Piga (phosphatidylinositol glycan anchor biosynthesis, class A) - Rat Genome Database

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Gene: Piga (phosphatidylinositol glycan anchor biosynthesis, class A) Rattus norvegicus
Analyze
Symbol: Piga
Name: phosphatidylinositol glycan anchor biosynthesis, class A
RGD ID: 1589723
Description: Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 2 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGA (phosphatidylinositol glycan anchor biosynthesis class A); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; INTERACTS WITH 1,3-Propane sultone; 1,4-phenylenediamine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein; phosphatidylinositol glycan, class A; phosphatidylinositol glycan, class A (mapped); phosphatidylinositol N-acetylglucosaminyltransferase subunit A; Piga_mapped
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X33,672,832 - 33,687,747 (-)NCBIGRCr8
mRatBN7.2X30,043,033 - 30,055,861 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX30,042,343 - 30,055,804 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX31,082,324 - 31,095,044 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X34,512,908 - 34,525,604 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X30,706,657 - 30,719,377 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X31,786,823 - 31,799,751 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX31,786,194 - 31,799,560 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X32,160,574 - 32,173,353 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X50,797,413 - 50,812,217 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX30,389,874 - 30,399,559 (-)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethene  (ISO)
1,3-Propane sultone  (EXP)
1,4-phenylenediamine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,4,3',4'-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-nitroquinoline N-oxide  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
aristolochic acids  (EXP)
Aroclor 1254  (ISO)
azathioprine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorambucil  (EXP)
choline  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (EXP,ISO)
etoposide  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
glucose  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
melphalan  (EXP)
methyl methanesulfonate  (EXP)
morphine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-ethyl-N-nitrosourea  (EXP,ISO)
N-methyl-N-nitrosourea  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
paracetamol  (EXP,ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
pyrene  (EXP)
rac-lactic acid  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
Thiotepa  (EXP)
trans-1,2-dichloroethene  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The spectrum of PIG-A gene mutations in aplastic anemia/paroxysmal nocturnal hemoglobinuria (AA/PNH): a high incidence of multiple mutations and evidence of a mutational hot spot. Mortazavi Y, etal., Blood. 2003 Apr 1;101(7):2833-41. Epub 2002 Nov 7.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8611683   PMID:16162815   PMID:19946888   PMID:20439489   PMID:22923490   PMID:24449360   PMID:24574022   PMID:25868128   PMID:33198937  


Genomics

Comparative Map Data
Piga
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X33,672,832 - 33,687,747 (-)NCBIGRCr8
mRatBN7.2X30,043,033 - 30,055,861 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX30,042,343 - 30,055,804 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX31,082,324 - 31,095,044 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X34,512,908 - 34,525,604 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X30,706,657 - 30,719,377 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X31,786,823 - 31,799,751 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX31,786,194 - 31,799,560 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X32,160,574 - 32,173,353 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X50,797,413 - 50,812,217 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX30,389,874 - 30,399,559 (-)NCBICelera
Cytogenetic MapXq14NCBI
PIGA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X15,319,451 - 15,335,554 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX15,319,452 - 15,335,554 (-)EnsemblGRCh38hg38GRCh38
GRCh37X15,337,573 - 15,353,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,247,499 - 15,263,581 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX19,453,077 - 19,469,182 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX13,096,081 - 13,112,522 (-)NCBIHuRef
CHM1_1X15,368,527 - 15,384,630 (-)NCBICHM1_1
T2T-CHM13v2.0X14,902,337 - 14,918,440 (-)NCBIT2T-CHM13v2.0
Piga
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X163,202,814 - 163,216,912 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX163,202,783 - 163,216,912 (+)EnsemblGRCm39 Ensembl
GRCm38X164,419,780 - 164,433,916 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX164,419,787 - 164,433,916 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X160,857,719 - 160,871,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X159,763,921 - 159,778,021 (+)NCBIMGSCv36mm8
CeleraX147,635,146 - 147,649,303 (+)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX76.49NCBI
Piga
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555192,852,555 - 2,867,600 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555192,852,605 - 2,865,848 (+)NCBIChiLan1.0ChiLan1.0
PIGA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X17,118,790 - 17,135,672 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X17,122,457 - 17,139,351 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X7,946,158 - 7,962,320 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X15,228,881 - 15,244,949 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX15,228,881 - 15,244,949 (-)Ensemblpanpan1.1panPan2
PIGA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X11,570,327 - 11,583,401 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX11,477,560 - 11,490,558 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X11,532,405 - 11,545,403 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X11,595,315 - 11,608,309 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X11,586,669 - 11,599,667 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X11,614,747 - 11,627,744 (-)NCBIUU_Cfam_GSD_1.0
Piga
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X4,730,960 - 4,747,006 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364704,730,961 - 4,746,985 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364704,730,955 - 4,746,958 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIGA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX11,871,750 - 11,886,438 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X11,871,746 - 11,886,519 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X12,832,314 - 12,847,100 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIGA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X13,787,658 - 13,803,575 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX13,787,646 - 13,803,405 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605615,624,328 - 15,640,151 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Piga
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624829128,586 - 142,150 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624829128,161 - 143,378 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Piga
34 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:19
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000044103
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat

Markers in Region
RH135118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X30,041,048 - 30,041,246 (+)MAPPERmRatBN7.2
Rnor_6.0X31,784,856 - 31,785,053NCBIRnor6.0
Rnor_5.0X32,158,550 - 32,158,747UniSTSRnor5.0
RGSC_v3.4X50,797,532 - 50,797,729UniSTSRGSC3.4
CeleraX30,387,756 - 30,387,953UniSTS
RH 3.4 MapX402.4UniSTS
Cytogenetic MapXq21UniSTS
BF387721  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X30,043,059 - 30,043,250 (+)MAPPERmRatBN7.2
Rnor_6.0X31,786,850 - 31,787,040NCBIRnor6.0
Rnor_5.0X32,160,601 - 32,160,791UniSTSRnor5.0
RGSC_v3.4X50,799,509 - 50,799,699UniSTSRGSC3.4
RGSC_v3.4X50,735,019 - 50,735,209UniSTSRGSC3.4
CeleraX30,389,741 - 30,389,931UniSTS
CeleraX30,325,562 - 30,325,752UniSTS
RH 3.4 MapX422.11UniSTS
Cytogenetic MapXq21UniSTS
PMC22111P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X30,052,270 - 30,052,889 (+)MAPPERmRatBN7.2
Rnor_6.0X31,796,063 - 31,796,681NCBIRnor6.0
Rnor_5.0X32,169,814 - 32,170,432UniSTSRnor5.0
RGSC_v3.4X50,808,722 - 50,809,340UniSTSRGSC3.4
CeleraX30,398,954 - 30,399,572UniSTS
Cytogenetic MapXq21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 6 4 4 4 45 18 26
Low 2 37 53 37 19 37 8 10 29 17 15 11 8
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001842611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001842612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000044103   ⟹   ENSRNOP00000045342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,042,385 - 30,055,804 (-)Ensembl
Rnor_6.0 EnsemblX31,786,194 - 31,799,560 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094241   ⟹   ENSRNOP00000084907
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,051,726 - 30,054,236 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102422   ⟹   ENSRNOP00000097683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,050,122 - 30,055,712 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106938   ⟹   ENSRNOP00000089686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,042,343 - 30,052,876 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107804   ⟹   ENSRNOP00000091008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,051,975 - 30,055,804 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108302   ⟹   ENSRNOP00000087487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,050,122 - 30,055,768 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118152   ⟹   ENSRNOP00000094569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX30,042,351 - 30,055,804 (-)Ensembl
RefSeq Acc Id: NM_001108816   ⟹   NP_001102286
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,675,083 - 33,684,768 (-)NCBI
mRatBN7.2X30,043,193 - 30,052,876 (-)NCBI
Rnor_6.0X31,786,983 - 31,796,668 (-)NCBI
Rnor_5.0X32,160,574 - 32,173,353 (-)NCBI
RGSC_v3.4X50,797,413 - 50,812,217 (-)RGD
CeleraX30,389,874 - 30,399,559 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001401036   ⟹   NP_001387965
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,674,923 - 33,687,617 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,725 (-)NCBI
RefSeq Acc Id: XM_006256870   ⟹   XP_006256932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,011 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,123 (-)NCBI
Rnor_6.0X31,786,823 - 31,799,517 (-)NCBI
Rnor_5.0X32,160,574 - 32,173,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256873   ⟹   XP_006256935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,698 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,861 (-)NCBI
Rnor_6.0X31,786,823 - 31,799,751 (-)NCBI
Rnor_5.0X32,160,574 - 32,173,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256876   ⟹   XP_006256938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,590 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,715 (-)NCBI
Rnor_6.0X31,786,823 - 31,799,517 (-)NCBI
Rnor_5.0X32,160,574 - 32,173,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099874   ⟹   XP_038955802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,746 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,855 (-)NCBI
RefSeq Acc Id: XM_039099875   ⟹   XP_038955803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,611 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,727 (-)NCBI
RefSeq Acc Id: XM_039099876   ⟹   XP_038955804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,747 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,860 (-)NCBI
RefSeq Acc Id: XM_039099879   ⟹   XP_038955807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,616 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,738 (-)NCBI
RefSeq Acc Id: XM_039099880   ⟹   XP_038955808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,686,001 (-)NCBI
mRatBN7.2X30,043,033 - 30,054,110 (-)NCBI
RefSeq Acc Id: XM_039099883   ⟹   XP_038955811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,684,194 (-)NCBI
mRatBN7.2X30,043,033 - 30,052,302 (-)NCBI
RefSeq Acc Id: XM_039099885   ⟹   XP_038955813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,684,525 (-)NCBI
mRatBN7.2X30,043,033 - 30,052,654 (-)NCBI
RefSeq Acc Id: XM_039099886   ⟹   XP_038955814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,745 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,725 (-)NCBI
RefSeq Acc Id: XM_039099888   ⟹   XP_038955816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,653 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,861 (-)NCBI
RefSeq Acc Id: XM_039099889   ⟹   XP_038955817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,513 (-)NCBI
mRatBN7.2X30,043,033 - 30,055,713 (-)NCBI
RefSeq Acc Id: XM_063280127   ⟹   XP_063136197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,484 (-)NCBI
RefSeq Acc Id: XM_063280128   ⟹   XP_063136198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,746 (-)NCBI
RefSeq Acc Id: XM_063280129   ⟹   XP_063136199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,746 (-)NCBI
RefSeq Acc Id: XM_063280130   ⟹   XP_063136200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,675,213 - 33,687,746 (-)NCBI
RefSeq Acc Id: XM_063280131   ⟹   XP_063136201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,679,326 - 33,687,747 (-)NCBI
RefSeq Acc Id: XM_063280132   ⟹   XP_063136202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,745 (-)NCBI
RefSeq Acc Id: XM_063280133   ⟹   XP_063136203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,672,832 - 33,687,745 (-)NCBI
RefSeq Acc Id: XR_005498007
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,679,301 - 33,687,747 (-)NCBI
mRatBN7.2X30,047,411 - 30,055,725 (-)NCBI
RefSeq Acc Id: XR_005498008
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,679,326 - 33,687,747 (-)NCBI
mRatBN7.2X30,047,436 - 30,055,725 (-)NCBI
RefSeq Acc Id: XR_005498009
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,679,301 - 33,687,747 (-)NCBI
mRatBN7.2X30,047,411 - 30,055,725 (-)NCBI
RefSeq Acc Id: XR_005498010
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X33,679,305 - 33,687,747 (-)NCBI
mRatBN7.2X30,047,415 - 30,055,725 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102286 (Get FASTA)   NCBI Sequence Viewer  
  NP_001387965 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256932 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256935 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256938 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955802 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955803 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955804 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955807 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955808 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955811 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955813 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955814 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955816 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955817 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136197 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136198 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136199 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136200 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136201 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136202 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136203 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL90522 (Get FASTA)   NCBI Sequence Viewer  
  EDL90523 (Get FASTA)   NCBI Sequence Viewer  
  EDL90524 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045342
  ENSRNOP00000045342.4
  ENSRNOP00000084907.1
  ENSRNOP00000087487.1
  ENSRNOP00000089686.1
  ENSRNOP00000091008.1
  ENSRNOP00000094569.1
  ENSRNOP00000097683.1
RefSeq Acc Id: NP_001102286   ⟸   NM_001108816
- Peptide Label: isoform 2
- UniProtKB: A6K2K6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256935   ⟸   XM_006256873
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256938   ⟸   XM_006256876
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256932   ⟸   XM_006256870
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000045342   ⟸   ENSRNOT00000044103
RefSeq Acc Id: XP_038955816   ⟸   XM_039099888
- Peptide Label: isoform X5
- UniProtKB: A6K2K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955804   ⟸   XM_039099876
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955802   ⟸   XM_039099874
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955807   ⟸   XM_039099879
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955803   ⟸   XM_039099875
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955814   ⟸   XM_039099886
- Peptide Label: isoform X5
- UniProtKB: A6K2K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955817   ⟸   XM_039099889
- Peptide Label: isoform X5
- UniProtKB: A6K2K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955808   ⟸   XM_039099880
- Peptide Label: isoform X1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955813   ⟸   XM_039099885
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038955811   ⟸   XM_039099883
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000089686   ⟸   ENSRNOT00000106938
RefSeq Acc Id: ENSRNOP00000097683   ⟸   ENSRNOT00000102422
RefSeq Acc Id: ENSRNOP00000091008   ⟸   ENSRNOT00000107804
RefSeq Acc Id: ENSRNOP00000094569   ⟸   ENSRNOT00000118152
RefSeq Acc Id: ENSRNOP00000084907   ⟸   ENSRNOT00000094241
RefSeq Acc Id: ENSRNOP00000087487   ⟸   ENSRNOT00000108302
RefSeq Acc Id: NP_001387965   ⟸   NM_001401036
- Peptide Label: isoform 1
- UniProtKB: D4AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136199   ⟸   XM_063280129
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136198   ⟸   XM_063280128
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136203   ⟸   XM_063280133
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063136202   ⟸   XM_063280132
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063136197   ⟸   XM_063280127
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136200   ⟸   XM_063280130
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063136201   ⟸   XM_063280131
- Peptide Label: isoform X3
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAY7-F1-model_v2 AlphaFold D4AAY7 1-485 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701795
Promoter ID:EPDNEW_R12319
Type:single initiation site
Name:Piga_1
Description:phosphatidylinositol glycan anchor biosynthesis, class A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X31,799,546 - 31,799,606EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589723 AgrOrtholog
BioCyc Gene G2FUF-2594 BioCyc
Ensembl Genes ENSRNOG00000003554 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044103.6 UniProtKB/TrEMBL
  ENSRNOT00000094241.1 UniProtKB/TrEMBL
  ENSRNOT00000102422.1 UniProtKB/TrEMBL
  ENSRNOT00000106938.1 UniProtKB/TrEMBL
  ENSRNOT00000107804.1 UniProtKB/TrEMBL
  ENSRNOT00000108302.1 UniProtKB/TrEMBL
  ENSRNOT00000118152.1 UniProtKB/TrEMBL
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/TrEMBL
InterPro Glyco_trans_1 UniProtKB/TrEMBL
  PIG-A/GPI3 UniProtKB/TrEMBL
  PIGA_GPI_anchor_biosynthesis UniProtKB/TrEMBL
KEGG Report rno:363464 UniProtKB/TrEMBL
NCBI Gene 363464 ENTREZGENE
PANTHER N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN UniProtKB/TrEMBL
  PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A UniProtKB/TrEMBL
Pfam Glycos_transf_1 UniProtKB/TrEMBL
  PIGA UniProtKB/TrEMBL
PhenoGen Piga PhenoGen
RatGTEx ENSRNOG00000003554 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/TrEMBL
UniProt A0A8I6A8P6_RAT UniProtKB/TrEMBL
  A0A8I6ADP6_RAT UniProtKB/TrEMBL
  A0A8I6AMH9_RAT UniProtKB/TrEMBL
  A6K2K6 ENTREZGENE, UniProtKB/TrEMBL
  A6K2K7_RAT UniProtKB/TrEMBL
  A6K2K8_RAT UniProtKB/TrEMBL
  D4AAY7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Piga  phosphatidylinositol glycan anchor biosynthesis, class A  Piga  phosphatidylinositol glycan, class A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   phosphatidylinositol glycan, class A  Piga  phosphatidylinositol glycan, class A (mapped)  Name updated 737654 APPROVED
2007-04-11 Piga  phosphatidylinositol glycan, class A (mapped)  Piga_mapped  phosphatidylinositol glycan, class A (mapped)  Data merged from RGD:3327 737654 APPROVED
2006-11-19 Piga  phosphatidylinositol glycan, class A (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Piga_mapped  phosphatidylinositol glycan, class A (mapped)  Piga  phosphatidylinositol glycan, class A  Symbol and Name updated 1556543 APPROVED
2002-06-10 Piga  Phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) = N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein      Symbol and Name status set to approved 70586 APPROVED