UMPS (uridine monophosphate synthetase) - Rat Genome Database
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Gene: UMPS (uridine monophosphate synthetase) Sus scrofa
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Symbol: UMPS
Name: uridine monophosphate synthetase
RGD ID: 14272835
Description: ENCODES a protein that exhibits identical protein binding (ortholog); orotate phosphoribosyltransferase activity (ortholog); orotidine-5'-phosphate decarboxylase activity (ortholog); INVOLVED IN cellular response to drug (ortholog); female pregnancy (ortholog); lactation (ortholog); PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; ASSOCIATED WITH Acute Erythroblastic Leukemia (ortholog); beta thalassemia (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: uridine 5'-monophosphate synthase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13135,610,058 - 135,650,604 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113135,611,857 - 135,650,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,113,405 - 145,154,901 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
UMPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13135,610,058 - 135,650,604 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113135,611,857 - 135,650,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,113,405 - 145,154,901 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UMPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3124,730,433 - 124,749,273 (+)EnsemblGRCh38hg38GRCh38
GRCh383124,730,442 - 124,749,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373124,449,299 - 124,468,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,931,903 - 125,946,318 (+)NCBINCBI36hg18NCBI36
Build 343125,931,902 - 125,946,318NCBI
Celera3122,856,384 - 122,875,279 (+)NCBI
Cytogenetic Map3q21.2NCBI
HuRef3121,823,485 - 121,842,386 (+)NCBIHuRef
CHM1_13124,412,201 - 124,431,088 (+)NCBICHM1_1
Umps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,775,152 - 33,787,408 (-)NCBIGRCm39mm39
GRCm39 Ensembl1633,775,152 - 33,787,408 (-)Ensembl
GRCm381633,954,782 - 33,967,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,954,782 - 33,967,038 (-)EnsemblGRCm38mm10GRCm38
MGSCv371633,955,098 - 33,967,089 (-)NCBIGRCm37mm9NCBIm37
MGSCv361633,874,759 - 33,886,750 (-)NCBImm8
Celera1634,439,142 - 34,451,132 (-)NCBICelera
Cytogenetic Map16B3NCBI
Umps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21166,806,107 - 66,816,520 (+)NCBI
Rnor_6.0 Ensembl1170,034,139 - 70,044,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01170,034,181 - 70,044,590 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01173,123,827 - 73,134,236 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,619,835 - 68,630,244 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11168,677,423 - 68,687,833 (+)NCBI
Celera1166,256,748 - 66,267,157 (+)NCBICelera
Cytogenetic Map11q22NCBI
Umps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542723,825,523 - 23,841,152 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542723,825,529 - 23,841,427 (+)NCBIChiLan1.0ChiLan1.0
UMPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13128,731,309 - 128,745,241 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3128,731,355 - 128,745,029 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03121,832,758 - 121,851,707 (+)NCBIMhudiblu_PPA_v0panPan3
UMPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3327,754,643 - 27,782,514 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13327,754,592 - 27,782,517 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Umps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936725553,278 - 564,846 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UMPS
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12256,081,897 - 56,097,164 (-)NCBI
ChlSab1.1 Ensembl2256,082,103 - 56,097,105 (-)Ensembl
Umps
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624731761,235 - 780,355 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 2 5 2 2 1
Low 5 2 3 2 23 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012978   ⟹   ENSSSCP00000012636
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13135,611,861 - 135,650,604 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000071965   ⟹   ENSSSCP00000068099
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13135,610,058 - 135,650,588 (-)Ensembl
RefSeq Acc Id: XM_021071253   ⟹   XP_020926912
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113135,611,857 - 135,650,656 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020926912 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020926912   ⟸   XM_021071253
- Sequence:
RefSeq Acc Id: ENSSSCP00000012636   ⟸   ENSSSCT00000012978
RefSeq Acc Id: ENSSSCP00000068099   ⟸   ENSSSCT00000071965
Protein Domains
OMPdecase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070010111 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012636 UniProtKB/TrEMBL
  ENSSSCP00000068099 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070016316 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012978 UniProtKB/TrEMBL
  ENSSSCT00000071965 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070019625 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
  3.40.50.2020 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  OMPdecase UniProtKB/TrEMBL
  OMPdecase_AS UniProtKB/TrEMBL
  OMPdeCOase_dom UniProtKB/TrEMBL
  OPRT UniProtKB/TrEMBL
  Or_phspho_trans_dom UniProtKB/TrEMBL
  PRibTrfase_dom UniProtKB/TrEMBL
  PRTase-like UniProtKB/TrEMBL
  RibuloseP-bd_barrel UniProtKB/TrEMBL
NCBI Gene UMPS ENTREZGENE
Pfam OMPdecase UniProtKB/TrEMBL
  Pribosyltran UniProtKB/TrEMBL
PROSITE OMPDECASE UniProtKB/TrEMBL
SMART OMPdecase UniProtKB/TrEMBL
Superfamily-SCOP SSF51366 UniProtKB/TrEMBL
  SSF53271 UniProtKB/TrEMBL
TIGRFAMs pyrE UniProtKB/TrEMBL
  pyrF UniProtKB/TrEMBL
UniProt A0A4X1TM93_PIG UniProtKB/TrEMBL
  A0A5G2RBV3_PIG UniProtKB/TrEMBL
  F1SQ55_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94700 ENTREZGENE