Cxadr (CXADR, Ig-like cell adhesion molecule) - Rat Genome Database

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Gene: Cxadr (CXADR, Ig-like cell adhesion molecule) Rattus norvegicus
Analyze
Symbol: Cxadr
Name: CXADR, Ig-like cell adhesion molecule
RGD ID: 619794
Description: Predicted to enable several functions, including PDZ domain binding activity; beta-catenin binding activity; and connexin binding activity. Predicted to be involved in several processes, including AV node cell-bundle of His cell adhesion involved in cell communication; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and neutrophil chemotaxis. Predicted to act upstream of or within negative regulation of cardiac muscle cell proliferation. Located in bicellular tight junction and neuron projection. Orthologous to human CXADR (CXADR Ig-like cell adhesion molecule); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CAR; Car1; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor homolog; MGC109536; rCAR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21116,982,752 - 17,030,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1116,982,860 - 17,030,046 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1125,620,930 - 25,668,242 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01118,350,955 - 18,398,261 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01117,511,443 - 17,559,008 (+)NCBIRnor_WKY
Rnor_6.01116,826,269 - 16,873,564 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,826,399 - 16,873,562 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01120,480,930 - 20,528,211 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41117,193,505 - 17,241,549 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11117,193,575 - 17,227,857 (+)NCBI
Celera1116,973,781 - 17,020,940 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bosentan  (ISO)
butanal  (ISO)
butyric acid  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (ISO)
clothianidin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enniatin  (EXP)
epoxiconazole  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
mifepristone  (EXP)
mitoxantrone  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
potassium iodide  (EXP)
propiconazole  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rimonabant  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers. Fechner H, etal., Gene Ther 1999 Sep;6(9):1520-35.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Coxsackievirus and adenovirus receptor, a tight junction membrane protein, is expressed in glomerular podocytes in the kidney. Nagai M, etal., Lab Invest 2003 Jun;83(6):901-11.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. CAR-associated vesicular transport of an adenovirus in motor neuron axons. Salinas S, etal., PLoS Pathog. 2009 May;5(5):e1000442. doi: 10.1371/journal.ppat.1000442. Epub 2009 May 22.
10. Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes. Shono A, etal., J Am Soc Nephrol. 2007 Sep;18(9):2525-33. Epub 2007 Aug 5.
Additional References at PubMed
PMID:9096397   PMID:10814828   PMID:11316797   PMID:11734628   PMID:12297051   PMID:12477932   PMID:12869515   PMID:14624362   PMID:14978041   PMID:15057822   PMID:15304526   PMID:15364909  
PMID:15489334   PMID:15533241   PMID:15800062   PMID:15864812   PMID:16079292   PMID:16410001   PMID:16543498   PMID:16678988   PMID:16780588   PMID:17359973   PMID:17538635   PMID:17690169  
PMID:18205224   PMID:18636119   PMID:20235596   PMID:20361046   PMID:20813954   PMID:21269662   PMID:22003382   PMID:22875787   PMID:24057874   PMID:25468996   PMID:25497012  


Genomics

Comparative Map Data
Cxadr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21116,982,752 - 17,030,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1116,982,860 - 17,030,046 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1125,620,930 - 25,668,242 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01118,350,955 - 18,398,261 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01117,511,443 - 17,559,008 (+)NCBIRnor_WKY
Rnor_6.01116,826,269 - 16,873,564 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,826,399 - 16,873,562 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01120,480,930 - 20,528,211 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41117,193,505 - 17,241,549 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11117,193,575 - 17,227,857 (+)NCBI
Celera1116,973,781 - 17,020,940 (+)NCBICelera
Cytogenetic Map11q11NCBI
CXADR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382117,513,043 - 17,636,262 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2117,513,043 - 17,593,579 (+)EnsemblGRCh38hg38GRCh38
GRCh372118,885,361 - 18,965,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362117,807,201 - 17,861,147 (+)NCBINCBI36Build 36hg18NCBI36
Build 342117,807,200 - 17,861,135NCBI
Celera214,060,105 - 4,114,040 (+)NCBICelera
Cytogenetic Map21q21.1NCBI
HuRef214,271,028 - 4,351,637 (+)NCBIHuRef
CHM1_12118,445,887 - 18,526,468 (+)NCBICHM1_1
T2T-CHM13v2.02115,868,092 - 15,948,630 (+)NCBIT2T-CHM13v2.0
Cxadr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391678,098,114 - 78,156,673 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1678,098,377 - 78,156,662 (+)EnsemblGRCm39 Ensembl
GRCm381678,301,226 - 78,359,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1678,301,489 - 78,359,774 (+)EnsemblGRCm38mm10GRCm38
MGSCv371678,301,936 - 78,360,030 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361678,184,283 - 78,223,344 (+)NCBIMGSCv36mm8
Celera1678,531,603 - 78,582,585 (+)NCBICelera
Cytogenetic Map16C3.1NCBI
Cxadr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540718,867,797 - 18,907,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540718,894,853 - 18,927,129 (+)NCBIChiLan1.0ChiLan1.0
CXADR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12117,637,510 - 17,693,324 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2117,636,952 - 17,693,324 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0214,246,779 - 4,367,369 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CXADR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13114,021,292 - 14,079,049 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3114,021,303 - 14,078,847 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3114,040,422 - 14,099,214 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03114,054,721 - 14,113,513 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3114,055,183 - 14,113,306 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13114,057,180 - 14,115,931 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03114,060,916 - 14,121,453 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03114,461,638 - 14,520,275 (+)NCBIUU_Cfam_GSD_1.0
Cxadr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497115,051,698 - 15,094,341 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365059,971,118 - 10,032,238 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365059,971,393 - 10,032,238 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXADR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13182,134,566 - 182,185,950 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113182,134,416 - 182,185,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213192,284,884 - 192,305,700 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXADR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1275,027,499 - 75,078,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl275,001,562 - 75,078,033 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605078,908,252 - 78,986,846 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cxadr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247455,900,886 - 5,958,765 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247455,900,933 - 5,954,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cxadr
368 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:47
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000050701
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)11121836709Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111283104625121472Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat

Markers in Region
RH137702  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21117,020,309 - 17,020,525 (+)MAPPERmRatBN7.2
Rnor_6.01116,863,796 - 16,864,011NCBIRnor6.0
Rnor_5.01120,518,443 - 20,518,658UniSTSRnor5.0
RGSC_v3.41117,231,781 - 17,231,996UniSTSRGSC3.4
Celera1117,011,172 - 17,011,387UniSTS
RH 3.4 Map1165.2UniSTS
Cytogenetic Map11q11UniSTS
AU049654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21117,014,818 - 17,014,969 (+)MAPPERmRatBN7.2
Rnor_6.01116,858,308 - 16,858,458NCBIRnor6.0
Rnor_5.01120,512,955 - 20,513,105UniSTSRnor5.0
RGSC_v3.41117,226,292 - 17,226,442UniSTSRGSC3.4
Celera1117,005,683 - 17,005,833UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 39 37 37 4 37 74 34 33 11
Low 1 4 20 4 15 4 8 10 1 8 8
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000050701   ⟹   ENSRNOP00000041873
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1116,982,860 - 17,030,046 (+)Ensembl
Rnor_6.0 Ensembl1116,826,399 - 16,873,562 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094570   ⟹   ENSRNOP00000091602
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1116,982,860 - 17,009,467 (+)Ensembl
RefSeq Acc Id: NM_053570   ⟹   NP_446022
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21116,982,913 - 17,030,078 (+)NCBI
Rnor_6.01116,826,399 - 16,873,564 (+)NCBI
Rnor_5.01120,480,930 - 20,528,211 (+)NCBI
RGSC_v3.41117,193,505 - 17,241,549 (+)RGD
Celera1116,973,781 - 17,020,940 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248000   ⟹   XP_006248062
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21116,982,752 - 17,020,626 (+)NCBI
Rnor_6.01116,826,269 - 16,864,106 (+)NCBI
Rnor_5.01120,480,930 - 20,528,211 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_446022   ⟸   NM_053570
- Peptide Label: precursor
- UniProtKB: Q9R066 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248062   ⟸   XM_006248000
- Peptide Label: isoform X1
- UniProtKB: Q9R066 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041873   ⟸   ENSRNOT00000050701
RefSeq Acc Id: ENSRNOP00000091602   ⟸   ENSRNOT00000094570
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R066-F1-model_v2 AlphaFold Q9R066 1-365 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698007
Promoter ID:EPDNEW_R8532
Type:initiation region
Name:Cxadr_1
Description:CXADR, Ig-like cell adhesion molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01116,826,386 - 16,826,446EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619794 AgrOrtholog
BioCyc Gene G2FUF-22139 BioCyc
Ensembl Genes ENSRNOG00000001557 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041873 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000091602.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050701 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000094570.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7324723 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot
KEGG Report rno:89843 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109536 IMAGE-MGC_LOAD
NCBI Gene 89843 ENTREZGENE
Pfam PF00047 UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cxadr PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AST4_RAT UniProtKB/TrEMBL
  CXAR_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9R067 ENTREZGENE
UniProt Secondary Q5M817 UniProtKB/Swiss-Prot
  Q9R067 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-05 Cxadr  CXADR, Ig-like cell adhesion molecule  Cxadr  coxsackie virus and adenovirus receptor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cxadr  coxsackie virus and adenovirus receptor      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cxadr  coxsackie virus and adenovirus receptor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in podocytes and polarized epithelial cells 1299248
gene_function may be a barrier for macromolecule and ion movement across membranes in polarized epithelial cells 1299248