Bp388 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp388 (Blood pressure QTL 388) Rattus norvegicus

Symbol: Bp388
Name: Blood pressure QTL 388
RGD ID: 10755497
Previously known as: BP-pm2
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 2.76
P Value: Not Available
Variance: 9.0
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01119,475,179 - 79,734,728RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01123,121,623 - 80,995,502RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41119,938,964 - 78,447,949RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: SR/JrHsd SS/JrHsd 



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
SR/JrHsd  (IEA)
SS/JrHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Differential genetic basis for pre-menopausal and post-menopausal salt-sensitive hypertension. Herrera VL, etal., PLoS One. 2012;7(8):e43160. doi: 10.1371/journal.pone.0043160. Epub 2012 Aug 17.
Related QTLs

Related QTL Description Reference
BP51_H maps to syntenic region RGD:10755344


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (rs107338789)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01119,475,179 - 19,475,179RGD
Rnor_5.01123,121,623 - 23,121,623RGD
RGSC_v3.41119,938,964 - 19,938,964RGD
Flank 2: (rs66115015)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01179,734,728 - 79,734,728RGD
Rnor_5.01180,995,502 - 80,995,502RGD
RGSC_v3.41178,447,949 - 78,447,949RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 130 F2 females 10755344
qtl_general software used: Map Manager QTXb19 10755344
qtl_general to confirm post-menopausal status, vaginal smears were done to determine the estrous cycle stage 10755344
qtl_general measurement method: 8% NaCl diet was started at 14 weeks of age and given for 4 weeks; non-stressed blood pressure measurements were taken by intra-aortic abdominal radiotelemetric implants over 10 seconds every 5 minutes for 24 hours 10755344
qtl_general region spans 48-68 Mbp 10755344