Umps (uridine monophosphate synthetase) - Rat Genome Database

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Gene: Umps (uridine monophosphate synthetase) Rattus norvegicus
Analyze
Symbol: Umps
Name: uridine monophosphate synthetase
RGD ID: 1311908
Description: Enables orotate phosphoribosyltransferase activity and orotidine-5'-phosphate decarboxylase activity. Involved in several processes, including UMP biosynthetic process; female pregnancy; and lactation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Orthologous to human UMPS (uridine monophosphate synthetase); PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC288051; uridine 5'-monophosphate synthase; uridine monophosphate synthase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21166,806,107 - 66,816,520 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,806,045 - 66,821,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,639,569 - 75,649,990 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01168,301,455 - 68,311,876 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01167,332,029 - 67,342,450 (+)NCBIRnor_WKY
Rnor_6.01170,034,181 - 70,044,590 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,034,139 - 70,044,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,123,827 - 73,134,236 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,619,835 - 68,630,244 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,677,423 - 68,687,833 (+)NCBI
Celera1166,256,748 - 66,267,157 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-gambogic acid  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
5-fluorouracil  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
azaribine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
ivermectin  (ISO)
methotrexate  (ISO)
mitomycin C  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel dichloride  (ISO)
nimesulide  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP)
perfluorooctanoic acid  (ISO)
pioglitazone  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
wogonin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway. Evans DR and Guy HI, J Biol Chem. 2004 Aug 6;279(32):33035-8. Epub 2004 Apr 19.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Pyrimidine nucleotide synthesis in the rat mammary gland: changes in the lactation cycle and effects of diabetes. Kunjara S, etal., Biochem Med Metab Biol. 1992 Dec;48(3):263-74.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Identification of new SNPs associated with severe toxicity to capecitabine. Pellicer M, etal., Pharmacol Res. 2017 Jun;120:133-137. doi: 10.1016/j.phrs.2017.03.021. Epub 2017 Mar 27.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families. Suchi M, etal., Am J Hum Genet. 1997 Mar;60(3):525-39.
14. Increased levels of UMP synthase protein and mRNA in pyrazofurin-resistant rat hepatoma cells. Suttle DP J Biol Chem. 1983 Jun 25;258(12):7707-13.
15. Regulation of purine and pyrimidine metabolism by insulin and by resistance to tiazofurin. Weber G, etal., Adv Enzyme Regul. 1985;23:81-99.
Additional References at PubMed
PMID:6893554   PMID:11730338   PMID:12477932   PMID:15890648   PMID:18184586  


Genomics

Comparative Map Data
Umps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21166,806,107 - 66,816,520 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,806,045 - 66,821,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,639,569 - 75,649,990 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01168,301,455 - 68,311,876 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01167,332,029 - 67,342,450 (+)NCBIRnor_WKY
Rnor_6.01170,034,181 - 70,044,590 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,034,139 - 70,044,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,123,827 - 73,134,236 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,619,835 - 68,630,244 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,677,423 - 68,687,833 (+)NCBI
Celera1166,256,748 - 66,267,157 (+)NCBICelera
Cytogenetic Map11q22NCBI
UMPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383124,730,452 - 124,749,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3124,730,433 - 124,749,273 (+)EnsemblGRCh38hg38GRCh38
GRCh373124,449,299 - 124,468,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,931,903 - 125,946,318 (+)NCBINCBI36Build 36hg18NCBI36
Build 343125,931,902 - 125,946,318NCBI
Celera3122,856,384 - 122,875,279 (+)NCBICelera
Cytogenetic Map3q21.2NCBI
HuRef3121,823,485 - 121,842,386 (+)NCBIHuRef
CHM1_13124,412,201 - 124,431,088 (+)NCBICHM1_1
T2T-CHM13v2.03127,456,263 - 127,475,096 (+)NCBIT2T-CHM13v2.0
Umps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,775,152 - 33,787,408 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1633,775,152 - 33,787,408 (-)EnsemblGRCm39 Ensembl
GRCm381633,954,782 - 33,967,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,954,782 - 33,967,038 (-)EnsemblGRCm38mm10GRCm38
MGSCv371633,955,098 - 33,967,089 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361633,874,759 - 33,886,750 (-)NCBIMGSCv36mm8
Celera1634,439,142 - 34,451,132 (-)NCBICelera
Cytogenetic Map16B3NCBI
Umps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542723,825,523 - 23,841,152 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542723,825,529 - 23,841,427 (+)NCBIChiLan1.0ChiLan1.0
UMPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13128,731,309 - 128,745,241 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3128,731,355 - 128,745,029 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03121,832,758 - 121,851,707 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
UMPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13327,754,592 - 27,782,517 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3327,754,643 - 27,782,514 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3327,778,349 - 27,806,263 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03327,991,347 - 28,019,249 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3327,991,386 - 28,019,245 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13327,786,637 - 27,814,528 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03327,830,936 - 27,858,855 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03328,449,678 - 28,477,605 (+)NCBIUU_Cfam_GSD_1.0
Umps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602126,644,830 - 126,656,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936725549,804 - 565,141 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936725553,278 - 564,846 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UMPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13135,610,058 - 135,650,603 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113135,611,857 - 135,650,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,113,405 - 145,154,901 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UMPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12256,081,897 - 56,097,164 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2256,082,103 - 56,097,105 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041110,226,585 - 110,241,588 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Umps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624731761,210 - 779,321 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624731761,235 - 780,355 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Umps
76 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:75
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000002450
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat

Markers in Region
AI044813  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,811,046 - 66,811,249 (+)MAPPERmRatBN7.2
Rnor_6.01170,039,119 - 70,039,321NCBIRnor6.0
Rnor_5.01173,128,765 - 73,128,967UniSTSRnor5.0
RGSC_v3.41168,624,773 - 68,624,975UniSTSRGSC3.4
Celera1166,261,686 - 66,261,888UniSTS
RH 3.4 Map11421.5UniSTS
Cytogenetic Map11q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 5 7 74 35 41 11 5
Low 6 3 4 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002450   ⟹   ENSRNOP00000002450
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,806,045 - 66,821,903 (+)Ensembl
Rnor_6.0 Ensembl1170,034,139 - 70,044,628 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117390   ⟹   ENSRNOP00000085385
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,806,096 - 66,818,056 (+)Ensembl
RefSeq Acc Id: NM_001025402   ⟹   NP_001020573
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21166,806,109 - 66,816,518 (+)NCBI
Rnor_6.01170,034,181 - 70,044,590 (+)NCBI
Rnor_5.01173,123,827 - 73,134,236 (+)NCBI
RGSC_v3.41168,619,835 - 68,630,244 (+)RGD
Celera1166,256,748 - 66,267,157 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088118   ⟹   XP_038944046
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21166,806,107 - 66,816,520 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001020573 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944046 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98033 (Get FASTA)   NCBI Sequence Viewer  
  EDM11351 (Get FASTA)   NCBI Sequence Viewer  
  EDM11352 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001020573   ⟸   NM_001025402
- UniProtKB: Q4QQS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002450   ⟸   ENSRNOT00000002450
RefSeq Acc Id: XP_038944046   ⟸   XM_039088118
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000085385   ⟸   ENSRNOT00000117390
Protein Domains
OMPdecase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4QQS7-F1-model_v2 AlphaFold Q4QQS7 1-481 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698196
Promoter ID:EPDNEW_R8721
Type:initiation region
Name:Umps_1
Description:uridine monophosphate synthetase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01170,034,161 - 70,034,221EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311908 AgrOrtholog
BioCyc Gene G2FUF-21136 BioCyc
Ensembl Genes ENSRNOG00000001797 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002450.6 UniProtKB/TrEMBL
  ENSRNOP00000085385 ENTREZGENE
  ENSRNOP00000085385.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002450.7 UniProtKB/TrEMBL
  ENSRNOT00000117390 ENTREZGENE
  ENSRNOT00000117390.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
  3.40.50.2020 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7456468 IMAGE-MGC_LOAD
InterPro Aldolase_TIM UniProtKB/TrEMBL
  OMPdecase_1_core UniProtKB/TrEMBL
  OMPdecase_AS UniProtKB/TrEMBL
  OMPdecase_core UniProtKB/TrEMBL
  Or_phspho_trans UniProtKB/TrEMBL
  Orotate_PribosylTferase UniProtKB/TrEMBL
  PRibTrfase UniProtKB/TrEMBL
  PRTase-like UniProtKB/TrEMBL
  RibuloseP-bd_barrel UniProtKB/TrEMBL
KEGG Report rno:288051 UniProtKB/TrEMBL
MGC_CLONE MGC:116188 IMAGE-MGC_LOAD
NCBI Gene 288051 ENTREZGENE
Pfam OMPdecase UniProtKB/TrEMBL
  Pribosyltran UniProtKB/TrEMBL
PharmGKB UMPS RGD
PhenoGen Umps PhenoGen
PROSITE OMPDECASE UniProtKB/TrEMBL
SMART OMPdecase UniProtKB/TrEMBL
Superfamily-SCOP RibP_bind_barrel UniProtKB/TrEMBL
  SSF53271 UniProtKB/TrEMBL
TIGRFAMs pyrE UniProtKB/TrEMBL
  pyrF UniProtKB/TrEMBL
UniProt F7FPV0_RAT UniProtKB/TrEMBL
  Q4QQS7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Umps  uridine monophosphate synthetase  Umps_predicted  uridine monophosphate synthetase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Umps_predicted  uridine monophosphate synthetase (predicted)      Symbol and Name status set to approved 70820 APPROVED