Rnf168 (ring finger protein 168) - Rat Genome Database

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Gene: Rnf168 (ring finger protein 168) Rattus norvegicus
Analyze
Symbol: Rnf168
Name: ring finger protein 168
RGD ID: 1585168
Description: Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; histone H2AK15 ubiquitin ligase activity; and ubiquitin binding activity. Predicted to be involved in several processes, including DNA metabolic process; chromatin remodeling; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within cellular response to UV and regulation of protein localization. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of DNA repair complex and ubiquitin ligase complex. Predicted to be active in nucleus and site of double-strand break. Human ortholog(s) of this gene implicated in RIDDLE syndrome. Orthologous to human RNF168 (ring finger protein 168); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase RNF168; LOC690043; MGC188789; ring finger protein 168, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF168; similar to ring finger protein 168
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21168,486,313 - 68,508,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,486,321 - 68,508,277 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1177,323,357 - 77,345,315 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,987,965 - 70,010,092 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,012,484 - 69,034,433 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,721,242 - 71,743,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,721,250 - 71,743,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,805,354 - 74,827,533 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,304,917 - 70,328,010 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1167,918,463 - 67,940,284 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
DNA repair complex  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO,ISS)
protein-containing complex  (ISO)
site of double-strand break  (IBA,IEA,ISO,ISS)
ubiquitin ligase complex  (IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ATM protein kinase: the linchpin of cellular defenses to stress. Bhatti S, etal., Cell Mol Life Sci. 2011 Sep;68(18):2977-3006. doi: 10.1007/s00018-011-0683-9. Epub 2011 May 2.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Double-strand break repair: 53BP1 comes into focus. Panier S and Boulton SJ, Nat Rev Mol Cell Biol. 2014 Jan;15(1):7-18. doi: 10.1038/nrm3719. Epub 2013 Dec 11.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:19203578   PMID:19203579   PMID:19500350   PMID:20080757   PMID:20550933   PMID:21041483   PMID:22266820   PMID:22373579   PMID:22508508   PMID:22742833   PMID:22980979  
PMID:23760478   PMID:24217620  


Genomics

Comparative Map Data
Rnf168
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21168,486,313 - 68,508,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,486,321 - 68,508,277 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1177,323,357 - 77,345,315 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,987,965 - 70,010,092 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,012,484 - 69,034,433 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,721,242 - 71,743,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,721,250 - 71,743,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,805,354 - 74,827,533 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,304,917 - 70,328,010 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1167,918,463 - 67,940,284 (-)NCBICelera
Cytogenetic Map11q22NCBI
RNF168
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383196,468,783 - 196,503,768 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3196,468,783 - 196,503,768 (-)EnsemblGRCh38hg38GRCh38
GRCh373196,195,654 - 196,230,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,683,025 - 197,714,979 (-)NCBINCBI36Build 36hg18NCBI36
Build 343197,686,938 - 197,718,892NCBI
Celera3194,777,591 - 194,812,751 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3193,493,420 - 193,527,598 (-)NCBIHuRef
CHM1_13196,167,064 - 196,202,063 (-)NCBICHM1_1
T2T-CHM13v2.03199,187,976 - 199,222,947 (-)NCBIT2T-CHM13v2.0
Rnf168
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,096,279 - 32,120,260 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,096,277 - 32,120,252 (+)EnsemblGRCm39 Ensembl
GRCm381632,277,461 - 32,301,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,277,459 - 32,301,434 (+)EnsemblGRCm38mm10GRCm38
MGSCv371632,277,547 - 32,301,528 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361632,197,236 - 32,220,653 (+)NCBIMGSCv36mm8
Celera1632,762,446 - 32,786,422 (+)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1622.51NCBI
Rnf168
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,657,272 - 12,676,426 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542012,656,815 - 12,676,836 (-)NCBIChiLan1.0ChiLan1.0
RNF168
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan13194,341,443 - 194,379,313 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,814,785 - 193,848,620 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,755,988 - 203,791,324 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,756,589 - 203,790,687 (-)Ensemblpanpan1.1panPan2
RNF168
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13329,542,209 - 29,575,127 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3329,539,182 - 29,628,248 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3329,566,807 - 29,599,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03329,784,005 - 29,817,553 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3329,783,909 - 29,817,527 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13329,563,108 - 29,596,234 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03329,618,089 - 29,651,643 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03330,240,484 - 30,273,553 (-)NCBIUU_Cfam_GSD_1.0
Rnf168
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602124,790,716 - 124,813,795 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367841,073,236 - 1,094,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF168
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113133,625,534 - 133,659,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNF168
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11590,702,740 - 90,735,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1590,702,765 - 90,737,687 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604164,501,700 - 64,536,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf168
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,591,943 - 61,627,170 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473061,592,967 - 61,627,585 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf168
201 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:311
Count of miRNA genes:190
Interacting mature miRNAs:232
Transcripts:ENSRNOT00000002395
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat

Markers in Region
RH139965  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,487,369 - 68,487,579 (+)MAPPERmRatBN7.2
Rnor_6.01171,722,299 - 71,722,508NCBIRnor6.0
Rnor_5.01174,806,411 - 74,806,620UniSTSRnor5.0
RGSC_v3.41170,305,421 - 70,305,630UniSTSRGSC3.4
Celera1167,919,520 - 67,919,729UniSTS
RH 3.4 Map11392.9UniSTS
Cytogenetic Map11q22UniSTS
RH136967  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,486,899 - 68,487,084 (+)MAPPERmRatBN7.2
Rnor_6.01171,721,829 - 71,722,013NCBIRnor6.0
Rnor_5.01174,805,941 - 74,806,125UniSTSRnor5.0
RGSC_v3.41170,304,951 - 70,305,135UniSTSRGSC3.4
Celera1167,919,050 - 67,919,234UniSTS
RH 3.4 Map11403.0UniSTS
Cytogenetic Map11q22UniSTS
AU048786  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,490,453 - 68,490,702 (+)MAPPERmRatBN7.2
Rnor_6.01171,725,608 - 71,725,856NCBIRnor6.0
Rnor_5.01174,809,720 - 74,809,968UniSTSRnor5.0
RGSC_v3.41170,308,505 - 70,308,753UniSTSRGSC3.4
Cytogenetic Map11q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 32 18 19 18 74 22 41 11
Low 17 25 23 23 8 11 13 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000002395   ⟹   ENSRNOP00000002395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,486,321 - 68,508,277 (-)Ensembl
Rnor_6.0 Ensembl1171,721,250 - 71,743,421 (-)Ensembl
RefSeq Acc Id: NM_001127597   ⟹   NP_001121069
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,486,313 - 68,508,277 (-)NCBI
Rnor_6.01171,721,242 - 71,743,421 (-)NCBI
Rnor_5.01174,805,354 - 74,827,533 (-)NCBI
RGSC_v3.41170,304,917 - 70,328,010 (-)RGD
Celera1167,918,463 - 67,940,284 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088630   ⟹   XP_038944558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,486,313 - 68,500,964 (-)NCBI
RefSeq Acc Id: XM_039088631   ⟹   XP_038944559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,488,393 - 68,508,296 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001121069 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944558 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944559 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66869 (Get FASTA)   NCBI Sequence Viewer  
  B2RYR0 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002395
  ENSRNOP00000002395.7
RefSeq Acc Id: NP_001121069   ⟸   NM_001127597
- UniProtKB: B2RYR0 (UniProtKB/Swiss-Prot),   A0A140TA93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002395   ⟸   ENSRNOT00000002395
RefSeq Acc Id: XP_038944558   ⟸   XM_039088630
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944559   ⟸   XM_039088631
- Peptide Label: isoform X2
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYR0-F1-model_v2 AlphaFold B2RYR0 1-564 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1585168 AgrOrtholog
BioCyc Gene G2FUF-21090 BioCyc
Ensembl Genes ENSRNOG00000043345 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002395 ENTREZGENE
  ENSRNOT00000002395.8 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9030307 IMAGE-MGC_LOAD
InterPro RNF168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:690043 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:188789 IMAGE-MGC_LOAD
NCBI Gene 690043 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-C3HC4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf168 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000043345 RatGTEx
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140TA93 ENTREZGENE, UniProtKB/TrEMBL
  B2RYR0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Rnf168  ring finger protein 168  Rnf168  ring finger protein 168, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-15 Rnf168  ring finger protein 168, E3 ubiquitin protein ligase  Rnf168  ring finger protein 168  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-22 Rnf168  ring finger protein 168  LOC690043  similar to ring finger protein 168  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC690043  similar to ring finger protein 168      Symbol and Name status set to provisional 70820 PROVISIONAL