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Gene: Atp6v1a (ATPase H+ transporting V1 subunit A) Rattus norvegicus
Symbol: Atp6v1a
Name: ATPase H+ transporting V1 subunit A
Description: Predicted to have proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular iron ion homeostasis and cellular response to increased oxygen levels. Predicted to localize to several cellular components, including apical plasma membrane; microvillus; and vacuolar membrane. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and childhood onset epileptic encephalopathy. Orthologous to human ATP6V1A (ATPase H+ transporting V1 subunit A); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,2,2-tetramine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Atp6v1a1; ATPase, H+ transporting, lysosomal V1 subunit A; LOC685232; similar to ATPase, H+ transporting, V1 subunit A, isoform 1; V-type proton ATPase catalytic subunit A
Homo sapiens (human) : ATP6V1A (ATPase H+ transporting V1 subunit A)  HGNC  Alliance
Mus musculus (house mouse) : Atp6v1a (ATPase, H+ transporting, lysosomal V1 subunit A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp6v1a (ATPase H+ transporting V1 subunit A)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP6V1A (ATPase H+ transporting V1 subunit A)
Canis lupus familiaris (dog) : ATP6V1A (ATPase H+ transporting V1 subunit A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp6v1a (ATPase H+ transporting V1 subunit A)
Sus scrofa (pig) : ATP6V1A (ATPase H+ transporting V1 subunit A)
Chlorocebus sabaeus (African green monkey) : ATP6V1A (ATPase H+ transporting V1 subunit A)
Heterocephalus glaber (naked mole-rat) : Atp6v1a (ATPase H+ transporting V1 subunit A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01161,531,386 - 61,584,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1161,531,416 - 61,584,634 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01165,638,315 - 65,691,322 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,127,307 - 58,180,225 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1156,114,743 - 56,167,820 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Atp6v1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1596464
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.