Kcnj15 (potassium inwardly-rectifying channel, subfamily J, member 15) - Rat Genome Database

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Gene: Kcnj15 (potassium inwardly-rectifying channel, subfamily J, member 15) Rattus norvegicus
Analyze
Symbol: Kcnj15
Name: potassium inwardly-rectifying channel, subfamily J, member 15
RGD ID: 621662
Description: Enables inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to act upstream of or within potassium ion transmembrane transport. Located in plasma membrane. Orthologous to human KCNJ15 (potassium inwardly rectifying channel subfamily J member 15); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-sensitive inward rectifier potassium channel 15; inward rectifier K(+) channel Kir4.2; Kir4.2; potassium channel, inwardly rectifying subfamily J member 15; potassium channel, inwardly rectifying subfamily J, member 15; potassium voltage-gated channel subfamily J member 15
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Kcnj15_v1   Kcnj15_v2  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,577,397 - 34,621,725 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1134,577,363 - 34,621,952 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,259,050 - 43,276,248 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01135,930,427 - 35,947,631 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01135,075,871 - 35,093,073 (+)NCBIRnor_WKY
Rnor_6.01135,545,185 - 35,588,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,568,182 - 35,585,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,131,386 - 39,174,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,577,083 - 35,594,291 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,633,325 - 35,650,534NCBI
Celera1133,838,675 - 33,855,881 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Estradiol attenuates hypoxia-induced pulmonary endothelin-1 gene expression. Earley S and Resta TC, Am J Physiol Lung Cell Mol Physiol 2002 Jul;283(1):L86-93.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Cloning, expression, and localization of a rat hepatocyte inwardly rectifying potassium channel. Hill CE, etal., Am J Physiol Gastrointest Liver Physiol 2002 Feb;282(2):G233-40.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9882736   PMID:22566534  


Genomics

Comparative Map Data
Kcnj15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,577,397 - 34,621,725 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1134,577,363 - 34,621,952 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,259,050 - 43,276,248 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01135,930,427 - 35,947,631 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01135,075,871 - 35,093,073 (+)NCBIRnor_WKY
Rnor_6.01135,545,185 - 35,588,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,568,182 - 35,585,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,131,386 - 39,174,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,577,083 - 35,594,291 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,633,325 - 35,650,534NCBI
Celera1133,838,675 - 33,855,881 (-)NCBICelera
Cytogenetic Map11q11NCBI
KCNJ15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382138,229,926 - 38,307,357 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2138,155,549 - 38,307,357 (+)EnsemblGRCh38hg38GRCh38
GRCh372139,601,848 - 39,679,279 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362138,550,534 - 38,595,618 (+)NCBINCBI36Build 36hg18NCBI36
Build 342138,566,298 - 38,595,614NCBI
Celera2124,826,521 - 24,871,607 (+)NCBICelera
Cytogenetic Map21q22.13-q22.2NCBI
HuRef2125,071,310 - 25,143,209 (+)NCBIHuRef
CHM1_12139,162,401 - 39,234,297 (+)NCBICHM1_1
T2T-CHM13v2.02136,613,403 - 36,690,781 (+)NCBIT2T-CHM13v2.0
Kcnj15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,058,417 - 95,101,119 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1695,058,417 - 95,101,119 (+)EnsemblGRCm39 Ensembl
GRCm381695,257,558 - 95,300,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,257,558 - 95,300,260 (+)EnsemblGRCm38mm10GRCm38
MGSCv371695,479,258 - 95,521,867 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361695,366,449 - 95,409,058 (+)NCBIMGSCv36mm8
Celera1696,370,059 - 96,378,516 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1655.86NCBI
Kcnj15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540737,267,926 - 37,313,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540737,261,892 - 37,313,484 (+)NCBIChiLan1.0ChiLan1.0
KCNJ15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12137,965,966 - 38,018,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,010,261 - 38,011,388 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02124,615,779 - 24,668,267 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
KCNJ15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13133,314,061 - 33,388,165 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3133,384,630 - 33,386,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3132,384,569 - 32,464,144 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03132,625,207 - 32,704,035 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3132,696,131 - 32,697,261 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13132,500,044 - 32,579,477 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03132,504,526 - 32,583,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03132,992,265 - 33,071,945 (+)NCBIUU_Cfam_GSD_1.0
Kcnj15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497132,738,310 - 32,782,796 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365004,684,954 - 4,728,111 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365004,685,832 - 4,690,338 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13201,894,420 - 201,939,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113201,894,036 - 201,941,449 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213211,979,376 - 212,024,780 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNJ15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,207,680 - 82,266,863 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl282,254,088 - 82,255,215 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605410,061,726 - 10,109,851 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474525,517,157 - 25,560,668 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474525,515,159 - 25,560,677 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnj15
151 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:88
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000002259
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat

Markers in Region
Kcnj15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21134,618,012 - 34,618,257 (+)MAPPERmRatBN7.2
Rnor_6.01135,584,805 - 35,585,049NCBIRnor6.0
Rnor_5.01139,171,127 - 39,171,371UniSTSRnor5.0
RGSC_v3.41135,593,706 - 35,593,950UniSTSRGSC3.4
Celera1133,839,016 - 33,839,260UniSTS
Cytogenetic Map11q11UniSTS
AU048908  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21134,612,736 - 34,612,984 (+)MAPPERmRatBN7.2
Rnor_6.01135,579,529 - 35,579,776NCBIRnor6.0
Rnor_5.01139,165,851 - 39,166,098UniSTSRnor5.0
RGSC_v3.41135,588,430 - 35,588,677UniSTSRGSC3.4
Celera1133,844,289 - 33,844,536UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 33 11
Low 3 23 31 15 19 15 28 2 36
Below cutoff 17 24 24 24 7 9 44 5 7

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY028455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000002259   ⟹   ENSRNOP00000002259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,601,076 - 34,621,150 (+)Ensembl
Rnor_6.0 Ensembl1135,568,182 - 35,585,390 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094937   ⟹   ENSRNOP00000092361
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,601,076 - 34,621,952 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099760   ⟹   ENSRNOP00000091174
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,577,364 - 34,621,874 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104151   ⟹   ENSRNOP00000089124
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,605,054 - 34,621,952 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108557   ⟹   ENSRNOP00000078466
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,577,363 - 34,621,952 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111269   ⟹   ENSRNOP00000087933
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,577,441 - 34,621,758 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111664   ⟹   ENSRNOP00000093558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,577,363 - 34,621,952 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113883   ⟹   ENSRNOP00000097650
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,577,402 - 34,621,874 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118577   ⟹   ENSRNOP00000077685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,602,675 - 34,621,952 (+)Ensembl
RefSeq Acc Id: NM_133321   ⟹   NP_579855
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,601,390 - 34,618,598 (+)NCBI
Rnor_6.01135,568,182 - 35,585,390 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
RGSC_v3.41135,577,083 - 35,594,291 (+)RGD
Celera1133,838,675 - 33,855,881 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248128   ⟹   XP_006248190
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,397 - 34,621,725 (+)NCBI
Rnor_6.01135,545,375 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248129   ⟹   XP_006248191
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,415 - 34,621,725 (+)NCBI
Rnor_6.01135,545,185 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248131   ⟹   XP_006248193
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,397 - 34,621,725 (+)NCBI
Rnor_6.01135,545,185 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248132   ⟹   XP_006248194
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,495 - 34,621,725 (+)NCBI
Rnor_6.01135,545,185 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248133   ⟹   XP_006248195
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,649 - 34,621,725 (+)NCBI
Rnor_6.01135,545,760 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248135   ⟹   XP_006248197
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,612,092 - 34,621,725 (+)NCBI
Rnor_6.01135,579,643 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248139   ⟹   XP_006248201
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,416 - 34,621,725 (+)NCBI
Rnor_6.01135,545,187 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248141   ⟹   XP_006248203
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,614,728 - 34,621,725 (+)NCBI
Rnor_6.01135,580,389 - 35,588,517 (+)NCBI
Rnor_5.01139,131,386 - 39,174,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768550   ⟹   XP_008766772
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,399 - 34,621,725 (+)NCBI
Rnor_6.01135,545,185 - 35,588,517 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768552   ⟹   XP_008766774
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,649 - 34,621,725 (+)NCBI
Rnor_6.01135,545,771 - 35,588,517 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597862   ⟹   XP_017453351
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,649 - 34,621,725 (+)NCBI
Rnor_6.01135,545,549 - 35,588,517 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039087923   ⟹   XP_038943851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,404 - 34,621,725 (+)NCBI
RefSeq Acc Id: XM_039087924   ⟹   XP_038943852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,612,094 - 34,621,725 (+)NCBI
RefSeq Acc Id: XM_039087925   ⟹   XP_038943853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,950 - 34,621,725 (+)NCBI
RefSeq Acc Id: XM_039087926   ⟹   XP_038943854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,650 - 34,621,725 (+)NCBI
RefSeq Acc Id: XM_039087927   ⟹   XP_038943855
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,577,399 - 34,621,725 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_579855   ⟸   NM_133321
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248193   ⟸   XM_006248131
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248201   ⟸   XM_006248139
- Peptide Label: isoform X3
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248191   ⟸   XM_006248129
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248194   ⟸   XM_006248132
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248190   ⟸   XM_006248128
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248195   ⟸   XM_006248133
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248197   ⟸   XM_006248135
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248203   ⟸   XM_006248141
- Peptide Label: isoform X3
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766772   ⟸   XM_008768550
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766774   ⟸   XM_008768552
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017453351   ⟸   XM_017597862
- Peptide Label: isoform X2
- UniProtKB: Q91ZF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002259   ⟸   ENSRNOT00000002259
RefSeq Acc Id: XP_038943855   ⟸   XM_039087927
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038943851   ⟸   XM_039087923
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038943854   ⟸   XM_039087926
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038943853   ⟸   XM_039087925
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038943852   ⟸   XM_039087924
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000097650   ⟸   ENSRNOT00000113883
RefSeq Acc Id: ENSRNOP00000091174   ⟸   ENSRNOT00000099760
RefSeq Acc Id: ENSRNOP00000089124   ⟸   ENSRNOT00000104151
RefSeq Acc Id: ENSRNOP00000093558   ⟸   ENSRNOT00000111664
RefSeq Acc Id: ENSRNOP00000087933   ⟸   ENSRNOT00000111269
RefSeq Acc Id: ENSRNOP00000092361   ⟸   ENSRNOT00000094937
RefSeq Acc Id: ENSRNOP00000078466   ⟸   ENSRNOT00000108557
RefSeq Acc Id: ENSRNOP00000077685   ⟸   ENSRNOT00000118577
Protein Domains
Inward rectifier potassium channel C-terminal   Potassium channel inwardly rectifying transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91ZF1-F1-model_v2 AlphaFold Q91ZF1 1-405 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698081
Promoter ID:EPDNEW_R8606
Type:single initiation site
Name:Kcnj15_1
Description:potassium voltage-gated channel subfamily J member 15
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01135,568,182 - 35,568,242EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621662 AgrOrtholog
BioCyc Gene G2FUF-21728 BioCyc
Ensembl Genes ENSRNOG00000001656 Ensembl
  ENSRNOG00000062944 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002259.2 UniProtKB/TrEMBL
  ENSRNOP00000077685 ENTREZGENE
  ENSRNOP00000077685.1 UniProtKB/Swiss-Prot
  ENSRNOP00000078466 ENTREZGENE
  ENSRNOP00000078466.1 UniProtKB/Swiss-Prot
  ENSRNOP00000087933.1 UniProtKB/Swiss-Prot
  ENSRNOP00000089124.1 UniProtKB/Swiss-Prot
  ENSRNOP00000091174.1 UniProtKB/Swiss-Prot
  ENSRNOP00000092361.1 UniProtKB/Swiss-Prot
  ENSRNOP00000093558 ENTREZGENE
  ENSRNOP00000093558.1 UniProtKB/Swiss-Prot
  ENSRNOP00000097650 ENTREZGENE
  ENSRNOP00000097650.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002259.3 UniProtKB/TrEMBL
  ENSRNOT00000094937.1 UniProtKB/Swiss-Prot
  ENSRNOT00000099760.1 UniProtKB/Swiss-Prot
  ENSRNOT00000104151.1 UniProtKB/Swiss-Prot
  ENSRNOT00000108557 ENTREZGENE
  ENSRNOT00000108557.1 UniProtKB/Swiss-Prot
  ENSRNOT00000111269.1 UniProtKB/Swiss-Prot
  ENSRNOT00000111664 ENTREZGENE
  ENSRNOT00000111664.1 UniProtKB/Swiss-Prot
  ENSRNOT00000113883 ENTREZGENE
  ENSRNOT00000113883.1 UniProtKB/Swiss-Prot
  ENSRNOT00000118577 ENTREZGENE
  ENSRNOT00000118577.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir1.3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kir_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:170847 UniProtKB/Swiss-Prot
NCBI Gene 170847 ENTREZGENE
PANTHER PTHR11767 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11767:SF20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kcnj15 PhenoGen
PIRSF GIRK_kir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS KIR13CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2PZJ4_RAT UniProtKB/TrEMBL
  KCJ15_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-19 Kcnj15  potassium inwardly-rectifying channel, subfamily J, member 15  Kcnj15  potassium voltage-gated channel subfamily J member 15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Kcnj15  potassium voltage-gated channel subfamily J member 15  Kcnj15  potassium channel, inwardly rectifying subfamily J, member 15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-26 Kcnj15  potassium channel, inwardly rectifying subfamily J, member 15  Kcnj15  potassium inwardly-rectifying channel, subfamily J, member 15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Kcnj15  potassium inwardly-rectifying channel, subfamily J, member 15      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Kcnj15  potassium inwardly-rectifying channel, subfamily J, member 15      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the basolateral membrane 625743
gene_cellular_localization contians two isoforms, Kcnj15_v1 (Kir4.2) and Kcnj15_v2 (Kir4.2a)  
gene_process may play a role in maintaining electrical integrity of bile-generating hepatocytes 625753
gene_transcript transcript consists of two isoforms 625743
gene_transcript contians two isoforms, Kcnj15_v1 (Kir4.2) and Kcnj15_v2 (Kir4.2a) 625753