Gart (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase) - Rat Genome Database

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Gene: Gart (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase) Rattus norvegicus
Analyze
Symbol: Gart
Name: phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
RGD ID: 1308717
Description: Enables phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity; and phosphoribosylglycinamide formyltransferase activity. Involved in brainstem development; cerebellum development; and cerebral cortex development. Predicted to be active in cytosol. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC288259; phosphoribosylglycinamide formyltransferase; trifunctional purine biosynthetic protein adenosine-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,351,841 - 44,377,086 (-)NCBIGRCr8
mRatBN7.21130,864,896 - 30,891,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,865,889 - 30,891,125 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1139,559,784 - 39,585,049 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,231,220 - 32,256,482 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,396,470 - 31,421,682 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01131,780,477 - 31,805,728 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,780,487 - 31,805,728 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01135,389,216 - 35,414,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,594,859 - 31,620,110 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,646,660 - 31,659,129 (-)NCBI
Celera1130,533,312 - 30,558,557 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-fluorouracil  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
pyrogallol  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development and temporally overexpressed in cerebellum of individuals with Down syndrome. Brodsky G, etal., Hum Mol Genet. 1997 Nov;6(12):2043-50.
2. Characterization of mammalian phosphoribosylglycineamide formyltransferase from transformed cells. Daubner SC and Benkovic SJ, Cancer Res. 1985 Oct;45(10):4990-7.
3. Effect of cobalamin inactivation on folate-dependent transformylases involved in purine synthesis in rats. Deacon R, etal., Biochem J. 1985 Apr 1;227(1):67-71.
4. Role of folate dependent transformylases in synthesis of purine in bone marrow of man and in bone marrow and liver of rats. Deacon R, etal., J Clin Pathol. 1985 Dec;38(12):1349-52.
5. Developmental changes in the folate-dependent enzymes of de novo purine biosynthesis in rat brain. Dominguez J and Ordonez LA, J Neurochem. 1982 Mar;38(3):625-30.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Purification of mammalian glycinamide ribonucleotide (GAR) synthetase. Hards RG, etal., Adv Exp Med Biol. 1986;195 Pt B:315-9.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Trafficking of intracellular folates. Stover PJ and Field MS, Adv Nutr. 2011 Jul;2(4):325-31. doi: 10.3945/¿an.111.000596. Epub 2011 Jun 28.
15. Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GAR. Zhang Y, etal., Biochemistry 2002 Dec 3;41(48):14206-15.
Additional References at PubMed
PMID:12477932   PMID:20458337   PMID:24709117  


Genomics

Comparative Map Data
Gart
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,351,841 - 44,377,086 (-)NCBIGRCr8
mRatBN7.21130,864,896 - 30,891,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,865,889 - 30,891,125 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1139,559,784 - 39,585,049 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,231,220 - 32,256,482 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,396,470 - 31,421,682 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01131,780,477 - 31,805,728 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,780,487 - 31,805,728 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01135,389,216 - 35,414,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,594,859 - 31,620,110 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,646,660 - 31,659,129 (-)NCBI
Celera1130,533,312 - 30,558,557 (-)NCBICelera
Cytogenetic Map11q11NCBI
GART
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382133,503,931 - 33,542,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2133,503,931 - 33,543,491 (-)EnsemblGRCh38hg38GRCh38
GRCh372134,876,238 - 34,915,198 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,798,139 - 33,836,286 (-)NCBINCBI36Build 36hg18NCBI36
Build 342133,818,186 - 33,836,286NCBI
Celera2120,075,872 - 20,114,832 (-)NCBICelera
Cytogenetic Map21q22.11ENTREZGENE
HuRef2120,354,547 - 20,393,666 (-)NCBIHuRef
CHM1_12134,438,919 - 34,477,881 (-)NCBICHM1_1
T2T-CHM13v2.02131,885,765 - 31,924,746 (-)NCBIT2T-CHM13v2.0
Gart
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,418,283 - 91,444,505 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,418,074 - 91,443,840 (-)EnsemblGRCm39 Ensembl
GRCm381691,621,395 - 91,646,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,621,186 - 91,646,952 (-)EnsemblGRCm38mm10GRCm38
MGSCv371691,621,640 - 91,647,217 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361691,510,268 - 91,535,812 (-)NCBIMGSCv36mm8
Celera1692,698,203 - 92,723,705 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1653.18NCBI
Gart
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540732,944,164 - 32,973,863 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540732,944,638 - 32,975,142 (-)NCBIChiLan1.0ChiLan1.0
GART
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22229,622,168 - 29,660,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12124,479,281 - 24,520,421 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02119,871,656 - 19,909,893 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12133,244,457 - 33,282,709 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2133,244,457 - 33,282,331 (-)Ensemblpanpan1.1panPan2
LOC487740
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13129,032,399 - 29,063,706 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gart
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497128,685,224 - 28,715,394 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365008,753,463 - 8,786,236 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365008,750,928 - 8,782,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GART
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13197,130,904 - 197,161,891 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113197,130,898 - 197,158,797 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213206,941,099 - 206,971,945 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GART
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,641,566 - 58,682,014 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl258,643,877 - 58,683,023 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660711,144,831 - 1,183,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gart
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474521,734,282 - 21,762,734 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474521,735,431 - 21,763,330 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gart
128 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:118
Interacting mature miRNAs:130
Transcripts:ENSRNOT00000032162
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat

Markers in Region
RH140539  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,878,931 - 30,879,108 (+)MAPPERmRatBN7.2
Rnor_6.01131,793,535 - 31,793,711NCBIRnor6.0
Rnor_5.01135,402,268 - 35,402,444UniSTSRnor5.0
RGSC_v3.41131,607,917 - 31,608,093UniSTSRGSC3.4
Celera1130,546,364 - 30,546,540UniSTS
RH 3.4 Map11176.8UniSTS
Cytogenetic Map11q11UniSTS
REN85607  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,880,554 - 30,880,937 (+)MAPPERmRatBN7.2
Rnor_6.01131,795,158 - 31,795,540NCBIRnor6.0
Rnor_5.01135,403,891 - 35,404,273UniSTSRnor5.0
RGSC_v3.41131,609,540 - 31,609,922UniSTSRGSC3.4
Celera1130,547,987 - 30,548,369UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 46 30 19 30 8 11 74 35 41 11 8
Low 11 11 11
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000032162   ⟹   ENSRNOP00000033253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1130,865,889 - 30,891,125 (-)Ensembl
Rnor_6.0 Ensembl1131,780,487 - 31,805,728 (-)Ensembl
RefSeq Acc Id: NM_001011899   ⟹   NP_001011899
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,351,841 - 44,377,086 (-)NCBI
mRatBN7.21130,865,879 - 30,891,125 (-)NCBI
Rnor_6.01131,780,477 - 31,805,728 (-)NCBI
Rnor_5.01135,389,216 - 35,414,461 (-)NCBI
RGSC_v3.41131,594,859 - 31,620,110 (-)RGD
Celera1130,533,312 - 30,558,557 (-)RGD
Sequence:
RefSeq Acc Id: XM_017597941   ⟹   XP_017453430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,351,841 - 44,377,000 (-)NCBI
mRatBN7.21130,864,896 - 30,891,049 (-)NCBI
Rnor_6.01131,780,477 - 31,805,629 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001011899 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453430 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87644 (Get FASTA)   NCBI Sequence Viewer  
  AAI68661 (Get FASTA)   NCBI Sequence Viewer  
  EDM10733 (Get FASTA)   NCBI Sequence Viewer  
  EDM10734 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033253.4
RefSeq Acc Id: NP_001011899   ⟸   NM_001011899
- UniProtKB: G3V918 (UniProtKB/TrEMBL),   A6JLG8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453430   ⟸   XM_017597941
- Peptide Label: isoform X1
- UniProtKB: G3V918 (UniProtKB/TrEMBL),   A6JLG8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033253   ⟸   ENSRNOT00000032162
Protein Domains
ATP-grasp

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V918-F1-model_v2 AlphaFold G3V918 1-1010 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698059
Promoter ID:EPDNEW_R8584
Type:multiple initiation site
Name:Gart_1
Description:phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamidesynthetase, phosphoribosylaminoimidazole synthetase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01131,805,716 - 31,805,776EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308717 AgrOrtholog
BioCyc Gene G2FUF-21877 BioCyc
Ensembl Genes ENSRNOG00000028292 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032162.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.10 UniProtKB/TrEMBL
  3.30.1490.20 UniProtKB/TrEMBL
  3.40.50.20 UniProtKB/TrEMBL
  3.90.600.10 UniProtKB/TrEMBL
  3.90.650.10 UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/TrEMBL
  Formyl transferase, N-terminal domain UniProtKB/TrEMBL
InterPro AIR_synth_C_dom UniProtKB/TrEMBL
  ATP-grasp UniProtKB/TrEMBL
  ATP_grasp_subdomain_1 UniProtKB/TrEMBL
  Formyl_transf_N UniProtKB/TrEMBL
  Formyl_transf_N_sf UniProtKB/TrEMBL
  GART_AS UniProtKB/TrEMBL
  PreATP-grasp-like UniProtKB/TrEMBL
  PRibGlycinamid_synth_ATP-grasp UniProtKB/TrEMBL
  PRibGlycinamide_synth UniProtKB/TrEMBL
  PRibGlycinamide_synth_C-dom UniProtKB/TrEMBL
  PRibGlycinamide_synth_C_sf UniProtKB/TrEMBL
  PRibGlycinamide_synth_CS UniProtKB/TrEMBL
  PRibGlycinamide_synth_N UniProtKB/TrEMBL
  PurM-like_C_sf UniProtKB/TrEMBL
  PurM-like_N_sf UniProtKB/TrEMBL
  PurM_cligase UniProtKB/TrEMBL
  PurM_N-like UniProtKB/TrEMBL
  PurN_trans UniProtKB/TrEMBL
  Rudment_hybrid_motif UniProtKB/TrEMBL
KEGG Report rno:288259 UniProtKB/TrEMBL
NCBI Gene 288259 ENTREZGENE
PANTHER PTHR10520 UniProtKB/TrEMBL
  TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 UniProtKB/TrEMBL
Pfam AIRS UniProtKB/TrEMBL
  AIRS_C UniProtKB/TrEMBL
  Formyl_trans_N UniProtKB/TrEMBL
  GARS_A UniProtKB/TrEMBL
  GARS_C UniProtKB/TrEMBL
  GARS_N UniProtKB/TrEMBL
PharmGKB GART RGD
PhenoGen Gart PhenoGen
PROSITE ATP_GRASP UniProtKB/TrEMBL
  GARS UniProtKB/TrEMBL
  GART UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028292 RatGTEx
SMART GARS_A UniProtKB/TrEMBL
  GARS_C UniProtKB/TrEMBL
Superfamily-SCOP AIR_synth_C UniProtKB/TrEMBL
  formyl_transf UniProtKB/TrEMBL
  Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
  PreATP-grasp-like UniProtKB/TrEMBL
  Rudmnt_hyb_motif UniProtKB/TrEMBL
  SSF55326 UniProtKB/TrEMBL
UniProt A6JLG8 ENTREZGENE, UniProtKB/TrEMBL
  A6JLG9_RAT UniProtKB/TrEMBL
  B5DEG6_RAT UniProtKB/TrEMBL
  G3V918 ENTREZGENE, UniProtKB/TrEMBL
  Q5PPK3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-07 Gart  phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase  Gart  phosphoribosylglycinamide formyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Gart  phosphoribosylglycinamide formyltransferase  Gart_predicted  phosphoribosylglycinamide formyltransferase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gart_predicted  phosphoribosylglycinamide formyltransferase (predicted)      Symbol and Name status set to approved 70820 APPROVED