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Gene: Gabpa (GA binding protein transcription factor subunit alpha) Rattus norvegicus

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Symbol:

Gabpa

Name:

GA binding protein transcription factor subunit alpha

RGD ID:

1310802

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within blastocyst formation; negative regulation of megakaryocyte differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleoplasm. Predicted to be active in nucleus. Orthologous to human GABPA (GA binding protein transcription factor subunit alpha); INTERACTS WITH (R)-noradrenaline; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

GA binding protein transcription factor, alpha subunit; GA binding protein transcription factor, alpha subunit 60kDa; GA repeat binding protein, alpha; GA-binding protein alpha chain; Nrf-2alpha; Nrf2a; nuclear respiratory factor 2 alpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	37,375,040 - 37,404,060 (+)	NCBI		GRCr8
mRatBN7.2	11	23,888,586 - 23,917,612 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	23,888,815 - 23,917,605 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	32,595,055 - 32,623,871 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	25,295,462 - 25,324,280 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	24,484,169 - 24,512,986 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	24,293,845 - 24,322,822 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	24,263,281 - 24,322,815 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	27,889,614 - 27,950,063 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	24,323,963 - 24,352,754 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	24,323,497 - 24,350,449 (+)	NCBI
Celera	11	23,728,006 - 23,756,794 (+)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R)-noradrenaline (EXP)

1,2-dimethylhydrazine (ISO)

1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

2-tert-butylhydroquinone (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

anthra[1,9-cd]pyrazol-6(2H)-one (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

caffeine (ISO)

carbon monoxide (EXP,ISO)

chlorpyrifos (ISO)

clorgyline (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

CU-O LINKAGE (ISO)

deoxynivalenol (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

ethanol (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gallic acid (ISO)

gentamycin (EXP)

ivermectin (ISO)

lithium atom (EXP)

lithium hydride (EXP)

LY294002 (EXP)

methamphetamine (EXP)

methapyrilene (EXP)

N,N-diethyl-m-toluamide (EXP)

ozone (ISO)

paracetamol (ISO)

PCB138 (EXP)

permethrin (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

progesterone (EXP)

quercetin (EXP)

rac-lactic acid (ISO)

raloxifene (ISO)

resveratrol (EXP,ISO)

SB 203580 (ISO)

SB 431542 (ISO)

sodium fluoride (ISO)

T-2 toxin (EXP)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

valproic acid (EXP,ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst formation (IEA,ISO)

cell differentiation (IBA)

in utero embryonic development (IEA,ISO)

negative regulation of megakaryocyte differentiation (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

Cellular Component

chromatin (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

chromatin binding (IEA,ISO)

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA,ISO)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (IEA,ISO)

transcription cis-regulatory region binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9857059	PMID:11004506	PMID:12618435	PMID:12750007	PMID:15016074	PMID:15361867	PMID:16757682	PMID:17485447	PMID:22306510	PMID:22780989	PMID:24136195	PMID:24501276
PMID:25783764	PMID:26095579	PMID:27683241	PMID:27869233

Genomics

Comparative Map Data

Gabpa
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	37,375,040 - 37,404,060 (+)	NCBI		GRCr8
mRatBN7.2	11	23,888,586 - 23,917,612 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	23,888,815 - 23,917,605 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	32,595,055 - 32,623,871 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	25,295,462 - 25,324,280 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	24,484,169 - 24,512,986 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	24,293,845 - 24,322,822 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	24,263,281 - 24,322,815 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	27,889,614 - 27,950,063 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	24,323,963 - 24,352,754 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	24,323,497 - 24,350,449 (+)	NCBI
Celera	11	23,728,006 - 23,756,794 (+)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

GABPA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	25,734,972 - 25,772,460 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	25,734,570 - 25,772,460 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	27,107,283 - 27,144,771 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	26,029,570 - 26,066,213 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	26,029,569 - 26,066,210	NCBI
Celera	21	12,290,744 - 12,328,186 (+)	NCBI		Celera
Cytogenetic Map	21	q21.3	ENTREZGENE
HuRef	21	12,510,390 - 12,547,831 (+)	NCBI		HuRef
CHM1_1	21	26,667,879 - 26,705,392 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	24,092,535 - 24,130,020 (+)	NCBI		T2T-CHM13v2.0

Gabpa
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	84,631,795 - 84,660,671 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	84,631,813 - 84,660,667 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	84,834,891 - 84,863,783 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	84,834,925 - 84,863,779 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	84,835,369 - 84,864,024 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	84,717,716 - 84,746,371 (+)	NCBI		MGSCv36	mm8
Celera	16	85,040,521 - 85,069,183 (+)	NCBI		Celera
Cytogenetic Map	16	C3.3	NCBI
cM Map	16	46.92	NCBI

Gabpa
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	25,609,972 - 25,641,879 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	25,609,840 - 25,641,886 (+)	NCBI	ChiLan1.0	ChiLan1.0

GABPA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	21,929,918 - 21,967,759 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	16,787,098 - 16,824,941 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	12,179,921 - 12,217,851 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	25,536,297 - 25,574,871 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	25,536,750 - 25,574,871 (+)	Ensembl	panpan1.1		panPan2

GABPA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	21,216,931 - 21,251,658 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	21,216,710 - 21,248,792 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	21,212,185 - 21,246,275 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	21,269,741 - 21,305,499 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	21,270,279 - 21,305,621 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	21,287,826 - 21,323,587 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	21,289,044 - 21,324,795 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	21,764,481 - 21,800,239 (+)	NCBI		UU_Cfam_GSD_1.0

Gabpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	21,764,316 - 21,798,893 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936640	1,882,238 - 1,914,232 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936640	1,882,297 - 1,917,210 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GABPA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	189,289,996 - 189,327,497 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	189,289,513 - 189,327,501 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	199,168,101 - 199,183,080 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GABPA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	66,502,250 - 66,539,436 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	66,505,401 - 66,539,791 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	87,015,407 - 87,052,849 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gabpa
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	13,788,288 - 13,821,599 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	13,787,352 - 13,820,781 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gabpa
12 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	224
Count of miRNA genes:	172
Interacting mature miRNAs:	188
Transcripts:	ENSRNOT00000002115
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
1598842	Glom10	Glomerulus QTL 10	3.4		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	1	35331169	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	19456205	76331918	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	16472047	44285911	Rat
2290451	Scl58	Serum cholesterol level QTL 58	3.48		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	11	12831046	25121472	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
1600394	Edcs1	Endometrial carcinoma susceptibility QTL1	2.9	0.04	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	11	18976208	24697116	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
1641927	Alcrsp10	Alcohol response QTL 10			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	11	8436674	53436674	Rat

Markers in Region

BF387369

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,861,495 - 23,861,668 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,266,715 - 24,266,887	NCBI	Rnor6.0
Rnor_5.0	11	27,894,504 - 27,894,676	UniSTS	Rnor5.0
Celera	11	23,700,703 - 23,700,875	UniSTS
RH 3.4 Map	11	113.0	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH130478

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,881,659 - 23,882,218 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,286,872 - 24,287,430	NCBI	Rnor6.0
Rnor_5.0	11	27,914,868 - 27,915,426	UniSTS	Rnor5.0
RGSC_v3.4	11	24,316,811 - 24,317,369	UniSTS	RGSC3.4
Celera	11	23,720,852 - 23,721,410	UniSTS
RH 3.4 Map	11	102.1	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH130790

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,879,704 - 23,879,909 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,284,917 - 24,285,121	NCBI	Rnor6.0
Rnor_5.0	11	27,912,913 - 27,913,117	UniSTS	Rnor5.0
RGSC_v3.4	11	24,314,857 - 24,315,061	UniSTS	RGSC3.4
Celera	11	23,718,897 - 23,719,101	UniSTS
RH 3.4 Map	11	105.9	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH133736

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	11	37,365,168 - 37,365,378 (+)	Marker Load Pipeline
mRatBN7.2	11	23,878,718 - 23,878,928 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,283,931 - 24,284,140	NCBI	Rnor6.0
Rnor_5.0	11	27,911,927 - 27,912,136	UniSTS	Rnor5.0
RGSC_v3.4	11	24,313,871 - 24,314,080	UniSTS	RGSC3.4
Celera	11	23,717,911 - 23,718,120	UniSTS
RH 3.4 Map	11	108.1	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH143705

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,877,444 - 23,877,563 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,282,657 - 24,282,775	NCBI	Rnor6.0
Rnor_5.0	11	27,910,653 - 27,910,771	UniSTS	Rnor5.0
RGSC_v3.4	11	24,312,597 - 24,312,715	UniSTS	RGSC3.4
Celera	11	23,716,637 - 23,716,755	UniSTS
RH 3.4 Map	11	99.2	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH143804

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,885,690 - 23,885,938 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,290,903 - 24,291,150	NCBI	Rnor6.0
Rnor_5.0	11	27,918,899 - 27,919,145	UniSTS	Rnor5.0
RGSC_v3.4	11	24,320,842 - 24,321,087	UniSTS	RGSC3.4
Celera	11	23,724,883 - 23,725,130	UniSTS
RH 3.4 Map	11	142.28	UniSTS
Cytogenetic Map	11	q11	UniSTS

JAM2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,876,888 - 23,877,010 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,282,101 - 24,282,222	NCBI	Rnor6.0
Rnor_5.0	11	27,910,097 - 27,910,218	UniSTS	Rnor5.0
RGSC_v3.4	11	24,312,041 - 24,312,162	UniSTS	RGSC3.4
Celera	11	23,716,081 - 23,716,202	UniSTS
Cytogenetic Map	11	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000086946 ⟹ ENSRNOP00000071293

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	23,888,815 - 23,917,605 (+)	Ensembl
Rnor_6.0 Ensembl	11	24,263,281 - 24,322,815 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103216 ⟹ ENSRNOP00000097612

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	23,894,681 - 23,917,605 (+)	Ensembl

RefSeq Acc Id:

NM_001108841 ⟹ NP_001102311

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,375,264 - 37,404,053 (+)	NCBI
mRatBN7.2	11	23,888,815 - 23,917,605 (+)	NCBI
Rnor_6.0	11	24,294,026 - 24,322,815 (+)	NCBI
Rnor_5.0	11	27,889,614 - 27,950,063 (+)	NCBI
RGSC_v3.4	11	24,323,963 - 24,352,754 (+)	RGD
Celera	11	23,728,006 - 23,756,794 (+)	RGD

Sequence:

show sequence

GCATGCGTGCTTTGGCCTGTCCCCTAATTCAAGCTCCCTACGGAGTCAACGTCCTGATCCTTGG
GGTTGGGGAGGTGGATGTAATGTGGGGTAAAACGAGCGCGTAAAACAAAGCGGCTTGGGGCGTT
TGTGCCTCGCGAGCCCCCGTTGTCACGGGCGTTCGTGTCGCGCAGCCTGCTGGGAGTTGTAGTT
CCAGGCCCAGGGGTGCCTGGGAGGCGGGAGAGGGGCTGGGGTTCCTTAGCGCCGATTCCGCGGG
AAGGGCCCCGGGGCCTCACACTGCTACTCGCGGGACCGGCGCGTCTTACCCAGAGAGACGCTGT
ACCTGGAGCCCGCGCCGCCGCCGTTCCCAGCCGGCTCTGGAGCGCGGGCGAGGGCCACGGGGCG
GATTCCGGAGCTGGACTGAACTTTTGAAATACTTCCACCATGACTAAGAGAGAAGCAGAAGAAC
TGATAGAGATTGAGATCGATGGGACTGAGAAACCGGAGTGCACAGAAGAAAGCATTGTGGAACA
AACCTATGCCCCAGCTGAGTGTGTAAGCCAGGCCATAGACATCAATGAACCAATAGGCAATTTA
AAGAAGCTATTAGAACCAAGACTGCAGTGCTCTTTGGATGCTCATGAAATTTGCCTACAAGATA
TTCAGCTGGATCCAGACCGAAGTTTGTTTGATCAAGGAGTGAAAACAGATGGGACTGTACAGCT
TAGTGTACAGGTAATTTCTTACCAAGGAATTGAACCAAAGTTAAACATTCTTGAAATTGTTAAG
ACTGCAGAAACAGTTGAAGTGGTCATTGATCCAGATGCCCACCATGCAGAAGCAGAAGCACATC
TCGTTGAAGAAGCTCAAGTGATAACTCTTGACGGCACCAAGCATATCACAACCATTTCAGATGA
GACCTCAGAGCAAGTGACGAGATGGGCCGCTGCACTGGAAGGCTACAGAAAAGAGCAGGAGCGC
CTCGGGATCCCCTATGATCCTATACAGTGGTCCACAGACCAAGTCCTGCATTGGGTGGTTTGGG
TAATGAAGGAGTTCAGCATGACTGATATAGACCTCACCACACTCAACATTTCGGGAAGAGAATT
ATGTAGTCTCAACCAAGAAGATTTTTTTCAGCGGGTCCCTCGGGGAGAAATTCTCTGGAGTCAT
CTGGAGCTTCTTCGAAAATATGTTTTGGCAAGCCAAGAGCAACAGATGAATGAGATAGTTACAA
TTGACCAGCCTGTGCAAATTATTCCAGCATCAGTGCCTTCTGCTACGCCGACTACTATTAAGGT
TATAAACAGTAGCGCAAAGGCAGCTAAAGTTCAAAGGTCCCCAAGGATCTCAGGAGAAGATAGG
AGCTCACCGGGGAACAGAACAGGAAACAATGGTCAGATCCAACTATGGCAGTTTTTGCTTGAAC
TTCTTACTGACAAGGATGCTCGAGACTGTATTTCTTGGGTTGGTGATGAAGGGGAATTCAAGCT
AAATCAGCCTGAATTAGTTGCACAAAAATGGGGACAACGTAAAAACAAGCCTACAATGAACTAT
GAGAAACTTAGCCGTGCATTACGGTATTATTATGATGGGGACATGATTTGTAAAGTTCAAGGCA
AGAGATTTGTGTACAAATTTGTCTGTGACTTGAAGACTCTGATTGGATACAGTGCAGCGGAACT
GAACCGCTTGGTCACAGAATGTGAACAGAAGAAGCTTGCCAAGATGCAGCTCCACGGGATTGCT
CAGCCAGTCACAGCCGTGGCACTGGCTGCTGCCTCTCTCCAGACAGAAAAGGACAATTGAGATC
TAGGACCTCCTGAGAAGTCTTAAGGTTTTTCTTAAATATTTAGAGCAAGCTTTGCTCTAACATT
TATTACTGAATTTGAATCTTATTTCTAGAGTGTACAATCTGATGCATGATTTTTTATAAATATT
TCATACTCTTGTGAATTTGAATCTTTTTACGTTGAGCATATATTTTAGAATATGTTAAAGGATC
ACCACGATGCCTGCAGGCGAGAGCAGGTTCATCGGGGGTAGTTTGCTAACAGTCAGGAAAGCTA
AACTGGTCAGTATTAATGTCTACCCTACCAAAAAATAGCCAGGAGCGTCTGAAGATGACAGTAA
GGAAGCATTTCCAGAAAGCAGCCTGGAGTAGCCACTGCTGGAGTGTAGCTGTTTCCTCTCTGCT
GCTTTACATAGAGCCTGAAAAGGGAATTTTCAGCTAAAGCATGTGTGCCTGTTTCATCTAATCA
AGCAGAGCTAAACAGTCATATCAAATAAAATTATATGATAATTGCTAAACTATCAGGTTATTAA
TTTATATATTTGCAAGTAAAAAATAAGTTAACTGGCAGAAGAAAGTGTTGAATGAGACCCAGGT
TTAAAGCTGGCTTAACTCAAACCATTATTAATGGTTTCTGTGTAGATTACTCATTATGTCAAGC
CAAGGACTTAAATTATTTTGAGAGAGGCATTTAATTCTAATAAACCAGCTATTGCAAAAATTTC
AAAATGATATCTTTTTTTTCTCTCAGACTTTAAAGTATACCTCAGTTAGAAAGAAGAAATTGGT
TTAGTTTTGACTTCCTCTTTTTTAAGAATTAATCTATGGTACCAGATTATTATGCAACACCATT
TATATATTCTCTTCTGTGTTTCTGATAAAATGAAGACTTTAGATCAGATGAAAGTGTTTAAGGT
TTGAAGTAAGTTCCTTGTGAATAGTTATGAAAGGGTGTTTGCCTGGGCTCTGTAGGAGATCTTC
TTTAAATAAAGTTTCCCACTTGTTTCATTTTTTTCTTTTGAATATTGCATATATGACTCTAAAA
ATACTATACACACGGCTAGCTAACCACTTTCTACATATATGAAGACAAAGTTATTCAAGGGGAG
ATTAATATTTCTAAAATCTTTAAATCTTATATGAAATGCCTTACTGCTTGCTAACACTAAGAAG
AAATGGCTTGAAAAGTCTTGTTTATTTTAAAGTATTATCCGTAAATCATGATATGAGAGATTAG
CATATAGTTTTCATAACAGAAAGGAATTCCTCAGAGCGGTATAAAGGCTACTTTATGTACACCT
CTCATTTGTTTTTCTTTCAATTCATTCCCAAATTGGCTTTAGAAGAGTTGATGAGGAGAGAAAG
CACATGCAGTTGCAGCCTGATGGTGCGGCTTGGAGTATTAGGGAGGAGAAAGAAGGGTTGCTTA
CCTCCTACAGCGTAACGTCCAGTGCCGGGCTGTCAGGCTTCAAGTGTGGCCAGCGTCTTTATAT
TAAGTCCTTTAAGATTATACAGGAAGTAGTTAGAGTTAAGTTGGATCTTTTACTTTTGCTTGTA
TGTATGTGTGTAGGTACACACACACACACACACACACACACACACACACACACACACACGCACG
CACGCACGCACGCACGCACACGCACGCACACACAACAGTAGGCTGGCAATTATTCGTACAATTT
GCTCACCGTGATTTGAAGACTGTAGACTCTTAGAACAATCTCTAGGCCTTGACTTCAGATGACA
ATTAGGTTCTCCCCATCTCAGAAAGTCTGGGGAGCCATAACTCACTGCTTCAAAACAGAAGATT
TTCATAGTCCATCAGAGCTTGAGAATCTTAGAGTTACAATGTTTTAGCCAAGAGGACAGACTTT
GTGTATCATTCAGAGAAATATGTTTTTAAGGAAAGGAACATTTTTATTTGTTCTAGGTCCCTAA
AATCAAATTAAACATGTCCAAATGCTTTAAAAAACAAAACAAAACACAAAGCTGGCTTCTGTAG
ATTGCTCTCCTCAGAAGCTGTTGTTTGCTGTGTTTTGAGCACAGGTCTCAGACATGAGCTGCTC
GTTCTCTTCAGCCCGTGTCCTTCCATCCACTTCACACAGGATGTGGAAGGGCTTCTCCCTGACT
CAGCGCTATTACTCTGTCTCCACCTAGACTTAAAAGTATTTGTTACTTTTGAGGCCACAGTTTG
CTATCTTCTATTAAAACAAGTCATGTTATAAAAGAATATTAACCCGTGGTATTCCTTGCTCAGT
TTTGTTGTGCATTTTTCATAGATCATAAGATACAGTTAAACGAAAACATCAGAAAACTGACCAT
CTTTTGTACCTTGTAAGTTCAATTATAATGAAATGTTCATTTTGTTAGGAAGGTTTTCCGTGTG
ATGTTTACATTGAGCTCATTCTATACGTGTGCTGGCCTGAAGTCTGACCAGTTGTGCCAGCATT
TTGCAAAGTCCCTTAGGGAGGCAGAAGTCCTAGGTGTGGCTGAGCTCCACATGATGGGTTAACC
AATTACAGTCATTTTGGTGTTGATCCATGTAAATAAAGTAGGAAAAATTATTCAATTTTTCTCC
CCAGGTAAGCAGTGATGCTCGAGTATGGTTATTTCTTTTAAAGAGTGTACCTCCAAATATTTTT
GGCAAGTTCTGTCATTTTCTGCATTTGCCATTTATGCTACTGCCTTTTATAAAGAACTAGTGTA
TCCTTGAAATAGCACAAAAAATGTTTTAAAATTTATAATTGCAAAACAAACCTGTGACTGACTT
AATGTCCTCAGATAAAGGCTATAAAAATGTTGATATTTCACTTATTCCCAAGAAAAAAAAATAC
TCTCAGTCTTTTGTAGAAGAGAGGAGAGTTTTTGCATACATTTTTACTCTTTAAATAAAGACAC
TTATACTATCATAATAACAATTATGTATTTCTTTGTTTTTTTGTAATTTTACATAAAACAGTTA
TTTTCTATTTTTACTCAGATAAATATTTGTGCATAAAATGTAAAAATAGTAAATGAGAAAAATA
AACTATTATACAATAAATTCTTATGTTG

hide sequence

RefSeq Acc Id:

XM_063270664 ⟹ XP_063126734

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,375,040 - 37,404,060 (+)	NCBI

RefSeq Acc Id:

XM_063270665 ⟹ XP_063126735

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,375,960 - 37,404,060 (+)	NCBI

RefSeq Acc Id:

XM_063270666 ⟹ XP_063126736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,375,522 - 37,404,060 (+)	NCBI

RefSeq Acc Id:

XM_063270667 ⟹ XP_063126737

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,375,040 - 37,404,060 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102311	(Get FASTA)	NCBI Sequence Viewer
	XP_063126734	(Get FASTA)	NCBI Sequence Viewer
	XP_063126735	(Get FASTA)	NCBI Sequence Viewer
	XP_063126736	(Get FASTA)	NCBI Sequence Viewer
	XP_063126737	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10625	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071293
	ENSRNOP00000071293.1
	ENSRNOP00000097612.1
	ENSRNOP00000099854

RefSeq Acc Id:

NP_001102311 ⟸ NM_001108841

- UniProtKB:

D4ACQ9 (UniProtKB/TrEMBL), A6JL60 (UniProtKB/TrEMBL), A0A8I6GML2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTKREAEELIEIEIDGTEKPECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQCSLD
AHEICLQDIQLDPDRSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKTAETVEVVIDPDA
HHAEAEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTD
QVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEILWSHLELLRKYVLASQE
QQMNEIVTIDQPVQIIPASVPSATPTTIKVINSSAKAAKVQRSPRISGEDRSSPGNRTGNNGQI
QLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDG
DMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVALAAASL
QTEKDN

hide sequence

Ensembl Acc Id:

ENSRNOP00000071293 ⟸ ENSRNOT00000086946

Ensembl Acc Id:

ENSRNOP00000097612 ⟸ ENSRNOT00000103216

RefSeq Acc Id:	XP_063126734 ⟸ XM_063270664
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GML2 (UniProtKB/TrEMBL), A6JL60 (UniProtKB/TrEMBL), D4ACQ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063126737 ⟸ XM_063270667
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GML2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063126736 ⟸ XM_063270666
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GML2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063126735 ⟸ XM_063270665
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GML2 (UniProtKB/TrEMBL), A6JL60 (UniProtKB/TrEMBL), D4ACQ9 (UniProtKB/TrEMBL)

Protein Domains

ETS PNT

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ACQ9-F1-model_v2	AlphaFold	D4ACQ9	1-454	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310802	AgrOrtholog
BioCyc Gene	G2FUF-22081	BioCyc
Ensembl Genes	ENSRNOG00000053205	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000086946	ENTREZGENE
	ENSRNOT00000086946.2	UniProtKB/TrEMBL
	ENSRNOT00000103216.1	UniProtKB/TrEMBL
	ENSRNOT00000125355	ENTREZGENE
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	1.10.150.50	UniProtKB/TrEMBL
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
InterPro	Ets	UniProtKB/TrEMBL
	ETS_fam	UniProtKB/TrEMBL
	GABP_asu_N	UniProtKB/TrEMBL
	SAM_PNT	UniProtKB/TrEMBL
	SAM_type	UniProtKB/TrEMBL
	TF_GA-bd_asu	UniProtKB/TrEMBL
	Ubiquitin-rel_dom	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:363735	UniProtKB/TrEMBL
NCBI Gene	363735	ENTREZGENE
PANTHER	GA-BINDING PROTEIN ALPHA CHAIN	UniProtKB/TrEMBL
	PTHR11849	UniProtKB/TrEMBL
Pfam	Ets	UniProtKB/TrEMBL
	GABP-alpha	UniProtKB/TrEMBL
	SAM_PNT	UniProtKB/TrEMBL
PhenoGen	Gabpa	PhenoGen
PIRSF	GABP_alpha	UniProtKB/TrEMBL
PRINTS	ETSDOMAIN	UniProtKB/TrEMBL
PROSITE	ETS_DOMAIN_1	UniProtKB/TrEMBL
	ETS_DOMAIN_2	UniProtKB/TrEMBL
	ETS_DOMAIN_3	UniProtKB/TrEMBL
	PNT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000053205	RatGTEx
SMART	ETS	UniProtKB/TrEMBL
	SAM_PNT	UniProtKB/TrEMBL
Superfamily-SCOP	SAM_homology	UniProtKB/TrEMBL
	SSF46785	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	A0A8I6GML2	ENTREZGENE, UniProtKB/TrEMBL
	A6JL60	ENTREZGENE, UniProtKB/TrEMBL
	D4ACQ9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-25	Gabpa	GA binding protein transcription factor subunit alpha	Gabpa	GA binding protein transcription factor, alpha subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Gabpa	GA binding protein transcription factor, alpha subunit	Gabpa	GA repeat binding protein, alpha	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Gabpa	GA repeat binding protein, alpha	Gabpa_predicted	GA repeat binding protein, alpha (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Gabpa_predicted	GA repeat binding protein, alpha (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar