Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of LTN1 mRNA | CTD | PMID:25075043 | (S)-nicotine | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of LTN1 mRNA | CTD | PMID:28065790 | 1,2-dimethylhydrazine | decreases expression | ISO | Ltn1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LTN1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of LTN1 mRNA | CTD | PMID:29097150 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of LTN1 mRNA | CTD | PMID:32145629 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Ltn1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Ltn1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ltn1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LTN1 mRNA | CTD | PMID:19465110 and PMID:21354282 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LTN1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LTN1 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of LTN1 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | LTN1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of LTN1 mRNA | CTD | PMID:21179406 | 2-palmitoylglycerol | increases expression | ISO | LTN1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of LTN1 mRNA | CTD | PMID:37199045 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of LTN1 mRNA | CTD | PMID:30047161 | alpha-phellandrene | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of LTN1 mRNA | CTD | PMID:25075043 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of LTN1 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of LTN1 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to LTN1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | ISO | Ltn1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LTN1 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | Ltn1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of LTN1 exon | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | LTN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LTN1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | Ltn1 (Mus musculus) | 6480464 | Benzo(a)pyrene affects the methylation of LTN1 intron | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of LTN1 mRNA | CTD | PMID:30816183 | bisphenol A | decreases methylation | ISO | LTN1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of LTN1 gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of LTN1 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of LTN1 protein | CTD | PMID:31675489 | bisphenol A | increases expression | ISO | Ltn1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LTN1 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | LTN1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of LTN1 protein | CTD | PMID:32981897 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LTN1 mRNA | CTD | PMID:32145629 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of LTN1 promoter | CTD | PMID:22457795 | cadmium dichloride | affects localization | ISO | LTN1 (Homo sapiens) | 6480464 | Cadmium Chloride affects the localization of LTN1 protein | CTD | PMID:18261755 | calcium silicate | decreases expression | ISO | Ltn1 (Mus musculus) | 6480464 | calcium silicate results in decreased expression of LTN1 mRNA | CTD | PMID:29279043 | celastrol | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | celastrol results in decreased expression of LTN1 mRNA | CTD | PMID:17010675 | CGP 52608 | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LTN1 gene] | CTD | PMID:28238834 | chloroacetaldehyde | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | chloroacetaldehyde results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 | chlorpyrifos | decreases expression | ISO | Ltn1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of LTN1 mRNA | CTD | PMID:37019170 | cidofovir anhydrous | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Cidofovir results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 | cisplatin | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 and PMID:27392435 | cisplatin | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of LTN1 mRNA | CTD | PMID:27392435 | clodronic acid | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Clodronic Acid results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 | cyclosporin A | increases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of LTN1 mRNA | CTD | PMID:25562108 | dicrotophos | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of LTN1 mRNA | CTD | PMID:28302478 | dioxygen | affects expression | ISO | LTN1 (Homo sapiens) | 6480464 | Oxygen deficiency affects the expression of LTN1 mRNA | CTD | PMID:25596134 | dorsomorphin | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LTN1 mRNA | CTD | PMID:27188386 | fenofibrate | decreases expression | EXP | | 6480464 | Fenofibrate results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 | fulvestrant | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of LTN1 gene | CTD | PMID:31601247 | gedunin | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | gedunin results in decreased expression of LTN1 mRNA | CTD | PMID:17010675 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of LTN1 mRNA | CTD | PMID:22061828 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of LTN1 mRNA | CTD | PMID:24136188 | glycerol | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of LTN1 mRNA | CTD | PMID:28065790 | ifosfamide | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Ifosfamide results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of LTN1 mRNA | CTD | PMID:25596134 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of LTN1 mRNA | CTD | PMID:30467583 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of LTN1 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of LTN1 mRNA | CTD | PMID:23649840 | myricetin | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | myricetin results in decreased expression of LTN1 protein | CTD | PMID:29698783 | nicotine | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of LTN1 mRNA | CTD | PMID:28065790 | paracetamol | affects expression | ISO | Ltn1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LTN1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of LTN1 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LTN1 mRNA | CTD | PMID:21420995 | PCB138 | multiple interactions | ISO | Ltn1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of LTN1 mRNA | CTD | PMID:27153767 | phenobarbital | affects expression | ISO | Ltn1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of LTN1 mRNA | CTD | PMID:23091169 | pirinixic acid | decreases expression | ISO | Ltn1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LTN1 mRNA | CTD | PMID:18445702 | propane-1,2-diol | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of LTN1 mRNA | CTD | PMID:28065790 | resveratrol | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of LTN1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LTN1 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | Ltn1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of LTN1 mRNA | CTD | PMID:36209798 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of LTN1 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of LTN1 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of LTN1 mRNA | CTD | PMID:31758290 | thapsigargin | increases expression | ISO | Ltn1 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of LTN1 protein | CTD | PMID:24648495 | thimerosal | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of LTN1 mRNA | CTD | PMID:27188386 | trichostatin A | multiple interactions | ISO | LTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LTN1 mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of LTN1 mRNA | CTD | PMID:24935251 and PMID:26272509 | tunicamycin | increases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of LTN1 mRNA | CTD | PMID:22378314 | valproic acid | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of LTN1 mRNA | CTD | PMID:23179753 and PMID:27188386 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of LTN1 mRNA | CTD | PMID:23034163 | vorinostat | decreases expression | ISO | LTN1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of LTN1 mRNA | CTD | PMID:27188386 | |