Or5k17 (olfactory receptor family 5 subfamily K member 17) - Rat Genome Database

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Gene: Or5k17 (olfactory receptor family 5 subfamily K member 17) Rattus norvegicus
Analyze
Symbol: Or5k17 (Ensembl: Or5k15)
Name: olfactory receptor family 5 subfamily K member 17 (Ensembl:olfactory receptor family 5 subfamily K member 15)
RGD ID: 1333626
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR5K4 (olfactory receptor family 5 subfamily K member 4); INTERACTS WITH glyphosate; 1,2-dichloroethane (ortholog); 2-palmitoylglycerol (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1558; olfactory receptor gene Olr1558; olfactory receptor Olr1558; Olr1558
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81155,057,993 - 55,058,946 (+)NCBIGRCr8
mRatBN7.21141,588,795 - 41,589,748 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1141,584,852 - 41,590,142 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1150,322,184 - 50,323,137 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01142,993,481 - 42,994,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01142,122,121 - 42,123,074 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01143,687,107 - 43,688,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,687,107 - 43,688,054 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01146,872,266 - 46,873,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41142,395,097 - 42,396,050 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11142,452,685 - 42,453,639 (+)NCBI
Celera1141,392,184 - 41,393,137 (+)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or5k17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81155,057,993 - 55,058,946 (+)NCBIGRCr8
mRatBN7.21141,588,795 - 41,589,748 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1141,584,852 - 41,590,142 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1150,322,184 - 50,323,137 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01142,993,481 - 42,994,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01142,122,121 - 42,123,074 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01143,687,107 - 43,688,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,687,107 - 43,688,054 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01146,872,266 - 46,873,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41142,395,097 - 42,396,050 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11142,452,685 - 42,453,639 (+)NCBI
Celera1141,392,184 - 41,393,137 (+)NCBICelera
Cytogenetic Map11q12NCBI
OR5K4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38398,353,854 - 98,354,819 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl398,353,854 - 98,354,819 (+)EnsemblGRCh38hg38GRCh38
GRCh37398,072,698 - 98,073,663 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36399,555,388 - 99,556,353 (+)NCBINCBI36Build 36hg18NCBI36
Build 34399,555,387 - 99,556,353NCBI
Celera396,464,653 - 96,465,618 (+)NCBICelera
Cytogenetic Map3q11.2NCBI
HuRef395,444,762 - 95,445,727 (+)NCBIHuRef
CHM1_1398,035,732 - 98,036,697 (+)NCBICHM1_1
T2T-CHM13v2.03101,057,549 - 101,058,514 (+)NCBIT2T-CHM13v2.0
Or5k16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391658,736,049 - 58,738,849 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1658,734,648 - 58,749,755 (-)EnsemblGRCm39 Ensembl
GRCm381658,915,686 - 58,918,486 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1658,914,285 - 58,929,392 (-)EnsemblGRCm38mm10GRCm38
MGSCv371658,915,512 - 58,918,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361658,857,942 - 58,858,895 (-)NCBIMGSCv36mm8
Celera1659,255,408 - 59,258,208 (-)NCBICelera
Cytogenetic Map16C1.2NCBI
cM Map1634.83NCBI
LOC100974017
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2296,288,295 - 96,289,245 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1396,293,078 - 96,294,028 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0395,447,849 - 95,448,799 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13102,131,411 - 102,132,316 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3102,131,411 - 102,132,316 (+)Ensemblpanpan1.1panPan2
OR5K4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1335,271,605 - 5,272,534 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl335,271,605 - 5,272,534 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha335,450,856 - 5,451,785 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0335,382,347 - 5,383,276 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1335,257,623 - 5,258,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0335,320,459 - 5,321,400 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0335,598,038 - 5,598,967 (+)NCBIUU_Cfam_GSD_1.0
LOC100513883
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13160,992,044 - 160,993,003 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113160,992,044 - 160,993,003 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213172,155,836 - 172,156,772 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103228686
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12282,466,354 - 82,468,071 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604184,094,978 - 84,095,979 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Or5k17
11 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:10
Count of miRNA genes:8
Interacting mature miRNAs:10
Transcripts:ENSRNOT00000048343
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat

Markers in Region
RH127361  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21141,588,176 - 41,588,384 (+)MAPPERmRatBN7.2
mRatBN7.23168,617,919 - 168,618,127 (+)MAPPERmRatBN7.2
Rnor_6.01143,686,489 - 43,686,696NCBIRnor6.0
Rnor_6.03177,009,144 - 177,009,351NCBIRnor6.0
Rnor_5.01146,871,648 - 46,871,855UniSTSRnor5.0
Rnor_5.03180,719,427 - 180,719,634UniSTSRnor5.0
RGSC_v3.43170,651,097 - 170,651,304UniSTSRGSC3.4
RGSC_v3.41142,394,479 - 42,394,686UniSTSRGSC3.4
Celera1141,391,566 - 41,391,773UniSTS
Celera3163,968,841 - 163,969,048UniSTS
RH 3.4 Map31551.9UniSTS
Cytogenetic Map11q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system
High
Medium
Low
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000048343   ⟹   ENSRNOP00000046608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1143,687,107 - 43,688,054 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000060869   ⟹   ENSRNOP00000057592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1141,584,852 - 41,590,142 (+)Ensembl
RefSeq Acc Id: NM_001000725   ⟹   NP_001000725
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81155,057,993 - 55,058,946 (+)NCBI
mRatBN7.21141,588,795 - 41,589,748 (+)NCBI
Rnor_6.01143,687,107 - 43,688,054 (+)NCBI
Rnor_5.01146,872,266 - 46,873,213 (+)NCBI
RGSC_v3.41142,395,097 - 42,396,050 (+)RGD
Celera1141,392,184 - 41,393,137 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000725 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057592
  ENSRNOP00000057592.3
RefSeq Acc Id: NP_001000725   ⟸   NM_001000725
- UniProtKB: D4AC51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000046608   ⟸   ENSRNOT00000048343
RefSeq Acc Id: ENSRNOP00000057592   ⟸   ENSRNOT00000060869
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQK3-F1-model_v2 AlphaFold D3ZQK3 1-315 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333626 AgrOrtholog
BioCyc Gene G2FUF-21582 BioCyc
Ensembl Genes ENSRNOG00000047976 Ensembl
  ENSRNOG00000067747 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060869 ENTREZGENE
  ENSRNOT00000060869.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:404978 UniProtKB/TrEMBL
NCBI Gene 404978 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5k17 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047976 RatGTEx
  ENSRNOG00000067747 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D4AC51 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or5k17  olfactory receptor family 5 subfamily K member 17  Olr1558  olfactory receptor 1558  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1558  olfactory receptor 1558   Olr1558_predicted  olfactory receptor 1558 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1558_predicted  olfactory receptor 1558 (predicted)      Symbol and Name status set to approved 70820 APPROVED