RH132366

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	7,405,258 - 7,405,472 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	8,318,989 - 8,319,202	NCBI	Rnor6.0
Rnor_5.0	16	8,236,021 - 8,236,234	UniSTS	Rnor5.0
RGSC_v3.4	16	7,658,155 - 7,658,368	UniSTS	RGSC3.4
Celera	16	7,793,288 - 7,793,501	UniSTS
RH 3.4 Map	16	65.3	UniSTS
Cytogenetic Map	16	p16	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001034008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI031008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI112421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC160817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB758330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB806310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV119475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV795771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226225	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000026803 ⟹ ENSRNOP00000026803

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	7,366,542 - 7,409,556 (+)	Ensembl
Rnor_6.0 Ensembl	16	8,309,239 - 8,323,293 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000066062 ⟹ ENSRNOP00000061299

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	7,366,542 - 7,409,556 (+)	Ensembl
Rnor_6.0 Ensembl	16	8,302,950 - 8,323,293 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095475 ⟹ ENSRNOP00000085149

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	7,398,798 - 7,409,641 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117357 ⟹ ENSRNOP00000085575

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	7,395,642 - 7,409,556 (+)	Ensembl

RefSeq Acc Id:

NM_001034007 ⟹ NP_001029179

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	7,395,509 - 7,409,564 (+)	NCBI
Rnor_6.0	16	8,309,239 - 8,323,294 (+)	NCBI
Rnor_5.0	16	8,219,983 - 8,240,326 (+)	NCBI
RGSC_v3.4	16	7,642,116 - 7,662,460 (+)	RGD
Celera	16	7,789,196 - 7,803,251 (-)	NCBI

Sequence:

show sequence

GCATGTTCACGCAGCAGTTTTCGTCGCGGGGTCGCACCACCCGGAACAGTGAGCAGAATGAATA
CATCCCTGGAGCAGAGTGGCTGCTGCAGTAGTAGAGAGACACTTCTGAGGTGCAGTGATGCAAG
GAGGGAGCTGGAGCTTGCGATTGGTGGAGTCCTCCGGGCCGAGCAGCAAATGAAAGATAATCTA
CGAGAGGTGAAAGCTCAGATTCACAGCTGCATTAGTCGCCACCTGGAATGCCTTCGAAGCCGAG
AGGTGTGGCTCAACGAGCAGGTGGATCTCATCTATCAGCTGAAGGAGGAGACGCTGCAGCAGCA
GGCTCAGCAGCTGTACTGGCTAATGGGCCAATTCAATTGTCTTATTCATCAACTGGAGATTACC
CAGAACAAGGATCTTGCCAATCAAGTCGCGCTGTGCTTGGAGAGACTGGGCAGTTTGACCCTTA
AGCCTGAGGATTCTACTGTCCTGCTCTTTGAAGCAGATGCATCTGCCCTGCGTCAGACCATCAC
CACGTTTGGGTCCCTCAAGACCATTCAAATTCCTGAGCACCTGATGGCTCATCCTAGTTCTTCA
AGTGTCAGGCCTTTCCTGGAGAAAAGAGGTTATACCCAGGTGCCAGAGCAGAAGTCAGCATCCA
GCGGCACAGCTGTTTCTCTCAGTGAATGGCTTCTTGTAAGCAAACCTGCCATTGGTCCTCAGGC
TCCATACGTACCCAGTACCAACCCACAGGACTGGCTCACCCCAAAACAGACCTTGGAGAACAGT
CAGACTTCTGCCAGAATCTGCAGCGATGCCTGGGGCAATCTGAAGGGCTTAGAAAACTGGCTCC
TTAACAGTCATCAACAAGAAATTCCTGGAAAACCAAGTTCCTCAAAATGTAATAGCCATTGTAG
CACCAGTTCTTTCTCTACTGAAGATGAAAAGGTTGAAGATGTAGAGGTCCTCGATCAAGACGAG
CTGGACCTGTCTGATTGGTTGGTGACTCCTCAGGAACCCCGTGATCTGGAGAAGCCTGTGAATG
GCCGCTCTGACACCAGTGACAAGTTTAAGCTCTTGTTCCAGGTGTTCAGAGAGCCCTACAATGT
GAATGATTGGCTTGTCAAGCCTGACTCCTGTACCAACTGTCAGGGTAACCAGCCCAGAGGTGTG
GAGATTGAGAACCTGGGCAATCTGAAATGCCTGAATGACCACTTGGAGGCTAAAAAGTCATTGC
CAGTCCCCGGCGTAATCACCGAGGGCTGGCTTGTCCAGAACCATCAGGACACATGTAAAGTAGA
GGAAGTCTGCAAAGCCAACGAGCCCTGCACCAGCTTTGCAGAGTGTGTGTGTGATGACAGCTGT
GAGAAGGAAGCGATGCATAAATGGCTTCTGAAGAAAGAAGGGAAGGACAAGAATGGAATGCCTA
TGGGACCCAAATCTGAGTCTGAGAAACACAGAGAGTCCCTGTCTCTGTGGCTTTGCCCTTCTAG
AAATGAGCTAACAGAACACGCTAAGACACCCAAGACTACGGCTCCTGCTAGAATTGCTGACTCC
TTCCACATCATAAGGAATAGCTCCTTGTCAGAGTGGCTTATTGGGCCTACATGCAAAGGAGGAG
GCCCCAAGGAAGTGCCCAATATGGAGGAGAGAGCTAGCAAAGAAATGCTTAAAAGCCCCATGGC
CACTTACTGGCGTCCTTTTAACACTGCTGACTGGGTCTTACCAGGAAAGAAAGTGGGAAACCTT
AGTCAGTTCTCCTCGGGAGAAGATAAGTGGCTACTTCGAAAGAAGGCACAGGAAGTATTTCTTA
ATTCACCCCTACAAGAAGAACGTAACTTTCGCTCAGATTGTTACGGCCTCCCGGCAGTTTGTGA
TCTCTTTGCCTGTATGCAGCTTAAAGTTGATAAGGACAAATGGCTGTACAGAGCCCCTCTTCAG
ATGTGAAGGAGTGGATACTAGAGTGGAGCATCTTCCCTGCAGATTCTCGCACATCGTGAGCTGA
GTGACCGTGACCTGCCAACCATTGTGCATTCCAGGCCTGACTAGTCGGCTTAGTTCCTCTCCTG
CTTAGTTTTGAACTAGTAAACAGAAATCATAAACTGAGTTAAGTCTGTGAGTTGAGGCTTGAAG
TGAAGGTGATTATTCTTATGGAAGCAGTAACTTGATTGACTCCCATAGTAGAAACCGCATCCCG
GTACACAGGCCTTTACAGCTTCTGTAACAAACACTAGTTTTAAAAGTGAAATATTTCTACATCA
AGTGTGTTAATGTGTTCAAGGTAGTAAAGCTCTCTAGCTTTCGTCCTTTAGCTGTCTCTCCTGT
CACTGGCTCCTAGTGATTTGGGTTTTTTTTTTTTTTTTTTTTTTTTTGGTTCAGTTGATATATA
GAATATTTCACACAAATAATTAACCTTGCCAATACAGTATATTTTTCCCTACTGAATCTCTATT
AGTTACATTGCAATTTTGATACTCACCAGATATTTAGCCTACATGTCATTTCTAACATTTCTCA
TTTGAAAAGAAAAGTTGCCTTTATTTCTTCCCAAGTATCCAGTAAGCTCTTTGAAAGGACTTAC
CGTTTCAGGACCACTCTTAGGGCAATCAGAGCCCCCTAAAGTCCTACAAACCTTGGCTTTAACT
AAGGAGTCCTAGGCCAATTAAAGCAGAAGTAAAATGTGCTAGGAATGAATGTAGTACCTGAACC
ACTCATCGTCCTAAGGATTTATTGGTGCATCCTGTGGAAGTGGAAGCTGAGCTTGACACCTGGT
GCTCTTAACTAGGGATACAGTCCATGTCCTGTCACTTCAAGCACAGCATCCTGAACCTCCAAAA
GTACAGTGCAGTGATGTCTTGACTAACAGGCTGTGCTCAATACTTGTGCCTTGGAGTGTTTCCC
TGAAACTTCACAGAACTGACATCCTTGGGTTATGTCTGTATTTTAGAAAGGAGAGTAGCAGGAT
TGATCTTTTACAATTCTTCAGGATAGCAGCTGCTTTCTAAGCTTTGAACTATTAATATTAAGCC
TCTGAGTTGCCTATGCTATTGGAAGTACTTTTGGGAGAATTTTATGGTTCTTCCCACAGTGACA
TTACCATAGAGCTTTACTAAAGCTCCAAATCATAGCTGAAAAGAGCTCCATATTTTCTTACGTC
CCCCCAGATGCCACTGAGTATTAAATCGTTGGTAGGTAAAAACAATTTTAAGGAGCCTTTCCAA
CATTTTAGGTTGCGGGGAACTTTGTGGTTTCTTTTTTGAGGTCTAACACACTGTATTTCACATT
ATTAAAACATAATTTTAAGTTAATCACTATTGCTAATGTTATATAAAACTTTCTTTTGCATTGA
TAAGTTTTATATCTCCATTAAAAGCATAATTGCCACATCACAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001034008 ⟹ NP_001029180

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	7,389,222 - 7,409,564 (+)	NCBI
Rnor_6.0	16	8,302,950 - 8,323,294 (+)	NCBI
Rnor_5.0	16	8,219,983 - 8,240,326 (+)	NCBI
RGSC_v3.4	16	7,642,116 - 7,662,460 (+)	RGD
Celera	16	7,789,196 - 7,809,198 (-)	RGD

Sequence:

show sequence

TCTGCCTTCAGGGTCCGGCTCCTTCCGTGGCTGAGTGTCTGGGTCGGTCCAAGGTCCGCTCGGA
TCACCGGAAGAAGCCCTGCCAGCTGGAACAGTGAGCAGAATGAATACATCCCTGGAGCAGAGTG
GCTGCTGCAGTAGTAGAGAGACACTTCTGAGGTGCAGTGATGCAAGGAGGGAGCTGGAGCTTGC
GATTGGTGGAGTCCTCCGGGCCGAGCAGCAAATGAAAGATAATCTACGAGAGGTGAAAGCTCAG
ATTCACAGCTGCATTAGTCGCCACCTGGAATGCCTTCGAAGCCGAGAGGTGTGGCTCAACGAGC
AGGTGGATCTCATCTATCAGCTGAAGGAGGAGACGCTGCAGCAGCAGGCTCAGCAGCTGTACTG
GCTAATGGGCCAATTCAATTGTCTTATTCATCAACTGGAGATTACCCAGAACAAGGATCTTGCC
AATCAAGTCGCGCTGTGCTTGGAGAGACTGGGCAGTTTGACCCTTAAGCCTGAGGATTCTACTG
TCCTGCTCTTTGAAGCAGATGCATCTGCCCTGCGTCAGACCATCACCACGTTTGGGTCCCTCAA
GACCATTCAAATTCCTGAGCACCTGATGGCTCATCCTAGTTCTTCAAGTGTCAGGCCTTTCCTG
GAGAAAAGAGGTTATACCCAGGTGCCAGAGCAGAAGTCAGCATCCAGCGGCACAGCTGTTTCTC
TCAGTGAATGGCTTCTTGTAAGCAAACCTGCCATTGGTCCTCAGGCTCCATACGTACCCAGTAC
CAACCCACAGGACTGGCTCACCCCAAAACAGACCTTGGAGAACAGTCAGACTTCTGCCAGAATC
TGCAGCGATGCCTGGGGCAATCTGAAGGGCTTAGAAAACTGGCTCCTTAACAGTCATCAACAAG
AAATTCCTGGAAAACCAAGTTCCTCAAAATGTAATAGCCATTGTAGCACCAGTTCTTTCTCTAC
TGAAGATGAAAAGGTTGAAGATGTAGAGGTCCTCGATCAAGACGAGCTGGACCTGTCTGATTGG
TTGGTGACTCCTCAGGAACCCCGTGATCTGGAGAAGCCTGTGAATGGCCGCTCTGACACCAGTG
ACAAGTTTAAGCTCTTGTTCCAGGTGTTCAGAGAGCCCTACAATGTGAATGATTGGCTTGTCAA
GCCTGACTCCTGTACCAACTGTCAGGGTAACCAGCCCAGAGGTGTGGAGATTGAGAACCTGGGC
AATCTGAAATGCCTGAATGACCACTTGGAGGCTAAAAAGTCATTGCCAGTCCCCGGCGTAATCA
CCGAGGGCTGGCTTGTCCAGAACCATCAGGACACATGTAAAGTAGAGGAAGTCTGCAAAGCCAA
CGAGCCCTGCACCAGCTTTGCAGAGTGTGTGTGTGATGACAGCTGTGAGAAGGAAGCGATGCAT
AAATGGCTTCTGAAGAAAGAAGGGAAGGACAAGAATGGAATGCCTATGGGACCCAAATCTGAGT
CTGAGAAACACAGAGAGTCCCTGTCTCTGTGGCTTTGCCCTTCTAGAAATGAGCTAACAGAACA
CGCTAAGACACCCAAGACTACGGCTCCTGCTAGAATTGCTGACTCCTTCCACATCATAAGGAAT
AGCTCCTTGTCAGAGTGGCTTATTGGGCCTACATGCAAAGGAGGAGGCCCCAAGGAAGTGCCCA
ATATGGAGGAGAGAGCTAGCAAAGAAATGCTTAAAAGCCCCATGGCCACTTACTGGCGTCCTTT
TAACACTGCTGACTGGGTCTTACCAGGAAAGAAAGTGGGAAACCTTAGTCAGTTCTCCTCGGGA
GAAGATAAGTGGCTACTTCGAAAGAAGGCACAGGAAGTATTTCTTAATTCACCCCTACAAGAAG
AACGTAACTTTCGCTCAGATTGTTACGGCCTCCCGGCAGTTTGTGATCTCTTTGCCTGTATGCA
GCTTAAAGTTGATAAGGACAAATGGCTGTACAGAGCCCCTCTTCAGATGTGAAGGAGTGGATAC
TAGAGTGGAGCATCTTCCCTGCAGATTCTCGCACATCGTGAGCTGAGTGACCGTGACCTGCCAA
CCATTGTGCATTCCAGGCCTGACTAGTCGGCTTAGTTCCTCTCCTGCTTAGTTTTGAACTAGTA
AACAGAAATCATAAACTGAGTTAAGTCTGTGAGTTGAGGCTTGAAGTGAAGGTGATTATTCTTA
TGGAAGCAGTAACTTGATTGACTCCCATAGTAGAAACCGCATCCCGGTACACAGGCCTTTACAG
CTTCTGTAACAAACACTAGTTTTAAAAGTGAAATATTTCTACATCAAGTGTGTTAATGTGTTCA
AGGTAGTAAAGCTCTCTAGCTTTCGTCCTTTAGCTGTCTCTCCTGTCACTGGCTCCTAGTGATT
TGGGTTTTTTTTTTTTTTTTTTTTTTTTTGGTTCAGTTGATATATAGAATATTTCACACAAATA
ATTAACCTTGCCAATACAGTATATTTTTCCCTACTGAATCTCTATTAGTTACATTGCAATTTTG
ATACTCACCAGATATTTAGCCTACATGTCATTTCTAACATTTCTCATTTGAAAAGAAAAGTTGC
CTTTATTTCTTCCCAAGTATCCAGTAAGCTCTTTGAAAGGACTTACCGTTTCAGGACCACTCTT
AGGGCAATCAGAGCCCCCTAAAGTCCTACAAACCTTGGCTTTAACTAAGGAGTCCTAGGCCAAT
TAAAGCAGAAGTAAAATGTGCTAGGAATGAATGTAGTACCTGAACCACTCATCGTCCTAAGGAT
TTATTGGTGCATCCTGTGGAAGTGGAAGCTGAGCTTGACACCTGGTGCTCTTAACTAGGGATAC
AGTCCATGTCCTGTCACTTCAAGCACAGCATCCTGAACCTCCAAAAGTACAGTGCAGTGATGTC
TTGACTAACAGGCTGTGCTCAATACTTGTGCCTTGGAGTGTTTCCCTGAAACTTCACAGAACTG
ACATCCTTGGGTTATGTCTGTATTTTAGAAAGGAGAGTAGCAGGATTGATCTTTTACAATTCTT
CAGGATAGCAGCTGCTTTCTAAGCTTTGAACTATTAATATTAAGCCTCTGAGTTGCCTATGCTA
TTGGAAGTACTTTTGGGAGAATTTTATGGTTCTTCCCACAGTGACATTACCATAGAGCTTTACT
AAAGCTCCAAATCATAGCTGAAAAGAGCTCCATATTTTCTTACGTCCCCCCAGATGCCACTGAG
TATTAAATCGTTGGTAGGTAAAAACAATTTTAAGGAGCCTTTCCAACATTTTAGGTTGCGGGGA
ACTTTGTGGTTTCTTTTTTGAGGTCTAACACACTGTATTTCACATTATTAAAACATAATTTTAA
GTTAATCACTATTGCTAATGTTATATAAAACTTTCTTTTGCATTGATAAGTTTTATATCTCCAT
TAAAAGCATAATTGCCACATCACAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006252660 ⟹ XP_006252722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	7,395,590 - 7,409,564 (+)	NCBI
Rnor_6.0	16	8,309,306 - 8,323,289 (+)	NCBI
Rnor_5.0	16	8,219,983 - 8,240,326 (+)	NCBI

Sequence:

show sequence

AGACTGCGCATGCGTGCGGGAAGCCCTGGGAGACCGATTTCACCAGCTGCTCCCGGAAAGGGCA
ACGGGAAGCCTAGAAAGCTGTTTGAGTCACTGCTACTCTAGCTTAATTTTTACCGTTATTTTGT
TTTCGAAACAGAAAAAAACTTCTTTAGTCTTGCCATTAAGTGGCAGAATTTTGCAGCCGTTTTT
TTCAGTTACTGCTTAGAGTTTATGTGCTGGGTCTGGTAGCTACTTATGAAAGCAAACTAGAGCG
CCGCGGAGGGTCAAGAATTTGAACTGGACTCAACTTAAGATCTGTATACTCTTTTGAGATAATG
CGCAGTGATTAAAAAACCCCTTTTCACTGAGAGAAGAAACAGCAAGTGGTGAAGTCAAGAAATG
GCTCAAGGAACAGTGAGCAGAATGAATACATCCCTGGAGCAGAGTGGCTGCTGCAGTAGTAGAG
AGACACTTCTGAGGTGCAGTGATGCAAGGAGGGAGCTGGAGCTTGCGATTGGTGGAGTCCTCCG
GGCCGAGCAGCAAATGAAAGATAATCTACGAGAGGTGAAAGCTCAGATTCACAGCTGCATTAGT
CGCCACCTGGAATGCCTTCGAAGCCGAGAGGTGTGGCTCAACGAGCAGGTGGATCTCATCTATC
AGCTGAAGGAGGAGACGCTGCAGCAGCAGGCTCAGCAGCTGTACTGGCTAATGGGCCAATTCAA
TTGTCTTATTCATCAACTGGAGATTACCCAGAACAAGGATCTTGCCAATCAAGTCGCGCTGTGC
TTGGAGAGACTGGGCAGTTTGACCCTTAAGCCTGAGGATTCTACTGTCCTGCTCTTTGAAGCAG
ATGCATCTGCCCTGCGTCAGACCATCACCACGTTTGGGTCCCTCAAGACCATTCAAATTCCTGA
GCACCTGATGGCTCATCCTAGTTCTTCAAGTGTCAGGCCTTTCCTGGAGAAAAGAGGTTATACC
CAGGTGCCAGAGCAGAAGTCAGCATCCAGCGGCACAGCTGTTTCTCTCAGTGAATGGCTTCTTG
TAAGCAAACCTGCCATTGGTCCTCAGGCTCCATACGTACCCAGTACCAACCCACAGGACTGGCT
CACCCCAAAACAGACCTTGGAGAACAGTCAGACTTCTGCCAGAATCTGCAGCGATGCCTGGGGC
AATCTGAAGGGCTTAGAAAACTGGCTCCTTAACAGTCATCAACAAGAAATTCCTGGAAAACCAA
GTTCCTCAAAATGTAATAGCCATTGTAGCACCAGTTCTTTCTCTACTGAAGATGAAAAGGTTGA
AGATGTAGAGGTCCTCGATCAAGACGAGCTGGACCTGTCTGATTGGTTGGTGACTCCTCAGGAA
CCCCGTGATCTGGAGAAGCCTGTGAATGGCCGCTCTGACACCAGTGACAAGTTTAAGCTCTTGT
TCCAGGTGTTCAGAGAGCCCTACAATGTGAATGATTGGCTTGTCAAGCCTGACTCCTGTACCAA
CTGTCAGGGTAACCAGCCCAGAGGTGTGGAGATTGAGAACCTGGGCAATCTGAAATGCCTGAAT
GACCACTTGGAGGCTAAAAAGTCATTGCCAGTCCCCGGCGTAATCACCGAGGGCTGGCTTGTCC
AGAACCATCAGGACACATGTAAAGTAGAGGAAGTCTGCAAAGCCAACGAGCCCTGCACCAGCTT
TGCAGAGTGTGTGTGTGATGACAGCTGTGAGAAGGAAGCGATGCATAAATGGCTTCTGAAGAAA
GAAGGGAAGGACAAGAATGGAATGCCTATGGGACCCAAATCTGAGTCTGAGAAACACAGAGAGT
CCCTGTCTCTGTGGCTTTGCCCTTCTAGAAATGAGCTAACAGAACACGCTAAGACACCCAAGAC
TACGGCTCCTGCTAGAATTGCTGACTCCTTCCACATCATAAGGAATAGCTCCTTGTCAGAGTGG
CTTATTGGGCCTACATGCAAAGGAGGAGGCCCCAAGGAAGTGCCCAATATGGAGGAGAGAGCTA
GCAAAGAAATGCTTAAAAGCCCCATGGCCACTTACTGGCGTCCTTTTAACACTGCTGACTGGGT
CTTACCAGGAAAGAAAGTGGGAAACCTTAGTCAGTTCTCCTCGGGAGAAGATAAGTGGCTACTT
CGAAAGAAGGCACAGGAAGTATTTCTTAATTCACCCCTACAAGAAGAACGTAACTTTCGCTCAG
ATTGTTACGGCCTCCCGGCAGTTTGTGATCTCTTTGCCTGTATGCAGCTTAAAGTTGATAAGGA
CAAATGGCTGTACAGAGCCCCTCTTCAGATGTGAAGGAGTGGATACTAGAGTGGAGCATCTTCC
CTGCAGATTCTCGCACATCGTGAGCTGAGTGACCGTGACCTGCCAACCATTGTGCATTCCAGGC
CTGACTAGTCGGCTTAGTTCCTCTCCTGCTTAGTTTTGAACTAGTAAACAGAAATCATAAACTG
AGTTAAGTCTGTGAGTTGAGGCTTGAAGTGAAGGTGATTATTCTTATGGAAGCAGTAACTTGAT
TGACTCCCATAGTAGAAACCGCATCCCGGTACACAGGCCTTTACAGCTTCTGTAACAAACACTA
GTTTTAAAAGTGAAATATTTCTACATCAAGTGTGTTAATGTGTTCAAGGTAGTAAAGCTCTCTA
GCTTTCGTCCTTTAGCTGTCTCTCCTGTCACTGGCTCCTAGTGATTTGGGTTTTTTTTTTTTTT
TTTTTTTTTTTGGTTCAGTTGATATATAGAATATTTCACACAAATAATTAACCTTGCCAATACA
GTATATTTTTCCCTACTGAATCTCTATTAGTTACATTGCAATTTTGATACTCACCAGATATTTA
GCCTACATGTCATTTCTAACATTTCTCATTTGAAAAGAAAAGTTGCCTTTATTTCTTCCCAAGT
ATCCAGTAAGCTCTTTGAAAGGACTTACCGTTTCAGGACCACTCTTAGGGCAATCAGAGCCCCC
TAAAGTCCTACAAACCTTGGCTTTAACTAAGGAGTCCTAGGCCAATTAAAGCAGAAGTAAAATG
TGCTAGGAATGAATGTAGTACCTGAACCACTCATCGTCCTAAGGATTTATTGGTGCATCCTGTG
GAAGTGGAAGCTGAGCTTGACACCTGGTGCTCTTAACTAGGGATACAGTCCATGTCCTGTCACT
TCAAGCACAGCATCCTGAACCTCCAAAAGTACAGTGCAGTGATGTCTTGACTAACAGGCTGTGC
TCAATACTTGTGCCTTGGAGTGTTTCCCTGAAACTTCACAGAACTGACATCCTTGGGTTATGTC
TGTATTTTAGAAAGGAGAGTAGCAGGATTGATCTTTTACAATTCTTCAGGATAGCAGCTGCTTT
CTAAGCTTTGAACTATTAATATTAAGCCTCTGAGTTGCCTATGCTATTGGAAGTACTTTTGGGA
GAATTTTATGGTTCTTCCCACAGTGACATTACCATAGAGCTTTACTAAAGCTCCAAATCATAGC
TGAAAAGAGCTCCATATTTTCTTACGTCCCCCCAGATGCCACTGAGTATTAAATCGTTGGTAGG
TAAAAACAATTTTAAGGAGCCTTTCCAACATTTTAGGTTGCGGGGAACTTTGTGGTTTCTTTTT
TGAGGTCTAACACACTGTATTTCACATTATTAAAACATAATTTTAAGTTAATCACTATTGCTAA
TGTTATATAAAACTTTCTTTTGCATTGATAAGTTTTATATCTCCATTAAAAGCATAATTGCCAC
A

hide sequence

Protein Sequences


Protein RefSeqs	NP_001029179	(Get FASTA)	NCBI Sequence Viewer
	NP_001029180	(Get FASTA)	NCBI Sequence Viewer
	XP_006252722	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI60817	(Get FASTA)	NCBI Sequence Viewer
	EDL88925	(Get FASTA)	NCBI Sequence Viewer
	EDL88926	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001029180 ⟸ NM_001034008

- UniProtKB:

B1H215 (UniProtKB/TrEMBL), A6KFW8 (UniProtKB/TrEMBL), A0A8I6A3B1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNTSLEQSGCCSSRETLLRCSDARRELELAIGGVLRAEQQMKDNLREVKAQIHSCISRHLECLR
SREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEITQNKDLANQVALCLERLGSL
TLKPEDSTVLLFEADASALRQTITTFGSLKTIQIPEHLMAHPSSSSVRPFLEKRGYTQVPEQKS
ASSGTAVSLSEWLLVSKPAIGPQAPYVPSTNPQDWLTPKQTLENSQTSARICSDAWGNLKGLEN
WLLNSHQQEIPGKPSSSKCNSHCSTSSFSTEDEKVEDVEVLDQDELDLSDWLVTPQEPRDLEKP
VNGRSDTSDKFKLLFQVFREPYNVNDWLVKPDSCTNCQGNQPRGVEIENLGNLKCLNDHLEAKK
SLPVPGVITEGWLVQNHQDTCKVEEVCKANEPCTSFAECVCDDSCEKEAMHKWLLKKEGKDKNG
MPMGPKSESEKHRESLSLWLCPSRNELTEHAKTPKTTAPARIADSFHIIRNSSLSEWLIGPTCK
GGGPKEVPNMEERASKEMLKSPMATYWRPFNTADWVLPGKKVGNLSQFSSGEDKWLLRKKAQEV
FLNSPLQEERNFRSDCYGLPAVCDLFACMQLKVDKDKWLYRAPLQM

hide sequence

RefSeq Acc Id:

NP_001029179 ⟸ NM_001034007

- UniProtKB:

B1H215 (UniProtKB/TrEMBL), A6KFW8 (UniProtKB/TrEMBL), A0A8I6A3B1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNTSLEQSGCCSSRETLLRCSDARRELELAIGGVLRAEQQMKDNLREVKAQIHSCISRHLECLR
SREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEITQNKDLANQVALCLERLGSL
TLKPEDSTVLLFEADASALRQTITTFGSLKTIQIPEHLMAHPSSSSVRPFLEKRGYTQVPEQKS
ASSGTAVSLSEWLLVSKPAIGPQAPYVPSTNPQDWLTPKQTLENSQTSARICSDAWGNLKGLEN
WLLNSHQQEIPGKPSSSKCNSHCSTSSFSTEDEKVEDVEVLDQDELDLSDWLVTPQEPRDLEKP
VNGRSDTSDKFKLLFQVFREPYNVNDWLVKPDSCTNCQGNQPRGVEIENLGNLKCLNDHLEAKK
SLPVPGVITEGWLVQNHQDTCKVEEVCKANEPCTSFAECVCDDSCEKEAMHKWLLKKEGKDKNG
MPMGPKSESEKHRESLSLWLCPSRNELTEHAKTPKTTAPARIADSFHIIRNSSLSEWLIGPTCK
GGGPKEVPNMEERASKEMLKSPMATYWRPFNTADWVLPGKKVGNLSQFSSGEDKWLLRKKAQEV
FLNSPLQEERNFRSDCYGLPAVCDLFACMQLKVDKDKWLYRAPLQM

hide sequence

RefSeq Acc Id:	XP_006252722 ⟸ XM_006252660
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A1Q3 (UniProtKB/TrEMBL), A0A8I6A3B1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAQGTVSRMNTSLEQSGCCSSRETLLRCSDARRELELAIGGVLRAEQQMKDNLREVKAQIHSCI SRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEITQNKDLANQVAL CLERLGSLTLKPEDSTVLLFEADASALRQTITTFGSLKTIQIPEHLMAHPSSSSVRPFLEKRGY TQVPEQKSASSGTAVSLSEWLLVSKPAIGPQAPYVPSTNPQDWLTPKQTLENSQTSARICSDAW GNLKGLENWLLNSHQQEIPGKPSSSKCNSHCSTSSFSTEDEKVEDVEVLDQDELDLSDWLVTPQ EPRDLEKPVNGRSDTSDKFKLLFQVFREPYNVNDWLVKPDSCTNCQGNQPRGVEIENLGNLKCL NDHLEAKKSLPVPGVITEGWLVQNHQDTCKVEEVCKANEPCTSFAECVCDDSCEKEAMHKWLLK KEGKDKNGMPMGPKSESEKHRESLSLWLCPSRNELTEHAKTPKTTAPARIADSFHIIRNSSLSE WLIGPTCKGGGPKEVPNMEERASKEMLKSPMATYWRPFNTADWVLPGKKVGNLSQFSSGEDKWL LRKKAQEVFLNSPLQEERNFRSDCYGLPAVCDLFACMQLKVDKDKWLYRAPLQM hide sequence

RefSeq Acc Id:

ENSRNOP00000026803 ⟸ ENSRNOT00000026803

RefSeq Acc Id:

ENSRNOP00000061299 ⟸ ENSRNOT00000066062

RefSeq Acc Id:

ENSRNOP00000085575 ⟸ ENSRNOT00000117357

RefSeq Acc Id:

ENSRNOP00000085149 ⟸ ENSRNOT00000095475

Protein Domains

Nuclear coactivator

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1H215-F1-model_v2	AlphaFold	B1H215	1-622	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563014	AgrOrtholog
BioCyc Gene	G2FUF-12118	BioCyc
Ensembl Genes	ENSRNOG00000019768	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000063221	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000026803	ENTREZGENE
	ENSRNOP00000026803.4	UniProtKB/TrEMBL
	ENSRNOP00000061299.1	UniProtKB/TrEMBL
	ENSRNOP00000085149.1	UniProtKB/TrEMBL
	ENSRNOP00000085575	ENTREZGENE
	ENSRNOP00000085575.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026803	ENTREZGENE
	ENSRNOT00000026803.6	UniProtKB/TrEMBL
	ENSRNOT00000066062.4	UniProtKB/TrEMBL
	ENSRNOT00000095475.1	UniProtKB/TrEMBL
	ENSRNOT00000117357	ENTREZGENE
	ENSRNOT00000117357.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7454028	IMAGE-MGC_LOAD
InterPro	ARA70	UniProtKB/TrEMBL
	NCoA-4	UniProtKB/TrEMBL
KEGG Report	rno:619385	UniProtKB/TrEMBL
MGC_CLONE	MGC:187270	IMAGE-MGC_LOAD
NCBI Gene	619385	ENTREZGENE
PANTHER	NUCLEAR RECEPTOR COACTIVATOR 4	UniProtKB/TrEMBL
	PTHR17085	UniProtKB/TrEMBL
Pfam	ARA70	UniProtKB/TrEMBL
PhenoGen	Ncoa4	PhenoGen
UniProt	A0A8I6A1Q3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A3B1	ENTREZGENE, UniProtKB/TrEMBL
	A6KFW8	ENTREZGENE
	B1H215	ENTREZGENE, UniProtKB/TrEMBL
	F7FLG1_RAT	UniProtKB/TrEMBL
UniProt Secondary	A6KFW8	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Ncoa4	nuclear receptor coactivator 4	Ncoa4_predicted	nuclear receptor coactivator 4 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	Ncoa4_predicted	nuclear receptor coactivator 4 (predicted)	Ncoa4	nuclear receptor coactivator 4	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	Ncoa4	nuclear receptor coactivator 4			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)