Erg (ETS transcription factor ERG) - Rat Genome Database

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Gene: Erg (ETS transcription factor ERG) Rattus norvegicus
Analyze
Symbol: Erg
Name: ETS transcription factor ERG
RGD ID: 621108
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell migration; heart development; and positive regulation of blood vessel remodeling. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Biomarker of pulmonary venoocclusive disease. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human ERG (ETS transcription factor ERG); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: avian erythroblastosis virus E-26 (v-ets) oncogene related; ERG, ETS transcription factor; transcriptional regulator ERG; v-ets avian erythroblastosis virus E26 oncogene; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene homolog (avian); v-ets erythroblastosis virus E26 oncogene like; v-ets erythroblastosis virus E26 oncogene like (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,678,614 - 34,900,951 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)Ensembl
Rnor_6.01135,645,317 - 35,749,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,231,276 - 39,336,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,655,563 - 35,760,055 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11135,711,805 - 35,816,365 (-)NCBI
Celera1133,675,593 - 33,777,118 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:17289661   PMID:18195090   PMID:22235125   PMID:22932696   PMID:23093599   PMID:23913826  


Genomics

Comparative Map Data
Erg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,678,614 - 34,900,951 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)Ensembl
Rnor_6.01135,645,317 - 35,749,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,231,276 - 39,336,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,655,563 - 35,760,055 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11135,711,805 - 35,816,365 (-)NCBI
Celera1133,675,593 - 33,777,118 (+)NCBICelera
Cytogenetic Map11q11NCBI
ERG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382138,367,261 - 38,661,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2138,380,027 - 38,661,780 (-)EnsemblGRCh38hg38GRCh38
GRCh372139,739,183 - 40,033,707 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362138,675,671 - 38,955,488 (-)NCBINCBI36hg18NCBI36
Build 342138,675,670 - 38,792,267NCBI
Celera2124,949,807 - 25,231,400 (-)NCBI
Cytogenetic Map21q22.2NCBI
HuRef2125,208,970 - 25,503,512 (-)NCBIHuRef
CHM1_12139,299,733 - 39,594,417 (-)NCBICHM1_1
T2T-CHM13v2.02136,750,675 - 37,045,540 (-)NCBI
Erg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,160,028 - 95,387,452 (-)NCBIGRCm39mm39
GRCm39 Ensembl1695,160,028 - 95,387,452 (-)Ensembl
GRCm381695,359,169 - 95,586,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,359,169 - 95,586,593 (-)EnsemblGRCm38mm10GRCm38
MGSCv371695,581,811 - 95,751,972 (-)NCBIGRCm37mm9NCBIm37
MGSCv361695,469,002 - 95,639,163 (-)NCBImm8
Celera1696,438,595 - 96,608,910 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.04NCBI
Erg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540737,369,641 - 37,542,751 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540737,372,471 - 37,613,674 (-)NCBIChiLan1.0ChiLan1.0
ERG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12138,087,333 - 38,366,637 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,087,339 - 38,281,403 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02124,737,829 - 25,016,378 (-)NCBIMhudiblu_PPA_v0panPan3
ERG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13133,456,902 - 33,562,704 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3133,497,209 - 33,515,272 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3132,529,920 - 32,716,050 (-)NCBI
ROS_Cfam_1.03132,767,321 - 32,953,675 (-)NCBI
ROS_Cfam_1.0 Ensembl3132,766,017 - 33,032,122 (-)Ensembl
UMICH_Zoey_3.13132,642,385 - 32,828,520 (-)NCBI
UNSW_CanFamBas_1.03132,646,486 - 32,832,235 (-)NCBI
UU_Cfam_GSD_1.03133,135,132 - 33,321,177 (-)NCBI
Erg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497132,843,364 - 33,008,541 (-)NCBI
SpeTri2.0NW_0049365004,459,298 - 4,623,290 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13202,000,985 - 202,302,577 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113201,999,237 - 202,302,572 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213212,086,250 - 212,156,873 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,327,088 - 82,611,341 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl282,326,767 - 82,447,228 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605410,177,651 - 10,463,460 (-)NCBIVero_WHO_p1.0
Erg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474525,294,832 - 25,459,683 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474525,239,356 - 25,457,533 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH140783  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21134,680,101 - 34,680,251 (+)MAPPERmRatBN7.2
Rnor_6.01135,646,805 - 35,646,954NCBIRnor6.0
Rnor_5.01139,232,764 - 39,232,913UniSTSRnor5.0
RGSC_v3.41135,655,853 - 35,656,002UniSTSRGSC3.4
Celera1133,776,679 - 33,776,828UniSTS
RH 3.4 Map11258.81UniSTS
Cytogenetic Map11q11UniSTS
MARC_15619-15620:1017174255:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21134,698,633 - 34,699,472 (+)MAPPERmRatBN7.2
Rnor_6.01135,665,362 - 35,666,200NCBIRnor6.0
Rnor_5.01139,251,055 - 39,251,893UniSTSRnor5.0
RGSC_v3.41135,674,815 - 35,675,653UniSTSRGSC3.4
Celera1133,757,607 - 33,758,445UniSTS
Cytogenetic Map11q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:53
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000039999
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 29 4 4 5 4 22 20 11
Low 3 14 53 37 14 37 8 11 74 13 21 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000039999   ⟹   ENSRNOP00000047414
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)Ensembl
Rnor_6.0 Ensembl1135,646,890 - 35,697,072 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078425   ⟹   ENSRNOP00000069853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,678,618 - 34,782,052 (-)Ensembl
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078818   ⟹   ENSRNOP00000070629
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,678,618 - 34,729,960 (-)Ensembl
Rnor_6.0 Ensembl1135,646,428 - 35,749,464 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110871   ⟹   ENSRNOP00000078490
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118689   ⟹   ENSRNOP00000079399
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119400   ⟹   ENSRNOP00000090227
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)Ensembl
RefSeq Acc Id: NM_133397   ⟹   NP_596888
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,679,812 - 34,782,034 (-)NCBI
Rnor_6.01135,646,515 - 35,749,484 (-)NCBI
Rnor_5.01139,231,276 - 39,336,495 (-)NCBI
RGSC_v3.41135,655,563 - 35,760,055 (-)RGD
Celera1133,675,593 - 33,777,118 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248142   ⟹   XP_006248204
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,782,106 (-)NCBI
Rnor_6.01135,645,317 - 35,749,637 (-)NCBI
Rnor_5.01139,231,276 - 39,336,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039087928   ⟹   XP_038943856
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,951 (-)NCBI
RefSeq Acc Id: XM_039087929   ⟹   XP_038943857
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,899,906 (-)NCBI
RefSeq Acc Id: XM_039087930   ⟹   XP_038943858
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,951 (-)NCBI
RefSeq Acc Id: XM_039087931   ⟹   XP_038943859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,950 (-)NCBI
RefSeq Acc Id: XM_039087932   ⟹   XP_038943860
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,781,923 (-)NCBI
RefSeq Acc Id: XM_039087933   ⟹   XP_038943861
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,950 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_596888   ⟸   NM_133397
- UniProtKB: Q91XV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248204   ⟸   XM_006248142
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JWE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069853   ⟸   ENSRNOT00000078425
RefSeq Acc Id: ENSRNOP00000047414   ⟸   ENSRNOT00000039999
RefSeq Acc Id: ENSRNOP00000070629   ⟸   ENSRNOT00000078818
RefSeq Acc Id: XP_038943858   ⟸   XM_039087930
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038943856   ⟸   XM_039087928
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038943861   ⟸   XM_039087933
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038943859   ⟸   XM_039087931
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038943857   ⟸   XM_039087929
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038943860   ⟸   XM_039087932
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000079399   ⟸   ENSRNOT00000118689
RefSeq Acc Id: ENSRNOP00000078490   ⟸   ENSRNOT00000110871
RefSeq Acc Id: ENSRNOP00000090227   ⟸   ENSRNOT00000119400
Protein Domains
ETS   PNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JWE9-F1-model_v2 AlphaFold A0A0G2JWE9 1-479 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698082
Promoter ID:EPDNEW_R8607
Type:multiple initiation site
Name:Erg_1
Description:ERG, ETS transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01135,749,519 - 35,749,579EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 35655358 35655359 T C snv M520/N (MCW), M520/N (2020), M520/NRrrcMcwi (2019)


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 39241051 39241052 T C snv M520/N (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621108 AgrOrtholog
BioCyc Gene G2FUF-21727 BioCyc
Ensembl Genes ENSRNOG00000001652 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000047414 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000069853 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000070629 UniProtKB/TrEMBL
  ENSRNOP00000078490 ENTREZGENE
  ENSRNOP00000079399 ENTREZGENE
  ENSRNOP00000090227 ENTREZGENE
Ensembl Transcript ENSRNOT00000039999 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000078425 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000078818 UniProtKB/TrEMBL
  ENSRNOT00000110871 ENTREZGENE
  ENSRNOT00000118689 ENTREZGENE
  ENSRNOT00000119400 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7105647 IMAGE-MGC_LOAD
InterPro Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
  SAM_type UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:170909 UniProtKB/TrEMBL
MGC_CLONE MGC:91507 IMAGE-MGC_LOAD
NCBI Gene 170909 ENTREZGENE
Pfam Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
PhenoGen Erg PhenoGen
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
  PNT UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
Superfamily-SCOP SAM_homology UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A0G2JWE9 ENTREZGENE, UniProtKB/TrEMBL
  D4A3D6_RAT UniProtKB/TrEMBL
  Q6IMZ7_RAT UniProtKB/TrEMBL
  Q91XV5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-24 Erg  ETS transcription factor ERG  Erg  ERG, ETS transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-07-26 Erg  ERG, ETS transcription factor  Erg  v-ets avian erythroblastosis virus E26 oncogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Erg  v-ets avian erythroblastosis virus E26 oncogene  Erg  v-ets erythroblastosis virus E26 oncogene homolog (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Erg  v-ets erythroblastosis virus E26 oncogene homolog (avian)  Erg  avian erythroblastosis virus E-26 (v-ets) oncogene related  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Erg  avian erythroblastosis virus E-26 (v-ets) oncogene related  Erg  v-ets erythroblastosis virus E26 oncogene like (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Erg  v-ets erythroblastosis virus E26 oncogene like (avian)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Erg  v-ets erythroblastosis virus E26 oncogene like (avian)      Symbol and Name status set to provisional 70820 PROVISIONAL