(1->4)-beta-D-glucan multiple interactions ISO RGD:1549982 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of HPRT mRNA CTD PMID:36331819 1,1,1-trichloroethane increases expression ISO RGD:1549982 6480464 1 more ... CTD PMID:25270620 1,2-dimethylhydrazine decreases expression ISO RGD:1549982 6480464 1, 2-Dimethylhydrazine results in decreased expression of HPRT mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:1549982 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HPRT mRNA CTD PMID:22206623 1-Methylpyrene multiple interactions ISO RGD:731296 6480464 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] more ... CTD PMID:25243916 1-nitropyrene multiple interactions ISO RGD:731296 6480464 CYP1A2 affects the reaction [1-nitropyrene results in increased mutagenesis of HPRT1 gene] CTD PMID:10727902 17alpha-ethynylestradiol multiple interactions ISO RGD:1549982 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HPRT1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:1549982 6480464 Ethinyl Estradiol results in increased expression of HPRT1 mRNA CTD PMID:17555576 , PMID:17942748 17beta-estradiol increases expression ISO RGD:1549982 6480464 Estradiol results in increased expression of HPRT1 mRNA CTD PMID:22467019 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of HPRT1 mRNA CTD PMID:26496021 2,2',4,5-tetrachlorobiphenyl multiple interactions ISO RGD:731296 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2 more ... CTD PMID:27913846 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:731296 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2 more ... CTD PMID:27913846 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1549982 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HPRT1 mRNA, Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to HPRT1 promoter] CTD PMID:17942748 , PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of HPRT1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731296 6480464 Tetrachlorodibenzodioxin affects the expression of HPRT1 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1549982 6480464 Tetrachlorodibenzodioxin affects the expression of HPRT1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HPRT1 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1549982 6480464 Tetrachlorodibenzodioxin results in increased expression of HPRT1 mRNA CTD PMID:17942748 2-Amino-9H-pyrido[2,3-b]indole multiple interactions ISO RGD:731296 6480464 [CYP1A2 protein co-treated with NAT2 gene polymorphism] promotes the reaction [2-amino-9H-pyrido(2, 3-b)indole binds to and results in increased mutagenesis of HPRT1 gene] CTD PMID:19243127 2-hydroxypropanoic acid decreases expression ISO RGD:731296 6480464 Lactic Acid results in decreased expression of HPRT1 mRNA CTD PMID:30851411 2-naphthylamine multiple interactions ISO RGD:731296 6480464 NAT2 polymorphism affects the reaction [2-Naphthylamine results in increased mutagenesis of HPRT gene] CTD PMID:36040704 3-Amino-1-methyl-5H-pyrido[4,3-b]indole increases mutagenesis ISO RGD:731296 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole results in increased mutagenesis of HPRT1 gene CTD PMID:2335011 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone increases mutagenesis EXP 6480464 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone results in increased mutagenesis of HPRT1 gene CTD PMID:17993254 3-chloropropane-1,2-diol affects expression EXP 6480464 alpha-Chlorohydrin affects the expression of HPRT1 mRNA CTD PMID:28522335 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of HPRT1 protein CTD PMID:34915118 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases mutagenesis EXP 6480464 2-amino-3-methylimidazo(4, 5-f)quinoline results in increased mutagenesis of HPRT1 gene CTD PMID:12467141 3-Nitrobenzanthrone multiple interactions ISO RGD:731296 6480464 [NAT2 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene, [SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene CTD PMID:17483118 3-phenylprop-2-enal decreases mutagenesis ISO RGD:731296 6480464 cinnamaldehyde results in decreased mutagenesis of HPRT1 gene CTD PMID:17178418 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of HPRT1 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane decreases expression ISO RGD:1549982 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of HPRT mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HPRT1 mRNA CTD PMID:36041667 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:1549982 6480464 [Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene, Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene] CTD PMID:15613823 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases mutagenesis ISO RGD:1549982 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene CTD PMID:15613823 4-hydroxynon-2-enal increases expression ISO RGD:1549982 6480464 4-hydroxy-2-nonenal results in increased expression of HPRT1 mRNA CTD PMID:19191707 4-nitroquinoline N-oxide increases mutagenesis ISO RGD:731296 6480464 4-Nitroquinoline-1-oxide results in increased mutagenesis of HPRT1 gene CTD PMID:26362870 , PMID:28454271 5-aza-2'-deoxycytidine increases expression ISO RGD:1549982 6480464 Decitabine results in increased expression of HPRT mRNA CTD PMID:27915011 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of HPRT1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of HPRT1 mRNA CTD PMID:19483382 acrylamide increases mutagenesis ISO RGD:1549982 6480464 Acrylamide results in increased mutagenesis of HPRT1 gene CTD PMID:15957192 acrylamide increases expression ISO RGD:731296 6480464 Acrylamide results in increased expression of HPRT1 mRNA CTD PMID:32763439 acrylamide increases mutagenesis EXP 6480464 Acrylamide results in increased mutagenesis of HPRT1 gene CTD PMID:20200216 acrylamide increases mutagenesis ISO RGD:731296 6480464 Acrylamide results in increased mutagenesis of HPRT1 gene CTD PMID:18407966 acrylonitrile multiple interactions ISO RGD:1549982 6480464 CYP2E1 gene mutant form inhibits the reaction [Acrylonitrile results in increased mutagenesis of HPRT gene] CTD PMID:32529832 acrylonitrile increases mutagenesis EXP 6480464 Acrylonitrile results in increased mutagenesis of HPRT gene CTD PMID:32529823 acrylonitrile increases mutagenesis ISO RGD:1549982 6480464 Acrylonitrile results in increased mutagenesis of HPRT gene CTD PMID:32529832 aldehydo-D-glucose decreases expression ISO RGD:731296 6480464 Glucose results in decreased expression of HPRT1 mRNA CTD PMID:31655124 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of HPRT1 mRNA CTD PMID:24977338 all-trans-retinoic acid decreases expression ISO RGD:731296 6480464 Tretinoin results in decreased expression of HPRT1 mRNA CTD PMID:21934132 more ... amiodarone affects expression EXP 6480464 Amiodarone affects the expression of HPRT1 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HPRT1 mRNA CTD PMID:16483693 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of HPRT1 mRNA CTD PMID:30779732 aristolochic acid A decreases expression ISO RGD:731296 6480464 aristolochic acid I results in decreased expression of HPRT1 mRNA CTD PMID:33212167 aristolochic acid A increases expression ISO RGD:731296 6480464 aristolochic acid I results in increased expression of HPRT1 protein CTD PMID:33212167 Aroclor 1254 decreases expression ISO RGD:1549982 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of HPRT1 mRNA CTD PMID:23650126 arsenite(3-) multiple interactions ISO RGD:731296 6480464 arsenite inhibits the reaction [G3BP1 protein binds to HPRT1 protein] CTD PMID:32406909 atrazine decreases expression ISO RGD:731296 6480464 Atrazine results in decreased expression of HPRT1 mRNA CTD PMID:22378314 azathioprine increases mutagenesis ISO RGD:1549982 6480464 Azathioprine results in increased mutagenesis of HPRT gene CTD PMID:16107271 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of HPRT1 mRNA CTD PMID:19483382 benzene increases mutagenesis ISO RGD:1549982 6480464 Benzene results in increased mutagenesis of HPRT gene CTD PMID:20035728 benzo[a]pyrene multiple interactions ISO RGD:1549982 6480464 Benzo(a)pyrene affects the reaction [AHR protein binds to HPRT1 promoter], POLB protein promotes the reaction [Benzo(a)pyrene results in increased mutagenesis of HPRT gene] CTD PMID:19654925 , PMID:23652152 benzo[a]pyrene affects methylation ISO RGD:731296 6480464 Benzo(a)pyrene affects the methylation of HPRT1 promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:731296 6480464 Benzo(a)pyrene results in increased methylation of HPRT1 5' UTR CTD PMID:27901495 benzo[a]pyrene increases mutagenesis ISO RGD:1549982 6480464 Benzo(a)pyrene results in increased mutagenesis of HPRT gene CTD PMID:23652152 benzo[a]pyrene increases expression ISO RGD:731296 6480464 Benzo(a)pyrene results in increased expression of HPRT1 mRNA CTD PMID:16269432 benzo[a]pyrene multiple interactions ISO RGD:731296 6480464 [[POR protein co-treated with CYP3A4 protein] results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene more ... CTD PMID:17525473 , PMID:27913846 benzo[a]pyrene increases expression ISO RGD:1549982 6480464 Benzo(a)pyrene results in increased expression of HPRT1 mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:1549982 6480464 POLH mutant form inhibits the reaction [7 more ... CTD PMID:22745795 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:731296 6480464 POLH mutant form inhibits the reaction [7 more ... CTD PMID:22745795 benzo[a]pyrene diol epoxide I increases mutagenesis ISO RGD:1549982 6480464 7 more ... CTD PMID:22745795 benzo[a]pyrene diol epoxide I increases mutagenesis ISO RGD:731296 6480464 7 more ... CTD PMID:22745795 Benzo[a]pyrene-7,8-diol multiple interactions ISO RGD:731296 6480464 CYP1A1 protein promotes the reaction [benzo(a)pyrene 7 more ... CTD PMID:17525473 beta-carotene multiple interactions EXP 6480464 beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 biphenyl-4-amine multiple interactions ISO RGD:731296 6480464 [NAT1 polymorphism results in increased susceptibility to 4-biphenylamine] which results in increased mutagenesis of HPRT1 gene, NAT2 polymorphism affects the reaction [4-biphenylamine results in increased mutagenesis of HPRT gene] CTD PMID:22114069 , PMID:36040704 bis(2-chloroethyl) sulfide affects expression EXP 6480464 Mustard Gas affects the expression of HPRT mRNA CTD PMID:15651846 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1549982 6480464 Diethylhexyl Phthalate results in increased expression of HPRT1 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1549982 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of HPRT1 mRNA] CTD PMID:19850644 bisphenol A increases expression ISO RGD:1549982 6480464 bisphenol A results in increased expression of HPRT mRNA CTD PMID:25270620 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HPRT1 mRNA CTD PMID:34947998 bisphenol A decreases expression ISO RGD:731296 6480464 bisphenol A results in decreased expression of HPRT1 mRNA CTD PMID:29275510 , PMID:33670352 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of HPRT1 protein CTD PMID:22649256 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of HPRT1 mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HPRT1 mRNA, [bisphenol A co-treated with Estradiol] results in decreased expression of HPRT1 mRNA CTD PMID:26496021 , PMID:36041667 Bisphenol B increases expression ISO RGD:731296 6480464 bisphenol B results in increased expression of HPRT1 protein CTD PMID:34186270 bisphenol F increases expression ISO RGD:731296 6480464 bisphenol F results in increased expression of HPRT1 protein CTD PMID:34186270 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HPRT1 mRNA CTD PMID:36041667 Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of HPRT1 protein CTD PMID:28903499 buspirone increases expression EXP 6480464 Buspirone results in increased expression of HPRT1 mRNA CTD PMID:24136188 buta-1,3-diene increases mutagenesis EXP 6480464 1 more ... CTD PMID:20017413 more ... buta-1,3-diene increases mutagenesis ISO RGD:731296 6480464 1, 3-butadiene metabolite results in increased mutagenesis of HPRT1 gene CTD PMID:20853577 buta-1,3-diene increases mutagenesis ISO RGD:1549982 6480464 1 more ... CTD PMID:20017413 more ... cadmium dichloride multiple interactions ISO RGD:1549982 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HPRT mRNA CTD PMID:19840844 caffeine increases expression EXP 6480464 Caffeine results in increased expression of HPRT1 protein CTD PMID:6149265 calcitriol multiple interactions ISO RGD:731296 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of HPRT1 mRNA CTD PMID:21592394 calcitriol decreases expression ISO RGD:731296 6480464 Calcitriol results in decreased expression of HPRT1 mRNA CTD PMID:21592394 calyculin a increases expression ISO RGD:1549982 6480464 calyculin A results in increased expression of HPRT mRNA CTD PMID:25270620 carbon nanotube increases expression ISO RGD:1549982 6480464 Nanotubes more ... CTD PMID:25620056 carmustine increases mutagenesis ISO RGD:1549982 6480464 Carmustine results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 chromium(6+) increases mutagenesis ISO RGD:731296 6480464 chromium hexavalent ion results in increased mutagenesis of HPRT1 gene CTD PMID:7508562 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of HPRT1 mRNA CTD PMID:19483382 clofibrate increases expression ISO RGD:1549982 6480464 Clofibrate results in increased expression of HPRT mRNA CTD PMID:17585979 clofibrate multiple interactions ISO RGD:1549982 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HPRT mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HPRT mRNA] CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HPRT1 mRNA CTD PMID:17602206 cobalt dichloride decreases expression ISO RGD:731296 6480464 cobaltous chloride results in decreased expression of HPRT1 mRNA CTD PMID:19320972 coumarin decreases phosphorylation ISO RGD:731296 6480464 coumarin results in decreased phosphorylation of HPRT1 protein CTD PMID:35688186 coumestrol increases expression ISO RGD:731296 6480464 Coumestrol results in increased expression of HPRT1 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO RGD:731296 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 curcumin increases expression ISO RGD:731296 6480464 Curcumin results in increased expression of HPRT1 mRNA CTD PMID:16101141 cyclophosphamide increases mutagenesis ISO RGD:1549982 6480464 Cyclophosphamide results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 cyclophosphamide increases mutagenesis EXP 6480464 Cyclophosphamide results in increased mutagenesis of HPRT1 gene CTD PMID:23677247 cyclosporin A increases expression ISO RGD:731296 6480464 Cyclosporine results in increased expression of HPRT1 mRNA CTD PMID:27989131 cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of HPRT1 mRNA CTD PMID:29727961 cyproconazole decreases expression ISO RGD:1549982 6480464 cyproconazole results in decreased expression of HPRT mRNA CTD PMID:22045034 cyproconazole increases expression ISO RGD:1549982 6480464 cyproconazole results in increased expression of HPRT mRNA CTD PMID:22334560 D-glucose decreases expression ISO RGD:731296 6480464 Glucose results in decreased expression of HPRT1 mRNA CTD PMID:31655124 D-mannitol increases expression ISO RGD:1549982 6480464 Mannitol results in increased expression of HPRT mRNA CTD PMID:25270620 deguelin increases expression ISO RGD:731296 6480464 deguelin results in increased expression of HPRT1 mRNA CTD PMID:33512557 dibutyl phthalate multiple interactions ISO RGD:1549982 6480464 [Ozone co-treated with Dibutyl Phthalate] results in increased mutagenesis of HPRT1 gene, Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene] CTD PMID:15613823 dibutyl phthalate increases mutagenesis ISO RGD:1549982 6480464 Dibutyl Phthalate results in increased mutagenesis of HPRT1 gene CTD PMID:15613823 dichlorine increases expression EXP 6480464 Chlorine results in increased expression of HPRT mRNA CTD PMID:18636392 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of HPRT mRNA CTD PMID:18636392 diepoxybutane increases mutagenesis ISO RGD:731296 6480464 diepoxybutane results in increased mutagenesis of HPRT1 gene CTD PMID:20853577 Diisodecyl phthalate increases expression ISO RGD:1549982 6480464 diisodecyl phthalate results in increased expression of HPRT mRNA CTD PMID:25270620 dimethyl sulfoxide decreases expression EXP 6480464 Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA CTD PMID:12883083 dioxygen decreases expression ISO RGD:731296 6480464 Oxygen deficiency results in decreased expression of HPRT1 mRNA CTD PMID:35883890 dorsomorphin multiple interactions ISO RGD:731296 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPRT1 mRNA CTD PMID:27188386 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of HPRT1 mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO RGD:731296 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HPRT1 mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO RGD:731296 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of HPRT1 protein CTD PMID:23301498 epoxiconazole increases expression ISO RGD:1549982 6480464 epoxiconazole results in increased expression of HPRT mRNA CTD PMID:22334560 ethanol increases expression ISO RGD:1549982 6480464 Ethanol results in increased expression of HPRT mRNA CTD PMID:30319688 ethyl methanesulfonate increases mutagenesis EXP 6480464 Ethyl Methanesulfonate results in increased mutagenesis of HPRT1 gene CTD PMID:7728755 fenthion increases expression ISO RGD:1549982 6480464 Fenthion results in increased expression of HPRT mRNA CTD PMID:34813904 fipronil increases expression EXP 6480464 fipronil results in increased expression of HPRT1 mRNA CTD PMID:23962444 folic acid multiple interactions ISO RGD:1549982 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HPRT mRNA CTD PMID:22206623 fructose decreases expression ISO RGD:731296 6480464 Fructose results in decreased expression of HPRT1 mRNA CTD PMID:31655124 fumonisin B1 increases expression ISO RGD:1549982 6480464 fumonisin B1 results in increased expression of HPRT mRNA CTD PMID:16221962 gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of HPRT1 mRNA CTD PMID:17785943 genistein decreases expression ISO RGD:731296 6480464 Genistein results in decreased expression of HPRT1 mRNA CTD PMID:22228119 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of HPRT1 mRNA CTD PMID:33387578 glucose decreases expression ISO RGD:731296 6480464 Glucose results in decreased expression of HPRT1 mRNA CTD PMID:31655124 gold atom decreases expression ISO RGD:731296 6480464 Gold results in decreased expression of HPRT1 mRNA CTD PMID:25523186 gold(0) decreases expression ISO RGD:731296 6480464 Gold results in decreased expression of HPRT1 mRNA CTD PMID:25523186 hexaconazole decreases expression ISO RGD:1549982 6480464 hexaconazole results in decreased expression of HPRT mRNA CTD PMID:22045034 hydrogen peroxide increases mutagenesis ISO RGD:731296 6480464 Hydrogen Peroxide results in increased mutagenesis of HPRT1 gene CTD PMID:22539617 , PMID:7508562 hypochlorous acid increases mutagenesis ISO RGD:731296 6480464 Hypochlorous Acid results in increased mutagenesis of HPRT1 gene CTD PMID:19892774 inulin multiple interactions ISO RGD:1549982 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of HPRT mRNA CTD PMID:36331819 isoniazide increases expression EXP 6480464 Isoniazid results in increased expression of HPRT1 mRNA CTD PMID:12883083 ivermectin decreases expression ISO RGD:731296 6480464 Ivermectin results in decreased expression of HPRT1 protein CTD PMID:32959892 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of HPRT1 mRNA CTD PMID:19483382 lead diacetate decreases activity ISO RGD:731296 6480464 lead acetate results in decreased activity of HPRT1 protein CTD PMID:19428946 lead diacetate decreases expression ISO RGD:1549982 6480464 lead acetate results in decreased expression of HPRT mRNA CTD PMID:21829687 lead diacetate decreases activity EXP 6480464 lead acetate results in decreased activity of HPRT1 protein CTD PMID:19428946 lithium atom increases expression EXP 6480464 Lithium results in increased expression of HPRT1 protein CTD PMID:18296634 lithium hydride increases expression EXP 6480464 Lithium results in increased expression of HPRT1 protein CTD PMID:18296634 MeIQ increases mutagenesis EXP 6480464 2-amino-3 more ... CTD PMID:12467141 MeIQx increases mutagenesis EXP 6480464 2-amino-3 more ... CTD PMID:12467141 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of HPRT1 mRNA CTD PMID:28935588 methidathion increases expression ISO RGD:1549982 6480464 methidathion results in increased expression of HPRT mRNA CTD PMID:34813904 methotrexate decreases expression ISO RGD:731296 6480464 Methotrexate results in decreased expression of HPRT1 mRNA CTD PMID:17400583 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of HPRT1 gene CTD PMID:23303685 microcystin-LR increases mutagenesis ISO RGD:731296 6480464 cyanoginosin LR results in increased mutagenesis of HPRT gene CTD PMID:36435412 microcystin-LR multiple interactions ISO RGD:731296 6480464 BLK protein inhibits the reaction [cyanoginosin LR results in increased mutagenesis of HPRT gene] CTD PMID:36435412 N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of HPRT1 gene CTD PMID:22167886 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:1549982 6480464 Ethylnitrosourea results in increased mutagenesis of HPRT gene CTD PMID:32529823 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:1549982 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HPRT mRNA more ... CTD PMID:19840844 N-methyl-N-nitrosourea increases mutagenesis EXP 6480464 Methylnitrosourea results in increased mutagenesis of HPRT1 gene CTD PMID:18249417 N-methyl-N-nitrosourea increases expression ISO RGD:1549982 6480464 Methylnitrosourea results in increased expression of HPRT mRNA CTD PMID:25270620 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HPRT1 mRNA CTD PMID:17602206 N-nitrosodimethylamine multiple interactions ISO RGD:731296 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine] which results in increased mutagenesis of HPRT1 gene CTD PMID:27913846 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of HPRT1 mRNA CTD PMID:24136188 neoglucobrassicin increases mutagenesis ISO RGD:731296 6480464 1-methoxy-3-indolylmethylglucosinolate metabolite results in increased mutagenesis of HPRT1 gene CTD PMID:20846518 nickel sulfate affects expression ISO RGD:731296 6480464 nickel sulfate affects the expression of HPRT1 mRNA CTD PMID:18202158 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of HPRT1 mRNA CTD PMID:24136188 nitric oxide increases mutagenesis ISO RGD:731296 6480464 Nitric Oxide results in increased mutagenesis of HPRT1 gene CTD PMID:22303861 , PMID:28454271 okadaic acid multiple interactions ISO RGD:1549982 6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of HPRT mRNA CTD PMID:19840844 okadaic acid increases expression ISO RGD:1549982 6480464 Okadaic Acid results in increased expression of HPRT mRNA CTD PMID:25270620 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of HPRT1 mRNA CTD PMID:19483382 oxirane increases mutagenesis ISO RGD:1549982 6480464 Ethylene Oxide results in increased mutagenesis of HPRT gene CTD PMID:10636004 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of HPRT mRNA CTD PMID:18636392 ozone increases mutagenesis ISO RGD:1549982 6480464 Ozone results in increased mutagenesis of HPRT1 gene CTD PMID:15613823 ozone multiple interactions ISO RGD:1549982 6480464 [Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene more ... CTD PMID:15613823 p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of HPRT1 mRNA CTD PMID:27638505 paracetamol multiple interactions ISO RGD:1549982 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HPRT mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HPRT mRNA] CTD PMID:17585979 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of HPRT1 mRNA CTD PMID:12883083 paraquat increases expression ISO RGD:1549982 6480464 Paraquat results in increased expression of HPRT1 mRNA CTD PMID:21371552 pent-4-enoic acid increases expression EXP 6480464 4-pentenoic acid results in increased expression of HPRT1 mRNA CTD PMID:12883083 pentachlorophenol multiple interactions ISO RGD:731296 6480464 Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene], Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1549982 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of HPRT mRNA more ... CTD PMID:36331819 perfluorooctanoic acid increases expression ISO RGD:1549982 6480464 perfluorooctanoic acid results in increased expression of HPRT1 mRNA CTD PMID:23626681 perfluorooctanoic acid multiple interactions ISO RGD:1549982 6480464 Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of HPRT1 mRNA] CTD PMID:23626681 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of HPRT1 mRNA CTD PMID:16940010 PhIP increases mutagenesis EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased mutagenesis of HPRT1 gene CTD PMID:11289141 , PMID:12467141 PhIP increases mutagenesis ISO RGD:731296 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:10728688 more ... PhIP multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:12467141 PhIP multiple interactions ISO RGD:731296 6480464 [2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:7728948 , PMID:8625468 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1549982 6480464 [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT mRNA CTD PMID:19840844 picoxystrobin increases expression ISO RGD:731296 6480464 picoxystrobin results in increased expression of HPRT1 mRNA CTD PMID:33512557 pirinixic acid increases expression ISO RGD:1549982 6480464 pirinixic acid results in increased expression of HPRT mRNA, pirinixic acid results in increased expression of HPRT1 mRNA CTD PMID:16221962 more ... pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of HPRT1 mRNA CTD PMID:19483382 pirinixic acid multiple interactions ISO RGD:1549982 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of HPRT mRNA] CTD PMID:20059764 potassium bromate increases mutagenesis ISO RGD:1549982 6480464 potassium bromate results in increased mutagenesis of HPRT gene CTD PMID:19853637 potassium bromate increases mutagenesis ISO RGD:731296 6480464 potassium bromate results in increased mutagenesis of HPRT1 gene CTD PMID:22539617 potassium dichromate increases mutagenesis ISO RGD:731296 6480464 Potassium Dichromate results in increased mutagenesis of HPRT1 gene CTD PMID:7508562 propiconazole increases expression ISO RGD:1549982 6480464 propiconazole results in increased expression of HPRT mRNA, propiconazole results in increased expression of HPRT1 mRNA CTD PMID:21278054 , PMID:22334560 pyrogallol increases expression ISO RGD:1549982 6480464 Pyrogallol results in increased expression of HPRT1 mRNA CTD PMID:20362636 rac-lactic acid decreases expression ISO RGD:731296 6480464 Lactic Acid results in decreased expression of HPRT1 mRNA CTD PMID:30851411 resveratrol multiple interactions ISO RGD:731296 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of HPRT1 mRNA CTD PMID:19167446 resveratrol decreases expression ISO RGD:731296 6480464 resveratrol results in decreased expression of HPRT1 protein CTD PMID:23724044 retinyl acetate increases expression ISO RGD:1549982 6480464 retinol acetate results in increased expression of HPRT1 mRNA CTD PMID:16772331 rotenone increases expression ISO RGD:731296 6480464 Rotenone results in increased expression of HPRT1 mRNA CTD PMID:33512557 SB 431542 multiple interactions ISO RGD:731296 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPRT1 mRNA CTD PMID:27188386 sodium arsenite multiple interactions ISO RGD:731296 6480464 [ATF4 mutant form results in increased susceptibility to sodium arsenite] which results in increased mutagenesis of HPRT1 gene, APEX1 inhibits the reaction [[ATF4 mutant form results in increased susceptibility to sodium arsenite] which results in increased mutagenesis of HPRT1 gene] CTD PMID:17938202 sodium arsenite decreases expression ISO RGD:1549982 6480464 sodium arsenite results in decreased expression of HPRT mRNA CTD PMID:36209798 sodium arsenite increases expression ISO RGD:731296 6480464 sodium arsenite results in increased expression of HPRT1 mRNA CTD PMID:34032870 sodium arsenite increases expression ISO RGD:1549982 6480464 sodium arsenite results in increased expression of HPRT1 protein CTD PMID:29044176 styrene multiple interactions ISO RGD:731296 6480464 GSTP1 gene polymorphism promotes the reaction [Styrene results in increased mutagenesis of HPRT1 gene] CTD PMID:12893075 styrene increases mutagenesis ISO RGD:731296 6480464 Styrene results in increased mutagenesis of HPRT1 gene CTD PMID:11535253 , PMID:12893075 tamoxifen affects expression ISO RGD:1549982 6480464 Tamoxifen affects the expression of HPRT1 mRNA CTD PMID:17555576 temozolomide increases mutagenesis ISO RGD:1549982 6480464 temozolomide results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 temozolomide multiple interactions ISO RGD:1549982 6480464 MGMT protein inhibits the reaction [temozolomide results in increased mutagenesis of HPRT1 gene] CTD PMID:17116724 testosterone multiple interactions ISO RGD:731296 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of HPRT1 mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:731296 6480464 Testosterone results in decreased expression of HPRT1 mRNA CTD PMID:21592394 tetrachloromethane increases expression ISO RGD:1549982 6480464 Carbon Tetrachloride results in increased expression of HPRT mRNA CTD PMID:31919559 thapsigargin decreases expression ISO RGD:731296 6480464 Thapsigargin results in decreased expression of HPRT1 mRNA CTD PMID:22378314 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of HPRT1 mRNA CTD PMID:19483382 Thiotepa increases mutagenesis EXP 6480464 Thiotepa results in increased mutagenesis of HPRT gene CTD PMID:10069464 tioguanine decreases response to substance ISO RGD:731296 6480464 HPRT1 gene mutant form results in decreased susceptibility to Thioguanine CTD PMID:28446605 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of HPRT1 mRNA CTD PMID:33387578 trimellitic anhydride increases expression ISO RGD:1549982 6480464 trimellitic anhydride results in increased expression of HPRT1 mRNA CTD PMID:19042947 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of HPRT1 mRNA CTD PMID:30589522 troglitazone decreases expression ISO RGD:731296 6480464 troglitazone results in decreased expression of HPRT1 mRNA CTD PMID:19631733 tungsten increases expression ISO RGD:1549982 6480464 Tungsten results in increased expression of HPRT mRNA CTD PMID:30912803 tunicamycin decreases expression ISO RGD:731296 6480464 Tunicamycin results in decreased expression of HPRT1 mRNA CTD PMID:22378314 valproic acid increases expression ISO RGD:731296 6480464 Valproic Acid results in increased expression of HPRT1 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:731296 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPRT1 mRNA CTD PMID:27188386 vanillin decreases mutagenesis ISO RGD:731296 6480464 vanillin results in decreased mutagenesis of HPRT1 gene CTD PMID:17178418 vitamin E multiple interactions EXP 6480464 Vitamin E inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 zidovudine increases mutagenesis ISO RGD:731296 6480464 Zidovudine results in increased mutagenesis of HPRT1 exon CTD PMID:10526209
