Atp6v1a (ATPase H+ transporting V1 subunit A) - Rat Genome Database

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Gene: Atp6v1a (ATPase H+ transporting V1 subunit A) Rattus norvegicus
Analyze
Symbol: Atp6v1a
Name: ATPase H+ transporting V1 subunit A
RGD ID: 1596464
Description: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular response to increased oxygen levels; intracellular iron ion homeostasis; and synaptic vesicle lumen acidification. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Orthologous to human ATP6V1A (ATPase H+ transporting V1 subunit A); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,2,2-tetramine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Atp6v1a1; ATPase, H+ transporting, lysosomal V1 subunit A; LOC685232; similar to ATPase, H+ transporting, V1 subunit A, isoform 1; V-type proton ATPase catalytic subunit A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Atp6v1a-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81170,066,800 - 70,120,603 (+)NCBIGRCr8
mRatBN7.21156,561,444 - 56,614,694 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,560,974 - 56,614,694 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1165,374,765 - 65,427,862 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01158,037,002 - 58,090,109 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01157,085,748 - 57,138,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01161,531,386 - 61,584,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1161,531,416 - 61,584,634 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01165,638,315 - 65,691,322 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,127,307 - 58,180,225 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1156,114,743 - 56,167,820 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
3-chloropropane-1,2-diol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (EXP)
butylated hydroxyanisole  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
etoposide  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
ginsenoside Rb1  (ISO)
indometacin  (EXP)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
manganese(II) chloride  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
omeprazole  (EXP)
paclitaxel  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (ISO)
propiconazole  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sulindac  (EXP)
T-2 toxin  (EXP)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
thioacetamide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structure of V-ATPase from the mammalian brain. Abbas YM, etal., Science. 2020 Mar 13;367(6483):1240-1246. doi: 10.1126/science.aaz2924.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14651853   PMID:15632090   PMID:16177003   PMID:17634366   PMID:17897319   PMID:18667600   PMID:19056867   PMID:19199708   PMID:20169059   PMID:20458337   PMID:21700703   PMID:22871113  
PMID:23376485   PMID:23533145   PMID:28296633   PMID:29604406  


Genomics

Comparative Map Data
Atp6v1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81170,066,800 - 70,120,603 (+)NCBIGRCr8
mRatBN7.21156,561,444 - 56,614,694 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,560,974 - 56,614,694 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1165,374,765 - 65,427,862 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01158,037,002 - 58,090,109 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01157,085,748 - 57,138,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01161,531,386 - 61,584,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1161,531,416 - 61,584,634 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01165,638,315 - 65,691,322 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,127,307 - 58,180,225 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1156,114,743 - 56,167,820 (+)NCBICelera
Cytogenetic Map11q21NCBI
ATP6V1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383113,747,035 - 113,812,056 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3113,746,770 - 113,812,056 (+)EnsemblGRCh38hg38GRCh38
GRCh373113,465,882 - 113,530,903 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363114,948,598 - 115,013,593 (+)NCBINCBI36Build 36hg18NCBI36
Build 343114,948,597 - 115,013,591NCBI
Celera3111,874,398 - 111,939,560 (+)NCBICelera
Cytogenetic Map3q13.31NCBI
HuRef3110,840,759 - 110,905,622 (+)NCBIHuRef
CHM1_13113,429,223 - 113,494,222 (+)NCBICHM1_1
T2T-CHM13v2.03116,467,516 - 116,533,252 (+)NCBIT2T-CHM13v2.0
Atp6v1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391643,905,765 - 43,960,055 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1643,905,765 - 43,960,068 (-)EnsemblGRCm39 Ensembl
GRCm381644,085,402 - 44,139,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1644,085,402 - 44,139,705 (-)EnsemblGRCm38mm10GRCm38
MGSCv371644,085,517 - 44,139,132 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361644,006,117 - 44,058,329 (-)NCBIMGSCv36mm8
Celera1644,440,632 - 44,496,218 (-)NCBICelera
Cytogenetic Map16B4NCBI
cM Map1628.44NCBI
Atp6v1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542713,868,171 - 13,922,028 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542713,868,683 - 13,922,028 (+)NCBIChiLan1.0ChiLan1.0
ATP6V1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22111,741,923 - 111,805,646 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13111,746,707 - 111,810,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03110,888,504 - 110,951,750 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13117,808,963 - 117,872,349 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3117,808,963 - 117,872,349 (+)Ensemblpanpan1.1panPan2
ATP6V1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13318,038,143 - 18,103,649 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3318,038,801 - 18,101,435 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3318,140,143 - 18,205,535 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03318,282,343 - 18,349,714 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3318,282,567 - 18,349,714 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13318,086,053 - 18,153,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03318,133,128 - 18,198,487 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03318,684,569 - 18,750,022 (+)NCBIUU_Cfam_GSD_1.0
Atp6v1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602136,207,141 - 136,264,040 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365361,257,990 - 1,312,530 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365361,257,801 - 1,314,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP6V1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13146,121,759 - 146,192,442 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113146,128,664 - 146,165,269 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213155,713,931 - 155,750,535 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP6V1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12267,049,745 - 67,112,971 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2267,048,796 - 67,081,962 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604199,356,934 - 99,419,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp6v1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473134,721,142 - 34,780,632 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp6v1a
281 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:300
Count of miRNA genes:174
Interacting mature miRNAs:229
Transcripts:ENSRNOT00000002727
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat

Markers in Region
RH127473  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22153,926,571 - 153,926,781 (+)MAPPERmRatBN7.2
mRatBN7.21156,614,354 - 56,614,565 (-)MAPPERmRatBN7.2
mRatBN7.21156,614,354 - 56,614,565 (+)MAPPERmRatBN7.2
Rnor_6.01161,584,295 - 61,584,505NCBIRnor6.0
Rnor_6.02166,315,993 - 166,316,202NCBIRnor6.0
Rnor_5.01165,690,983 - 65,691,193UniSTSRnor5.0
Rnor_5.02185,672,845 - 185,673,054UniSTSRnor5.0
RGSC_v3.42159,758,566 - 159,758,775UniSTSRGSC3.4
RGSC_v3.41158,179,886 - 58,180,096UniSTSRGSC3.4
Celera1156,167,481 - 56,167,691UniSTS
Celera2148,272,967 - 148,273,176UniSTS
RH 3.4 Map21005.2UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic Map11q21UniSTS
RH141877  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21156,612,691 - 56,612,897 (-)MAPPERmRatBN7.2
mRatBN7.21156,612,691 - 56,612,897 (+)MAPPERmRatBN7.2
mRatBN7.22153,928,241 - 153,928,447 (-)MAPPERmRatBN7.2
mRatBN7.22153,928,241 - 153,928,447 (+)MAPPERmRatBN7.2
Rnor_6.02166,317,663 - 166,317,868NCBIRnor6.0
Rnor_6.01161,582,632 - 61,582,837NCBIRnor6.0
Rnor_5.02185,674,515 - 185,674,720UniSTSRnor5.0
Rnor_5.01165,689,320 - 65,689,525UniSTSRnor5.0
RGSC_v3.42159,760,236 - 159,760,441UniSTSRGSC3.4
RGSC_v3.41158,178,223 - 58,178,428UniSTSRGSC3.4
Celera1156,165,895 - 56,166,100UniSTS
Celera2148,274,637 - 148,274,842UniSTS
RH 3.4 Map21004.9UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic Map11q21UniSTS
Atp6v1a  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21156,598,094 - 56,598,324 (+)MAPPERmRatBN7.2
mRatBN7.22153,929,233 - 153,929,380 (+)MAPPERmRatBN7.2
Rnor_6.02166,318,655 - 166,318,801NCBIRnor6.0
Rnor_6.01161,568,037 - 61,568,266NCBIRnor6.0
Rnor_5.01165,674,725 - 65,674,954UniSTSRnor5.0
Rnor_5.02185,675,507 - 185,675,653UniSTSRnor5.0
RGSC_v3.42159,761,228 - 159,761,374UniSTSRGSC3.4
RGSC_v3.41158,163,628 - 58,163,857UniSTSRGSC3.4
Celera1156,151,300 - 56,151,529UniSTS
Celera2148,275,629 - 148,275,775UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic Map11q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 57 41 19 41 2 2 74 35 38 11 2
Low 8 6 9 3 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000002727   ⟹   ENSRNOP00000002727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1156,560,974 - 56,614,691 (+)Ensembl
Rnor_6.0 Ensembl1161,531,578 - 61,584,634 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093263   ⟹   ENSRNOP00000076339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1161,531,416 - 61,558,785 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093467   ⟹   ENSRNOP00000076121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1156,584,015 - 56,614,694 (+)Ensembl
Rnor_6.0 Ensembl1161,531,571 - 61,584,634 (+)Ensembl
RefSeq Acc Id: NM_001108318   ⟹   NP_001101788
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81170,067,502 - 70,120,603 (+)NCBI
mRatBN7.21156,561,590 - 56,614,694 (+)NCBI
Rnor_6.01161,531,578 - 61,584,634 (+)NCBI
Rnor_5.01165,638,315 - 65,691,322 (+)NCBI
RGSC_v3.41158,127,307 - 58,180,225 (+)RGD
Celera1156,114,743 - 56,167,820 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248348   ⟹   XP_006248410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81170,067,307 - 70,120,603 (+)NCBI
mRatBN7.21156,561,457 - 56,614,679 (+)NCBI
Rnor_6.01161,531,559 - 61,584,229 (+)NCBI
Rnor_5.01165,638,315 - 65,691,322 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248349   ⟹   XP_006248411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81170,067,345 - 70,120,603 (+)NCBI
mRatBN7.21156,561,457 - 56,614,679 (+)NCBI
Rnor_6.01161,531,386 - 61,584,634 (+)NCBI
Rnor_5.01165,638,315 - 65,691,322 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063270767   ⟹   XP_063126837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81170,066,800 - 70,120,603 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101788 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248410 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248411 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126837 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM11168 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002727
  ENSRNOP00000002727.6
  ENSRNOP00000076121.2
RefSeq Acc Id: NP_001101788   ⟸   NM_001108318
- UniProtKB: A6IR15 (UniProtKB/TrEMBL),   A0A1W2Q641 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248410   ⟸   XM_006248348
- Peptide Label: isoform X1
- UniProtKB: A6IR15 (UniProtKB/TrEMBL),   A0A1W2Q641 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248411   ⟸   XM_006248349
- Peptide Label: isoform X1
- UniProtKB: A6IR15 (UniProtKB/TrEMBL),   A0A1W2Q641 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002727   ⟸   ENSRNOT00000002727
RefSeq Acc Id: ENSRNOP00000076121   ⟸   ENSRNOT00000093467
RefSeq Acc Id: ENSRNOP00000076339   ⟸   ENSRNOT00000093263
RefSeq Acc Id: XP_063126837   ⟸   XM_063270767
- Peptide Label: isoform X1
- UniProtKB: A0A1W2Q641 (UniProtKB/TrEMBL),   A6IR15 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A133-F1-model_v2 AlphaFold D4A133 1-617 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698152
Promoter ID:EPDNEW_R8677
Type:initiation region
Name:Atp6v1a_1
Description:ATPase H+ transporting V1 subunit A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01161,531,611 - 61,531,671EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596464 AgrOrtholog
BioCyc Gene G2FUF-21340 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000001992 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002727 ENTREZGENE
  ENSRNOT00000002727.6 UniProtKB/TrEMBL
  ENSRNOT00000093467.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.30.20 UniProtKB/TrEMBL
  2.40.50.100 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro ATP-synt_a_Xtn UniProtKB/TrEMBL
  ATP_synth_asu-like_sf UniProtKB/TrEMBL
  ATPase_a/bsu_AS UniProtKB/TrEMBL
  ATPase_a/bsu_nucl-bd UniProtKB/TrEMBL
  ATPase_F1/V1/A1-cplx_a/bsu_N UniProtKB/TrEMBL
  ATPase_F1/V1/A1_a/bsu_N_sf UniProtKB/TrEMBL
  ATPase_F1_bsu/V1_C UniProtKB/TrEMBL
  ATPase_V1-cplx_asu UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  V-ATPase_su_A/alpha UniProtKB/TrEMBL
KEGG Report rno:685232 UniProtKB/TrEMBL
NCBI Gene 685232 ENTREZGENE
PANTHER PTHR43607 UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A UniProtKB/TrEMBL
Pfam ATP-synt_ab UniProtKB/TrEMBL
  ATP-synt_ab_N UniProtKB/TrEMBL
  ATP-synt_ab_Xtn UniProtKB/TrEMBL
PhenoGen Atp6v1a PhenoGen
PROSITE ATPASE_ALPHA_BETA UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001992 RatGTEx
Superfamily-SCOP ATPase_a/b_N UniProtKB/TrEMBL
  C-terminal domain of alpha and beta subunits of F1 ATP synthase UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A1W2Q641 ENTREZGENE, UniProtKB/TrEMBL
  A6IR15 ENTREZGENE, UniProtKB/TrEMBL
  D4A133_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Atp6v1a  ATPase H+ transporting V1 subunit A  Atp6v1a  ATPase, H+ transporting, lysosomal V1 subunit A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Atp6v1a  ATPase, H+ transporting, lysosomal V1 subunit A  LOC685232  similar to ATPase, H+ transporting, V1 subunit A, isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC685232  similar to ATPase, H+ transporting, V1 subunit A, isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL