KCNJ15 (potassium inwardly rectifying channel subfamily J member 15) - Rat Genome Database

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Gene: KCNJ15 (potassium inwardly rectifying channel subfamily J member 15) Pan paniscus
Analyze
Symbol: KCNJ15
Name: potassium inwardly rectifying channel subfamily J member 15
RGD ID: 11841000
Description: ENCODES a protein that exhibits inward rectifier potassium channel activity (ortholog); potassium channel activity (ortholog); INVOLVED IN potassium ion transmembrane transport (ortholog); potassium ion transport (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN membrane (inferred); monoatomic ion channel complex (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-sensitive inward rectifier potassium channel 15; Down syndrome critical region protein 8; LOC103782695; potassium inwardly-rectifying channel, subfamily J, member 15; potassium voltage-gated channel subfamily J member 15; uncharacterized LOC103782695
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22234,273,400 - 34,419,251 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12129,131,812 - 29,278,181 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02124,615,779 - 24,668,267 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12137,965,966 - 38,018,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,010,261 - 38,011,388 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNJ15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22234,273,400 - 34,419,251 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12129,131,812 - 29,278,181 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02124,615,779 - 24,668,267 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12137,965,966 - 38,018,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,010,261 - 38,011,388 (+)Ensemblpanpan1.1panPan2
KCNJ15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382138,229,926 - 38,307,357 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2138,155,549 - 38,307,357 (+)EnsemblGRCh38hg38GRCh38
GRCh372139,601,848 - 39,679,279 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362138,550,534 - 38,595,618 (+)NCBINCBI36Build 36hg18NCBI36
Build 342138,566,298 - 38,595,614NCBI
Celera2124,826,521 - 24,871,607 (+)NCBICelera
Cytogenetic Map21q22.13-q22.2NCBI
HuRef2125,071,310 - 25,143,209 (+)NCBIHuRef
CHM1_12139,162,401 - 39,234,297 (+)NCBICHM1_1
T2T-CHM13v2.02136,613,403 - 36,690,781 (+)NCBIT2T-CHM13v2.0
Kcnj15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,058,417 - 95,101,119 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1695,058,417 - 95,101,119 (+)EnsemblGRCm39 Ensembl
GRCm381695,257,558 - 95,300,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,257,558 - 95,300,260 (+)EnsemblGRCm38mm10GRCm38
MGSCv371695,479,258 - 95,521,867 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361695,366,449 - 95,409,058 (+)NCBIMGSCv36mm8
Celera1696,370,059 - 96,378,516 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1655.86NCBI
Kcnj15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,046,953 - 48,091,285 (+)NCBIGRCr8
mRatBN7.21134,577,397 - 34,621,725 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1134,577,363 - 34,621,952 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,259,050 - 43,276,248 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,930,427 - 35,947,631 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,075,871 - 35,093,073 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01135,545,185 - 35,588,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,568,182 - 35,585,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,131,386 - 39,174,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,577,083 - 35,594,291 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,633,325 - 35,650,534NCBI
Celera1133,838,675 - 33,855,881 (-)NCBICelera
Cytogenetic Map11q11NCBI
Kcnj15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540737,267,926 - 37,313,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540737,261,892 - 37,313,484 (+)NCBIChiLan1.0ChiLan1.0
KCNJ15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13133,314,061 - 33,388,165 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3133,384,630 - 33,386,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3132,384,569 - 32,464,144 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03132,625,207 - 32,704,035 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3132,696,131 - 32,697,261 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13132,500,044 - 32,579,477 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03132,504,526 - 32,583,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03132,992,265 - 33,071,945 (+)NCBIUU_Cfam_GSD_1.0
Kcnj15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497132,738,310 - 32,782,796 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365004,684,954 - 4,728,111 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365004,685,832 - 4,690,338 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13201,894,420 - 201,939,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113201,894,036 - 201,941,449 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213211,979,376 - 212,024,780 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNJ15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,207,680 - 82,266,863 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl282,254,088 - 82,255,215 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605410,061,726 - 10,109,851 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474525,517,157 - 25,560,668 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474525,515,159 - 25,560,677 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000040643   ⟹   ENSPPAP00000017922
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2138,010,261 - 38,011,388 (+)Ensembl
RefSeq Acc Id: XM_003823934   ⟹   XP_003823982
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,409,384 - 34,419,251 (+)NCBI
NHGRI_mPanPan12129,268,907 - 29,273,117 (+)NCBI
Mhudiblu_PPA_v02124,629,516 - 24,662,729 (+)NCBI
PanPan1.12137,979,652 - 38,014,694 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055105195   ⟹   XP_054961170
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,273,424 - 34,419,251 (+)NCBI
NHGRI_mPanPan12129,131,812 - 29,278,181 (+)NCBI
RefSeq Acc Id: XM_063601391   ⟹   XP_063457461
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,273,400 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601392   ⟹   XP_063457462
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,273,430 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601393   ⟹   XP_063457463
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,408,019 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601394   ⟹   XP_063457464
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,408,455 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601395   ⟹   XP_063457465
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,273,430 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601396   ⟹   XP_063457466
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,273,411 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601397   ⟹   XP_063457467
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,273,439 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601398   ⟹   XP_063457468
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,408,019 - 34,419,251 (+)NCBI
RefSeq Acc Id: XM_063601399   ⟹   XP_063457469
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22234,285,937 - 34,419,251 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003823982   ⟸   XM_003823934
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000017922   ⟸   ENSPPAT00000040643
RefSeq Acc Id: XP_054961170   ⟸   XM_055105195
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AKM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063457461   ⟸   XM_063601391
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457466   ⟸   XM_063601396
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457465   ⟸   XM_063601395
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457462   ⟸   XM_063601392
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457467   ⟸   XM_063601397
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457469   ⟸   XM_063601399
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457468   ⟸   XM_063601398
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457463   ⟸   XM_063601393
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457464   ⟸   XM_063601394
- Peptide Label: isoform X2
Protein Domains
Inward rectifier potassium channel C-terminal   Potassium channel inwardly rectifying transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032085 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAG00000037211 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040643.1 UniProtKB/TrEMBL
  ENSPPAT00000051189.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir1.3 UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/TrEMBL
  Kir_TM UniProtKB/TrEMBL
KEGG Report pps:100971942 UniProtKB/TrEMBL
NCBI Gene KCNJ15 ENTREZGENE
PANTHER PTHR11767 UniProtKB/TrEMBL
  PTHR11767:SF20 UniProtKB/TrEMBL
Pfam IRK UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
PIRSF GIRK_kir UniProtKB/TrEMBL
PRINTS KIR13CHANNEL UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A2R9AKM3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BGE8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 KCNJ15  potassium inwardly rectifying channel subfamily J member 15  LOC103782695  Down syndrome critical region protein 8  Data merged from RGD:11895539 737654 PROVISIONAL
2019-07-23 KCNJ15  potassium inwardly rectifying channel subfamily J member 15  KCNJ15  potassium voltage-gated channel subfamily J member 15  Symbol and/or name change 5135510 APPROVED
2018-05-08 LOC103782695  Down syndrome critical region protein 8    uncharacterized LOC103782695  Symbol and/or name change 5135510 APPROVED