Bp187 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp187 (Blood pressure QTL 187) Rattus norvegicus

Symbol: Bp187
Name: Blood pressure QTL 187
RGD ID: 1300147
Previously known as: Specialized Center of Research QTL 47, 110; SCOR47; SCOR110
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: blood pressure time series experimental set point of the baroreceptor response   (CMO:0002593)    
LOD Score: 3.67
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81122,524,746 - 82,951,192RGD_MAPPER_PIPELINE
mRatBN7.2111 - 69,446,234RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0111 - 72,720,192RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01111,251,738 - 75,797,949RGDRnor5.0
RGSC_v3.4119,053,659 - 50,435,443RGDRGSC3.4
RGSC_v3.1119,053,659 - 50,435,385RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187Rathypertension  IDA 727992 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187Ratincreased systemic arterial blood pressure  QTM 727992 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187Ratblood pressure time series experimental set point of the baroreceptor response  IDA 727992 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187Ratcontrolled sodium content diet  IDA 727992 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187Ratvascular indwelling catheter method  IDA 727992 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187RatBN/SsNHsd  IEA 727992 RGD 
Bp187RatSS/JrHsdMcwi  IEA 727992 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp187Ratarterial blood pressure trait  IDA 727992 RGD 


#
Reference Title
Reference Citation
1. Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Moreno C, etal., Physiol Genomics 2003 Nov 11;15(3):243-57. Epub 2003 Oct 07.


1 to 20 of 763 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41216714LOC1200930615.8S ribosomal RNA116296363115Rat
1584979Arl13bARF like GTPase 13B11150100217103Rat
1597703Stx19syntaxin 1911172855178053Rat
620971Pros1protein S11230597311288Rat
1584978Slc22a7-ps1solute carrier family 22 (organic anion transporter), member 7, pseudogene 111351938353606Rat
41064937LOC120095789U2 spliceosomal RNA11445023445186Rat
6494940Npm1-ps21nucleophosmin 1, pseudogene 211110765391077949Rat
41141637LOC120095801U4 spliceosomal RNA1111382101138385Rat
68389Epha3Eph receptor A31111384851474102Rat
41323621LOC120095722U7 small nuclear RNA1115517401551802Rat
41065123LOC120095723U7 small nuclear RNA1115518841551945Rat
1562102Csnk2a2ipcasein kinase 2 subunit alpha' interacting protein1121275532253399Rat
41113800LOC120095814U6 spliceosomal RNA1121603382160441Rat
1586142Atp5mg-ps6ATP synthase membrane subunit g, pseudogene 61124405312440945Rat
1359320C11h3orf38similar to human chromosome 3 open reading frame 381124839832488631Rat
1308321Zfp654zinc finger protein 6541125008922565552Rat
1308129Cggbp1CGG triplet repeat binding protein 11125656292572869Rat
1584835Polr2e-ps1RNA polymerase II, I and III subunit E, pseudogene 11125738802574980Rat
71083Htr1f5-hydroxytryptamine receptor 1F1126427512644150Rat
41063307LOC120095588uncharacterized LOC1200955881127737902827981Rat

1 to 20 of 763 rows
1 to 20 of 947 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10911D11Wox3184115543703355437217Ratregion
11026D11Wox9153113708449637084649Ratregion
33792D11Mit2262113015999530160257Ratregion
33899D11Mit494112183661521836709Ratregion
34003D11Mit3134112627791326278047Ratregion
34112D11Mgh4172115980262259802794Ratregion
34130D11Mgh6100111897620818976310Ratregion
34725D11Mgh3168116642214866422316Ratregion
34727D11Mgh9147116297952662979675Ratregion
33642D11Mit1123113491804134918164Ratregion
33642D11Mit1123113491804134918164Ratregion
35989D11Rat29145111342715713427302Ratregion
35989D11Rat29145111342715713427540Ratregion
36065D11Rat6152114428575944285911Ratregion
36095D11Rat7161114545932345459484Ratregion
36281D11Rat4167116279034262790509Ratregion
36342D11Mit9256115938586459386120Ratregion
36346D11Mit10229113283509832835327Ratregion
37516D11Rat39202113714899437149196Ratregion
37574D11Rat521611164028516403014Ratregion
1 to 20 of 947 rows

Flank 1: (D11Rat22)
Rat AssemblyChrPosition (strand)Source
GRCr81122,524,746 - 22,524,902 (+)Marker Load Pipeline
Rnor_5.01111,251,739 - 11,251,899NCBI
Rnor_5.01111,251,738 - 11,251,899NCBI
RGSC_v3.4119,053,659 - 9,053,815RGD
RGSC_v3.4119,053,660 - 9,053,815UniSTS
RGSC_v3.1119,053,659 - 9,053,815RGD
Celera119,002,538 - 9,002,685UniSTS
RH 3.4 Map1149.8UniSTS
RH 3.4 Map1149.8RGD
RH 2.0 Map11719.3RGD
Peak: (D11Rat15)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21129,528,418 - 29,528,587 (+)MAPPER
Rnor_6.01130,435,339 - 30,435,507NCBI
Rnor_5.01134,054,821 - 34,054,989UniSTS
RGSC_v3.41129,744,438 - 29,744,606UniSTS
RGSC_v3.41129,744,366 - 29,744,736RGD
RGSC_v3.11129,744,438 - 29,744,606RGD
Celera1129,215,379 - 29,215,547UniSTS
RH 3.4 Map11167.8RGD
RH 3.4 Map11167.8UniSTS
RH 2.0 Map11469.5RGD
SHRSP x BN Map118.2299RGD
FHH x ACI Map1112.19RGD
Cytogenetic Map11q11UniSTS
Flank 2: (D11Rat61)
Rat AssemblyChrPosition (strand)Source
GRCr81182,951,028 - 82,951,192 (+)Marker Load Pipeline
mRatBN7.21169,446,070 - 69,446,234 (+)MAPPER
Rnor_6.01172,720,029 - 72,720,192NCBI
Rnor_5.01175,797,786 - 75,797,949UniSTS
Celera1168,866,233 - 68,866,396UniSTS
SHRSP x BN Map1133.2098RGD
SHRSP x BN Map1133.2098UniSTS
Cytogenetic Map11q11UniSTS


1 to 10 of 36 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111897620824697116Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat

1 to 10 of 36 rows


Database
Acc Id
Source(s)
NCBI Gene Bp187

Note Type Note Reference
qtl_general significant linkage also found at this locus to the change between the peak and control mean arterial pressure (SCOR110, LOD=2.81) 727992
qtl_general time series calculations are derived from the parameters related to the set points and gains of the baroreflex control system 727992
qtl_general additional information, including phenotype and mapping information, can be found at Genomic Map of Cardiovascular Phenotypes 727992