Erg (ETS transcription factor ERG) - Rat Genome Database
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Gene: Erg (ETS transcription factor ERG) Rattus norvegicus
Analyze
Symbol: Erg
Name: ETS transcription factor ERG
RGD ID: 621108
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in several processes, including mesenchyme development; positive regulation of blood vessel remodeling; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and ribonucleoprotein complex. Biomarker of pulmonary venoocclusive disease. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human ERG (ETS transcription factor ERG); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: avian erythroblastosis virus E-26 (v-ets) oncogene related; ERG, ETS transcription factor; transcriptional regulator ERG; v-ets avian erythroblastosis virus E26 oncogene; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene homolog (avian); v-ets erythroblastosis virus E26 oncogene like; v-ets erythroblastosis virus E26 oncogene like (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,678,614 - 34,900,951 (-)NCBI
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01135,645,317 - 35,749,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01139,231,276 - 39,336,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,655,563 - 35,760,055 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11135,711,805 - 35,816,365 (-)NCBI
Celera1133,675,593 - 33,777,118 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:17289661   PMID:18195090   PMID:22235125   PMID:22932696   PMID:23093599   PMID:23913826  


Genomics

Comparative Map Data
Erg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,678,614 - 34,900,951 (-)NCBI
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01135,645,317 - 35,749,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01139,231,276 - 39,336,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,655,563 - 35,760,055 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11135,711,805 - 35,816,365 (-)NCBI
Celera1133,675,593 - 33,777,118 (+)NCBICelera
Cytogenetic Map11q11NCBI
ERG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2138,380,027 - 38,661,780 (-)EnsemblGRCh38hg38GRCh38
GRCh382138,367,261 - 38,661,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372139,739,183 - 40,033,707 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh372139,739,183 - 40,033,704 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362138,675,671 - 38,955,488 (-)NCBINCBI36hg18NCBI36
Build 342138,675,670 - 38,792,267NCBI
Celera2124,949,807 - 25,231,400 (-)NCBI
Cytogenetic Map21q22.2NCBI
HuRef2125,208,970 - 25,503,512 (-)NCBIHuRef
CHM1_12139,299,733 - 39,594,417 (-)NCBICHM1_1
Erg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,160,028 - 95,387,452 (-)NCBIGRCm39mm39
GRCm381695,359,169 - 95,586,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,359,169 - 95,586,593 (-)EnsemblGRCm38mm10GRCm38
MGSCv371695,581,811 - 95,751,972 (-)NCBIGRCm37mm9NCBIm37
MGSCv361695,469,002 - 95,639,163 (-)NCBImm8
Celera1696,438,595 - 96,608,910 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.04NCBI
Erg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540737,369,641 - 37,542,751 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540737,372,471 - 37,613,674 (-)NCBIChiLan1.0ChiLan1.0
ERG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12138,087,333 - 38,366,637 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,087,339 - 38,281,403 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02124,737,829 - 25,016,378 (-)NCBIMhudiblu_PPA_v0panPan3
ERG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3133,497,209 - 33,515,272 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13133,456,902 - 33,562,704 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Erg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365004,459,298 - 4,623,290 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13202,000,985 - 202,302,577 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113201,999,237 - 202,302,572 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213212,086,250 - 212,156,873 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,327,088 - 82,611,341 (-)NCBI
ChlSab1.1 Ensembl282,326,767 - 82,447,228 (-)Ensembl
Erg
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474525,239,356 - 25,457,533 (+)NCBI

Position Markers
RH140783  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01135,646,805 - 35,646,954NCBIRnor6.0
Rnor_5.01139,232,764 - 39,232,913UniSTSRnor5.0
RGSC_v3.41135,655,853 - 35,656,002UniSTSRGSC3.4
Celera1133,776,679 - 33,776,828UniSTS
RH 3.4 Map11258.81UniSTS
Cytogenetic Map11q11UniSTS
MARC_15619-15620:1017174255:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01135,665,362 - 35,666,200NCBIRnor6.0
Rnor_5.01139,251,055 - 39,251,893UniSTSRnor5.0
RGSC_v3.41135,674,815 - 35,675,653UniSTSRGSC3.4
Celera1133,757,607 - 33,758,445UniSTS
Cytogenetic Map11q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11172720192Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)1132503169342559Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11935127454351274Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111136730644444347Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111632197346583360Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111901627290463843Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111947517979734728Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)112194422966944229Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)112194422966944229Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)112204314944444112Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112540112970401129Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112572003870720038Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112572003870720038Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112572003870720038Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112572003870720038Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112831466586994795Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113043533963186373Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)113043533986714631Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113215552082443118Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:53
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000039999
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 29 4 4 5 4 22 20 11
Low 3 14 53 37 14 37 8 11 74 13 21 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000039999   ⟹   ENSRNOP00000047414
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1135,646,890 - 35,697,072 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078425   ⟹   ENSRNOP00000069853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078818   ⟹   ENSRNOP00000070629
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1135,646,428 - 35,749,464 (-)Ensembl
RefSeq Acc Id: NM_133397   ⟹   NP_596888
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,679,812 - 34,782,034 (-)NCBI
Rnor_6.01135,646,515 - 35,749,484 (-)NCBI
Rnor_5.01139,231,276 - 39,336,495 (-)NCBI
RGSC_v3.41135,655,563 - 35,760,055 (-)RGD
Celera1133,675,593 - 33,777,118 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248142   ⟹   XP_006248204
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,782,106 (-)NCBI
Rnor_6.01135,645,317 - 35,749,637 (-)NCBI
Rnor_5.01139,231,276 - 39,336,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248143   ⟹   XP_006248205
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01135,645,317 - 35,749,637 (-)NCBI
Rnor_5.01139,231,276 - 39,336,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248145   ⟹   XP_006248207
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01135,645,317 - 35,749,636 (-)NCBI
Rnor_5.01139,231,276 - 39,336,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039087928   ⟹   XP_038943856
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,951 (-)NCBI
RefSeq Acc Id: XM_039087929   ⟹   XP_038943857
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,899,906 (-)NCBI
RefSeq Acc Id: XM_039087930   ⟹   XP_038943858
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,951 (-)NCBI
RefSeq Acc Id: XM_039087931   ⟹   XP_038943859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,950 (-)NCBI
RefSeq Acc Id: XM_039087932   ⟹   XP_038943860
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,781,923 (-)NCBI
RefSeq Acc Id: XM_039087933   ⟹   XP_038943861
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21134,678,614 - 34,900,950 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_596888   ⟸   NM_133397
- UniProtKB: Q91XV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248207   ⟸   XM_006248145
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006248205   ⟸   XM_006248143
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006248204   ⟸   XM_006248142
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JWE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069853   ⟸   ENSRNOT00000078425
RefSeq Acc Id: ENSRNOP00000047414   ⟸   ENSRNOT00000039999
RefSeq Acc Id: ENSRNOP00000070629   ⟸   ENSRNOT00000078818
RefSeq Acc Id: XP_038943858   ⟸   XM_039087930
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038943856   ⟸   XM_039087928
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038943861   ⟸   XM_039087933
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038943859   ⟸   XM_039087931
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038943857   ⟸   XM_039087929
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038943860   ⟸   XM_039087932
- Peptide Label: isoform X5
Protein Domains
ETS   PNT

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698082
Promoter ID:EPDNEW_R8607
Type:multiple initiation site
Name:Erg_1
Description:ERG, ETS transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01135,749,519 - 35,749,579EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 39241051 39241052 T C snv M520/N (KNAW)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 35655358 35655359 T C snv M520/N (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621108 AgrOrtholog
Ensembl Genes ENSRNOG00000001652 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000047414 UniProtKB/TrEMBL
  ENSRNOP00000069853 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000070629 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039999 UniProtKB/TrEMBL
  ENSRNOT00000078425 UniProtKB/TrEMBL
  ENSRNOT00000078818 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7105647 IMAGE-MGC_LOAD
InterPro Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
  SAM_type UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:170909 UniProtKB/TrEMBL
MGC_CLONE MGC:91507 IMAGE-MGC_LOAD
NCBI Gene 170909 ENTREZGENE
Pfam Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
PhenoGen Erg PhenoGen
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
  PNT UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
Superfamily-SCOP SAM_homology UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A0G2JWE9 ENTREZGENE, UniProtKB/TrEMBL
  D4A3D6_RAT UniProtKB/TrEMBL
  Q6IMZ7_RAT UniProtKB/TrEMBL
  Q91XV5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-24 Erg  ETS transcription factor ERG  Erg  ERG, ETS transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-07-26 Erg  ERG, ETS transcription factor  Erg  v-ets avian erythroblastosis virus E26 oncogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Erg  v-ets avian erythroblastosis virus E26 oncogene  Erg  v-ets erythroblastosis virus E26 oncogene homolog (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Erg  v-ets erythroblastosis virus E26 oncogene homolog (avian)  Erg  avian erythroblastosis virus E-26 (v-ets) oncogene related  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Erg  avian erythroblastosis virus E-26 (v-ets) oncogene related  Erg  v-ets erythroblastosis virus E26 oncogene like (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Erg  v-ets erythroblastosis virus E26 oncogene like (avian)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Erg  v-ets erythroblastosis virus E26 oncogene like (avian)      Symbol and Name status set to provisional 70820 PROVISIONAL