Gene: Mcm2 (minichromosome maintenance complex component 2) Rattus norvegicus
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Symbol: Mcm2
Name: minichromosome maintenance complex component 2
Description: ENCODES a protein that exhibits DNA replication origin binding (ortholog); enzyme binding (ortholog); histone binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to interleukin-4 (ortholog); cochlea development (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; DNA replication pathway; ASSOCIATED WITH Chronic Cerebral Hypoperfusion; Alzheimer's disease (ortholog); autosomal dominant nonsyndromic deafness 70 (ortholog); FOUND IN nucleus; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA replication licensing factor MCM2; LOC312538; minichromosome maintenance deficient 2 mitotin; minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
Orthologs:
Homo sapiens (human) : MCM2 (minichromosome maintenance complex component 2)  HGNC  Alliance
Mus musculus (house mouse) : Mcm2 (minichromosome maintenance complex component 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcm2 (minichromosome maintenance complex component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MCM2 (minichromosome maintenance complex component 2)
Canis lupus familiaris (dog) : MCM2 (minichromosome maintenance complex component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcm2 (minichromosome maintenance complex component 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04120,825,699 - 120,840,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04186,066,380 - 186,080,902 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,977,522 - 122,991,934 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14123,222,510 - 123,235,450 (-)NCBI
Celera4110,299,649 - 110,314,061 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mcm2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305577
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE