(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:731712 6480464 epigallocatechin gallate results in decreased expression of and results in decreased phosphorylation of RB1 protein CTD PMID:15142168 (-)-epigallocatechin 3-gallate increases expression ISO RGD:731712 6480464 epigallocatechin gallate results in increased expression of RB1 mRNA CTD PMID:18851785 (S)-colchicine multiple interactions ISO RGD:11219 6480464 Colchicine results in decreased phosphorylation of and results in decreased activity of RB1 protein CTD PMID:16495211 (S)-naringenin multiple interactions ISO RGD:731712 6480464 [naringenin metabolite co-treated with bisphenol A] results in increased expression of RB1 mRNA CTD PMID:36235125 (S)-nicotine multiple interactions ISO RGD:731712 6480464 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in increased phosphorylation of RB1 protein] more ... CTD PMID:16601104 more ... (S)-nicotine increases phosphorylation ISO RGD:11219 6480464 Nicotine results in increased phosphorylation of RB1 protein CTD PMID:15574422 (S)-nicotine increases expression ISO RGD:731712 6480464 Nicotine results in increased expression of RB1 protein modified form CTD PMID:20061081 (S)-nicotine increases phosphorylation ISO RGD:731712 6480464 Nicotine results in increased phosphorylation of RB1 protein CTD PMID:16862215 more ... (S)-nicotine decreases expression ISO RGD:731712 6480464 Nicotine results in decreased expression of RB1 protein CTD PMID:16011614 (Z)-3-butylidenephthalide decreases phosphorylation ISO RGD:731712 6480464 butylidenephthalide results in decreased phosphorylation of RB1 protein CTD PMID:16987298 (Z)-3-butylidenephthalide decreases phosphorylation EXP 6480464 butylidenephthalide results in decreased phosphorylation of RB1 protein CTD PMID:16987298 1,2-dimethylhydrazine multiple interactions ISO RGD:11219 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of RB1 mRNA] CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO RGD:11219 6480464 1, 2-Dimethylhydrazine results in decreased expression of RB1 mRNA CTD PMID:22206623 1,3-thiazolidine-2,4-dione decreases expression ISO RGD:731712 6480464 2, 4-thiazolidinedione results in decreased expression of RB1 protein CTD PMID:15916743 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:731712 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 17alpha-ethynylestradiol multiple interactions ISO RGD:11219 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RB1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of RB1 mRNA CTD PMID:16940010 17beta-estradiol multiple interactions ISO RGD:11219 6480464 Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]], Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein] CTD PMID:15845746 17beta-estradiol increases expression ISO RGD:731712 6480464 Estradiol results in increased expression of RB1 mRNA CTD PMID:36581016 17beta-estradiol multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [Estradiol results in increased expression of RB1 mRNA] CTD PMID:36931579 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of RB1 mRNA CTD PMID:36931579 17beta-estradiol increases phosphorylation ISO RGD:11219 6480464 Estradiol results in increased phosphorylation of RB1 protein CTD PMID:15845746 , PMID:23684557 17beta-estradiol multiple interactions ISO RGD:731712 6480464 Estradiol inhibits the reaction [E2F1 protein binds to RB1 protein modified form binds to E2F1 promoter] more ... CTD PMID:28880708 , PMID:9705214 17beta-estradiol increases phosphorylation ISO RGD:731712 6480464 Estradiol results in increased phosphorylation of RB1 protein CTD PMID:15297603 more ... 17beta-estradiol decreases expression ISO RGD:731712 6480464 Estradiol results in decreased expression of RB1 mRNA CTD PMID:19027819 17beta-hydroxy-5alpha-androstan-3-one decreases phosphorylation ISO RGD:731712 6480464 Dihydrotestosterone results in decreased phosphorylation of RB1 protein CTD PMID:15322241 17beta-hydroxy-5alpha-androstan-3-one increases phosphorylation ISO RGD:731712 6480464 Dihydrotestosterone results in increased phosphorylation of RB1 protein CTD PMID:15647840 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:731712 6480464 2 more ... CTD PMID:26988655 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:11219 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731712 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] more ... CTD PMID:15157999 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RB1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine decreases phosphorylation ISO RGD:11219 6480464 Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein CTD PMID:24013123 2,3,7,8-tetrachlorodibenzodioxine decreases phosphorylation ISO RGD:731712 6480464 Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein CTD PMID:15157999 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:11219 6480464 Tetrachlorodibenzodioxin affects the expression of RB1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of RB1 mRNA CTD PMID:21215274 , PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:11219 6480464 Tetrachlorodibenzodioxin results in increased expression of RB1 mRNA CTD PMID:12167310 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:11219 6480464 [Tetrachlorodibenzodioxin co-treated with 1 more ... CTD PMID:17942748 , PMID:20637255 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of RB1 mRNA CTD PMID:21346803 2-acetamidofluorene affects phosphorylation EXP 6480464 2-Acetylaminofluorene affects the phosphorylation of RB1 protein CTD PMID:16448463 2-acetamidofluorene multiple interactions EXP 6480464 2-Acetylaminofluorene results in increased expression of and results in increased phosphorylation of RB1 protein, RB1 protein affects the reaction [2-Acetylaminofluorene results in increased expression of PSMD10 protein] CTD PMID:15158336 , PMID:16448463 2-butoxyethanol increases expression ISO RGD:11219 6480464 n-butoxyethanol results in increased expression of RB1 mRNA CTD PMID:19812364 2-cyclopenten-1-one decreases phosphorylation ISO RGD:731712 6480464 cyclopentenone results in decreased phosphorylation of RB1 protein CTD PMID:16061222 2-methylcholine affects expression ISO RGD:731712 6480464 beta-methylcholine affects the expression of RB1 mRNA CTD PMID:21179406 2-nitrofluorene decreases expression EXP 6480464 2-nitrofluorene results in decreased expression of RB1 mRNA CTD PMID:15890375 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid multiple interactions ISO RGD:731712 6480464 MK-886 inhibits the reaction [Nicotine results in increased expression of RB1 protein modified form] CTD PMID:20061081 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione increases expression ISO RGD:731712 6480464 bisindolylmaleimide I results in increased expression of RB1 mRNA, bisindolylmaleimide I results in increased expression of RB1 protein CTD PMID:14653808 3-aminobenzamide multiple interactions ISO RGD:731712 6480464 3-aminobenzamide promotes the reaction [RB1 protein binds to E2F1 protein], 3-aminobenzamide results in decreased phosphorylation of and results in increased activity of RB1 protein CTD PMID:15670817 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:11219 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein, silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] CTD PMID:25559859 3-nitropropanoic acid decreases expression EXP 6480464 3-nitropropionic acid results in decreased expression of RB1 protein CTD PMID:21827787 4,4'-sulfonyldiphenol increases phosphorylation ISO RGD:731712 6480464 bis(4-hydroxyphenyl)sulfone results in increased phosphorylation of RB1 protein CTD PMID:30684532 4,4'-sulfonyldiphenol multiple interactions ISO RGD:731712 6480464 1 more ... CTD PMID:30684532 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:731712 6480464 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein] CTD PMID:18805435 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RB1 mRNA CTD PMID:15890375 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation ISO RGD:731712 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein CTD PMID:18805435 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid multiple interactions ISO RGD:731712 6480464 [Am 580 co-treated with Retinoids] results in decreased phosphorylation of RB1 protein CTD PMID:15383624 4-hydroxynon-2-enal decreases phosphorylation ISO RGD:731712 6480464 4-hydroxy-2-nonenal results in decreased phosphorylation of RB1 protein CTD PMID:15607904 4-hydroxynon-2-enal multiple interactions ISO RGD:11219 6480464 [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of RB1 protein modified form CTD PMID:33007382 4-hydroxyphenyl retinamide increases expression ISO RGD:731712 6480464 Fenretinide results in increased expression of RB1 protein CTD PMID:16570282 5-aza-2'-deoxycytidine decreases phosphorylation ISO RGD:731712 6480464 Decitabine results in decreased phosphorylation of RB1 protein CTD PMID:12859993 5-aza-2'-deoxycytidine affects expression ISO RGD:731712 6480464 [Decitabine affects the expression of DNMT3B protein] which affects the expression of RB1 mRNA CTD PMID:18544619 5-aza-2'-deoxycytidine decreases expression ISO RGD:731712 6480464 Decitabine results in decreased expression of RB1 mRNA CTD PMID:19027819 5-fluorouracil affects expression ISO RGD:731712 6480464 Fluorouracil affects the expression of RB1 mRNA CTD PMID:15205334 5-fluorouracil affects response to substance ISO RGD:11219 6480464 RB1 protein affects the susceptibility to Fluorouracil CTD PMID:15064736 5-fluorouracil multiple interactions ISO RGD:731712 6480464 Fluorouracil results in increased expression of and results in increased phosphorylation of RB1 protein, RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:17207318 , PMID:18678097 5-fluorouracil affects response to substance ISO RGD:731712 6480464 RB1 protein affects the susceptibility to Fluorouracil, RB1 protein modified form affects the susceptibility to Fluorouracil CTD PMID:17640669 , PMID:18383818 5-fluorouracil increases phosphorylation ISO RGD:731712 6480464 Fluorouracil results in increased phosphorylation of RB1 protein CTD PMID:9930367 5-nitroso-8-quinolinol decreases expression ISO RGD:731712 6480464 5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form CTD PMID:16497787 5-nitroso-8-quinolinol multiple interactions ISO RGD:731712 6480464 Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form] CTD PMID:16497787 6-O-methylguanine multiple interactions ISO RGD:731712 6480464 [O(6)-benzylguanine co-treated with O-(6)-methylguanine] results in increased expression of RB1 protein modified form CTD PMID:29666243 6-oxocampestanol multiple interactions ISO RGD:731712 6480464 6-oxocampestanol results in increased expression of and results in increased phosphorylation of RB1 protein CTD PMID:32001316 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of RB1 mRNA CTD PMID:24780913 7,12-dimethyltetraphene increases expression ISO RGD:11219 6480464 9 more ... CTD PMID:32553695 9-cis-retinoic acid decreases phosphorylation ISO RGD:731712 6480464 Alitretinoin results in decreased phosphorylation of RB1 protein CTD PMID:16273314 9-cis-retinoic acid multiple interactions ISO RGD:731712 6480464 Alitretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased phosphorylation of RB1 protein] CTD PMID:11348869 acetylsalicylic acid multiple interactions ISO RGD:731712 6480464 Aspirin inhibits the reaction [troglitazone results in decreased expression of RB1 protein modified form] more ... CTD PMID:19908241 acetylsalicylic acid increases expression ISO RGD:731712 6480464 Aspirin results in increased expression of RB1 protein CTD PMID:19908241 acetylsalicylic acid decreases expression ISO RGD:731712 6480464 Aspirin results in decreased expression of RB1 protein modified form CTD PMID:19908241 aconitine multiple interactions ISO RGD:731712 6480464 Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] CTD PMID:16862215 acrolein multiple interactions ISO RGD:731712 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of RB1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of RB1 mRNA CTD PMID:32699268 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of RB1 mRNA CTD PMID:28959563 Actein decreases expression ISO RGD:731712 6480464 actein results in decreased expression of RB1 protein CTD PMID:14758092 acteoside decreases phosphorylation ISO RGD:731712 6480464 acteoside results in decreased phosphorylation of RB1 protein CTD PMID:17634406 acteoside multiple interactions ISO RGD:731712 6480464 [acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein] CTD PMID:17634406 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of RB1 mRNA CTD PMID:15890375 aflatoxin B1 decreases phosphorylation ISO RGD:731712 6480464 Aflatoxin B1 results in decreased phosphorylation of RB1 protein CTD PMID:34396909 aflatoxin B1 increases methylation ISO RGD:731712 6480464 Aflatoxin B1 results in increased methylation of RB1 intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO RGD:731712 6480464 Aflatoxin B1 results in decreased methylation of RB1 gene CTD PMID:27153756 aflatoxin B1 increases expression ISO RGD:11219 6480464 Aflatoxin B1 results in increased expression of RB1 mRNA CTD PMID:19770486 aflatoxin M1 decreases expression ISO RGD:731712 6480464 Aflatoxin M1 results in decreased expression of RB1 mRNA CTD PMID:30928695 albuterol decreases expression ISO RGD:731712 6480464 Albuterol results in decreased expression of RB1 protein CTD PMID:16446544 albuterol multiple interactions ISO RGD:731712 6480464 ICI 118551 inhibits the reaction [Albuterol results in decreased expression of RB1 protein] CTD PMID:16446544 albuterol increases expression ISO RGD:731712 6480464 Albuterol results in increased expression of RB1 protein CTD PMID:18362475 aldehydo-D-glucose multiple interactions ISO RGD:731712 6480464 Fluorometholone inhibits the reaction [Glucose results in increased expression of RB1 protein] CTD PMID:35264022 aldehydo-D-glucose increases expression ISO RGD:731712 6480464 Glucose results in increased expression of RB1 protein CTD PMID:35264022 all-trans-retinoic acid multiple interactions ISO RGD:731712 6480464 [Tretinoin co-treated with TGFB1 protein] results in decreased phosphorylation of RB1 protein more ... CTD PMID:11348869 more ... all-trans-retinoic acid decreases phosphorylation ISO RGD:731712 6480464 Tretinoin results in decreased phosphorylation of RB1 protein CTD PMID:11519864 more ... all-trans-retinoic acid increases phosphorylation ISO RGD:11219 6480464 Tretinoin results in increased phosphorylation of RB1 protein CTD PMID:15949692 , PMID:16840543 all-trans-retinoic acid decreases phosphorylation ISO RGD:11219 6480464 Tretinoin results in decreased phosphorylation of RB1 protein CTD PMID:18425745 all-trans-retinoic acid decreases expression ISO RGD:11219 6480464 Tretinoin results in decreased expression of RB1 protein CTD PMID:15949692 all-trans-retinoic acid multiple interactions ISO RGD:11219 6480464 Tretinoin inhibits the reaction [RB1 protein binds to RETN promoter] CTD PMID:15047602 all-trans-retinoic acid increases phosphorylation ISO RGD:731712 6480464 Tretinoin results in increased phosphorylation of RB1 protein CTD PMID:16920920 all-trans-retinoic acid increases expression ISO RGD:731712 6480464 Tretinoin results in increased expression of RB1 mRNA, Tretinoin results in increased expression of RB1 protein CTD PMID:15194426 , PMID:15770638 all-trans-retinoic acid increases activity ISO RGD:731712 6480464 Tretinoin results in increased activity of RB1 protein CTD PMID:15194426 all-trans-retinoic acid decreases expression ISO RGD:731712 6480464 Tretinoin results in decreased expression of RB1 protein CTD PMID:12042460 alpha-hexachlorocyclohexane affects expression EXP 6480464 alpha-hexachlorocyclohexane affects the expression of RB1 mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of RB1 mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane decreases expression EXP 6480464 alpha-hexachlorocyclohexane results in decreased expression of RB1 mRNA CTD PMID:16940010 alpha-naphthoflavone multiple interactions ISO RGD:731712 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] CTD PMID:15157999 alpha-pinene multiple interactions ISO RGD:731712 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of RB1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of RB1 mRNA CTD PMID:32699268 alvocidib multiple interactions ISO RGD:731712 6480464 [docetaxel co-treated with alvocidib] results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15297405 alvocidib decreases response to substance ISO RGD:731712 6480464 RB1 results in decreased susceptibility to alvocidib CTD PMID:9829756 alvocidib decreases phosphorylation ISO RGD:731712 6480464 alvocidib results in decreased phosphorylation of RB1 protein CTD PMID:15180955 alvocidib decreases expression ISO RGD:731712 6480464 alvocidib results in decreased expression of RB1 protein, alvocidib results in decreased expression of RB1 protein modified form CTD PMID:16905211 , PMID:9829756 alvocidib decreases activity ISO RGD:731712 6480464 alvocidib results in decreased activity of RB1 protein modified form CTD PMID:10441105 amlodipine decreases phosphorylation ISO RGD:731712 6480464 Amlodipine results in decreased phosphorylation of RB1 protein CTD PMID:17217918 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RB1 mRNA CTD PMID:16483693 amodiaquine affects phosphorylation ISO RGD:731712 6480464 Amodiaquine affects the phosphorylation of RB1 protein CTD PMID:24113242 andrographolide decreases phosphorylation ISO RGD:731712 6480464 andrographolide results in decreased phosphorylation of RB1 protein CTD PMID:18619950 aniline increases phosphorylation EXP 6480464 aniline results in increased phosphorylation of RB1 protein CTD PMID:21070798 , PMID:28463034 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:731712 6480464 pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of RB1 mRNA], pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of RB1 protein] CTD PMID:14729647 antirheumatic drug decreases expression ISO RGD:731712 6480464 Antirheumatic Agents results in decreased expression of RB1 mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO RGD:731712 6480464 aristolochic acid I results in decreased expression of RB1 mRNA CTD PMID:33212167 aristolochic acid A increases expression ISO RGD:731712 6480464 aristolochic acid I results in increased expression of RB1 protein CTD PMID:33212167 arotinoid acid multiple interactions ISO RGD:731712 6480464 4-(2-(5 more ... CTD PMID:11348869 , PMID:12421932 arotinoid acid decreases phosphorylation ISO RGD:731712 6480464 4-(2-(5 more ... CTD PMID:16273314 arsenic trichloride increases phosphorylation ISO RGD:11219 6480464 arsenic trichloride results in increased phosphorylation of RB1 protein CTD PMID:16283526 arsenous acid multiple interactions ISO RGD:731712 6480464 [Arsenic Trioxide results in decreased activity of CDK6 protein] which results in decreased phosphorylation of RB1 protein more ... CTD PMID:10850458 , PMID:34042274 arsenous acid decreases expression ISO RGD:731712 6480464 Arsenic Trioxide results in decreased expression of RB1 protein modified form CTD PMID:20953137 arsenous acid decreases phosphorylation ISO RGD:731712 6480464 Arsenic Trioxide results in decreased phosphorylation of RB1 protein CTD PMID:12480548 , PMID:25335113 Aspidin increases expression ISO RGD:731712 6480464 aspidin BB results in increased expression of RB1 protein CTD PMID:23628508 atorvastatin calcium multiple interactions ISO RGD:731712 6480464 [Atorvastatin co-treated with Celecoxib] results in decreased expression of RB1 protein modified form, [Atorvastatin co-treated with Celecoxib] results in increased expression of RB1 protein CTD PMID:18172863 auranofin decreases phosphorylation ISO RGD:731712 6480464 Auranofin results in decreased phosphorylation of RB1 protein CTD PMID:20542334 baicalein decreases phosphorylation ISO RGD:731712 6480464 baicalein results in decreased phosphorylation of RB1 protein CTD PMID:22820424 baicalein multiple interactions ISO RGD:731712 6480464 AHR protein affects the reaction [baicalein results in decreased phosphorylation of RB1 protein], Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein] CTD PMID:22820424 benzene increases expression ISO RGD:731712 6480464 Benzene results in increased expression of RB1 protein, Benzene results in increased expression of RB1 protein modified form CTD PMID:20850422 benzene increases phosphorylation EXP 6480464 Benzene results in increased phosphorylation of RB1 protein CTD PMID:9118908 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RB1 mRNA, Benzo(a)pyrene results in decreased expression of RB1 protein CTD PMID:19408242 , PMID:20064080 benzo[a]pyrene affects methylation ISO RGD:731712 6480464 Benzo(a)pyrene affects the methylation of RB1 intron, Benzo(a)pyrene affects the methylation of RB1 promoter CTD PMID:27901495 , PMID:30157460 benzo[a]pyrene increases phosphorylation EXP 6480464 Benzo(a)pyrene results in increased phosphorylation of RB1 protein CTD PMID:17141280 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of RB1 protein CTD PMID:19408242 , PMID:21467743 benzo[a]pyrene decreases expression ISO RGD:11219 6480464 Benzo(a)pyrene results in decreased expression of RB1 mRNA CTD PMID:22228805 benzo[a]pyrene multiple interactions ISO RGD:11219 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RB1 mRNA] CTD PMID:22228805 benzo[a]pyrene increases expression ISO RGD:11219 6480464 Benzo(a)pyrene results in increased expression of RB1 mRNA CTD PMID:19770486 , PMID:22228805 benzo[a]pyrene multiple interactions EXP 6480464 [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA more ... CTD PMID:17141280 more ... benzo[a]pyrene increases expression ISO RGD:731712 6480464 Benzo(a)pyrene results in increased expression of RB1 mRNA more ... CTD PMID:20850422 , PMID:33411230 benzo[e]pyrene decreases methylation ISO RGD:731712 6480464 benzo(e)pyrene results in decreased methylation of RB1 intron CTD PMID:30157460 Benzo[ghi]perylene increases expression ISO RGD:731712 6480464 1, 12-benzoperylene results in increased expression of RB1 mRNA CTD PMID:35182551 benzophenanthridine decreases expression ISO RGD:731712 6480464 Benzophenanthridines analog results in decreased expression of RB1 mRNA CTD PMID:23117580 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RB1 mRNA, [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RB1 mRNA CTD PMID:18164116 betulinic acid decreases expression ISO RGD:731712 6480464 Betulinic Acid results in decreased expression of RB1 protein modified form CTD PMID:30136359 betulinic acid multiple interactions ISO RGD:731712 6480464 Betulinic Acid promotes the reaction [Erlotinib Hydrochloride results in decreased expression of RB1 protein modified form] more ... CTD PMID:30136359 bexarotene decreases phosphorylation ISO RGD:731712 6480464 bexarotene results in decreased phosphorylation of RB1 protein CTD PMID:16273314 bicalutamide increases phosphorylation ISO RGD:731712 6480464 bicalutamide results in increased phosphorylation of RB1 protein CTD PMID:17599054 bis(2-chloroethyl) sulfide increases expression ISO RGD:11219 6480464 Mustard Gas results in increased expression of RB1 mRNA CTD PMID:15674843 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:731712 6480464 Mustard Gas results in increased phosphorylation of RB1 protein CTD PMID:19845377 bisphenol A multiple interactions ISO RGD:11219 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of RB1 protein] more ... CTD PMID:21813366 bisphenol A decreases expression ISO RGD:731712 6480464 bisphenol A results in decreased expression of RB1 mRNA CTD PMID:36235125 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RB1 mRNA CTD PMID:30816183 bisphenol A affects methylation ISO RGD:11219 6480464 bisphenol A affects the methylation of RB1 promoter CTD PMID:27334623 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RB1 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:731712 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of RB1 gene more ... CTD PMID:23222814 more ... bisphenol A increases phosphorylation ISO RGD:731712 6480464 bisphenol A results in increased phosphorylation of RB1 protein CTD PMID:19654912 more ... bisphenol A decreases activity ISO RGD:731712 6480464 bisphenol A results in decreased activity of RB1 protein CTD PMID:19654912 BMS-754807 decreases phosphorylation ISO RGD:731712 6480464 BMS 754807 results in decreased phosphorylation of RB1 protein CTD PMID:24986516 BMS-754807 decreases response to substance ISO RGD:731712 6480464 RB1 mutant form results in decreased susceptibility to BMS 754807 CTD PMID:24986516 BMS-754807 multiple interactions ISO RGD:731712 6480464 BMS 754807 promotes the reaction [palbociclib results in decreased phosphorylation of RB1 protein] CTD PMID:24986516 bortezomib multiple interactions ISO RGD:731712 6480464 [Bortezomib co-treated with Butyrates] results in increased degradation of RB1 protein more ... CTD PMID:12893773 , PMID:25522274 bortezomib increases response to substance ISO RGD:731712 6480464 RB1 mutant form results in increased susceptibility to Bortezomib CTD PMID:25522274 brassinolide decreases expression ISO RGD:731712 6480464 brassinolide results in decreased expression of RB1 protein, brassinolide results in decreased expression of RB1 protein modified form CTD PMID:20833159 bucladesine decreases activity ISO RGD:731712 6480464 Bucladesine results in decreased activity of RB1 protein CTD PMID:10697531 bucladesine decreases phosphorylation EXP 6480464 Bucladesine results in decreased phosphorylation of RB1 protein CTD PMID:16718685 bucladesine multiple interactions ISO RGD:731712 6480464 Bucladesine inhibits the reaction [CASP3 protein results in increased cleavage of RB1 protein] CTD PMID:10697531 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of RB1 mRNA CTD PMID:24136188 busulfan decreases phosphorylation ISO RGD:11219 6480464 Busulfan results in decreased phosphorylation of RB1 protein CTD PMID:15388331 butyric acid multiple interactions ISO RGD:731712 6480464 [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein CTD PMID:25070040 butyric acid multiple interactions EXP 6480464 [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein CTD PMID:25070040 cadmium dichloride decreases expression ISO RGD:731712 6480464 Cadmium Chloride results in decreased expression of RB1 mRNA CTD PMID:1626475 cadmium dichloride multiple interactions ISO RGD:731712 6480464 MEG3 mRNA inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RB1 protein] CTD PMID:34520792 cadmium dichloride increases phosphorylation ISO RGD:731712 6480464 Cadmium Chloride results in increased phosphorylation of RB1 protein CTD PMID:34520792 cadmium dichloride increases expression ISO RGD:731712 6480464 Cadmium Chloride results in increased expression of RB1 mRNA CTD PMID:32512071 caffeine decreases phosphorylation ISO RGD:11219 6480464 Caffeine results in decreased phosphorylation of RB1 protein CTD PMID:15126379 caffeine affects phosphorylation ISO RGD:731712 6480464 Caffeine affects the phosphorylation of RB1 protein CTD PMID:35688186 caffeine decreases phosphorylation ISO RGD:731712 6480464 Caffeine results in decreased phosphorylation of RB1 protein CTD PMID:21229324 calciol multiple interactions ISO RGD:731712 6480464 RAF1 mutant form inhibits the reaction [Cholecalciferol results in increased expression of RB1 protein] CTD PMID:18628207 calciol increases expression ISO RGD:731712 6480464 Cholecalciferol results in increased expression of RB1 protein CTD PMID:18628207 calcitriol multiple interactions ISO RGD:731712 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of RB1 mRNA] more ... CTD PMID:14729647 , PMID:9158000 calcitriol increases expression ISO RGD:731712 6480464 Calcitriol results in increased expression of RB1 mRNA more ... CTD PMID:14729647 , PMID:9348195 calcitriol decreases phosphorylation ISO RGD:731712 6480464 Calcitriol results in decreased phosphorylation of RB1 protein, Calcitriol results in decreased phosphorylation of RB1 protein modified form CTD PMID:10825140 more ... calix[6]arene decreases phosphorylation ISO RGD:731712 6480464 calix(6)arene results in decreased phosphorylation of RB1 protein CTD PMID:23872419 calmidazolium decreases phosphorylation ISO RGD:731712 6480464 calmidazolium results in decreased phosphorylation of RB1 protein CTD PMID:12901840 , PMID:15708436 calyculin a multiple interactions ISO RGD:731712 6480464 calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] CTD PMID:12621062 camptothecin increases phosphorylation ISO RGD:731712 6480464 Camptothecin results in increased phosphorylation of RB1 protein CTD PMID:15585644 camptothecin affects response to substance ISO RGD:11219 6480464 RB1 protein affects the susceptibility to Camptothecin CTD PMID:15064736 camptothecin increases phosphorylation ISO RGD:11219 6480464 Camptothecin results in increased phosphorylation of RB1 protein CTD PMID:14647467 camptothecin affects response to substance ISO RGD:731712 6480464 RB1 protein affects the susceptibility to Camptothecin CTD PMID:14704340 canertinib multiple interactions ISO RGD:11219 6480464 Canertinib inhibits the reaction [Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein]], Canertinib inhibits the reaction [Acetaminophen results in increased phosphorylation of RB1 protein] CTD PMID:28123000 capecitabine multiple interactions ISO RGD:731712 6480464 RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 captan increases expression ISO RGD:11219 6480464 Captan results in increased expression of RB1 mRNA CTD PMID:31558096 carbamazepine affects expression ISO RGD:731712 6480464 Carbamazepine affects the expression of RB1 mRNA CTD PMID:24752500 cefaloridine affects activity EXP 6480464 Cephaloridine affects the activity of RB1 protein CTD PMID:18500788 celecoxib multiple interactions ISO RGD:731712 6480464 [Atorvastatin co-treated with Celecoxib] results in decreased expression of RB1 protein modified form, [Atorvastatin co-treated with Celecoxib] results in increased expression of RB1 protein CTD PMID:18172863 celecoxib increases expression ISO RGD:731712 6480464 Celecoxib results in increased expression of RB1 CTD PMID:19846907 CGP 52608 multiple interactions ISO RGD:731712 6480464 CGP 52608 promotes the reaction [RORA protein binds to RB1 gene] CTD PMID:28238834 Chloramine decreases phosphorylation ISO RGD:731712 6480464 chloramine results in decreased phosphorylation of RB1 protein CTD PMID:14959856 chlordecone increases expression ISO RGD:11219 6480464 Chlordecone results in increased expression of RB1 mRNA CTD PMID:33711761 chlordecone decreases expression ISO RGD:11219 6480464 Chlordecone results in decreased expression of RB1 mRNA CTD PMID:29980752 chlorohydrocarbon decreases phosphorylation ISO RGD:731712 6480464 Hydrocarbons, Chlorinated results in decreased phosphorylation of RB1 protein CTD PMID:14757120 chlorohydrocarbon decreases expression ISO RGD:731712 6480464 Hydrocarbons, Chlorinated results in decreased expression of RB1 protein CTD PMID:14757120 chlorpyrifos increases expression ISO RGD:11219 6480464 Chlorpyrifos results in increased expression of RB1 mRNA CTD PMID:37019170 chromium(6+) multiple interactions ISO RGD:731712 6480464 AKT1 protein affects the reaction [Vanadates inhibits the reaction [chromium hexavalent ion affects the localization of RB1 protein]] more ... CTD PMID:19377290 chromium(6+) affects localization ISO RGD:731712 6480464 chromium hexavalent ion affects the localization of RB1 protein CTD PMID:19377290 cisplatin affects response to substance ISO RGD:731712 6480464 RB1 protein affects the susceptibility to Cisplatin CTD PMID:14704340 , PMID:17640669 cisplatin increases expression ISO RGD:11219 6480464 Cisplatin results in increased expression of RB1 mRNA CTD PMID:21151649 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RB1 mRNA CTD PMID:17602206 colforsin daropate hydrochloride multiple interactions ISO RGD:731712 6480464 [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein] CTD PMID:9454737 copper atom affects expression ISO RGD:731712 6480464 Copper affects the expression of RB1 mRNA CTD PMID:16246896 copper atom multiple interactions ISO RGD:731712 6480464 [Chelating Agents binds to Copper] which results in increased expression of RB1 mRNA CTD PMID:30911355 copper atom increases expression ISO RGD:731712 6480464 Copper results in increased expression of RB1 mRNA CTD PMID:16391388 copper(0) affects expression ISO RGD:731712 6480464 Copper affects the expression of RB1 mRNA CTD PMID:16246896 copper(0) multiple interactions ISO RGD:731712 6480464 [Chelating Agents binds to Copper] which results in increased expression of RB1 mRNA CTD PMID:30911355 copper(0) increases expression ISO RGD:731712 6480464 Copper results in increased expression of RB1 mRNA CTD PMID:16391388 cordycepin multiple interactions ISO RGD:11219 6480464 cordycepin inhibits the reaction [FGF9 protein results in increased phosphorylation of RB1 protein] CTD PMID:33172093 coumarin decreases phosphorylation ISO RGD:731712 6480464 coumarin results in decreased phosphorylation of RB1 protein CTD PMID:35688186 crocidolite asbestos decreases phosphorylation ISO RGD:11219 6480464 Asbestos, Crocidolite results in decreased phosphorylation of RB1 protein CTD PMID:15374964 crocidolite asbestos decreases expression ISO RGD:11219 6480464 Asbestos, Crocidolite results in decreased expression of RB1 mRNA CTD PMID:29279043 crocidolite asbestos affects expression ISO RGD:731712 6480464 Asbestos, Crocidolite affects the expression of RB1 mRNA CTD PMID:17331233 crocidolite asbestos decreases expression ISO RGD:731712 6480464 Asbestos, Crocidolite results in decreased expression of RB1 protein modified form CTD PMID:21570478 cudraflavone B decreases phosphorylation ISO RGD:731712 6480464 cudraflavone B results in decreased phosphorylation of RB1 protein CTD PMID:23881456 cudraflavone B multiple interactions ISO RGD:731712 6480464 resveratrol inhibits the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein], sirtinol promotes the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] CTD PMID:23881456 cumene multiple interactions ISO RGD:11219 6480464 [cumene co-treated with KRAS gene mutant form] results in decreased expression of RB1 mRNA CTD PMID:18648096 curcumin decreases phosphorylation ISO RGD:11219 6480464 Curcumin results in decreased phosphorylation of RB1 protein CTD PMID:15738001 curcumin decreases phosphorylation ISO RGD:731712 6480464 Curcumin results in decreased phosphorylation of RB1 protein CTD PMID:18156803 , PMID:23222814 curcumin multiple interactions ISO RGD:731712 6480464 Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of RB1 protein] CTD PMID:23222814 cycloheximide multiple interactions ISO RGD:731712 6480464 RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] CTD PMID:20100483 D-glucose multiple interactions ISO RGD:731712 6480464 Fluorometholone inhibits the reaction [Glucose results in increased expression of RB1 protein] CTD PMID:35264022 D-glucose increases expression ISO RGD:731712 6480464 Glucose results in increased expression of RB1 protein CTD PMID:35264022 dactolisib decreases expression ISO RGD:731712 6480464 dactolisib results in decreased expression of RB1 protein modified form CTD PMID:23651616 daunorubicin increases expression ISO RGD:731712 6480464 Daunorubicin results in increased expression of RB1 mRNA CTD PMID:12656675 DDT increases phosphorylation ISO RGD:731712 6480464 DDT results in increased phosphorylation of RB1 protein CTD PMID:9049186 DDT increases phosphorylation ISO RGD:11219 6480464 DDT results in increased phosphorylation of RB1 protein CTD PMID:23684557 deguelin decreases expression ISO RGD:731712 6480464 deguelin results in decreased expression of RB1 protein CTD PMID:15960896 dehydroepiandrosterone increases expression EXP 6480464 Dehydroepiandrosterone results in increased expression of RB1 mRNA CTD PMID:16940010 dehydroepiandrosterone multiple interactions ISO RGD:731712 6480464 Dehydroepiandrosterone results in decreased expression of and results in decreased phosphorylation of RB1 protein CTD PMID:15752352 desferrioxamine B decreases phosphorylation ISO RGD:731712 6480464 Deferoxamine results in decreased phosphorylation of RB1 protein CTD PMID:11468187 dexamethasone increases phosphorylation ISO RGD:731712 6480464 Dexamethasone results in increased phosphorylation of RB1 protein CTD PMID:16510457 dexamethasone multiple interactions ISO RGD:11219 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein, silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] CTD PMID:25559859 dexamethasone decreases expression ISO RGD:11219 6480464 Dexamethasone results in decreased expression of RB1 mRNA CTD PMID:21041162 dexamethasone increases activity EXP 6480464 Dexamethasone results in increased activity of RB1 protein CTD PMID:19158320 dexamethasone decreases phosphorylation EXP 6480464 Dexamethasone results in decreased phosphorylation of RB1 protein CTD PMID:9442036 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [CDK2 protein results in increased phosphorylation of RB1 protein] CTD PMID:9442036 Diacetoxyscirpenol decreases expression ISO RGD:11219 6480464 diacetoxyscirpenol results in decreased expression of RB1 mRNA CTD PMID:31836554 diarsenic trioxide decreases phosphorylation ISO RGD:731712 6480464 Arsenic Trioxide results in decreased phosphorylation of RB1 protein CTD PMID:12480548 , PMID:25335113 diarsenic trioxide decreases expression ISO RGD:731712 6480464 Arsenic Trioxide results in decreased expression of RB1 protein modified form CTD PMID:20953137 diarsenic trioxide multiple interactions ISO RGD:731712 6480464 [Arsenic Trioxide results in decreased activity of CDK6 protein] which results in decreased phosphorylation of RB1 protein more ... CTD PMID:10850458 , PMID:34042274 diazinon affects expression EXP 6480464 Diazinon affects the expression of RB1 mRNA CTD PMID:22546817 dibutyl phthalate increases phosphorylation EXP 6480464 Dibutyl Phthalate results in increased phosphorylation of RB1 protein CTD PMID:16916955 diclofenac affects expression ISO RGD:731712 6480464 Diclofenac affects the expression of RB1 mRNA CTD PMID:24752500 dicoumarol increases phosphorylation ISO RGD:731712 6480464 Dicumarol results in increased phosphorylation of RB1 protein CTD PMID:15896341 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of RB1 mRNA CTD PMID:22546817 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of RB1 mRNA CTD PMID:15890375 diethylstilbestrol increases expression ISO RGD:11219 6480464 Diethylstilbestrol results in increased expression of RB1 mRNA CTD PMID:15545218 dioxygen increases expression ISO RGD:11219 6480464 Oxygen deficiency results in increased expression of RB1 mRNA CTD PMID:22629407 dioxygen multiple interactions ISO RGD:11219 6480464 Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of RB1 mRNA] CTD PMID:22629407 doxazosin affects phosphorylation EXP 6480464 Doxazosin affects the phosphorylation of RB1 protein CTD PMID:18084315 doxazosin decreases phosphorylation ISO RGD:731712 6480464 Doxazosin results in decreased phosphorylation of RB1 protein CTD PMID:15371785 doxorubicin affects expression ISO RGD:731712 6480464 Doxorubicin affects the expression of RB1 mRNA CTD PMID:15205334 doxorubicin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [Doxorubicin results in decreased expression of RB1 protein] CTD PMID:33484087 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of RB1 protein CTD PMID:33484087 doxorubicin decreases phosphorylation ISO RGD:731712 6480464 Doxorubicin results in decreased phosphorylation of RB1 protein CTD PMID:15141020 , PMID:22927544 doxorubicin multiple interactions ISO RGD:731712 6480464 Acetylcysteine inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein] more ... CTD PMID:16537896 more ... ellagic acid multiple interactions EXP 6480464 Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA], Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 emodin decreases expression ISO RGD:731712 6480464 Emodin results in decreased expression of RB1 mRNA CTD PMID:16045814 endosulfan decreases phosphorylation ISO RGD:731712 6480464 Endosulfan results in decreased phosphorylation of RB1 protein CTD PMID:26714676 erlotinib hydrochloride decreases phosphorylation ISO RGD:11219 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of RB1 protein CTD PMID:21195724 erlotinib hydrochloride multiple interactions ISO RGD:731712 6480464 Betulinic Acid promotes the reaction [Erlotinib Hydrochloride results in decreased expression of RB1 protein modified form], Erlotinib Hydrochloride promotes the reaction [Betulinic Acid results in decreased expression of RB1 protein modified form] CTD PMID:30136359 erlotinib hydrochloride decreases expression ISO RGD:731712 6480464 Erlotinib Hydrochloride results in decreased expression of RB1 protein modified form CTD PMID:30136359 ethanol affects expression EXP 6480464 Ethanol affects the expression of RB1 mRNA CTD PMID:11772933 ethanol affects expression ISO RGD:11219 6480464 Ethanol affects the expression of RB1 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:731712 6480464 Ethyl Methanesulfonate results in increased expression of RB1 mRNA CTD PMID:23649840 ethyl trans-caffeate affects phosphorylation ISO RGD:731712 6480464 ethyl caffeate affects the phosphorylation of RB1 protein CTD PMID:24892518 etoposide affects response to substance ISO RGD:731712 6480464 RB1 protein affects the susceptibility to Etoposide CTD PMID:17640669 etoposide decreases phosphorylation ISO RGD:731712 6480464 Etoposide results in decreased phosphorylation of RB1 protein CTD PMID:9454737 etoposide multiple interactions ISO RGD:731712 6480464 [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein] CTD PMID:9454737 eugenol decreases expression ISO RGD:731712 6480464 Eugenol results in decreased expression of RB1 protein CTD PMID:22686307 everolimus multiple interactions ISO RGD:731712 6480464 [letrozole co-treated with Everolimus] results in decreased phosphorylation of and affects the activity of RB1 protein, Everolimus results in decreased phosphorylation of and affects the activity of RB1 protein CTD PMID:16033851 everolimus decreases phosphorylation ISO RGD:731712 6480464 Everolimus results in decreased phosphorylation of RB1 protein CTD PMID:16856892 farrerol decreases phosphorylation ISO RGD:731712 6480464 farrerol results in decreased phosphorylation of RB1 protein CTD PMID:35833306 fenhexamid increases expression ISO RGD:731712 6480464 N-(2, 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of RB1 mRNA CTD PMID:25461557 fenhexamid multiple interactions ISO RGD:731712 6480464 [systhane co-treated with N-(2, 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] affects the expression of RB1 mRNA CTD PMID:25461557 ferulic acid decreases phosphorylation EXP 6480464 ferulic acid results in decreased phosphorylation of RB1 protein CTD PMID:15363954 ferulic acid decreases phosphorylation ISO RGD:731712 6480464 ferulic acid results in decreased phosphorylation of RB1 protein CTD PMID:15486966 flavanone decreases phosphorylation ISO RGD:731712 6480464 flavanone results in decreased phosphorylation of RB1 protein CTD PMID:22056764 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of RB1 mRNA CTD PMID:18035473 fluorometholone multiple interactions ISO RGD:731712 6480464 Fluorometholone inhibits the reaction [Glucose results in increased expression of RB1 protein] CTD PMID:35264022 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of RB1 mRNA CTD PMID:24136188 fluvastatin decreases phosphorylation ISO RGD:731712 6480464 fluvastatin results in decreased phosphorylation of RB1 protein CTD PMID:16996129 folic acid multiple interactions ISO RGD:11219 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of RB1 mRNA] CTD PMID:22206623 folpet increases expression ISO RGD:11219 6480464 folpet results in increased expression of RB1 mRNA CTD PMID:31558096 fucoidan decreases expression ISO RGD:731712 6480464 fucoidan results in decreased expression of RB1 protein CTD PMID:16201850 fulvestrant multiple interactions ISO RGD:731712 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of RB1 gene more ... CTD PMID:21367843 more ... fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [Estradiol results in increased expression of RB1 mRNA] CTD PMID:36931579 fulvestrant decreases phosphorylation ISO RGD:731712 6480464 fulvestrant results in decreased phosphorylation of RB1 protein CTD PMID:21367843 furan decreases expression EXP 6480464 furan results in decreased expression of RB1 mRNA CTD PMID:26194646 gadolinium trichloride increases phosphorylation ISO RGD:731712 6480464 gadolinium chloride results in increased phosphorylation of RB1 protein CTD PMID:19184457 galangin decreases phosphorylation ISO RGD:731712 6480464 galangin results in decreased phosphorylation of RB1 protein CTD PMID:25450235 gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of RB1 mRNA CTD PMID:17785943 gamma-tocopherol decreases phosphorylation ISO RGD:731712 6480464 Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 gefitinib decreases expression ISO RGD:731712 6480464 Gefitinib results in decreased expression of RB1 protein modified form CTD PMID:30136359 gefitinib multiple interactions ISO RGD:731712 6480464 Betulinic Acid promotes the reaction [Gefitinib results in decreased expression of RB1 protein modified form], Gefitinib promotes the reaction [Betulinic Acid results in decreased expression of RB1 protein modified form] CTD PMID:30136359 genistein multiple interactions ISO RGD:731712 6480464 Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein, lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein] CTD PMID:17051425 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of RB1 mRNA CTD PMID:22061828 gingerol decreases phosphorylation ISO RGD:731712 6480464 gingerol results in decreased phosphorylation of RB1 protein CTD PMID:18058799 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of RB1 mRNA CTD PMID:24136188 glucose multiple interactions ISO RGD:731712 6480464 Fluorometholone inhibits the reaction [Glucose results in increased expression of RB1 protein] CTD PMID:35264022 glucose increases expression ISO RGD:731712 6480464 Glucose results in increased expression of RB1 protein CTD PMID:35264022 glutathione multiple interactions ISO RGD:731712 6480464 Glutathione inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein], Glutathione inhibits the reaction [Levamisole results in decreased expression of RB1 protein] CTD PMID:11139434 , PMID:22927544 GW 4064 increases phosphorylation ISO RGD:731712 6480464 GW 4064 results in increased phosphorylation of RB1 protein CTD PMID:31437187 heparin multiple interactions ISO RGD:731712 6480464 Heparin analog results in decreased expression of and results in decreased phosphorylation of RB1 protein CTD PMID:20201787 heptachlor decreases expression ISO RGD:731712 6480464 Heptachlor results in decreased expression of RB1 protein CTD PMID:10048758 hydrogen peroxide multiple interactions ISO RGD:731712 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RB1 protein more ... CTD PMID:12621062 more ... hydrogen peroxide decreases phosphorylation ISO RGD:731712 6480464 Hydrogen Peroxide results in decreased phosphorylation of RB1 protein CTD PMID:12621062 , PMID:15242773 hydrogen peroxide decreases expression ISO RGD:731712 6480464 Hydrogen Peroxide results in decreased expression of RB1 mRNA CTD PMID:12419474 hydroquinone increases expression ISO RGD:731712 6480464 hydroquinone results in increased expression of RB protein CTD PMID:26047893 hydroquinone multiple interactions ISO RGD:731712 6480464 [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein more ... CTD PMID:30506647 more ... hydroquinone decreases expression ISO RGD:731712 6480464 hydroquinone results in decreased expression of RB1 mRNA, hydroquinone results in decreased expression of RB1 protein CTD PMID:33771647 , PMID:33932074 hydroxyurea increases expression ISO RGD:11219 6480464 Hydroxyurea results in increased expression of RB1 mRNA CTD PMID:27208086 , PMID:29228353 hydroxyurea multiple interactions ISO RGD:11219 6480464 TRP53 gene mutant form inhibits the reaction [Hydroxyurea results in increased expression of RB1 mRNA] CTD PMID:29228353 ibuprofen decreases phosphorylation EXP 6480464 Ibuprofen results in decreased phosphorylation of RB1 protein CTD PMID:15099639 ICI 118551 multiple interactions ISO RGD:731712 6480464 ICI 118551 inhibits the reaction [Albuterol results in decreased expression of RB1 protein] CTD PMID:16446544 indirubin multiple interactions ISO RGD:731712 6480464 indirubin inhibits the reaction [CDK2 protein results in increased phosphorylation of RB1 protein] CTD PMID:16115123 indirubin multiple interactions ISO RGD:11219 6480464 [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein more ... CTD PMID:18344322 indoles decreases phosphorylation ISO RGD:731712 6480464 Indoles analog results in decreased phosphorylation of RB1 protein CTD PMID:15149644 indometacin multiple interactions EXP 6480464 Indomethacin inhibits the reaction [FGF2 protein results in increased phosphorylation of RB1 protein] CTD PMID:11170841 indometacin decreases phosphorylation ISO RGD:731712 6480464 Indomethacin results in decreased phosphorylation of RB1 protein CTD PMID:18791128 inulin multiple interactions ISO RGD:11219 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of RB1 mRNA CTD PMID:36331819 irinotecan affects expression ISO RGD:731712 6480464 Irinotecan affects the expression of RB1 protein CTD PMID:15132777 isocyanates increases expression ISO RGD:11219 6480464 Isocyanates results in increased expression of RB1 protein CTD PMID:20685613 isoeugenol decreases expression ISO RGD:731712 6480464 isoeugenol results in decreased expression of RB1 protein CTD PMID:22686307 ivermectin decreases expression ISO RGD:731712 6480464 Ivermectin results in decreased expression of RB1 protein CTD PMID:32959892 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of RB1 mRNA CTD PMID:20080153 KN-93 decreases phosphorylation ISO RGD:731712 6480464 KN 93 results in decreased phosphorylation of RB1 protein CTD PMID:15958590 L-cysteine decreases phosphorylation ISO RGD:731712 6480464 Cysteine analog results in decreased phosphorylation of RB1 protein CTD PMID:15890017 lapatinib multiple interactions ISO RGD:731712 6480464 Lapatinib inhibits the reaction [sodium arsenite results in decreased phosphorylation of RB1 protein] CTD PMID:32890875 lead nitrate increases expression ISO RGD:731712 6480464 lead nitrate results in increased expression of RB1 mRNA CTD PMID:24639330 lead nitrate multiple interactions ISO RGD:731712 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:24639330 lead(0) affects expression ISO RGD:731712 6480464 Lead affects the expression of RB1 mRNA CTD PMID:28903495 letrozole multiple interactions ISO RGD:731712 6480464 [letrozole co-treated with Everolimus] results in decreased phosphorylation of and affects the activity of RB1 protein more ... CTD PMID:16033851 , PMID:20054642 levamisole multiple interactions ISO RGD:731712 6480464 Acetylcysteine inhibits the reaction [Levamisole results in decreased expression of RB1 protein], Glutathione inhibits the reaction [Levamisole results in decreased expression of RB1 protein] CTD PMID:11139434 levamisole decreases expression ISO RGD:731712 6480464 Levamisole results in decreased expression of RB1 protein CTD PMID:11139434 linsidomine decreases phosphorylation ISO RGD:11219 6480464 linsidomine results in decreased phosphorylation of RB1 protein CTD PMID:12600834 lipopolysaccharide decreases expression ISO RGD:11219 6480464 Lipopolysaccharides results in decreased expression of RB1 mRNA CTD PMID:12057914 lithium chloride multiple interactions ISO RGD:11219 6480464 Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]] CTD PMID:15845746 lithium chloride multiple interactions ISO RGD:731712 6480464 Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein] CTD PMID:22820424 lonafarnib multiple interactions ISO RGD:11219 6480464 lonafarnib results in decreased phosphorylation of and results in decreased activity of RB1 protein CTD PMID:12673674 lopinavir affects phosphorylation ISO RGD:731712 6480464 Lopinavir affects the phosphorylation of RB1 protein CTD PMID:20596751 lovastatin decreases phosphorylation EXP 6480464 Lovastatin results in decreased phosphorylation of RB1 protein CTD PMID:9848777 lovastatin decreases phosphorylation ISO RGD:731712 6480464 Lovastatin results in decreased phosphorylation of RB1 protein CTD PMID:10502407 , PMID:15118409 LY294002 multiple interactions ISO RGD:11219 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vanadates results in increased phosphorylation of RB1 protein] CTD PMID:14971663 LY294002 decreases phosphorylation ISO RGD:11219 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RB1 protein CTD PMID:15601625 LY294002 multiple interactions ISO RGD:731712 6480464 [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased phosphorylation of RB1 protein] CTD PMID:15778701 lycopene multiple interactions ISO RGD:731712 6480464 lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein], lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] CTD PMID:16565789 , PMID:17051425 lycopene decreases phosphorylation ISO RGD:731712 6480464 lycopene results in decreased phosphorylation of RB1 protein CTD PMID:17337101 magnesium atom multiple interactions EXP 6480464 1 more ... CTD PMID:30542433 magnesium atom decreases phosphorylation EXP 6480464 Magnesium deficiency results in decreased phosphorylation of RB1 protein CTD PMID:30542433 maneb increases expression EXP 6480464 Maneb results in increased expression of RB1 mRNA CTD PMID:29859004 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA more ... CTD PMID:29859004 masoprocol decreases phosphorylation ISO RGD:731712 6480464 Masoprocol results in decreased phosphorylation of RB1 protein CTD PMID:18164318 Maxacalcitol decreases phosphorylation ISO RGD:731712 6480464 maxacalcitol results in decreased phosphorylation of RB1 protein CTD PMID:16039115 menadione increases expression ISO RGD:731712 6480464 Vitamin K 3 results in increased expression of RB1 mRNA CTD PMID:16010434 menaquinone increases expression ISO RGD:731712 6480464 Vitamin K 2 results in increased expression of RB1 mRNA CTD PMID:16010434 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of RB1 mRNA CTD PMID:15890375 methapyrilene decreases methylation ISO RGD:731712 6480464 Methapyrilene results in decreased methylation of RB1 intron CTD PMID:30157460 methotrexate affects response to substance ISO RGD:731712 6480464 RB1 gene affects the susceptibility to Methotrexate, RB1 protein affects the susceptibility to Methotrexate CTD PMID:12972956 , PMID:14679136 methotrexate multiple interactions ISO RGD:731712 6480464 Methotrexate inhibits the reaction [RB1 protein binds to E2F1 protein] CTD PMID:22484375 methotrexate increases phosphorylation ISO RGD:11219 6480464 Methotrexate results in increased phosphorylation of RB1 protein CTD PMID:22484375 methotrexate increases phosphorylation ISO RGD:731712 6480464 Methotrexate results in increased phosphorylation of RB1 protein CTD PMID:22484375 methotrexate increases response to substance ISO RGD:731712 6480464 RB1 protein results in increased susceptibility to Methotrexate CTD PMID:14534726 methoxsalen multiple interactions ISO RGD:731712 6480464 Methoxsalen inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] CTD PMID:15157999 methoxyacetic acid multiple interactions ISO RGD:731712 6480464 withanone inhibits the reaction [methoxyacetic acid results in increased phosphorylation of RB1 protein] CTD PMID:21573189 methoxyacetic acid increases phosphorylation ISO RGD:731712 6480464 methoxyacetic acid results in increased phosphorylation of RB1 protein CTD PMID:21573189 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of RB1 gene CTD PMID:35440735 methyl methanesulfonate increases expression ISO RGD:731712 6480464 Methyl Methanesulfonate results in increased expression of RB1 mRNA CTD PMID:23649840 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of RB1 mRNA CTD PMID:28526320 methylseleninic acid multiple interactions ISO RGD:731712 6480464 methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein], methylselenic acid results in decreased phosphorylation of and results in increased expression of RB1 protein CTD PMID:17847021 miconazole decreases expression ISO RGD:11219 6480464 Miconazole results in decreased expression of RB1 mRNA CTD PMID:27462272 mifepristone increases activity ISO RGD:731712 6480464 Mifepristone results in increased activity of RB1 protein CTD PMID:15297425 mitomycin C decreases expression ISO RGD:731712 6480464 Mitomycin results in decreased expression of RB1 protein modified form CTD PMID:15617745 monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of RB1 mRNA CTD PMID:28954212 monosodium L-glutamate increases phosphorylation EXP 6480464 Sodium Glutamate results in increased phosphorylation of RB1 protein CTD PMID:28954212 motexafin gadolinium decreases expression ISO RGD:731712 6480464 motexafin gadolinium results in decreased expression of RB1 mRNA CTD PMID:16357179 motexafin gadolinium multiple interactions ISO RGD:731712 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA CTD PMID:16357179 myo-inositol hexakisphosphate decreases phosphorylation ISO RGD:731712 6480464 Phytic Acid results in decreased phosphorylation of RB1 protein CTD PMID:15868430 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:731712 6480464 N more ... CTD PMID:18778698 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:731712 6480464 TP53 mutant form inhibits the reaction [N more ... CTD PMID:18778698 N-(6-acetamidohexyl)acetamide decreases phosphorylation ISO RGD:731712 6480464 hexamethylene bisacetamide results in decreased phosphorylation of RB1 protein CTD PMID:10597302 N-acetyl-L-cysteine multiple interactions ISO RGD:731712 6480464 Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form] more ... CTD PMID:11139434 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA] more ... CTD PMID:29859004 N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of RB1 mRNA CTD PMID:15954086 N-methyl-4-phenylpyridinium decreases phosphorylation ISO RGD:731712 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RB1 protein CTD PMID:15247282 N-methyl-N-nitrosourea increases phosphorylation EXP 6480464 Methylnitrosourea results in increased phosphorylation of RB1 protein CTD PMID:15581186 N-nitrosodiethylamine multiple interactions ISO RGD:11219 6480464 RB1 protein affects the reaction [Diethylnitrosamine results in increased expression of RBL1 protein] more ... CTD PMID:17854601 more ... N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of RB1 protein CTD PMID:19822196 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of RB1 mRNA CTD PMID:19638242 N-nitrosodiethylamine decreases response to substance ISO RGD:11219 6480464 RB1 protein results in decreased susceptibility to Diethylnitrosamine CTD PMID:17854601 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RB1 mRNA more ... CTD PMID:17602206 , PMID:18164116 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of RB1 mRNA CTD PMID:15890375 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of RB1 mRNA CTD PMID:24136188 nelfinavir decreases phosphorylation ISO RGD:731712 6480464 Nelfinavir results in decreased phosphorylation of RB protein CTD PMID:17283158 nickel atom decreases expression ISO RGD:731712 6480464 Nickel results in decreased expression of RB1 mRNA CTD PMID:23195993 nickel dichloride decreases expression ISO RGD:731712 6480464 nickel chloride results in decreased expression of RB1 protein CTD PMID:21837363 nicotine multiple interactions ISO RGD:731712 6480464 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in increased phosphorylation of RB1 protein] more ... CTD PMID:16601104 more ... nicotine increases phosphorylation ISO RGD:11219 6480464 Nicotine results in increased phosphorylation of RB1 protein CTD PMID:15574422 nicotine increases expression ISO RGD:731712 6480464 Nicotine results in increased expression of RB1 protein modified form CTD PMID:20061081 nicotine increases phosphorylation ISO RGD:731712 6480464 Nicotine results in increased phosphorylation of RB1 protein CTD PMID:16862215 more ... nicotine decreases expression ISO RGD:731712 6480464 Nicotine results in decreased expression of RB1 protein CTD PMID:16011614 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of RB1 mRNA CTD PMID:24136188 nitrogen dioxide decreases phosphorylation ISO RGD:11219 6480464 Nitrogen Dioxide results in decreased phosphorylation of RB1 protein CTD PMID:12600834 Nonylphenol increases phosphorylation ISO RGD:731712 6480464 nonylphenol results in increased phosphorylation of RB1 protein CTD PMID:33516137 O-(chloroacetylcarbamoyl)fumagillol decreases phosphorylation ISO RGD:731712 6480464 O-(chloroacetylcarbamoyl)fumagillol results in decreased phosphorylation of RB1 protein CTD PMID:15276080 O-methyleugenol decreases expression EXP 6480464 methyleugenol results in decreased expression of RB1 mRNA CTD PMID:26011634 ochratoxin A multiple interactions ISO RGD:731712 6480464 ochratoxin A affects the expression of and affects the phosphorylation of RB1 protein CTD PMID:28286205 okadaic acid multiple interactions ISO RGD:731712 6480464 Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] CTD PMID:12621062 oleic acid decreases phosphorylation ISO RGD:731712 6480464 Oleic Acid results in decreased phosphorylation of RB1 protein CTD PMID:16027227 olomoucine increases expression ISO RGD:731712 6480464 olomoucine results in increased expression of RB1 mRNA, olomoucine results in increased expression of RB1 protein CTD PMID:14653808 orlistat decreases phosphorylation ISO RGD:731712 6480464 orlistat results in decreased phosphorylation of RB1 protein CTD PMID:15138278 oxaliplatin decreases phosphorylation ISO RGD:731712 6480464 oxaliplatin results in decreased phosphorylation of RB1 protein CTD PMID:15204521 , PMID:16227409 oxaliplatin increases phosphorylation ISO RGD:731712 6480464 oxaliplatin results in increased phosphorylation of RB1 protein CTD PMID:15204521 oxybenzone increases expression ISO RGD:731712 6480464 oxybenzone results in increased expression of RB1 mRNA CTD PMID:36581016 ozone multiple interactions ISO RGD:731712 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of RB1 mRNA more ... CTD PMID:32699268 ozone decreases expression ISO RGD:731712 6480464 Ozone results in decreased expression of RB1 mRNA CTD PMID:23033980 p-menthan-3-ol increases expression ISO RGD:731712 6480464 Menthol results in increased expression of RB1 mRNA CTD PMID:26760959 paclitaxel multiple interactions ISO RGD:731712 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Paclitaxel results in increased phosphorylation of RB1 protein] CTD PMID:15138593 paclitaxel increases phosphorylation ISO RGD:731712 6480464 Paclitaxel results in increased phosphorylation of RB1 protein CTD PMID:15138593 palbociclib multiple interactions ISO RGD:731712 6480464 BMS 754807 promotes the reaction [palbociclib results in decreased phosphorylation of RB1 protein] more ... CTD PMID:20100483 more ... palbociclib decreases expression ISO RGD:731712 6480464 palbociclib results in decreased expression of RB1 mRNA, palbociclib results in decreased expression of RB1 protein CTD PMID:26318986 palbociclib decreases response to substance ISO RGD:731712 6480464 RB1 gene mutant form results in decreased susceptibility to palbociclib, RB1 mutant form results in decreased susceptibility to palbociclib CTD PMID:21278246 , PMID:24986516 palbociclib affects phosphorylation ISO RGD:731712 6480464 palbociclib affects the phosphorylation of RB1 protein CTD PMID:21880723 palbociclib affects reaction ISO RGD:731712 6480464 RB1 protein affects the reaction palbociclib CTD PMID:25221644 palbociclib increases phosphorylation ISO RGD:731712 6480464 palbociclib results in increased phosphorylation of RB1 protein CTD PMID:23138228 palbociclib decreases phosphorylation ISO RGD:731712 6480464 palbociclib results in decreased phosphorylation of RB1 protein CTD PMID:15542782 more ... palbociclib increases response to substance ISO RGD:731712 6480464 RB1 protein results in increased susceptibility to palbociclib CTD PMID:21278246 , PMID:23708653 palbociclib multiple interactions ISO RGD:11219 6480464 [CDKN2A gene mutant form results in increased susceptibility to palbociclib] which results in decreased phosphorylation of RB1 protein CTD PMID:24098593 palbociclib affects response to substance ISO RGD:731712 6480464 RB1 protein affects the susceptibility to palbociclib CTD PMID:20354191 more ... panaxydol increases expression ISO RGD:731712 6480464 panaxydol results in increased expression of RB1 protein, panaxydol results in increased expression of RB1 protein modified form CTD PMID:19450571 paracetamol increases expression ISO RGD:731712 6480464 Acetaminophen results in increased expression of RB1 mRNA CTD PMID:22230336 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of RB1 mRNA CTD PMID:33387578 paracetamol multiple interactions ISO RGD:11219 6480464 Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein] more ... CTD PMID:28123000 , PMID:34546377 paracetamol increases phosphorylation ISO RGD:11219 6480464 Acetaminophen results in increased phosphorylation of RB1 protein CTD PMID:28123000 paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA more ... CTD PMID:29859004 paraquat increases expression EXP 6480464 Paraquat results in increased expression of RB1 mRNA CTD PMID:29859004 paraquat increases expression ISO RGD:11219 6480464 Paraquat results in increased expression of RB1 mRNA CTD PMID:28012437 pentachlorophenol increases phosphorylation EXP 6480464 Pentachlorophenol results in increased phosphorylation of RB1 protein CTD PMID:19442831 pentobarbital decreases expression EXP 6480464 Pentobarbital results in decreased expression of RB1 protein modified form CTD PMID:19346066 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:11219 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of RB1 mRNA, [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of RB1 mRNA CTD PMID:36331819 perfluorooctanoic acid decreases expression ISO RGD:731712 6480464 perfluorooctanoic acid results in decreased expression of RB1 protein CTD PMID:26879310 phenethyl caffeate decreases expression EXP 6480464 caffeic acid phenethyl ester results in decreased expression of RB1 protein modified form CTD PMID:15885897 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of RB1 mRNA CTD PMID:16940010 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of RB1 protein CTD PMID:15603588 phenylephrine affects phosphorylation EXP 6480464 Phenylephrine affects the phosphorylation of RB1 protein CTD PMID:18084315 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of RB1 protein modified form CTD PMID:14522882 PhIP decreases phosphorylation ISO RGD:731712 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased phosphorylation of RB1 protein CTD PMID:15635149 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731712 6480464 4-(2-(5 more ... CTD PMID:12421932 , PMID:16979875 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:731712 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein CTD PMID:12421932 , PMID:8927716 phorbol 13-acetate 12-myristate increases expression ISO RGD:731712 6480464 Tetradecanoylphorbol Acetate results in increased expression of RB1 protein modified form CTD PMID:9348195 phorbol 13-acetate 12-myristate decreases phosphorylation ISO RGD:731712 6480464 Tetradecanoylphorbol Acetate results in decreased phosphorylation of RB1 protein CTD PMID:15978937 phosalone multiple interactions EXP 6480464 Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA], Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 phosalone increases expression EXP 6480464 phosalone results in increased expression of RB1 mRNA, phosalone results in increased expression of RB1 protein CTD PMID:27965107 picoxystrobin increases expression ISO RGD:731712 6480464 picoxystrobin results in increased expression of RB1 mRNA CTD PMID:33512557 pinosylvin decreases expression ISO RGD:731712 6480464 pinosylvin results in decreased expression of RB1 protein CTD PMID:23333577 pioglitazone multiple interactions ISO RGD:731712 6480464 pioglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 piperonyl butoxide decreases expression EXP 6480464 Piperonyl Butoxide results in decreased expression of RB1 mRNA CTD PMID:15890375 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of RB1 mRNA CTD PMID:16940010 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of RB1 mRNA CTD PMID:15890375 piroxicam decreases expression ISO RGD:731712 6480464 Piroxicam results in decreased expression of RB1 mRNA CTD PMID:21858171 prednisone multiple interactions ISO RGD:731712 6480464 Prednisone results in decreased phosphorylation of and results in decreased activity of RB1 protein CTD PMID:15034294 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [Doxorubicin results in decreased expression of RB1 protein] CTD PMID:33484087 proanthocyanidin increases expression EXP 6480464 Proanthocyanidins results in increased expression of RB1 protein CTD PMID:33484087 procyanidin multiple interactions ISO RGD:731712 6480464 procyanidin results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15827326 progesterone multiple interactions ISO RGD:11219 6480464 Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]], Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein] CTD PMID:15845746 promethazine decreases expression EXP 6480464 Promethazine results in decreased expression of RB1 mRNA CTD PMID:26011634 pterostilbene decreases expression EXP 6480464 pterostilbene results in decreased expression of RB1 protein CTD PMID:20398797 PX-866 multiple interactions ISO RGD:731712 6480464 [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of RB1 protein CTD PMID:26660119 quercetin affects expression ISO RGD:731712 6480464 Quercetin affects the expression of RB1 protein modified form CTD PMID:14767529 quercetin multiple interactions ISO RGD:731712 6480464 [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein, Quercetin inhibits the reaction [IL6 protein results in increased phosphorylation of RB1 protein] CTD PMID:22394507 , PMID:25070040 quercetin multiple interactions EXP 6480464 [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein CTD PMID:25070040 quercetin decreases phosphorylation ISO RGD:731712 6480464 Quercetin results in decreased phosphorylation of RB1 protein CTD PMID:16049707 more ... quercetin increases expression ISO RGD:731712 6480464 Quercetin results in increased expression of RB1 mRNA CTD PMID:14715546 radicicol affects phosphorylation ISO RGD:731712 6480464 monorden affects the phosphorylation of RB1 protein CTD PMID:21880723 raloxifene decreases expression ISO RGD:731712 6480464 Raloxifene Hydrochloride results in decreased expression of RB1 mRNA CTD PMID:19429434 raloxifene multiple interactions ISO RGD:731712 6480464 [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of RB1 protein CTD PMID:26660119 resveratrol multiple interactions ISO RGD:731712 6480464 [temozolomide co-treated with resveratrol] results in increased phosphorylation of RB1 protein, resveratrol inhibits the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] CTD PMID:23522185 , PMID:23881456 resveratrol decreases phosphorylation ISO RGD:11219 6480464 resveratrol results in decreased phosphorylation of RB1 protein CTD PMID:23525482 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of RB1 protein modified form CTD PMID:22104698 resveratrol decreases phosphorylation ISO RGD:731712 6480464 resveratrol results in decreased phosphorylation of RB1 protein CTD PMID:11481417 more ... resveratrol affects expression ISO RGD:11219 6480464 resveratrol affects the expression of RB1 mRNA, resveratrol affects the expression of RB1 protein CTD PMID:16369916 ritonavir decreases phosphorylation ISO RGD:731712 6480464 Ritonavir results in decreased phosphorylation of RB1 protein CTD PMID:16551874 more ... ritonavir increases expression ISO RGD:731712 6480464 Ritonavir results in increased expression of RB1 mRNA CTD PMID:19386116 Ro 41-5253 multiple interactions ISO RGD:731712 6480464 Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]] CTD PMID:12421932 romidepsin decreases phosphorylation ISO RGD:731712 6480464 romidepsin results in decreased phosphorylation of RB1 protein CTD PMID:15014036 , PMID:15849726 rottlerin decreases phosphorylation ISO RGD:731712 6480464 rottlerin results in decreased phosphorylation of RB1 protein CTD PMID:15949478 S-(1,2-dichlorovinyl)-L-cysteine increases phosphorylation ISO RGD:11219 6480464 S-(1, 2-dichlorovinyl)cysteine results in increased phosphorylation of RB1 protein CTD PMID:16495211 SB 203580 multiple interactions ISO RGD:731712 6480464 SB 203580 inhibits the reaction [FGF2 protein results in increased phosphorylation of RB1 protein] CTD PMID:15249425 silibinin multiple interactions ISO RGD:11219 6480464 Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] CTD PMID:25559859 simvastatin decreases phosphorylation ISO RGD:731712 6480464 Simvastatin results in decreased phosphorylation of RB1 protein CTD PMID:17928568 simvastatin decreases phosphorylation EXP 6480464 Simvastatin results in decreased phosphorylation of RB1 protein CTD PMID:18804536 sirolimus multiple interactions ISO RGD:731712 6480464 [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased phosphorylation of RB1 protein] more ... CTD PMID:10373522 more ... sirolimus decreases phosphorylation ISO RGD:731712 6480464 Sirolimus results in decreased phosphorylation of RB1 protein CTD PMID:12393642 more ... sirolimus decreases phosphorylation EXP 6480464 Sirolimus results in decreased phosphorylation of RB1 protein CTD PMID:7532117 sirolimus multiple interactions ISO RGD:11219 6480464 [Sirolimus co-treated with TGFB1 protein] results in decreased phosphorylation of RB1 protein more ... CTD PMID:10849422 more ... sirtinol multiple interactions ISO RGD:731712 6480464 sirtinol promotes the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] CTD PMID:23881456 sodium arsenite multiple interactions ISO RGD:731712 6480464 JUN protein promotes the reaction [sodium arsenite results in increased phosphorylation of RB1 protein] more ... CTD PMID:21726611 more ... sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of RB1 mRNA CTD PMID:35314868 sodium arsenite decreases phosphorylation ISO RGD:731712 6480464 sodium arsenite results in decreased phosphorylation of RB1 protein CTD PMID:32890875 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of RB1 mRNA CTD PMID:11241755 sodium arsenite increases phosphorylation ISO RGD:11219 6480464 sodium arsenite results in increased phosphorylation of RB1 protein CTD PMID:11807808 sodium arsenite increases expression ISO RGD:11219 6480464 sodium arsenite results in increased expression of RB1 mRNA CTD PMID:19822182 sodium arsenite increases phosphorylation ISO RGD:731712 6480464 sodium arsenite results in increased phosphorylation of RB1 protein CTD PMID:21726611 sodium arsenite increases expression ISO RGD:731712 6480464 sodium arsenite results in increased expression of RB1 mRNA CTD PMID:17879257 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of RB1 mRNA CTD PMID:25993096 sodium dichromate increases expression ISO RGD:11219 6480464 sodium bichromate results in increased expression of RB1 mRNA CTD PMID:31558096 sodium dodecyl sulfate decreases expression ISO RGD:731712 6480464 Sodium Dodecyl Sulfate results in decreased expression of RB1 mRNA CTD PMID:31734321 sorafenib multiple interactions ISO RGD:731712 6480464 [sorafenib co-treated with letrozole] results in decreased expression of RB1 protein CTD PMID:20054642 sorafenib decreases expression ISO RGD:731712 6480464 sorafenib results in decreased expression of RB1 protein CTD PMID:17909054 , PMID:19633425 sorafenib decreases phosphorylation ISO RGD:731712 6480464 sorafenib results in decreased phosphorylation of RB1 protein CTD PMID:17909054 sulforaphane increases phosphorylation ISO RGD:731712 6480464 sulforaphane results in increased phosphorylation of RB1 protein CTD PMID:15231455 sulfur dioxide multiple interactions EXP 6480464 [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA more ... CTD PMID:19408242 , PMID:20064080 sulfur dioxide decreases expression EXP 6480464 Sulfur Dioxide results in decreased expression of RB1 mRNA, Sulfur Dioxide results in decreased expression of RB1 protein CTD PMID:19408242 more ... sulfur dioxide increases expression EXP 6480464 Sulfur Dioxide results in increased expression of RB1 protein CTD PMID:19408242 sulindac decreases expression ISO RGD:731712 6480464 Sulindac results in decreased expression of RB1 protein CTD PMID:16488075 sulindac sulfide affects activity ISO RGD:11219 6480464 sulindac sulfide affects the activity of RB1 protein CTD PMID:15694660 sunitinib increases expression ISO RGD:731712 6480464 Sunitinib results in increased expression of RB1 mRNA CTD PMID:31533062 T-2 toxin decreases phosphorylation EXP 6480464 T-2 Toxin results in decreased phosphorylation of RB1 protein CTD PMID:29567467 T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of RB1 mRNA CTD PMID:29567467 tamoxifen multiple interactions ISO RGD:731712 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tamoxifen results in decreased phosphorylation of RB1 protein], [Tamoxifen co-treated with FTI 277] results in decreased phosphorylation of RB1 protein CTD PMID:12866041 , PMID:14645110 tamoxifen multiple interactions EXP 6480464 [Tamoxifen results in increased expression of MIR106A mRNA] which results in decreased expression of RB1 protein CTD PMID:17343880 tamoxifen decreases expression EXP 6480464 Tamoxifen results in decreased expression of RB1 protein CTD PMID:17343880 tamoxifen increases phosphorylation ISO RGD:11219 6480464 Tamoxifen results in increased phosphorylation of RB1 protein CTD PMID:15642790 tamoxifen decreases phosphorylation ISO RGD:731712 6480464 Tamoxifen results in decreased phosphorylation of RB1 protein CTD PMID:14645110 tanespimycin multiple interactions ISO RGD:731712 6480464 [tanespimycin co-treated with Sirolimus] results in decreased phosphorylation of RB1 protein CTD PMID:17121904 tanespimycin decreases phosphorylation ISO RGD:731712 6480464 tanespimycin results in decreased phosphorylation of RB1 protein CTD PMID:17121904 Tanshinone I increases expression ISO RGD:11219 6480464 tanshinone results in increased expression of RB1 protein CTD PMID:18344322 Tanshinone I multiple interactions ISO RGD:11219 6480464 [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein more ... CTD PMID:18344322 tauroursodeoxycholic acid decreases expression EXP 6480464 ursodoxicoltaurine results in decreased expression of RB1 protein CTD PMID:15255934 tazarotene multiple interactions ISO RGD:731712 6480464 [tazarotene co-treated with Retinoids] results in decreased phosphorylation of RB1 protein CTD PMID:15383624 temozolomide multiple interactions ISO RGD:731712 6480464 [temozolomide co-treated with resveratrol] results in increased phosphorylation of RB1 protein CTD PMID:23522185 Temsirolimus multiple interactions ISO RGD:731712 6480464 temsirolimus promotes the reaction [2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol results in decreased phosphorylation of RB1 protein] CTD PMID:16954435 Temsirolimus decreases expression ISO RGD:731712 6480464 temsirolimus results in decreased expression of RB1 protein CTD PMID:16954435 terephthalic acid increases expression EXP 6480464 terephthalic acid results in increased expression of RB1 protein CTD PMID:16896691 terephthalic acid increases phosphorylation EXP 6480464 terephthalic acid results in increased phosphorylation of RB1 protein CTD PMID:16896691 teriflunomide decreases expression ISO RGD:731712 6480464 teriflunomide results in decreased expression of RB1 protein CTD PMID:19174558 tert-butyl hydroperoxide decreases expression ISO RGD:731712 6480464 tert-Butylhydroperoxide results in decreased expression of RB1 mRNA CTD PMID:12419474 , PMID:15336504 tetrachloromethane multiple interactions ISO RGD:11219 6480464 CDKN1A protein affects the reaction [Carbon Tetrachloride results in increased phosphorylation of RB1 protein] CTD PMID:12759355 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of RB mRNA CTD PMID:16644059 tetrachloromethane increases phosphorylation EXP 6480464 Carbon Tetrachloride results in increased phosphorylation of RB1 protein CTD PMID:17256749 tetrachloromethane increases phosphorylation ISO RGD:11219 6480464 Carbon Tetrachloride results in increased phosphorylation of RB1 protein CTD PMID:12759355 tetrachloromethane increases expression ISO RGD:11219 6480464 Carbon Tetrachloride results in increased expression of RB1 mRNA CTD PMID:15056808 theophylline multiple interactions ISO RGD:731712 6480464 [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein], [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RB1 protein CTD PMID:18951874 , PMID:9454737 thioacetamide multiple interactions EXP 6480464 Thioacetamide results in increased phosphorylation of and results in decreased activity of RB1 protein CTD PMID:15953624 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of RB1 mRNA CTD PMID:16337175 , PMID:26011634 thiophenes multiple interactions ISO RGD:731712 6480464 Thiophenes analog promotes the reaction [Tretinoin results in decreased phosphorylation of RB1 protein] CTD PMID:16140954 tocopherol decreases phosphorylation ISO RGD:731712 6480464 Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 tolbutamide decreases phosphorylation EXP 6480464 Tolbutamide results in decreased phosphorylation of RB1 protein CTD PMID:16718685 toluene increases phosphorylation EXP 6480464 Toluene results in increased phosphorylation of RB1 protein CTD PMID:9118908 toxaphene decreases expression ISO RGD:731712 6480464 Toxaphene results in decreased expression of RB1 protein CTD PMID:10048758 trametinib decreases phosphorylation ISO RGD:731712 6480464 trametinib results in decreased phosphorylation of RB1 protein CTD PMID:22733540 trans-isoeugenol decreases expression ISO RGD:731712 6480464 isoeugenol results in decreased expression of RB1 protein CTD PMID:22686307 trans-pinosylvin decreases expression ISO RGD:731712 6480464 pinosylvin results in decreased expression of RB1 protein CTD PMID:23333577 trichloroethene multiple interactions ISO RGD:11219 6480464 [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of RB1 protein modified form CTD PMID:33007382 trichostatin A affects expression ISO RGD:731712 6480464 [trichostatin A affects the expression of DNMT3B protein] which affects the expression of RB1 mRNA CTD PMID:18544619 trichostatin A increases expression ISO RGD:731712 6480464 trichostatin A results in increased expression of RB1 mRNA CTD PMID:24935251 trichostatin A multiple interactions ISO RGD:731712 6480464 trichostatin A results in decreased phosphorylation of and results in increased expression of RB1 protein CTD PMID:15179185 trichostatin A decreases activity ISO RGD:731712 6480464 trichostatin A results in decreased activity of RB1 protein CTD PMID:15494029 tris(2-chloroethyl) phosphate increases expression ISO RGD:731712 6480464 tris(chloroethyl)phosphate results in increased expression of RB1 protein, tris(chloroethyl)phosphate results in increased expression of RB1 protein modified form CTD PMID:28886428 troglitazone multiple interactions ISO RGD:731712 6480464 Aspirin inhibits the reaction [troglitazone results in decreased expression of RB1 protein modified form] more ... CTD PMID:15729575 , PMID:19908241 troglitazone decreases expression ISO RGD:731712 6480464 troglitazone results in decreased expression of RB protein modified form, troglitazone results in decreased expression of RB1 protein modified form CTD PMID:11343236 more ... troglitazone decreases expression ISO RGD:11219 6480464 troglitazone results in decreased expression of RB1 mRNA CTD PMID:28973697 troglitazone increases phosphorylation ISO RGD:731712 6480464 troglitazone results in increased phosphorylation of RB1 protein CTD PMID:11741176 troglitazone decreases phosphorylation ISO RGD:731712 6480464 troglitazone results in decreased phosphorylation of RB1 protein CTD PMID:12595159 troglitazone increases expression ISO RGD:731712 6480464 troglitazone results in increased expression of RB1 protein CTD PMID:19908241 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of RB1 mRNA CTD PMID:24136188 trovafloxacin decreases expression ISO RGD:11219 6480464 trovafloxacin results in decreased expression of RB1 mRNA CTD PMID:35537566 tunicamycin multiple interactions ISO RGD:11219 6480464 [Tunicamycin co-treated with HRAS protein] results in increased phosphorylation of RB1 protein, HSPA5 protein affects the reaction [[Tunicamycin co-treated with HRAS protein] results in increased phosphorylation of RB1 protein] CTD PMID:24898257 tyrphostin AG 1478 multiple interactions ISO RGD:731712 6480464 RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA], RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 protein] CTD PMID:24639330 urethane decreases expression ISO RGD:11219 6480464 Urethane results in decreased expression of RB1 mRNA CTD PMID:12117781 ursodeoxycholic acid decreases expression ISO RGD:731712 6480464 Ursodeoxycholic Acid results in decreased expression of RB1 protein modified form CTD PMID:17461466 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of RB1 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:731712 6480464 Valproic Acid results in decreased methylation of RB1 gene CTD PMID:29154799 valproic acid increases expression ISO RGD:731712 6480464 Valproic Acid results in increased expression of RB1 mRNA CTD PMID:24935251 valproic acid increases expression ISO RGD:11219 6480464 Valproic Acid results in increased expression of RB1 mRNA CTD PMID:20546886 , PMID:21427059 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of RB1 gene CTD PMID:31682807 vincristine multiple interactions ISO RGD:731712 6480464 [CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of RB1 protein more ... CTD PMID:28669723 , PMID:29187454 vinyl carbamate decreases expression ISO RGD:11219 6480464 vinyl carbamate results in decreased expression of RB1 mRNA CTD PMID:17849452 vorinostat multiple interactions ISO RGD:731712 6480464 [Bortezomib co-treated with vorinostat] results in increased degradation of RB1 protein, vorinostat results in decreased phosphorylation of and results in increased cleavage of RB1 protein CTD PMID:10597302 , PMID:12893773 vorinostat decreases phosphorylation ISO RGD:731712 6480464 vorinostat results in decreased phosphorylation of RB1 protein CTD PMID:14707268 vorinostat increases expression ISO RGD:731712 6480464 vorinostat results in increased expression of RB1 protein CTD PMID:15897598 wortmannin multiple interactions ISO RGD:11219 6480464 wortmannin inhibits the reaction [KITL protein results in increased phosphorylation of RB1 protein], wortmannin inhibits the reaction [Vanadates results in increased phosphorylation of RB1 protein] CTD PMID:10849422 , PMID:14971663 wortmannin multiple interactions EXP 6480464 Wortmannin inhibits the reaction [1, 1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Magnesium deficiency results in decreased phosphorylation of RB1 protein]] CTD PMID:30542433 Y-27632 multiple interactions ISO RGD:731712 6480464 Y 27632 promotes the reaction [4-amino-2-trifluoromethyl-phenyl retinate results in decreased expression of RB1 protein modified form] CTD PMID:32417439 Y-27632 decreases expression ISO RGD:731712 6480464 Y 27632 results in decreased expression of RB1 protein modified form CTD PMID:32417439 zebularine decreases expression ISO RGD:731712 6480464 pyrimidin-2-one beta-ribofuranoside results in decreased expression of RB1 protein modified form CTD PMID:23320119 zinc acetate multiple interactions ISO RGD:731712 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA CTD PMID:16357179 zinc acetate decreases expression ISO RGD:731712 6480464 Zinc Acetate results in decreased expression of RB1 mRNA CTD PMID:16357179 zinc atom multiple interactions ISO RGD:731712 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA CTD PMID:16979875 zinc sulfate decreases expression ISO RGD:731712 6480464 Zinc Sulfate results in decreased expression of RB1 mRNA CTD PMID:12756304 zinc(0) multiple interactions ISO RGD:731712 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA CTD PMID:16979875
