Umps (uridine monophosphate synthetase) - Rat Genome Database

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Gene: Umps (uridine monophosphate synthetase) Mus musculus
Analyze
Symbol: Umps
Name: uridine monophosphate synthetase
RGD ID: 1323613
MGI Page MGI
Description: Enables orotate phosphoribosyltransferase activity and orotidine-5'-phosphate decarboxylase activity. Involved in 'de novo' UMP biosynthetic process and UDP biosynthetic process. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; limb bud; metanephros; pancreas; and surface ectoderm. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Orthologous to human UMPS (uridine monophosphate synthetase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700095D23Rik; AA408257; AL033308; BB164745; UMP synthase; uridine 5'-monophosphate synthase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,775,152 - 33,787,408 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1633,775,152 - 33,787,408 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381633,954,782 - 33,967,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,954,782 - 33,967,038 (-)Ensemblmm10GRCm38
MGSCv371633,955,098 - 33,967,089 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361633,874,759 - 33,886,750 (-)NCBIMGSCv36mm8
Celera1634,439,142 - 34,451,132 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.26NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-gambogic acid  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
5-fluorouracil  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
azaribine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (ISO)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dibenzofurans  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
flutamide  (ISO)
folic acid  (EXP)
FR900359  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
GSK-J4  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methotrexate  (ISO)
mitomycin C  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nimesulide  (ISO)
ozone  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
pioglitazone  (ISO)
progesterone  (EXP,ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
wogonin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
nucleus  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway. Evans DR and Guy HI, J Biol Chem. 2004 Aug 6;279(32):33035-8. Epub 2004 Apr 19.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Pyrimidine nucleotide synthesis in the rat mammary gland: changes in the lactation cycle and effects of diabetes. Kunjara S, etal., Biochem Med Metab Biol. 1992 Dec;48(3):263-74.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Identification of new SNPs associated with severe toxicity to capecitabine. Pellicer M, etal., Pharmacol Res. 2017 Jun;120:133-137. doi: 10.1016/j.phrs.2017.03.021. Epub 2017 Mar 27.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families. Suchi M, etal., Am J Hum Genet. 1997 Mar;60(3):525-39.
13. Regulation of purine and pyrimidine metabolism by insulin and by resistance to tiazofurin. Weber G, etal., Adv Enzyme Regul. 1985;23:81-99.
Additional References at PubMed
PMID:965379   PMID:2338490   PMID:2419341   PMID:3279416   PMID:3308878   PMID:6154574   PMID:7671812   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861  
PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334   PMID:15782199   PMID:15840001   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:22692683   PMID:24457600  
PMID:25044020   PMID:26059768   PMID:27113764   PMID:28106071   PMID:28378742   PMID:30457570   PMID:32968282   PMID:35987808   PMID:36114006  


Genomics

Comparative Map Data
Umps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,775,152 - 33,787,408 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1633,775,152 - 33,787,408 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381633,954,782 - 33,967,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,954,782 - 33,967,038 (-)Ensemblmm10GRCm38
MGSCv371633,955,098 - 33,967,089 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361633,874,759 - 33,886,750 (-)NCBIMGSCv36mm8
Celera1634,439,142 - 34,451,132 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.26NCBI
UMPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383124,730,452 - 124,749,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3124,730,433 - 124,749,273 (+)Ensemblhg38GRCh38
GRCh373124,449,299 - 124,468,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,931,903 - 125,946,318 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343125,931,902 - 125,946,318NCBI
Celera3122,856,384 - 122,875,279 (+)NCBICelera
Cytogenetic Map3q21.2NCBI
HuRef3121,823,485 - 121,842,386 (+)NCBIHuRef
CHM1_13124,412,201 - 124,431,088 (+)NCBICHM1_1
T2T-CHM13v2.03127,456,263 - 127,475,096 (+)NCBIT2T-CHM13v2.0
Umps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81180,311,269 - 80,321,678 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1180,311,214 - 80,327,828 (+)EnsemblGRCr8
mRatBN7.21166,806,107 - 66,816,520 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,806,045 - 66,821,903 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1175,639,569 - 75,649,990 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,301,455 - 68,311,876 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01167,332,029 - 67,342,450 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01170,034,181 - 70,044,590 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,034,139 - 70,044,628 (+)Ensemblrn6Rnor6.0
Rnor_5.01173,123,827 - 73,134,236 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41168,619,835 - 68,630,244 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1166,256,748 - 66,267,157 (+)NCBICelera
RGSC_v3.11168,677,423 - 68,687,833 (+)NCBI
Cytogenetic Map11q22NCBI
Umps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542723,825,523 - 23,841,152 (+)Ensembl
ChiLan1.0NW_00495542723,825,529 - 23,841,427 (+)NCBIChiLan1.0ChiLan1.0
UMPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22122,691,417 - 122,706,258 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13122,696,194 - 122,711,035 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03121,832,758 - 121,851,707 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13128,731,309 - 128,745,241 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3128,731,355 - 128,745,029 (+)EnsemblpanPan2panpan1.1
UMPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13327,754,592 - 27,782,517 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3327,754,643 - 27,782,514 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3327,778,349 - 27,806,263 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03327,991,347 - 28,019,249 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3327,991,386 - 28,019,245 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13327,786,637 - 27,814,528 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03327,830,936 - 27,858,855 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03328,449,678 - 28,477,605 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Umps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602126,644,830 - 126,656,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936725549,804 - 565,141 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936725553,278 - 564,846 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UMPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13135,610,058 - 135,650,603 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113135,611,857 - 135,650,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,113,405 - 145,154,901 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UMPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12256,081,897 - 56,097,164 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2256,082,103 - 56,097,105 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041110,226,585 - 110,241,588 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Umps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624731761,210 - 779,321 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624731761,235 - 780,355 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Umps
370 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1459
Count of miRNA genes:581
Interacting mature miRNAs:668
Transcripts:ENSMUST00000023510, ENSMUST00000131990
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162879281362792952Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162879281362792952Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162879281362792952Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
25671380Hrsq2_mhost response to SARS QTL 2, titer (mouse)163140250136540273Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3252290965466552Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163231279566312933Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162879281362792952Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
15092062Egrme4_mearly growth rate, maternal effect 4 (mouse)162521866444220250Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
AA408257  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381633,954,922 - 33,955,017UniSTSGRCm38
MGSCv371633,955,008 - 33,955,103UniSTSGRCm37
Celera1634,439,052 - 34,439,147UniSTS
Cytogenetic Map16B3UniSTS
Whitehead/MRC_RH16333.39UniSTS
BB164745  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381633,955,070 - 33,955,156UniSTSGRCm38
MGSCv371633,955,156 - 33,955,242UniSTSGRCm37
Celera1634,439,200 - 34,439,286UniSTS
Cytogenetic Map16B3UniSTS
Whitehead/MRC_RH16333.68UniSTS
RH124201  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381633,956,666 - 33,956,789UniSTSGRCm38
MGSCv371633,956,752 - 33,956,875UniSTSGRCm37
Celera1634,440,796 - 34,440,919UniSTS
Cytogenetic Map16B3UniSTS
RH124692  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381633,954,924 - 33,955,017UniSTSGRCm38
MGSCv371633,955,010 - 33,955,103UniSTSGRCm37
Celera1634,439,054 - 34,439,147UniSTS
Cytogenetic Map16B3UniSTS
UniSTS:237497  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381633,955,274 - 33,955,412UniSTSGRCm38
MGSCv371633,955,360 - 33,955,498UniSTSGRCm37
Celera1634,439,404 - 34,439,542UniSTS
Cytogenetic Map16B3UniSTS
Umps  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B3UniSTS
cM Map1624.26UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001348087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC165079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC095981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM219105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000023510   ⟹   ENSMUSP00000023510
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1633,775,152 - 33,787,408 (-)Ensembl
GRCm38.p6 Ensembl1633,954,782 - 33,967,038 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131990   ⟹   ENSMUSP00000119423
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1633,775,164 - 33,787,373 (-)Ensembl
GRCm38.p6 Ensembl1633,954,794 - 33,967,003 (-)Ensembl
RefSeq Acc Id: NM_001348087   ⟹   NP_001335016
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391633,775,152 - 33,787,408 (-)NCBI
GRCm381633,954,782 - 33,967,038 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009471   ⟹   NP_033497
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391633,775,152 - 33,787,408 (-)NCBI
GRCm381633,954,782 - 33,967,038 (-)NCBI
MGSCv371633,955,098 - 33,967,089 (-)RGD
Celera1634,439,142 - 34,451,132 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033497   ⟸   NM_009471
- Peptide Label: isoform 1
- UniProtKB: Q99L26 (UniProtKB/Swiss-Prot),   P13439 (UniProtKB/Swiss-Prot),   Q544K9 (UniProtKB/TrEMBL),   Q3TVV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001335016   ⟸   NM_001348087
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000119423   ⟸   ENSMUST00000131990
Ensembl Acc Id: ENSMUSP00000023510   ⟸   ENSMUST00000023510
Protein Domains
Orotidine 5'-phosphate decarboxylase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P13439-F1-model_v2 AlphaFold P13439 1-481 view protein structure

Promoters
RGD ID:6827615
Promoter ID:MM_KWN:20835
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000065699,   OTTMUST00000065700
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361633,966,906 - 33,967,412 (-)MPROMDB
RGD ID:8686050
Promoter ID:EPDNEW_M21056
Type:initiation region
Name:Umps_1
Description:Mus musculus uridine monophosphate synthetase , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381633,967,003 - 33,967,063EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1298388 AgrOrtholog
Ensembl Genes ENSMUSG00000022814 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023510 ENTREZGENE
  ENSMUST00000023510.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot
  3.40.50.2020 UniProtKB/Swiss-Prot
InterPro Aldolase_TIM UniProtKB/Swiss-Prot
  OMPdecase UniProtKB/Swiss-Prot
  OMPdecase_AS UniProtKB/Swiss-Prot
  OMPdeCOase_dom UniProtKB/Swiss-Prot
  OPRT UniProtKB/Swiss-Prot
  Or_phspho_trans_dom UniProtKB/Swiss-Prot
  PRibTrfase_dom UniProtKB/Swiss-Prot
  PRTase-like UniProtKB/Swiss-Prot
  RibuloseP-bd_barrel UniProtKB/Swiss-Prot
KEGG Report mmu:22247 UniProtKB/Swiss-Prot
MGD MGI:1298388 ENTREZGENE
NCBI Gene 22247 ENTREZGENE
PANTHER OROTATE PHOSPHORIBOSYLTRANSFERASE UniProtKB/Swiss-Prot
  URIDINE 5'-MONOPHOSPHATE SYNTHASE UniProtKB/Swiss-Prot
Pfam OMPdecase UniProtKB/Swiss-Prot
  Pribosyltran UniProtKB/Swiss-Prot
PharmGKB UMPS RGD
PhenoGen Umps PhenoGen
PROSITE OMPDECASE UniProtKB/Swiss-Prot
  PUR_PYR_PR_TRANSFER UniProtKB/Swiss-Prot
SMART OMPdecase UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51366 UniProtKB/Swiss-Prot
  SSF53271 UniProtKB/Swiss-Prot
UniProt D6RJ62_MOUSE UniProtKB/TrEMBL
  P13439 ENTREZGENE
  Q3TVV7 ENTREZGENE, UniProtKB/TrEMBL
  Q544K9 ENTREZGENE, UniProtKB/TrEMBL
  Q99L26 ENTREZGENE
  UMPS_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q99L26 UniProtKB/Swiss-Prot