Tacstd2 (tumor-associated calcium signal transducer 2) - Rat Genome Database

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Gene: Tacstd2 (tumor-associated calcium signal transducer 2) Rattus norvegicus
Analyze
Symbol: Tacstd2
Name: tumor-associated calcium signal transducer 2
RGD ID: 1359498
Description: Predicted to be involved in several processes, including negative regulation of branching involved in ureteric bud morphogenesis; negative regulation of cellular component organization; and negative regulation of substrate adhesion-dependent cell spreading. Predicted to be located in basal plasma membrane and lateral plasma membrane. Predicted to be active in extracellular space and nucleus. Human ortholog(s) of this gene implicated in corneal dystrophy and gelatinous drop-like corneal dystrophy. Orthologous to human TACSTD2 (tumor associated calcium signal transducer 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC72570; parturition-related protein 1; Prp1; Trop2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8498,037,620 - 98,039,320 (-)NCBIGRCr8
mRatBN7.2496,707,950 - 96,709,650 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,707,951 - 96,709,650 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,963,680 - 101,965,380 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,738,651 - 97,740,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0496,165,839 - 96,167,539 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,341,187 - 98,342,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,341,188 - 98,342,887 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,126,801 - 163,128,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4497,803,151 - 97,804,851 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1498,047,632 - 98,049,313 (-)NCBI
Celera491,374,254 - 91,375,954 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-palmitoylglycerol  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinoic acid  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
amphotericin B  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexane  (EXP)
hydrogen peroxide  (ISO)
isobutanol  (ISO)
isotretinoin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
Licochalcone B  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
testosterone  (ISO)
tetrathiomolybdate(2-)  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
basal plasma membrane  (IEA,ISO,ISS)
extracellular space  (IBA,IEA,ISO)
lateral plasma membrane  (IEA,ISO,ISS)
membrane  (ISO)
nucleus  (IBA,IEA,ISO)
plasma membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Identification of the gene responsible for gelatinous drop-like corneal dystrophy. Tsujikawa M, etal., Nat Genet. 1999 Apr;21(4):420-3.
Additional References at PubMed
PMID:9462726   PMID:19199708   PMID:21743029   PMID:22194864   PMID:23070813   PMID:23376485  


Genomics

Comparative Map Data
Tacstd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8498,037,620 - 98,039,320 (-)NCBIGRCr8
mRatBN7.2496,707,950 - 96,709,650 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,707,951 - 96,709,650 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,963,680 - 101,965,380 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,738,651 - 97,740,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0496,165,839 - 96,167,539 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,341,187 - 98,342,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,341,188 - 98,342,887 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,126,801 - 163,128,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4497,803,151 - 97,804,851 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1498,047,632 - 98,049,313 (-)NCBI
Celera491,374,254 - 91,375,954 (-)NCBICelera
Cytogenetic Map4q31NCBI
TACSTD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38158,575,433 - 58,577,252 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl158,575,433 - 58,577,252 (-)EnsemblGRCh38hg38GRCh38
GRCh37159,041,105 - 59,042,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36158,813,231 - 58,816,033 (-)NCBINCBI36Build 36hg18NCBI36
Build 34158,752,663 - 58,755,466NCBI
Celera157,324,947 - 57,327,018 (-)NCBICelera
Cytogenetic Map1p32.1NCBI
HuRef157,151,670 - 57,153,741 (-)NCBIHuRef
CHM1_1159,156,449 - 59,158,520 (-)NCBICHM1_1
T2T-CHM13v2.0158,453,397 - 58,455,216 (-)NCBIT2T-CHM13v2.0
Tacstd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39667,511,043 - 67,512,806 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl667,511,046 - 67,512,780 (-)EnsemblGRCm39 Ensembl
GRCm38667,534,059 - 67,535,822 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl667,534,062 - 67,535,796 (-)EnsemblGRCm38mm10GRCm38
MGSCv37667,484,053 - 67,485,816 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36667,463,640 - 67,465,374 (-)NCBIMGSCv36mm8
Celera669,652,700 - 69,654,464 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.88NCBI
Tacstd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554641,282,989 - 1,284,785 (+)NCBIChiLan1.0ChiLan1.0
TACSTD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21168,269,077 - 168,271,255 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,421,430 - 167,423,741 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0157,838,661 - 57,841,444 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1159,544,868 - 59,547,207 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl159,545,625 - 59,546,596 (-)Ensemblpanpan1.1panPan2
TACSTD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1551,122,469 - 51,123,753 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha551,187,934 - 51,189,787 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0551,303,042 - 51,304,084 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1551,252,727 - 51,254,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0551,198,006 - 51,199,866 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0551,481,572 - 51,483,437 (+)NCBIUU_Cfam_GSD_1.0
Tacstd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505872,207,616 - 72,209,632 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365223,206,957 - 3,207,919 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365223,206,826 - 3,208,675 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TACSTD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6153,859,482 - 153,861,492 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16153,859,488 - 153,861,508 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26141,453,653 - 141,455,459 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TACSTD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12074,403,547 - 74,406,756 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603342,956,630 - 42,959,787 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tacstd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248621,721,030 - 1,722,780 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tacstd2
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:90
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000010156
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
2317587Eae26Experimental allergic encephalomyelitis QTL 26nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)488656681103194984Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat

Markers in Region
AI575674  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2496,708,041 - 96,708,228 (+)MAPPERmRatBN7.2
Rnor_6.0498,341,279 - 98,341,465NCBIRnor6.0
Rnor_5.04163,126,893 - 163,127,079UniSTSRnor5.0
RGSC_v3.4497,803,243 - 97,803,429UniSTSRGSC3.4
Celera491,374,346 - 91,374,532UniSTS
RH 3.4 Map4607.7UniSTS
Cytogenetic Map4q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 4 11
Low 3 2 8 7 1 1 25 27 27 1
Below cutoff 5 35 32 7 32 7 8 33 5 7

Sequence


RefSeq Acc Id: ENSRNOT00000010156   ⟹   ENSRNOP00000010156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl496,707,951 - 96,709,650 (-)Ensembl
Rnor_6.0 Ensembl498,341,188 - 98,342,887 (-)Ensembl
RefSeq Acc Id: NM_001009540   ⟹   NP_001009540
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8498,037,620 - 98,039,320 (-)NCBI
mRatBN7.2496,707,950 - 96,709,650 (-)NCBI
Rnor_6.0498,341,187 - 98,342,887 (-)NCBI
Rnor_5.04163,126,801 - 163,128,501 (-)NCBI
RGSC_v3.4497,803,151 - 97,804,851 (-)RGD
Celera491,374,254 - 91,375,954 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009540 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH60519 (Get FASTA)   NCBI Sequence Viewer  
  AAO67351 (Get FASTA)   NCBI Sequence Viewer  
  EDL91571 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010156
  ENSRNOP00000010156.2
  ENSRNOP00065042943
GenBank Protein Q6P9Z6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009540   ⟸   NM_001009540
- Peptide Label: precursor
- UniProtKB: Q6K0P4 (UniProtKB/Swiss-Prot),   Q6P9Z6 (UniProtKB/Swiss-Prot),   A0A0G2JSJ1 (UniProtKB/TrEMBL),   A6KF53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010156   ⟸   ENSRNOT00000010156
Protein Domains
Thyroglobulin type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P9Z6-F1-model_v2 AlphaFold Q6P9Z6 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693104
Promoter ID:EPDNEW_R3628
Type:single initiation site
Name:Tacstd2_1
Description:tumor-associated calcium signal transducer 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0498,342,887 - 98,342,947EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359498 AgrOrtholog
BioCyc Gene G2FUF-44558 BioCyc
Ensembl Genes ENSRNOG00000007740 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00065030258 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010156 ENTREZGENE
  ENSRNOT00000010156.6 UniProtKB/TrEMBL
  ENSRNOT00065052197 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.800.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5597863 IMAGE-MGC_LOAD
InterPro EPCAM-Trop-2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPCAM/Trop-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EpCAM_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:494343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72570 IMAGE-MGC_LOAD
NCBI Gene 494343 ENTREZGENE
PANTHER PTHR14168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EPCAM-Trop-2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EpCAM_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tacstd2 PhenoGen
PROSITE THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007740 RatGTEx
  ENSRNOG00065030258 RatGTEx
SMART SM00211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57610 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSJ1 ENTREZGENE, UniProtKB/TrEMBL
  A6KF53 ENTREZGENE, UniProtKB/TrEMBL
  Q6K0P4 ENTREZGENE
  Q6P9Z6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6K0P4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Tacstd2  tumor-associated calcium signal transducer 2      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Tacstd2  tumor-associated calcium signal transducer 2      Symbol and Name status set to provisional 70820 PROVISIONAL