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Gene: GABPA (GA binding protein transcription factor subunit alpha) Homo sapiens
Symbol: GABPA
Name: GA binding protein transcription factor subunit alpha
RGD ID: 1321915
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and activating transcription factor binding activity. Involved in cellular response to dopamine and positive regulation of transcription by RNA polymerase II. Localizes to nuclear chromatin and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E4TF1-60; E4TF1A; GA binding protein transcription factor alpha subunit; GA binding protein transcription factor alpha subunit 60kDa; GA binding protein transcription factor, alpha subunit 60kDa; GA-binding protein alpha chain; GABP subunit alpha; human nuclear respiratory factor-2 subunit alpha; NFT2; NRF2; NRF2A; nuclear respiratory factor 2 alpha subunit; nuclear respiratory factor 2 subunit alpha; RCH04A07; transcription factor E4TF1-60
Related Pseudogenes: GABPAP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2125,734,570 - 25,772,460 (+)EnsemblGRCh38hg38GRCh38
GRCh382125,734,972 - 25,772,460 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372127,107,258 - 27,144,771 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362126,029,570 - 26,066,213 (+)NCBINCBI36hg18NCBI36
Build 342126,029,569 - 26,066,210NCBI
Celera2112,290,744 - 12,328,186 (+)NCBI
Cytogenetic Map21q21.3ENTREZGENE
HuRef2112,510,390 - 12,547,831 (+)NCBIHuRef
CHM1_12126,667,879 - 26,705,392 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GABPA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321915
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.